C. Menet

发表

Type II kinase inhibitors: an opportunity in cancer for rational design.

R. Geney, J. Blanc, C. Menet, 2013, Anti-cancer agents in medicinal chemistry.

Expediting drug discovery: recent advances in fast medicinal chemistry--optimization of hits and leads.

P. Edwards, C. Menet, M. Andrews, 2006, Current opinion in drug discovery & development.

Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis.

T. Christophe, C. Menet, B. Allart, 2021, Journal of medicinal chemistry.

Regio- and Diastereoselective Functionalization of 3-Amino-hexahydrooxazoninones

J. Wouters, G. Verniest, C. Menet, 2018, European Journal of Organic Chemistry.

Toward selective TYK2 inhibitors as therapeutic agents for the treatment of inflammatory diseases.

C. Menet, 2014, Pharmaceutical patent analyst.

Accelerating GPCR Drug Discovery With Conformation-Stabilizing VHHs

V. Jaakola, Stephane De Cesco, Sarah Triest, 2022, Frontiers in Molecular Biosciences.

Triazolopyridines as selective JAK1 inhibitors: from hit identification to GLPG0634.

L. Nelles, R. Geney, E. M. van der Aar, 2014, Journal of medicinal chemistry.

Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases

L. Nelles, B. Smets, K. Conrath, 2013, The Journal of Immunology.

Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor

P. D. de Witte, A. Siekierska, Daniëlle Copmans, 2022, Frontiers in Pharmacology.

Selective Inhibitor of JAK 1 , for the Preclinical Characterization of GLPG 0634 , a Feyen and

Vandeghinste, B. Smets, K. Conrath, 2013 .

2,3-Dihydroisoindolones by cyclisation and rearomatisation of lithiated benzamides

C. Menet, J. Clayden, 2003 .

Asymmetric deprotonation and dearomatising cyclisation of N-benzyl benzamides using chiral lithium amides: formal synthesis of (-)-kainic acid.

C. Menet, J. Clayden, D. Mansfield, 2002, Chemical communications.

Synthesis of α-methyl kainic acid by stereospecific lithiation-dearomatizing cyclization of a chiral benzamide

C. Menet, J. Clayden, F. E. Knowles, 2003 .

Synthesis of (-)-kainic acid using chiral lithium amides in an asymmetric dearomatizing cyclization

C. Menet, K. Tchabanenko, J. Clayden, 2002 .

meso-Selective' functionalisation of N-benzyl-α-methylbenzylamine derivatives by α-lithiation and alkylation

C. Menet, J. Clayden, R. Bragg, 2002 .

Dearomatizing Anionic Cyclization of Substituted N-Cumyl-N-benzylbenzamides on Treatment with LDA: Synthesis of Partially Saturated Substituted Isoindolones.

C. Menet, J. Clayden, D. Mansfield, 2001 .

Progress toward JAK1-selective inhibitors.

C. Menet, Oscar Mammoliti, M. López-Ramos, 2015, Future medicinal chemistry.

Advances in the discovery of selective JAK inhibitors.

R. Geney, C. Menet, Raphaël Geney, 2013, Progress in medicinal chemistry.

IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases

S. Dupont, P. Fallon, K. Eyerich, 2023, Science Translational Medicine.

Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases.

N. Triballeau, Denis Bucher, T. Christophe, 2021, Journal of medicinal chemistry.

Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis.

K. Conrath, C. Menet, M. Andrews, 2021, Journal of medicinal chemistry.

A Dual Inhibition, a Better Solution: Development of a JAK1/TYK2 inhibitor.

C. Menet, 2018, Journal of medicinal chemistry.

Design and synthesis of APTCs (aminopyrrolidinetricarboxylic acids): identification of a new group III metabotropic glutamate receptor selective agonist.

N. Triballeau, F. Acher, H. Bertrand, 2006, Bioorganic & medicinal chemistry letters.

Wandering beyond small molecules: peptides as allosteric protein modulators.

C. Menet, S. Ballet, Charlotte Martin, 2021, Trends in pharmacological sciences.