Shinichiro Fuse

发表

Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexes.

Masamichi Ishizaka, Hiroshi Yanagawa, Hideaki Takashima, 2005, Genome research.

Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design.

P. Sliż, S. Walker, D. Kahne, 2008, ACS chemical biology.

Continuous in situ generation and reaction of phosgene in a microflow system.

Takashi Takahashi, Shinichiro Fuse, Shinichiro Fuse, 2011, Chemical communications.

Peptide Chain Elongation Using Unprotected Amino Acids in a Micro-flow Reactor.

Shinichiro Fuse, Hiroyuki Nakamura, Koshiro Masuda, 2019, Chemistry.

Efficient Amide Bond Formation through a Rapid and Strong Activation of Carboxylic Acids in a Microflow Reactor**

Shinichiro Fuse, Y. Mifune, Takashi Takahashi, 2013, Angewandte Chemie.

Micro-flow synthesis and structural analysis of sterically crowded diimine ligands with five aryl rings

Takashi Takahashi, Shinichiro Fuse, Y. Konishi, 2013, Beilstein journal of organic chemistry.

Rapid Synthesis of Thiophene-Based, Organic Dyes for Dye-Sensitized Solar Cells (DSSCs) by a One-Pot, Four-Component Coupling Approach.

Y. Wada, S. Hayase, Y. Ogomi, 2015, Chemistry.

Synthesis of EDOT-containing organic dyes via one-pot, four-component Suzuki–Miyaura coupling and the evaluation of their photovoltaic properties

Y. Wada, S. Hayase, Y. Ogomi, 2014 .

Efficient Synthesis of Natural Products Aided by Automated Synthesizers and Microreactors

Takashi Takahashi, Shinichiro Fuse, Kazuhiro Machida, 2012 .

Photodynamic therapy using a cytotoxic photosensitizer porphyrus envelope that targets the cell membrane.

Y. Kaneda, K. Awazu, Shinichiro Fuse, 2017, Photodiagnosis and photodynamic therapy.

Elucidating the mode of action for thiophene-based organic D-π-A sensitizers for use in photodynamic therapy.

S. Okazaki, Shinichiro Fuse, Hiroyuki Nakamura, 2019, Bioorganic & medicinal chemistry.

The design, synthesis, and evaluation of organic dithienopyrrole-based D-π-A dyes for use as sensitizers in photodynamic therapy.

Shinichiro Fuse, Hiroyuki Nakamura, Shinichi Sato, 2018, Bioorganic & medicinal chemistry letters.

Thiophene‐Based Organic D–π–A Dyes as Potent Sensitizers for Photodynamic Therapy

S. Okazaki, Shinichiro Fuse, Hiroyuki Nakamura, 2017 .

Investigation into the influence of an acrylic acid acceptor in organic D-π-A sensitizers against phototoxicity.

Shinichiro Fuse, Hiroyuki Nakamura, Shinichi Sato, 2020, Bioorganic & medicinal chemistry.

Synthesis of bicyclic enediynes that possess a photosensitive triggering device and exhibit strong DNA cleaving activity.

Yoshikazu Tanaka, H. Sugiyama, T. Doi, 2010, Chemical communications.

Sequential S(N)Ar Reaction/Suzuki-Miyaura Coupling/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles.

H. Uekusa, Takashi Takahashi, Shinichiro Fuse, 2015, Chemistry, an Asian journal.

Facile, One‐Step Synthesis of 5‐Substituted Thieno[3,4‐c]pyrrole‐4,6‐dione by Palladium‐Catalyzed Carbonylative Amidation

R. Takahashi, Takashi Takahashi, Shinichiro Fuse, 2015 .

Directing/protecting-group-free synthesis of tetraaryl-substituted pyrazoles through four direct arylations on an unsubstituted pyrazole scaffold.

H. Uekusa, Shinichiro Fuse, Hiroshi Tanaka, 2015, Chemistry.

One-pot, three-component coupling approach to the synthesis of α-iminocarboxamides.

Takashi Takahashi, H. Masui, Shinichiro Fuse, 2012, Organic letters.

CD80 and CD86 Control Antiviral CD8+ T-Cell Function and Immune Surveillance of Murine Gammaherpesvirus 68

E. Usherwood, J. J. Obar, E. Leung, 2006, Journal of Virology.

The Synthesis of trans-Flavan-3-ol Gallates by Regioselective Oxidative Etherification and Their Cytotoxicity Mediated by 67 LR.

H. Tachibana, Shinichiro Fuse, Hiroshi Tanaka, 2016, Chemistry.

Highly stable and efficient mRNA templates for mRNA-protein fusions and C-terminally labeled proteins.

T. Sawasaki, H. Takashima, E. Miyamoto-Sato, 2003, Nucleic acids research.

Total synthesis of spiruchostatin B aided by an automated synthesizer.

K. Shin‐ya, T. Doi, M. Takagi, 2011, Organic & biomolecular chemistry.

Single-Step, Rapid, and Mild Synthesis of β-Amino Acid N-Carboxy Anhydrides Using Micro-Flow Technology.

Shinichiro Fuse, Hiroyuki Nakamura, Yuma Otake, 2019, Chemistry, an Asian journal.

Rapid and Mild Synthesis of Amino Acid N-Carboxy Anhydrides: Basic-to-Acidic Flash Switching in a Microflow Reactor.

Shinichiro Fuse, Hiroyuki Nakamura, Yuma Otake, 2018, Angewandte Chemie.

Rapid and Mild Synthesis of Amino Acid N-Carboxy Anhydrides: Basic-to-Acidic Flash Switching in a Microflow Reactor.

Shinichiro Fuse, Hiroyuki Nakamura, Yuma Otake, 2018, Angewandte Chemie.

Differential requirements for CD80/86-CD28 costimulation in primary and memory CD4 T cell responses to vaccinia virus.

E. Usherwood, Shinichiro Fuse, Weijun Zhang, 2011, Cellular immunology.

Asymmetric Total Synthesis of ent-Pyripyropene A.

K. Shin‐ya, T. Doi, M. Izumikawa, 2015, Chemistry.

Recent Advances in the Solid- and Solution-Phase Synthesis of Peptides and Proteins Using Microflow Technology

H. Masui, Shinichiro Fuse, 2022, Organic Process Research & Development.

Immune responses against persistent viral infections: possible avenues for immunotherapeutic interventions.

E. Usherwood, Shinichiro Fuse, M. Molloy, 2008, Critical reviews in immunology.

6-Azido-6-deoxy-l-idose as a Hetero-Bifunctional Spacer for the Synthesis of Azido-Containing Chemical Probes.

Y. Yamaguchi, H. Tachibana, Shinichiro Fuse, 2016, Chemistry.

Synthesis of 3-Hydroxy-4-Substituted Picolinonitriles from 4-Propargylaminoisoxazoles via Stepwise and One-Pot Isoxazolopyridine Formation/N–O Bond Cleavage Sequence

Shinichiro Fuse, Hiroyuki Nakamura, S. Yugandar, 2018, ACS Omega.

JBIR-56 and JBIR-57, 2(1H)-pyrazinones from a marine sponge-derived Streptomyces sp. SpD081030SC-03.

K. Shin‐ya, T. Doi, M. Takagi, 2011, Journal of natural products.

Photochemical Conversion of Isoxazoles to 5-Hydroxyimidazolines.

Shinichiro Fuse, Hiroyuki Nakamura, T. Morita, 2020, Organic letters.

Gold(I)-Catalyzed Intramolecular SEAr Reaction: Efficient Synthesis of Isoxazole-Containing Fused Heterocycles.

Shinichiro Fuse, Hiroyuki Nakamura, T. Morita, 2018, Organic letters.

Step-by-Step Multifunctionalization of Isoxazoles Based On SEAr Reactions and C–H Direct Arylations

Shinichiro Fuse, Hiroyuki Nakamura, T. Morita, 2017, Synthesis.

Generation of an 4-Isoxazolyl Anion Species: Facile Access to Multifunctionalized Isoxazoles.

Shinichiro Fuse, Hiroyuki Nakamura, T. Morita, 2016, Angewandte Chemie.

Regioselective, One-Pot, Three-Component Synthesis of 1,3,4- and 1,3,5-Triarylpyrazoles from 1- and 2-Aryl-1-alkenyl Sulfones

Takashi Takahashi, Shinichiro Fuse, Hiroshi Tanaka, 2015 .

A micro-flow rapid dual activation approach for urethane-protected α-amino acid N-carboxyanhydride synthesis.

Shinichiro Fuse, N. Sugisawa, Ren Okabe, 2022, Organic & biomolecular chemistry.

Rapid and Mild One‐Flow Synthetic Approach to Unsymmetrical Sulfamides Guided by Bayesian Optimization

R. Krems, Hiroki Sugisawa, Shinichiro Fuse, 2021, Chemistry–Methods.

Micro-Flow N-Acylation Using Highly Electrophilic Acyl Ammonium Cations for Peptide and Urethane-Protected N-Carboxyanhydride Syntheses

H. Masui, Shinichiro Fuse, 2022, Journal of Synthetic Organic Chemistry, Japan.

Integrated Micro‐Flow Synthesis Based on Photochemical Wolff Rearrangement

Shinichiro Fuse, Hiroyuki Nakamura, Yuma Otake, 2017 .

Design and synthesis of 2-phenyl-1,4-dioxa-spiro[4.5]deca-6,9-dien-8-ones as potential anticancer agents starting from cytotoxic spiromamakone A.

K. Shin‐ya, Masahiro Tanaka, T. Hirokawa, 2013, European journal of medicinal chemistry.

Synthesis of N-Allyloxycarbonyl 3,5-Dihydroxyphenylglycine via Photochemical Wolff Rearrangement—Nucleophilic Addition Sequence in a Micro-Flow Reactor

Shinichiro Fuse, Hiroshi Tanaka, Y. Mifune, 2014, Journal of Flow Chemistry.

Recent progresses in the synthesis of functionalized isoxazoles

Shinichiro Fuse, Hiroyuki Nakamura, S. Yugandar, 2018 .

Anti-influenza virus compound from Streptomyces sp. RI18.

K. Shin‐ya, Masahiro Tanaka, A. Kawaguchi, 2010, Organic letters.

Development of 1-aryl-3-furanyl/thienyl-imidazopyridine templates for inhibitors against hypoxia inducible factor (HIF)-1 transcriptional activity.

Shinichiro Fuse, Yasunobu Asawa, Hiroyuki Nakamura, 2016, Bioorganic & medicinal chemistry letters.

Continuous-flow synthesis of vitamin D3.

Hayato Yoshida, Takayuki Doi, T. Doi, 2010, Chemical communications.

Regioselective, One-Pot, Three-Component Synthesis of 1,3,4- and 1,3,5-Triarylpyrazoles from 1- and 2-Aryl-1-alkenyl Sulfones.

Takashi Takahashi, Shinichiro Fuse, Hiroshi Tanaka, 2015 .

Development of dual targeting inhibitors against aggregations of amyloid-β and tau protein.

H. Sugimoto, Shinichiro Fuse, Takashi Takahashi, 2014, European journal of medicinal chemistry.

Elucidation of the structure-property relationship of p-type organic semiconductors through rapid library construction via a one-pot, Suzuki-Miyaura coupling reaction.

S. Yoshikawa, A. Wakamiya, H. Masui, 2014, ACS combinatorial science.

Elucidating the structure-property relationships of donor-π-acceptor dyes for dye-sensitized solar cells (DSSCs) through rapid library synthesis by a one-pot procedure.

Y. Wada, S. Hayase, R. Katoh, 2014, Chemistry.

Construction of the ABC Ring System of Taxanes via Stereoselective One-Pot Three-Component Coupling and Intramolecular Alkylation of a Protected Cyanohydrin Ether

T. Doi, Takashi Takahashi, Shinichiro Fuse, 2010 .

Design, synthesis and evaluation of carbamate-modified (-)-N(1)-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors.

T. Kihara, A. Akaike, T. Niidome, 2010, Bioorganic & medicinal chemistry letters.

Design, synthesis, evaluation and QSAR analysis of N(1)-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors.

Yasushi Okuno, Akinori Akaike, Y. Okuno, 2010, Bioorganic & medicinal chemistry letters.

Stereoselective one-pot three-component coupling approach towards the synthesis of the AC ring system of taxanes

T. Doi, Takashi Takahashi, Shinichiro Fuse, 2009 .

Total synthesis of feglymycin based on a linear/convergent hybrid approach using micro-flow amide bond formation

Shinichiro Fuse, Hiroyuki Nakamura, Hiroshi Tanaka, 2016, Nature Communications.

A formal total synthesis of taxol aided by an automated synthesizer.

T. Doi, Takashi Takahashi, Shinichiro Fuse, 2006, Chemistry, an Asian journal.

Rapid and Structurally Diverse Synthesis of Multi‐Substituted β‐Keto Amide Derivatives Based on a Dioxinone Scaffold

Takashi Takahashi, Shinichiro Fuse, Kazuya Oosumi, 2014 .

Continuous-flow synthesis of activated vitamin D3 and its analogues.

Takashi Takahashi, Shinichiro Fuse, N. Tanabe, 2012, Organic & biomolecular chemistry.

Cluster Preface: Integrated Synthesis Using Continuous-Flow Technologies

Shinichiro Fuse, 2020, Synlett.

Ti(III)-catalyzed radical cyclization of 6,7-epoxygeranyl acetate

T. Doi, Takashi Takahashi, Shinichiro Fuse, 2004 .

The α-Glycosidation of Partially Unprotected N-Acetyl and N-Glycolyl Sialyl Donors in the Absence of a Nitrile Solvent Effect.

Y. Yamaguchi, J. Uzawa, Shinichiro Fuse, 2016, Chemistry.

The Design, Synthesis, and Evaluation of 1,5,7-Trisubstituted-3-Pyridyl-Xanthones for Use as Insecticides Starting from Pyripyropene A.

S. Ōmura, H. Uekusa, Takashi Takahashi, 2016, Chemistry.

Efficient Synthesis of Biologically Active Peptides Based on Micro-flow Amide Bond Formation

Shinichiro Fuse, 2021, Middle Molecular Strategy.

N‐Methylated Peptide Synthesis via Generation of an Acyl N‐Methylimidazolium Cation Accelerated by a Brønsted Acid

S. Kawauchi, Shinichiro Fuse, Hiroyuki Nakamura, 2020 .

N-Methylated Peptide Synthesis via Acyl N-Methylimidazolium Cation Generation Accelerated by a Brønsted Acid.

S. Kawauchi, Shinichiro Fuse, Hiroyuki Nakamura, 2020, Angewandte Chemie.

A rapid and clean synthetic approach to cyclic peptides via micro-flow peptide chain elongation and photochemical cyclization: synthesis of a cyclic RGD peptide.

Shinichiro Fuse, Hiroyuki Nakamura, Y. Mifune, 2016, Organic & biomolecular chemistry.

Ribosomal Synthesis of Backbone‐Macrocyclic Peptides Containing γ‐Amino Acids

T. Doi, H. Suga, Takashi Takahashi, 2011, Chembiochem : a European journal of chemical biology.

Micro-flow synthesis of β-amino acid derivatives via a rapid dual activation approach.

Shinichiro Fuse, Hiroyuki Nakamura, N. Sugisawa, 2020, Chemical communications.

Development and application of a solution-phase automated synthesizer, 'ChemKonzert'.

Tohru Sugawara, Kazuhiro Machida, Takashi Takahashi, 2010, Chemical & pharmaceutical bulletin.

Rapid assembly of resorcylic acid lactone frameworks through sequential palladium-catalyzed coupling reactions.

Takashi Takahashi, Shinichiro Fuse, Sakae Sugiyama, 2010, Chemistry, an Asian journal.

An iterative approach to the synthesis of thiophene-based organic dyes

Takashi Takahashi, Shinichiro Fuse, H. Yoshida, 2012 .

Total synthesis and stereochemistry revision of mannopeptimycin aglycone.

K. Shin‐ya, T. Doi, M. Izumikawa, 2014, Journal of the American Chemical Society.

Solution-phase automated synthesis of an α-amino aldehyde as a versatile intermediate

Takashi Takahashi, H. Masui, Shinichiro Fuse, 2017, Beilstein journal of organic chemistry.

Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity.

S. Kizaka-Kondoh, Shinichiro Fuse, Hiroyuki Nakamura, 2019, Bioorganic & medicinal chemistry.

Functional and structural analysis of a key region of the cell wall inhibitor moenomycin.

S. Walker, D. Kahne, Shinichiro Fuse, 2010, ACS chemical biology.

Palladium-catalyzed double carbonylation-based diversity-oriented synthesis of 3,4-dihydroisoquinoline-1-carboxamides

Takashi Takahashi, H. Masui, Shinichiro Fuse, 2015 .

Three-component coupling approach toward the synthesis of a resorcylic acid lactone framework

Takashi Takahashi, Shinichiro Fuse, Sakae Sugiyama, 2011 .

Complete characterization of the seventeen step moenomycin biosynthetic pathway.

S. Walker, D. Kahne, B. Ostash, 2009, Biochemistry.

Cytokine working group study of lymphodepleting chemotherapy, interleukin-2, and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma: clinical outcomes and peripheral-blood cell recovery.

M. Atkins, T. Crocenzi, J. Fisher, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Peptide Synthesis Utilizing Micro-flow Technology.

Shinichiro Fuse, Hiroyuki Nakamura, Yuma Otake, 2018, Chemistry, an Asian journal.

Recall Responses by Helpless Memory CD8+ T Cells Are Restricted by the Up-Regulation of PD-11

H. Yagita, E. Usherwood, Shinichiro Fuse, 2009, The Journal of Immunology.

Gammaherpesvirus Persistence Alters Key CD8 T-Cell Memory Characteristics and Enhances Antiviral Protection

E. Usherwood, E. Leung, Shinichiro Fuse, 2006, Journal of Virology.

Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines.

M. Ernstoff, C. Ahonen, R. Noelle, 2008, Blood.

Donor–acceptor polymers containing thiazole-fused benzothiadiazole acceptor units for organic solar cells

R. Murdey, Y. Murata, A. Wakamiya, 2019, RSC advances.

Control of Memory CD8+ T Cell Differentiation by CD80/CD86-CD28 Costimulation and Restoration by IL-2 during the Recall Response1

E. Usherwood, Shinichiro Fuse, Weijun Zhang, 2008, The Journal of Immunology.

Recent advances in the integrated micro-flow synthesis containing photochemical reactions

Shinichiro Fuse, Hiroyuki Nakamura, Yuma Otake, 2018 .

An Efficient Synthesis of a Cyclic Ether Key Intermediate for 9-Membered Masked Enediyne Using an Automated Synthesizer

T. Doi, Yoshikazu Tanaka, Takashi Takahashi, 2009 .

Recent Advances in Continuous-Flow Reactions Using Metal-Free Homogeneous Catalysts

Shinichiro Fuse, Hiroyuki Nakamura, N. Sugisawa, 2020, Catalysts.

Rapid Synthesis of D-A'-π-A Dyes through a One-Pot Three-Component Suzuki-Miyaura Coupling and an Evaluation of their Photovoltaic Properties for Use in Dye-Sensitized Solar Cells.

Y. Wada, S. Hayase, Y. Ogomi, 2016, Chemistry.

Simultaneous Analysis of In Vivo CD8+ T Cell Cytotoxicity Against Multiple Epitopes using Multicolor Flow Cytometry

E. Usherwood, Shinichiro Fuse, 2007, Immunological investigations.

CD8+ T Cell Dysfunction and Increase in Murine Gammaherpesvirus Latent Viral Burden in the Absence of 4-1BB Ligand1

H. Yagita, E. Usherwood, Shinichiro Fuse, 2007, The Journal of Immunology.

CD8 T Cell Dysfunction and Increase in Murine Gammaherpesvirus Latent Viral Burden in the Absence of 4-1BB Ligand

Usherwood, H. Yagita, Shinichiro Fuse, 2007 .

One-Flow Syntheses of Unsymmetrical Sulfamides and N-Substituted Sulfamate Esters.

Hiroki Sugisawa, Shinichiro Fuse, N. Sugisawa, 2023, Organic Letters.

Verification of preparations of (1H-indol-3-yl)methyl electrophiles and development of their microflow rapid generation and substitution

H. Masui, Shinichiro Fuse, Sena Kanda, 2023, Communications Chemistry.

Design, synthesis, and evaluation of azo D-π-A dyes as photothermal agents.

S. Kawauchi, Shinichiro Fuse, Hiroyuki Nakamura, 2019, Organic & biomolecular chemistry.

Synthesis and Evaluation of Thiophene‐Based Organic Dyes Containing a Rigid and Nonplanar Donor with Secondary Electron Donors for Use in Dye‐Sensitized Solar Cells

R. Takahashi, Y. Wada, M. Maitani, 2016 .

D–π–A Dyes that Contain New Hydantoin Anchoring Groups for Dye‐Sensitized Solar Cells

Y. Wada, S. Hayase, Y. Ogomi, 2018 .

Synthesis of Pyrazolofuropyrazine via One-Pot SNAr Reaction and Intramolecular Direct C–H Arylation

Shinichiro Fuse, Hiroyuki Nakamura, Shinichi Sato, 2018, Synthesis.

Synthesis of Asymmetrical‐Terminally Bifunctionlized Alkanes by Sequential Suzuki–Miyaura Coupling Using B‐Thexylboracyclanes

Shinichiro Fuse, Hiroshi Tanaka, Ryota Suzuki, 2016 .

M. Atkins, T. Crocenzi, J. Fisher, 2010, Journal of Clinical Oncology.

Publication list

Wakamiya, R. Murdey, Y. Shimakawa, 2019, Journal of Physics: Conference Series.

Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines.

M. Ernstoff, C. Ahonen, R. Noelle, 2008, Blood.

Rapid and column-chromatography-free peptide chain elongation via a one-flow, three-component coupling approach

Shinichiro Fuse, A. Ando, N. Sugisawa, 2023, Chemical science.

Combinatorial synthesis and evaluation of α-iminocarboxamide-nickel(II) catalysts for the copolymerization of ethylene and a polar monomer.

H. Masui, Shinichiro Fuse, Akio Tannna, 2012, ACS combinatorial science.

Publication List

R. Murdey, P. Ekanayake, Y. Murata, 2010 .