D. Young

发表

An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity.

P. Schultz, G. Spraggon, D. Young, 2011, Biochemistry.

Photoregulation of PRMT-1 Using a Photolabile Non-Canonical Amino Acid

D. Young, Elizabeth A. King, Emily M Peairs, 2021, Molecules.

Site-specific incorporation of fluorotyrosines into proteins in Escherichia coli by photochemical disguise.

A. Deiters, T. Cropp, D. Young, 2010, Biochemistry.

Fluorescence Modulation of Green Fluorescent Protein Using Fluorinated Unnatural Amino Acids

D. Young, J. Villa, Brent L. Russell, 2017, Molecules.

Development of a robust and high throughput method for profiling N-linked glycans derived from plasma glycoproteins by NanoLC-FTICR mass spectrometry.

A. Deiters, D. Muddiman, M. Bereman, 2009, Journal of proteome research.

Light-activated Cre recombinase as a tool for the spatial and temporal control of gene function in mammalian cells.

A. Deiters, D. Young, Wesleigh F. Edwards, 2009, ACS chemical biology.

An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity.

P. Schultz, G. Spraggon, D. Young, 2011, Biochemistry.

Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase.

P. Schultz, J. Stubbe, D. Young, 2011, Journal of the American Chemical Society.

Optically Triggered Immune Response through Photocaged Oligonucleotides.

A. Deiters, M. Lively, D. Young, 2015, Tetrahedron letters.

Synthesis of L-β-hydroxyaminoacids using serine hydroxymethyltransferase

D. Young, A. Saeed, 1992 .

Light-triggered polymerase chain reaction.

H. Lusic, A. Deiters, M. Lively, 2008, Chemical communications.

Evolution of cyclic peptide protease inhibitors

Peter G. Schultz, Stephen J. Benkovic, John M. Louis, 2011, Proceedings of the National Academy of Sciences.

Employing Unnatural Amino Acids in the Preparation of Bioconjugates

D. Young, T. Jacobs, Johnathan C. Maza, 2016, Synlett.

Synthesis of anthracene and azaanthracene fluorophores via [2+2+2] cyclotrimerization reactions.

A. Deiters, D. Young, Y. Zou, 2008, Organic letters.

A general approach to chemo- and regioselective cyclotrimerization reactions.

A. Deiters, D. Young, 2007, Angewandte Chemie.

Pyridines via solid-supported [2 + 2 + 2] cyclotrimerization.

A. Deiters, D. Young, R. Senaiar, 2006, Chemical communications.

Chemo‐ and Regioselectivity Enhancement in Solid‐Supported Reactions

A. Deiters, D. Young, 2011 .

Microwave-assisted synthesis of unnatural amino acids.

A. Deiters, D. Young, Jessica Torres-Kolbus, 2008, Bioorganic & medicinal chemistry letters.

Investigation of copper-free alkyne/azide 1,3-dipolar cycloadditions using microwave irradiation.

D. Young, Marshall S. Padilla, Lindsay E Chatkewitz, 2018, Bioorganic & medicinal chemistry letters.

Solid-supported [2+2+2] cyclotrimerizations.

A. Deiters, D. Young, R. Senaiar, 2006, Chemistry.

Preparation of asymmetrical polyynes by a solid-supported Glaser-Hay reaction.

Jessica S. Lampkowski, D. Young, Marshall S. Padilla, 2015, Organic & biomolecular chemistry.

Mechanistic investigation and further optimization of the aqueous Glaser-Hay bioconjugation.

D. Young, Emily M Peairs, C. Travis, 2019, Organic & biomolecular chemistry.

Development of optimized conditions for Glaser-Hay bioconjugations.

Zachary M. Nimmo, D. Young, Lindsay E Chatkewitz, 2018, Bioorganic chemistry.

Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma.

Douglas D Young, Alexander Deiters, A. Deiters, 2010, Journal of the American Chemical Society.

Cycloaddition of stable disilenes to terminal acetylenes

R. West, D. Young, 1986 .

Chemical reactions of tetramesityldisilene

J. Michl, R. West, D. Young, 1983 .

A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine.

A. Deiters, D. Young, Andrew L. McIver, 2008, Chemical communications.

Playing with the Molecules of Life.

Douglas D Young, Peter G Schultz, P. Schultz, 2018, ACS chemical biology.

Disilathiiranes: synthesis and crystal structure

R. West, D. Young, K. Haller, 1985 .

Optochemical control of RNA interference in mammalian cells

H. Lusic, A. Deiters, M. Lively, 2013, Nucleic acids research.

Photocaged T7 RNA Polymerase for the Light Activation of Transcription and Gene Function in Pro‐ and Eukaryotic Cells

A. Deiters, D. Young, C. Chou, 2010, Chembiochem : a European journal of chemical biology.

Microwave activation of enzymatic catalysis.

R. Kelly, A. Deiters, D. Young, 2008, Journal of the American Chemical Society.

Development and Optimization of Glaser-Hay Bioconjugations.

Douglas D Young, Jessica S. Lampkowski, D. Young, 2015, Angewandte Chemie.

Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization

H. Lusic, A. Deiters, M. Lively, 2009, Nucleic acids research.

Photochemical hammerhead ribozyme activation.

A. Deiters, D. Young, 2006, Bioorganic & medicinal chemistry letters.

Small-molecule inhibitors of microrna miR-21 function.

Qihong Huang, K. Gumireddy, J. Hogenesch, 2008, Angewandte Chemie.

Approaches to the modulation of miRNA maturation.

D. Young, Valerie T Tripp, Jaclyn R McKenna, 2014, Methods in molecular biology.

Development and utilization of non-coding RNA-small molecule interactions.

D. Young, Wesleigh E Georgianna, 2011, Organic & biomolecular chemistry.

Re-print of “Gas-phase acid–base properties of homocysteine, homoserine, 5-mercaptonorvaline and 5-hydroxynorvaline from the extended kinetic method”

D. Young, J. Poutsma, Valerie T Tripp, 2014 .

A light-activated DNA polymerase.

A. Deiters, D. Young, C. Chou, 2009, Angewandte Chemie.

Gene Silencing in Mammalian Cells with Light‐Activated Antisense Agents

H. Lusic, A. Deiters, M. Lively, 2008, Chembiochem : a European journal of chemical biology.

Synthesis and incorporation of a caged tyrosine amino acid possessing a bioorthogonal handle.

D. Young, Marshall S. Padilla, Christopher A Farley, 2016, Tetrahedron letters.

Site-specific incorporation of a fluorescent terphenyl unnatural amino acid.

Jessica S. Lampkowski, D. Young, Diya M. Uthappa, 2015, Bioorganic & medicinal chemistry letters.

Photochemical control of biological processes.

Douglas D Young, Alexander Deiters, A. Deiters, 2007, Organic & biomolecular chemistry.

The effect of microwave irradiation on DNA hybridization.

A. Deiters, D. Young, W. Edwards, 2009, Organic & biomolecular chemistry.

Application of the Solid-Supported Glaser-Hay Reaction to Natural Product Synthesis.

Jessica S. Lampkowski, D. Young, Johnathan C. Maza, 2016, The Journal of organic chemistry.

Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells.

Douglas D Young, Alexander Deiters, A. Deiters, 2010, Journal of the American Chemical Society.

Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization.

A. Deiters, D. Young, R. Senaiar, 2007, The Journal of organic chemistry.

Photochemical DNA activation.

H. Lusic, A. Deiters, M. Lively, 2007, Organic letters.

Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP.

K. Hahn, A. Karginov, N. Dokholyan, 2011, Journal of the American Chemical Society.

Expanding the scope of alkyne-mediated bioconjugations utilizing unnatural amino acids.

Zachary M. Nimmo, D. Young, Johnathan C. Maza, 2016, Chemical communications.

Optimization of Solid-Supported Glaser-Hay Reactions in the Microwave

Jessica S. Lampkowski, D. Young, Johnathan C. Maza, 2015, Molecules.

Light‐Regulated RNA–Small Molecule Interactions

A. Deiters, D. Young, 2008, Chembiochem : a European journal of chemical biology.

Site-specific protein immobilization using unnatural amino acids.

Benjamin K. Raliski, D. Young, Christina A. Howard, 2014, Bioconjugate chemistry.

Site-Speci fi c Protein Immobilization Using Unnatural Amino Acids

Benjamin K. Raliski, D. Young, Christina A. Howard, 2014 .

Using unnatural amino acid mutagenesis to probe the regulation of PRMT1.

Graham M. West, P. Schultz, Heather L. Rust, 2014, ACS Chemical Biology.

Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations.

Benjamin K. Raliski, M. Freedman, D. Young, 2015, Bioconjugate chemistry.

Development of rapid microwave-mediated and low-temperature bacterial transformations

D. Young, Valerie T Tripp, Johnathan C. Maza, 2013, Journal of chemical biology.

Photochemical activation of protein expression in bacterial cells.

A. Deiters, D. Young, 2007, Angewandte Chemie.

Utilizing Unnatural Amino Acids To Illustrate Protein Structure–Function Relationships: An Experiment Designed for an Undergraduate Biochemistry Laboratory

D. Young, L. Landino, Johnathan C. Maza, 2016 .

Photosensitive GFP mutants containing an azobenzene unnatural amino acid.

D. Young, Marshall S Padilla, 2015, Bioorganic & medicinal chemistry letters.

Discovery of small molecule modifiers of microRNAs for the treatment of HCV infection.

D. Young, Valerie T Tripp, 2014, Methods in molecular biology.

Photocaged T7 RNA Polymerase for the Light Activation of Transcription and Gene Function in Pro‐ and Eukaryotic Cells

A. Deiters, D. Young, Chungjung Chou, 2010, Chembiochem : a European journal of chemical biology.

Light-activated Cre recombinase as a tool for the spatial and temporal control of gene function in mammalian cells.

A. Deiters, D. Young, W. Edwards, 2009, ACS chemical biology.

Using unnatural amino acid mutagenesis to probe the regulation of PRMT1.

Graham M. West, P. Schultz, Heather L. Rust, 2014, ACS chemical biology.

Synthesis of anthracene and azaanthracene fluorophores via [2+2+2] cyclotrimerization reactions.

A. Deiters, D. Young, Y. Zou, 2008, Organic letters.

Synthetase polyspecificity as a tool to modulate protein function.

P. Schultz, N. Turro, D. Young, 2011, Bioorganic & medicinal chemistry letters.

Expanding the scope of alkyne-mediated bioconjugations utilizing unnatural amino acids.

Zachary M. Nimmo, D. Young, Johnathan C. Maza, 2016, Chemical communications.

Utilization of alkyne bioconjugations to modulate protein function.

D. Young, Johnathan C. Maza, Megha A Vipani, 2017, Bioorganic & medicinal chemistry letters.