Prahlad T. Ram

Gordon B Mills, Melissa Muller, Prahlad T. Ram, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma.

Kakajan Komurov, Gordon B Mills, Prahlad T. Ram, 2014, Cancer research.

Immunotherapy Targeting Folate Receptor Induces Cell Death Associated with Autophagy in Ovarian Cancer

Prahlad T. Ram, P. Ram, Ju-Seog Lee, 2014, Clinical Cancer Research.

Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors

Prahlad T. Ram, G. Brown, S. Hill, 1998, Molecular and Cellular Endocrinology.

Modulation of the Estrogen Response Pathway in Human Breast Cancer Cells by Melatonin

Prahlad T. Ram, P. Ram, S. Hill, 2001 .

The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB 2-positive breast cancer cells

Prahlad T. Ram, P. Ram, K. Komurov, 2012 .

Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer

Prahlad T. Ram, G. Mills, A. Børresen-Dale, 2015, Genome Medicine.

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism

Prahlad T. Ram, P. Ram, A. Maitra, 2016, eLife.

Adrenergic Stimulation of DUSP1 Impairs Chemotherapy Response in Ovarian Cancer

Prahlad T. Ram, P. Ram, A. Sood, 2015, Clinical Cancer Research.

G protein coupled receptor signaling through the Src and Stat3 pathway: role in proliferation and transformation

Ravi Iyengar, Prahlad T. Ram, Prahlad T Ram, 2001, Oncogene.

Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein.

Prahlad T. Ram, R. Iyengar, P. Ram, 2000, Science.

Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer

Prahlad T. Ram, P. Ram, A. Sood, 2014, Molecular systems biology.

A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease.

Prahlad T. Ram, P. Ram, I. Pipinos, 2014, Journal of hepatology.

Targeting KRas-dependent tumor growth, circulating tumor cells and metastasis in vivo by clinically significant miR-193a-3p

Prahlad T. Ram, G. Mills, P. Ram, 2016, Oncogene.

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth.

Prahlad T. Ram, P. Ram, A. Sood, 2016, Cell metabolism.

A Glucose G 6 P F 6 P GAP DHAP 3 PG Pyruvate Acetyl-CoA Citrate α-ketoglutarate Succinate Fumarate Malate OAA Aspartate Glutamate Glutamine PPP pathway Lactate

Prahlad T. Ram, P. Ram, A. Sood, 2016 .

Classification of High-Grade Serous Ovarian Cancer Using Tumor Morphologic Characteristics

Prahlad T. Ram, P. A. Futreal, Jun Yao, 2022, JAMA network open.

G Protein Pathways

Prahlad T. Ram, Susana R. Neves, R. Iyengar, 2002, Science.

Tumour angiogenesis regulation by the miR-200 family

George A Calin, Rehan Akbani, Prahlad T. Ram, 2013, Nature Communications.

GnRH-R–Targeted Lytic Peptide Sensitizes BRCA Wild-type Ovarian Cancer to PARP Inhibition

Prahlad T. Ram, P. Ram, A. Sood, 2019, Molecular Cancer Therapeutics.

An androgen-IL-6-Stat3 autocrine loop re-routes EGF signal in prostate cancer cells

Prahlad T. Ram, Susana R. Neves, R. Iyengar, 2007, Molecular and Cellular Endocrinology.

The ZNF304-integrin axis protects against anoikis in cancer

Prahlad T. Ram, K. Baggerly, P. Ram, 2015, Nature Communications.

CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance

Prahlad T. Ram, P. Ram, A. Sood, 2021, Cell reports.

Involvement of the mt1 melatonin receptor in human breast cancer.

Prahlad T. Ram, P. Ram, S. Hill, 2002, Cancer letters.

Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks

Prahlad T. Ram, G. Mills, P. Ram, 2015, Genome research.

Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.

Prahlad T. Ram, G. Mills, A. Børresen-Dale, 2014, Cancer cell.

A pan-cancer proteomic perspective on The Cancer Genome Atlas

Prahlad T. Ram, N. Städler, J. Weinstein, 2014, Nature Communications.

Hematogenous metastasis of ovarian cancer: rethinking mode of spread.

Prahlad T. Ram, P. Ram, Ju-Seog Lee, 2014, Cancer cell.

Melatonin inhibits estrogen receptor transactivation and cAMP levels in breast cancer cells

Prahlad T. Ram, P. Ram, S. Hill, 2004, Breast Cancer Research and Treatment.

Expression patterns of novel genes during mouse preimplantation embryogenesis

Prahlad T. Ram, P. Ram, R. Schultz, 1994, Molecular reproduction and development.

NetWalker: a contextual network analysis tool for functional genomics

Prahlad T. Ram, K. Komurov, Serkan Dursun, 2012, BMC Genomics.

NetWalker: a contextual network analysis tool for functional genomics

Prahlad T. Ram, S. Erdin, P. Ram, 2012, BMC Genomics.

Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens.

Prahlad T. Ram, K. Baggerly, P. Ram, 2017, JCI insight.

Amendment history : Expression of Concern ( June 2018 ) Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens

Prahlad T. Ram, K. Baggerly, Y. Wang, 2018 .

Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype

Prahlad T. Ram, P. Ram, A. Sood, 2021, Cell reports.

Regulation of gene expression in the mouse oocyte and early preimplantation embryo: developmental changes in Sp1 and TATA box-binding protein, TBP.

Prahlad T. Ram, P. Ram, R. Schultz, 1994, Development.

Reporter gene expression in G2 of the 1-cell mouse embryo.

Prahlad T. Ram, R. Schultz, P. T. Ram, 1993, Developmental biology.

Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer

Prahlad T. Ram, G. Mills, J. Gray, 2015, Oncogene.

Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis.

Yiling Lu, Gordon B Mills, Prahlad T. Ram, 2010, Cancer research.

Clinical Activity and Safety of Combination Therapy with Temsirolimus and Bevacizumab for Advanced Melanoma: A Phase II Trial (CTEP 7190/Mel47)

Prahlad T. Ram, P. Ram, G. Weiss, 2013, Clinical Cancer Research.

2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

Prahlad T. Ram, K. Baggerly, J. H. Kim, 2014, Nature Communications.

Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells.

Prahlad T. Ram, K. Komurov, S. Woodman, 2010, Cancer research.

Expression of Q227L-galphas in MCF-7 human breast cancer cells inhibits tumorigenesis.

Prahlad T. Ram, R. Iyengar, P. Ram, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Formation of Regulatory Patterns During Signal Propagation in a Mammalian Cellular Network

Prahlad T. Ram, Susana R. Neves, Sherry L. Jenkins, 2005, Science.

Molecular Analysis of Short- versus Long-Term Survivors of High-Grade Serous Ovarian Carcinoma

Prahlad T. Ram, K. Baggerly, B. Karlan, 2022, Cancers.

Melatonin synergizes with retinoic acid in the prevention and regression of breast cancer.

Prahlad T. Ram, S. Hill, D. Blask, 1999, Advances in experimental medicine and biology.

Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models

Prahlad T. Ram, P. Ram, A. Sood, 2021, Molecular Cancer Therapeutics.

Cancer Systems Biology: a peek into the future of patient care?

Prahlad T. Ram, G. Mills, H. M. Werner, 2014, Nature Reviews Clinical Oncology.

FABP4 as a key determinant of metastatic potential of ovarian cancer

Prahlad T. Ram, K. Baggerly, P. Ram, 2018, Nature Communications.

The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells

Tyler J Moss, Kakajan Komurov, Melissa Muller, 2012, Molecular systems biology.

Platelet-derived growth factor receptor alpha (PDGFRα) targeting and relevant biomarkers in ovarian carcinoma.

Prahlad T. Ram, P. Ram, K. Komurov, 2012, Gynecologic oncology.

Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death.

Prahlad T. Ram, K. Baggerly, P. Ram, 2011, Journal of the National Cancer Institute.

Silencing of p 130 Cas in Ovarian Carcinoma : A Novel Mechanism for Tumor Cell Death

Prahlad T. Ram, K. Baggerly, P. Ram, 2011 .

The Gαo/i-coupled Cannabinoid Receptor-mediated Neurite Outgrowth Involves Rap Regulation of Src and Stat3*

Prahlad T. Ram, R. Iyengar, P. Ram, 2005, Journal of Biological Chemistry.

Computational Approaches for Visualization and Integration of Omics Data

Prahlad T. Ram, P. Ram, V. Sehgal, 2014 .

Bioinformatics and systems biology

Prahlad T. Ram, G. Mills, J. Mendelsohn, 2012, Molecular oncology.

Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer.

Prahlad T. Ram, G. Mills, P. Ram, 2016, Cell reports.

Functional Proteomic Analysis of Signaling Networks and Response to Targeted Therapy

Prahlad T. Ram, P. Ram, 2007 .

Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4

Prahlad T. Ram, K. Baggerly, P. Ram, 2018, Molecular Cancer Therapeutics.

Next‐generation sequencing identifies high frequency of mutations in potentially clinically actionable genes in sebaceous carcinoma

Prahlad T. Ram, P. Ram, B. Czerniak, 2016, The Journal of pathology.