J. Janey

发表

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Paul N. Devine, Gjalt W. Huisman, E. Mundorff, 2010, Science.

Synergistic Solvation Effects: Enhanced Compound Solubility Using Binary Solvent Mixtures

J. Janey, Jun Qiu, J. Albrecht, 2019, Organic Process Research & Development.

Zinc Acetate-Promoted Buchwald-Hartwig Couplings of Heteroaromatic Amines.

Martin D. Eastgate, J. Janey, E. Simmons, 2017, The Journal of organic chemistry.

9.13 Industrially Relevant Enzymatic Reductions

Jeffrey C. Moore, S. Pannuri, C. Savile, 2012 .

Synthesis of the HCV protease inhibitor Vaniprevir (MK-7009) using ring-closing metathesis strategy.

J. Janey, Cheng-yi Chen, Hongmei Li, 2012, The Journal of organic chemistry.

Practical Synthesis of A Macrocyclic HCV Protease Inhibitor: A High-Yielding Macrolactam Formation

Paul N. Devine, D. Tellers, D. Zewge, 2014 .

Solubility Behaviors and Correlations of Common Solvent–Antisolvent Systems

J. Janey, Jun Qiu, J. Albrecht, 2020 .

Recent Advances in Catalytic, Enantioselective α Aminations and α Oxygenations of Carbonyl Compounds

J. Janey, 2005 .

Development of a Platform for Near-Infrared Photoredox Catalysis

Martin D. Eastgate, J. Janey, Michael A. Schmidt, 2020, ACS central science.

Chiral Salen-Aluminum Complexes as Catalysts for Enantioselective Aldol Reactions of Aldehydes and 5-Alkoxyoxazoles: An Efficient Approach to the Asymmetric Synthesis ofsyn andantiβ-Hydroxy-α-amino Acid Derivatives

Davidr . Evans, J. Tedrow, J. Janey, 2001 .

Spin-Forbidden Excitation Enables Infrared Photoredox Catalysis

Martin D. Eastgate, J. Janey, Michael A. Schmidt, 2020 .

The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future

Ling Li, Emma McInturff, Ke Wang, 2019, Organic Process Research & Development.

Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes.

Jason M. Stevens, Thomas M. Razler, Antonio Ramirez, 2018, Organic letters.

High-Throughput Extractions: A New Paradigm for Workup Optimization in Pharmaceutical Process Development

J. Janey, Zhongmin Xu, Kristy Tran, 2016 .

Scalable Asymmetric Synthesis of MK-8998, a T-Type Calcium Channel Antagonist.

L. Tan, Jeffrey C. Moore, J. Janey, 2021, The Journal of organic chemistry.

A biocatalytic/reductive etherification approach to substituted piperidinyl ethers

M. Truppo, J. Janey, J. Arredondo, 2014 .

C(2)-symmetric Cu(II) complexes as chiral lewis acids. Catalytic, enantioselective cycloadditions of silyl ketenes.

J. Janey, D. Evans, 2001, Organic letters.

Chiral C2 -Symmetric CuII Complexes as Catalysts for Enantioselective Hetero-Diels-Alder Reactions.

E. Olhava, Davidr . Evans, J. Janey, 1998, Angewandte Chemie.

Bayesian reaction optimization as a tool for chemical synthesis

Ryan P. Adams, Jason M. Stevens, Farhan N. Damani, 2021, Nature.

A practical synthesis of 5-lipoxygenase inhibitor MK-0633.

I. Davies, F. Gosselin, M. Palucki, 2010, The Journal of organic chemistry.

Proline-catalyzed, asymmetric mannich reactions in the synthesis of a DPP-IV inhibitor.

J. Armstrong, J. Janey, Y. Hsiao, 2006, The Journal of organic chemistry.

Direct Lewis Acid Catalyzed Conversion of Enantioenriched N-Acyloxazolidinones to Chiral Esters, Amides, and Acids.

Jason M. Stevens, J. Janey, G. Beutner, 2018, The Journal of organic chemistry.

A Biocatalytic/Reductive Etherification Approach to Substituted Piperidinyl Ethers.

M. Truppo, J. Janey, J. Arredondo, 2014 .

Racemic and asymmetric Diels-Alder reactions of 1-(2-oxazolidinon-3-yl)-3-siloxy-1,3-butadienes.

S. Kozmin, J. Janey, V. Rawal, 2000, The Journal of organic chemistry.

1-Amino-3-siloxy-1,3-butadienes: Highly Reactive Dienes for the Diels-Alder Reaction.

S. Kozmin, J. Janey, V. Rawal, 1999, The Journal of organic chemistry.

Enantioselective Synthesis of a γ-Secretase Modulator via Vinylogous Dynamic Kinetic Resolution.

Jun Yu Li, Thomas E. La Cruz, Antonio Ramirez, 2018, The Journal of organic chemistry.

C2‐Symmetric Cu(II) Complexes as Chiral Lewis Acids. Catalytic Enantioselective Cycloadditions of Silyl Ketenes.

Davidr . Evans, J. Janey, 2010 .

Recent Advances in Catalytic, Enantioselective α Aminations and α Oxygenations of Carbonyl Compounds

J. Janey, 2005 .

Raney-Co mediated reductive cyclization of an alpha,beta-unsaturated nitrile.

C. Orella, E. Njolito, I. Davies, 2008, The Journal of organic chemistry.

Chiral C2-Symmetric CuII Complexes as Catalysts for Enantioselective Hetero-Diels—Alder Reactions.

E. Olhava, Davidr . Evans, J. Janey, 1999 .

2. Reductive Amination

G. Huisman, A. Chadha, Jeffrey C. Moore, 2012 .

Chiral Salen ± Aluminum Complexes as Catalysts for Enantioselective Aldol Reactions of Aldehydes and 5-Alkoxyoxazoles : An Efficient Approach to the Asymmetric Synthesis of syn and anti b-Hydroxy-a-amino Acid Derivatives * *

J. Rebek, Davidr . Evans, J. Tedrow, 2001 .

Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic Reduction.

Feng Xu, Richard Desmond, F. Cabirol, 2018, Angewandte Chemie.

Development of a Diastereoselective Phosphorylation of a Complex Nucleoside via Dynamic Kinetic Resolution.

Martin D. Eastgate, J. Janey, G. Beutner, 2015, The Journal of organic chemistry.

Development of a Highly Automated Workflow for Investigating Polymorphism and Assessing Risk of Forming Undesired Crystal Forms within a Crystallization Design Space

J. Janey, Daniel Roberts, Jun Qiu, 2016 .

High-Throughput Automation in Chemical Process Development.

Jun Qiu, Jacob Janey, Jason M. Stevens, 2017, Annual review of chemical and biomolecular engineering.

Solubility Behaviors and Correlations of Common Organic Solvents

J. Janey, Jun Qiu, J. Albrecht, 2020 .

Uniting laboratory automation, DoE data, and modeling techniques to accelerate chemical process development

Jacob Janey, Jacob Albrecht, Victor W. Rosso, 2019, Reaction Chemistry & Engineering.

Development of A Sitagliptin Transaminase

J. Janey, 2013 .

Asymmetric, biocatalytic labeled compound synthesis using transaminases

S. Pollack, I. Davies, M. Truppo, 2012 .

Remote electronic control in the regioselective reduction of succinimides: a practical, scalable synthesis of Ep4 antagonist MF-310.

Yongxin Han, C. Raab, M. Palucki, 2009, The Journal of organic chemistry.

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Paul N. Devine, E. Mundorff, Sarena Tam, 2010, Science.

Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic Reduction.

F. Cabirol, J. Janey, Feng Xu, 2018, Angewandte Chemie.