Stuart Smith

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Structural and functional organization of the animal fatty acid synthase.

Andrzej Witkowski, A. Witkowski, A. Joshi, 2003, Progress in lipid research.

Coupling of the de Novo Fatty Acid Biosynthesis and Lipoylation Pathways in Mammalian Mitochondria*

Andrzej Witkowski, A. Witkowski, A. Joshi, 2007, Journal of Biological Chemistry.

Fatty acid synthesis in eukaryotes

H. Sul, Stuart Smith, 2008 .

Crystal structure of the Escherichia coli thioesterase II, a homolog of the human Nef binding enzyme

Zbigniew Dauter, Z. Dauter, Jia Li, 2000, Nature Structural Biology.

Mechanism and Substrate Recognition of Human Holo ACP Synthase

K. Kavanagh, U. Oppermann, Xiaoqiu Wu, 2007, Chemistry & biology.

Mechanism of chain length determination in biosynthesis of milk fatty acids.

Stuart Smith, 1980, Journal of dairy science.

Dibromopropanone Cross-linking of the Phosphopantetheine and Active-site Cysteine Thiols of the Animal Fatty Acid Synthase Can Occur Both Inter- and Intrasubunit

H. Witkowska, A. Falick, A. Witkowski, 1999, The Journal of Biological Chemistry.

Novel mutations in malonyl-CoA-acyl carrier protein transacylase provoke autosomal recessive optic neuropathy.

Jianping Ye, K. Yoshitake, T. Iwata, 2020, Human molecular genetics.

Identification of an Inverted CCAAT Box Motif in the Fatty-acid Synthase Gene as an Essential Element for Mediation of Transcriptional Regulation by cAMP (*)

B. Oskouian, Stuart Smith, V. Rangan, 1996, The Journal of Biological Chemistry.

Insulin acutely decreases hepatic fatty acid synthase activity.

Tiffany A. Miller, N. Beauchemin, S. Najjar, 2005, Cell metabolism.

Chapter 6 Fatty acid synthesis in eukaryotes

Stuart Smith, V. Rangan, 2002 .

Alteration of the Substrate Specificity of the Malonyl-CoA/Acetyl-CoA:Acyl Carrier ProteinS-Acyltransferase Domain of the Multifunctional Fatty Acid Synthase by Mutation of a Single Arginine Residue*

Stuart Smith, V. Rangan, 1997, The Journal of Biological Chemistry.

Engineering of an active animal fatty acid synthase dimer with only one competent subunit.

A. Witkowski, A. Joshi, Stuart Smith, 2003, Chemistry & biology.

Production of a Polyhydroxyalkanoate Biopolymer in Insect Cells with a Modified Eucaryotic Fatty Acid Synthase

D. Sherman, Mark D. Williams, J. A. Rahn, 1996, Applied and Environmental Microbiology.

Acyl specificity in glyceride synthesis by lactating rat mammary gland

S. Abraham, Stuart Smith, C. Lin, 1974, Lipids.

Biosynthesis of Fatty Acids by Lactating Human Breast Epithelial Cells: An Evaluation of the Contribution to the Overall Composition of Human Milk Fat

Stuart Smith, B. J. Thompson, 1985, Pediatric Research.

Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases.

K. Kavanagh, U. Oppermann, Xiaoqiu Wu, 2009, Chemistry & biology.

Conformational Flexibility of Metazoan Fatty Acid Synthase Enables Catalysis

Francisco J. Asturias, Edward J. Brignole, F. Asturias, 2008, Nature Structural &Molecular Biology.

The type I fatty acid and polyketide synthases: a tale of two megasynthases.

Shiou-Chuan Tsai, Stuart Smith, Stuart Smith, 2007, Natural product reports.

Head-to-head coiled arrangement of the subunits of the animal fatty acid synthase.

F. Asturias, H. Witkowska, A. Witkowski, 2004, Chemistry & biology.

Mechanism of the β-Ketoacyl Synthase Reaction Catalyzed by the Animal Fatty Acid Synthase†

A. Witkowski, Stuart Smith, A. Joshi, 2002 .

Mammalian ACSF3 Protein Is a Malonyl-CoA Synthetase That Supplies the Chain Extender Units for Mitochondrial Fatty Acid Synthesis*

A. Witkowski, Stuart Smith, Jennifer L. Thweatt, 2011, The Journal of Biological Chemistry.

Cloning, Expression, Characterization, and Interaction of Two Components of a Human Mitochondrial Fatty Acid Synthase

A. Joshi, Stuart Smith, Lei Zhang, 2003, Journal of Biological Chemistry.

Fatty Acid Synthase Dimers Containing Catalytically Active β-Ketoacyl Synthase or Malonyl/Acetyltransferase Domains in Only One Subunit Can Support Fatty Acid Synthesis at the Acyl Carrier Protein Domains of Both Subunits*

A. Joshi, Stuart Smith, V. Rangan, 1998, The Journal of Biological Chemistry.

Differential Affinity Labeling of the Two Subunits of the Homodimeric Animal Fatty Acid Synthase Allows Isolation of Heterodimers Consisting of Subunits That Have Been Independently Modified*

A. Joshi, Stuart Smith, V. Rangan, 1998, The Journal of Biological Chemistry.

The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

Stuart Smith, 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The effect of aromatic CoA esters on fatty acid synthetase: Biosynthesis of ω-phenyl fatty acids

Stuart Smith, A. Stern, 1983 .

Down-regulation of Mitochondrial Acyl Carrier Protein in Mammalian Cells Compromises Protein Lipoylation and Respiratory Complex I and Results in Cell Death*

A. Witkowski, Stuart Smith, D. Feng, 2009, Journal of Biological Chemistry.

The use of thioesterase II as a rat mammary epithelial cell-specific marker

S. Nandi, D. Pasco, Stuart Smith, 2004, Cell and Tissue Research.

Mechanism of Chain Length Determination in Biosynthesis of Milk Fatty Acids

Stuart Smith, 2009, Journal of Mammary Gland Biology and Neoplasia.

Structure and molecular organization of mammalian fatty acid synthase

James Z. Chadick, F. Asturias, A. Witkowski, 2005, Nature Structural &Molecular Biology.

The Human Thioesterase II Protein Binds to a Site on HIV-1 Nef Critical for CD4 Down-regulation*

D. Baltimore, G. B. Cohen, Stuart Smith, 2000, The Journal of Biological Chemistry.

Modification of mammalian fatty acid synthetase activity by NADP

T. Linn, Stuart Smith, S. Smith, 1985, FEBS letters.

Compromised Mitochondrial Fatty Acid Synthesis in Transgenic Mice Results in Defective Protein Lipoylation and Energy Disequilibrium

Y. Yoshinaga, S. Griffey, S. Young, 2012, PloS one.

Crystallization and preliminary diffraction studies of thioesterase II from rat mammary gland

R. Fletterick, A. Witkowski, Stuart Smith, 1995, Proteins.

Architectural Options for a Fatty Acid Synthase

Stuart Smith, Stuart Smith, 2006, Science.

Catalytic residues are shared between two pseudosubunits of the dehydratase domain of the animal fatty acid synthase.

A. Witkowski, A. Joshi, Stuart Smith, 2007, Chemistry & biology.

Characterization of the beta-carbon processing reactions of the mammalian cytosolic fatty acid synthase: role of the central core.

A. Witkowski, A. Joshi, Stuart Smith, 2004, Biochemistry.

Expression in Escherichia coli and Refolding of the Malonyl-/Acetyltransferase Domain of the Multifunctional Animal Fatty Acid Synthase*

Stuart Smith, V. Rangan, 1996, The Journal of Biological Chemistry.

The influence of pH on the partial reactions of the fatty acid synthetase multienzyme: Modification of product specificity

Stuart Smith, E. Agradi, 1976 .

Cloning, expression, and characterization of the human mitochondrial beta-ketoacyl synthase. Complementation of the yeast CEM1 knock-out strain.

A. Joshi, E. Schweizer, Stuart Smith, 2005, The Journal of biological chemistry.

Cloning, Expression, and Characterization of the Human Mitochondrial β-Ketoacyl Synthase

A. Joshi, E. Schweizer, Stuart Smith, 2005, Journal of Biological Chemistry.

Cloning, Expression, and Characterization of a Human 4′-Phosphopantetheinyl Transferase with Broad Substrate Specificity*

A. Joshi, Stuart Smith, Lei Zhang, 2003, Journal of Biological Chemistry.

The Type I Fatty Acid and Polyketide Synthases: A Tale of Two Megasynthases

Shiou-Chuan Tsai, Stuart Smith, Stuart Smith, 2008 .

Effect of modification of the length and flexibility of the acyl carrier protein-thioesterase interdomain linker on functionality of the animal fatty acid synthase.

A. Witkowski, A. Joshi, Stuart Smith, 2005, Biochemistry.

Assignment of the human ferrochelatase gene (FECH) and a locus for protoporphyria to chromosome 18q22.

N. Carter, D. Albertson, S. J. Smith, 1991, Genomics.

Expression in Escherichia coli, purification and characterization of two mammalian thioesterases involved in fatty acid synthesis.

J. Naggert, A. Witkowski, Stuart Smith, 1991, The Biochemical journal.

Mapping of functional interactions between domains of the animal fatty acid synthase by mutant complementation in vitro.

A. Witkowski, A. Joshi, Stuart Smith, 1997, Biochemistry.

Modular NRPSs are monomeric.

Stuart Smith, 2002, Chemistry & biology.

Cloning, sequencing, and characterization of Escherichia coli thioesterase II.

J. Naggert, H. Cho, J. Cronan, 1991, The Journal of biological chemistry.