R. Dearman

发表

Examination of a vehicle for use with water soluble materials in the murine local lymph node assay.

I. Kimber, C. Ryan, L. Cruse, 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Immunogenicity of therapeutic proteins: Influence of aggregation

Ian Kimber, Jeremy P. Derrick, J. Derrick, 2013, Journal of immunotoxicology.

The Cutaneous Biochemical Redox Barrier: A Component of the Innate Immune Defenses against Sensitization by Highly Reactive Environmental Xenobiotics1

E. Healy, Pawan Kumar, I. Kimber, 2009, The Journal of Immunology.

Dendritic Cell IL-1α and IL-1β Are Polyubiquitinated and Degraded by the Proteasome*

G. López-Castejón, D. Brough, I. Kimber, 2014, The Journal of Biological Chemistry.

Compilation of Historical Local Lymph Node Data for Evaluation of Skin Sensitization Alternative Methods

Ian Kimber, David A. Basketter, Petra S. Kern, 2005, Dermatitis : contact, atopic, occupational, drug.

The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies

M. Wadhwa, R. Thorpe, J. Derrick, 2019, The Journal of Biological Chemistry.

Skin sensitization induced Langerhans’ cell mobilization: variable requirements for tumour necrosis factor‐α

R. Roberts, I. Kimber, R. Dearman, 2015, Immunology.

Epicutaneous exposure to proteins and skin immune function

D. Basketter, C. Griffiths, I. Kimber, 2014, European Journal of Dermatology.

The XS106 cell: a Langerhans’ cell surrogate with a selective type 2 phenotype

I. Kimber, R. Dearman, L. H. Eaton, 2014, Cutaneous and ocular toxicology.

Dendritic cells and the assessment in vitro of skin sensitizing potential

D. Basketter, I. Kimber, R. Dearman, 2013, Cutaneous and ocular toxicology.

Chemical allergy: translating biology into hazard characterization.

G Frank Gerberick, Ian Kimber, David A Basketter, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

Langerhans cell migration: not necessarily always at the center of the skin sensitization universe.

I. Kimber, R. Dearman, M. Cumberbatch, 2009, The Journal of investigative dermatology.

Dose metrics in the acquisition of skin sensitization: thresholds and importance of dose per unit area.

D. Basketter, I. Kimber, C. Ryan, 2008, Regulatory toxicology and pharmacology : RTP.

The Development of Novel Approaches to the Identification of Chemical and Protein Respiratory Allergens

Silvia Casati, David B. Warheit, Sue Gibbs, 2008, Alternatives to laboratory animals : ATLA.

Chemical Respiratory Allergy: Opportunities for Hazard Identification and Characterisation

Emanuela Corsini, Paul Cullinan, Raymond Agius, 2007, Alternatives to laboratory animals : ATLA.

Langerhans Cells and Skin Irritation

I. Kimber, R. Dearman, M. Cumberbatch, 2006 .

Recent Developments in Allergic Contact Dermatitis

I. Kimber, R. Dearman, 2005 .

Dendritic cells and skin sensitisation hazard assessment.

I. Kimber, R. Dearman, M. Cumberbatch, 2004, Toxicology in vitro : an international journal published in association with BIBRA.

Exogenous interleukin‐1β restores impaired Langerhans cell migration in aged skin

C. Griffiths, I. Kimber, R. Dearman, 2004, The British journal of dermatology.

Measurement of cytokine expression and Langerhans cell migration in human skin following suction blister formation

C. Griffiths, I. Kimber, R. Dearman, 2004, Experimental dermatology.

Cutaneous Cytokine Expression: Induction by Chemical Allergen and Paracrine Regulation

I. Kimber, R. Dearman, M. Cumberbatch, 2003 .

Assessment of glycosylation-dependent cell adhesion molecule 1 as a correlate of allergen-stimulated lymph node activation.

G. Orphanides, J. Moggs, I. Kimber, 2003, Toxicology.

Epidermal Langerhans cell migration and sensitisation to chemical allergens

C. Griffiths, I. Kimber, R. Dearman, 2003, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Influence of ageing on Langerhans cell migration in mice: identification of a putative deficiency of epidermal interleukin‐1β

I. Kimber, R. Dearman, M. Cumberbatch, 2002, Immunology.

Differential regulation of epidermal langerhans cell migration by interleukins (IL)-1alpha and IL-1beta during irritant- and allergen-induced cutaneous immune responses.

I. Kimber, R. Dearman, M. Cumberbatch, 2002, Toxicology and applied pharmacology.

Lactoferrin: influences on Langerhans cells, epidermal cytokines, and cutaneous inflammation.

C. Griffiths, D. Headon, I. Kimber, 2002, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Influence of sodium lauryl sulphate on 2,4-dinitrochlorobenzene-induced lymph node activation.

D. Basketter, I. Kimber, R. Scott, 1993, Toxicology.

Cytokine regulation of chemical sensitization.

I. Kimber, R. Dearman, M. R. Holliday, 1995, Toxicology letters.

Selective Stimulation of Cutaneous Interleukin 6 Expression by Skin Allergens

D. Basketter, E. Corsini, I. Kimber, 1996, Journal of applied toxicology : JAT.

Stimulation by oxazolone of increased IL-6, but not IL-10, in the skin of mice.

D. Basketter, I. Kimber, R. Dearman, 1996, Toxicology.

Constitutive and inducible expression of interleukin‐6 by Langerhans cells and lymph node dendritic cells

I. Kimber, R. Dearman, M. Cumberbatch, 1996, Immunology.

Interleukin 1β and the stimulation of Langerhans cell migration: comparisons with tumour necrosis factor α

I. Kimber, R. Dearman, M. Cumberbatch, 1997, Archives of Dermatological Research.

Differential induction of cutaneous TNF-alpha and IL-6 by topically applied chemicals.

D. Basketter, E. Corsini, S. Smith, 1997, American Journal of Contact Dermatitis.

Langerhans cells and chemical allergy.

I. Kimber, R. Dearman, M. Cumberbatch, 1998, Current opinion in immunology.

Production and in situ localization of cutaneous tumour necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) following skin sensitization.

M. Flint, S. Hotchkiss, I. Kimber, 1998, Cytokine.

Characteristics and regulation of the expression of interleukin 1 receptors by murine Langerhans cells and keratinocytes

I. Kimber, R. Dearman, M. Cumberbatch, 1998, Archives of Dermatological Research.

Induction by tumour necrosis factor α of dose-related changes in Langerhans cell frequency in mice

I. Kimber, R. Dearman, M. Cumberbatch, 1999, Archives of Dermatological Research.

Inhibition by dexamethasone of Langerhans cell migration: influence of epidermal cytokine signals.

I. Kimber, R. Dearman, M. Cumberbatch, 1999, Immunopharmacology.

Langerhans cell migration in mice requires intact type I interleukin 1 receptor (IL-1RI) function

I. Kimber, R. Dearman, M. Cumberbatch, 1999, Archives of Dermatological Research.

Evaluation of the Sensitizing Potential of Eugenol and Isoeugenol in Mice and Guinea Pigs

D. Basketter, I. Kimber, R. Dearman, 1996, Journal of applied toxicology : JAT.

The Hapten‐Atopy hypothesis II: the ‘cutaneous hapten paradox’

D. Basketter, J. Mcfadden, I. Kimber, 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Immune responses to contact allergens: novel approaches to hazard evaluation.

D. Basketter, I. Kimber, R. Dearman, 1999, Toxicology letters.

Adaptation of an ELISA assay for detection of IgG2a responses against therapeutic monoclonal antibodies in a mouse immunization model

J. Derrick, I. Kimber, R. Dearman, 2022, Journal of Immunotoxicology.

Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies

S. Uddin, J. Derrick, A. Pluen, 2019, Pharmaceutical Research.

Characterisation of immune responses to food allergens in mice

I. Kimber, R. Dearman, 2005, Proceedings of the Nutrition Society.

Assessment of protein allergenicity on the basis of immune reactivity: animal models.

R. Helm, B. Hammerberg, I. Kimber, 2002, Environmental health perspectives.

Immunotoxicological Aspects of Food Allergy

I. Kimber, R. Dearman, C. Betts, 2002 .

Food Allergy Safety Assessment: An Introduction

I. Kimber, R. Dearman, 2002 .

Respiratory allergenic potential of plant-derived proteins: Understanding the relationship between exposure and potency for risk assessments

I. Kimber, R. Dearman, G. Gerberick, 2015, Critical reviews in toxicology.

Dichloronitrobenzene: a reappraisal of its skin sensitization potential

D. Basketter, I. Kimber, R. Dearman, 1996, Contact dermatitis.

Dinitrohalobenzenes: evaluation of relative skin sensitization potential using the local lymph node assay

D. Basketter, I. Kimber, R. Dearman, 1997, Contact dermatitis.

The use of ethanol:diethylphthalate as a vehicle for the local lymph node assay

I. Kimber, R. Dearman, C. Betts, 2007, Contact dermatitis.

The impact of vehicle on assessment of relative skin sensitization potency of 1,4-dihydroquinone in the local lymph node assay.

D. Basketter, I. Kimber, R. Dearman, 1999, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Editor’s Highlight: Subvisible Aggregates of Immunogenic Proteins Promote a Th1-Type Response

M. Wadhwa, R. Thorpe, J. Derrick, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Cytokine fingerprinting and hazard assessment of chemical respiratory allergy

I. Kimber, R. Dearman, R. Dearman, 2001, Journal of applied toxicology : JAT.

Diisocyanates, occupational asthma and IgE antibody: implications for hazard characterization

D. Basketter, I. Kimber, R. Dearman, 2014, Journal of applied toxicology : JAT.

Differential stimulation of immune function by respiratory and contact chemical allergens.

I. Kimber, R. Dearman, 1991, Immunology.

Cytokine fingerprinting: characterization of chemical allergens.

I. Kimber, R. Dearman, 1999, Methods.

Allergen‐induced cytokine phenotypes in mice: role of CD4+ and CD8+ T cell populations

N. Humphreys, I. Kimber, R. Skinner, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Local lymph node assay: use in hazard and risk assessment

D. Basketter, I. Kimber, R. Dearman, 1999, Journal of applied toxicology : JAT.

Relationship between protein digestibility and allergenicity: comparisons of pepsin and cathepsin.

I. Kimber, R. Dearman, Emily S Foster, 2013, Toxicology.

Influence of protein expression system on elicitation of IgE antibody responses: experience with lactoferrin.

I. Kimber, R. Dearman, B. Flanagan, 2012, Toxicology.

Animal models of protein allergenicity: potential benefits, pitfalls and challenges

I. Kimber, R. Dearman, 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

A mouse model for food allergy using intraperitoneal sensitization.

I. Kimber, R. Dearman, 2007, Methods.

Influence of plant lipids on immune responses in mice to the major Brazil nut allergen Ber e 1

M. Alcocer, I. Kimber, R. Dearman, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

A multi-laboratory evaluation of a common in vitro pepsin digestion assay protocol used in assessing the safety of novel proteins

G. Bannon, G. Ladics, R. Goodman, 2004 .

Immunogenic properties of rapidly digested food proteins following gavage exposure of mice: a comparison of ovalbumin with a potato acid phosphatase preparation.

D. Basketter, I. Kimber, J. G. Kenna, 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Protein Allergenicity in Mice

I. Kimber, R. Dearman, K. Atherton, 2002, Annals of the New York Academy of Sciences.

Approaches to assessment of the allergenic potential of novel proteins in food from genetically modified crops.

I. Kimber, R. Dearman, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

Can animal models predict food allergenicity

I. Kimber, R. Dearman, 2001 .

Characterization of antibody responses induced in rodents by exposure to food proteins: influence of route of exposure.

D. Basketter, I. Kimber, R. Dearman, 2001, Toxicology.

Food allergy: what are the issues?

I. Kimber, R. Dearman, 2001, Toxicology letters.

FORUM Why Are Some Proteins Allergens

I. Kimber, R. Dearman, R. Huby, 2000 .

Divergent antibody isotype responses induced in mice by systemic exposure to proteins: a comparison of ovalbumin with bovine serum albumin.

D. Basketter, I. Kimber, R. Dearman, 2000, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Toxicology of protein allergenicity: prediction and characterization.

N. Kerkvliet, S. Taylor, I. Kimber, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

Interleukin-1β Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin

I. Kimber, R. Dearman, G. Gerberick, 2015, The Journal of Biological Chemistry.

Respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate in guinea pigs: comparison with trimellitic anhydride.

T. Landry, J. Pauluhn, P. Hext, 1999, Inhalation toxicology.

The impact of LLNA group size on the identification and potency classification of skin sensitizers: a review of published data

D. Basketter, I. Kimber, C. Ryan, 2009, Cutaneous and ocular toxicology.

Identification of B cell epitopes enhanced by protein unfolding and aggregation

L. Johannissen, J. Derrick, I. Kimber, 2019, Molecular immunology.

Influence of dibutyl phthalate on dermal sensitization to fluorescein isothiocyanate.

J. Heylings, I. Kimber, R. Dearman, 1996, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Factors affecting the development of food allergy

I. Kimber, R. Dearman, 2002, Proceedings of the Nutrition Society.

Local lymph node assay: validation assessment for regulatory purposes.

D. Basketter, I. Kimber, C. Ryan, 2000, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

What makes a chemical a respiratory sensitizer?

I. Kimber, R. Dearman, 2005, Current opinion in allergy and clinical immunology.

Designation of substances as skin sensitizing chemicals: a commentary

D. Basketter, I. Kimber, R. Dearman, 2003, Human & experimental toxicology.

Development of the local lymph node assay for risk assessment of chemicals and formulations

I. Kimber, R. Dearman, 2001 .

Differential effect of thalidomide and dexamethasone on the transcription factor NF-κB

J. Deighton, I. Kimber, R. Dearman, 2001 .

Cell and molecular biology of chemical allergy

I. Kimber, R. Dearman, 1997, Clinical reviews in allergy & immunology.

Detection of Allergen-Specific IgE Antibody Responses

I. Kimber, R. Dearman, P. Wachholz, 2005, Journal of immunotoxicology.

Albumin and calcium reference interval using healthy individuals and a data-mining approach

J. Barth, R. Dearman, S. Zouwail, 2020, Annals of clinical biochemistry.

The impact of the analytical performance specifications of calcium and albumin on adjusted calcium

J. Barth, R. Dearman, K. Hayden, 2020, Annals of clinical biochemistry.

Cytokine Responses Induced by Skin Exposure of Mice to Chemical Allergens: Role of Interleukin 12

I. Kimber, R. Dearman, 2004 .

Evaluation of 5-methylcytosine and 5-hydroxymethylcytosine as potential biomarkers for characterisation of chemical allergens.

J. Moggs, I. Kimber, R. Terranova, 2016, Toxicology.

The hapten–atopy hypothesis III: the potential role of airborne chemicals

D. Basketter, J. Mcfadden, I. Kimber, 2014, The British journal of dermatology.

Characterization of murine immune responses to allergenic diisocyanates.

I. Kimber, R. Dearman, L. Spence, 1992, Toxicology and applied pharmacology.

Differential immunogenicity and allergenicity of native and recombinant human lactoferrins: Role of glycosylation

A. Dell, A. Antonopoulos, S. Haslam, 2013, European journal of immunology.

Tumour necrosis factor-alpha-induced migration of human Langerhans cells: the influence of ageing.

C. Griffiths, I. Kimber, R. Dearman, 2002, The British journal of dermatology.

Intracellular Phosphotyrosine Induction by Major Histocompatibility Complex Class II Requires Co-aggregation with Membrane Rafts*

I. Kimber, R. Dearman, R. Huby, 1999, The Journal of Biological Chemistry.

The local lymph node assay: An interlaboratory evaluation of Interleukin 6 (IL‐6) production by draining lymph node cells

D. Basketter, I. Kimber, R. Dearman, 1994, Journal of applied toxicology : JAT.

Interleukin 6 production in vitro: An alternative read-out for the local lymph node assay.

I. Kimber, R. Dearman, J. Hilton, 1994, Toxicology in vitro : an international journal published in association with BIBRA.

Anti‐hapten antibodies in response to skin sensitization

I. Kimber, R. Dearman, N. Gellatly, 2016, Contact dermatitis.

Assessment of the allergenic potential of proteins.

I. Kimber, R. Dearman, C. Betts, 2003, Toxicology letters.

Characteristics of antibody responses induced in mice by protein allergens.

D. Basketter, I. Kimber, R. Dearman, 1997, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Inter‐laboratory comparisons of assessment of the allergenic potential of proteins in mice

D. Rouquié, B. Stahl, I. Kimber, 2009, Journal of applied toxicology : JAT.

Immunotoxicology and allergy: Opportunities for in vitro analysis.

I. Kimber, R. Dearman, Ian Kimber, 1991, Toxicology in vitro : an international journal published in association with BIBRA.

Functional Caspase-1 Is Required for Langerhans Cell Migration and Optimal Contact Sensitization in Mice1

I. Kimber, R. Dearman, M. Cumberbatch, 2001, The Journal of Immunology.

Contact Sensitization in Mice Langerhans Cell Migration and Optimal Functional Caspase-1 Is Required for

I. Kimber, R. Dearman, M. Cumberbatch, 2001 .

Immunoregulation of skin sensitization and regulatory T cells

I. Kimber, M. Travis, Stefan F Martin, 2012, Contact dermatitis.

Langerhans cells require signals from both tumour necrosis factor alpha and interleukin 1 beta for migration.

I. Kimber, R. Dearman, M. Cumberbatch, 1997, Advances in experimental medicine and biology.

The Local Lymph Node Assay (LLNA)

C. Rovida, D. Basketter, I. Kimber, 2012, Current protocols in toxicology.

Contribution of CD4+ and CD8+ T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergens

D. Kemeny, I. Kimber, R. Dearman, 1996, Immunology.

Characterization of chemical allergens as a function of divergent cytokine secretion profiles induced in mice.

D. Basketter, I. Kimber, R. Dearman, 1996, Toxicology and applied pharmacology.

Characterization in mice of the immunological properties of five allergenic acid anhydrides

I. Humphreys, I. Kimber, R. Dearman, 2000, Journal of applied toxicology : JAT.

Chemical respiratory allergy, IgE and the relevance of predictive test methods: a commentary

I. Kimber, R. Dearman, E. V. Warbrick, 1998, Human & experimental toxicology.

Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides

I. Humphreys, I. Kimber, R. Dearman, 2002, Journal of applied toxicology : JAT.

Cytokine profiling of chemical allergens in mice: impact of mitogen on selectivity of response

I. Kimber, R. Dearman, C. Betts, 2009, Journal of applied toxicology : JAT.

Cytokine profiling of chemical allergens in mice: measurement of message versus protein.

I. Kimber, R. Dearman, C. Betts, 2008, Toxicology.

The Use of Cytokines in the Identification and Characterization of Chemical Allergens

I. Kimber, R. Dearman, 2007 .

Methods for the identiﬁcation of chemical respiratory allergens in rodents: comparisons of cytokine proﬁling with induced changes in serum IgE

N. Humphreys, I. Kimber, R. Skinner, 2003, Journal of applied toxicology : JAT.

Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses.

I. Kimber, R. Skinner, R. Dearman, 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Impaired Langerhans cell migration in psoriasis is due to an altered keratinocyte phenotype induced by interleukin‐17

C. Griffiths, I. Kimber, R. Dearman, 2018, The British journal of dermatology.

Chemical allergy in humans: Fresh perspectives

D. Basketter, J. Thyssen, I. Kimber, 2014, Journal of immunotoxicology.

Chemical allergen induced perturbations of the mouse lymph node DNA methylome.

J. Moggs, I. Kimber, R. Terranova, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Chemical respiratory allergy: role of IgE antibody and relevance of route of exposure.

I. Kimber, R. Dearman, 2002, Toxicology.

Selective induction of type 2 cytokines following topical exposure of mice to platinum salts.

D. Basketter, I. Kimber, R. Dearman, 1998, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Impaired Langerhans cell migration in psoriasis

H. Young, C. Griffiths, I. Kimber, 2006, The Journal of experimental medicine.

C. Griffiths, I. Kimber, R. Dearman, 2013, The Journal of investigative dermatology.

Adhesion molecule expression by epidermal Langerhans cells and lymph node dendritic cells: a comparison

I. Kimber, R. Dearman, M. Cumberbatch, 1996, Archives of Dermatological Research.

Temporal changes in cytokine gene expression profiles induced in mice by trimellitic anhydride.

I. Kimber, R. Dearman, C. Betts, 2002, Toxicology letters.

Inducible interleukin 4 (IL-4) production and mRNA expression following exposure of mice to chemical allergens.

I. Kimber, F. Gerberick, C. Ryan, 1998, Toxicology letters.

Peanut sensitisation and allergy: influence of early life exposure to peanuts

J. Buttriss, J. Strid, Rachel L. Thompson, 2010, British Journal of Nutrition.

The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses.

S. Durham, M. Larché, M. Shamji, 2006, Journal of immunological methods.

Interleukin‐17 and interleukin‐23 regulate Langerhans cell migration

C. Griffiths, I. Kimber, R. Dearman, 2016, The British journal of dermatology.

Allergic contact dermatitis: the cellular effectors

I. Kimber, R. Dearman, 2002, Contact dermatitis.

Di-(2-ethylhexyl) phthalate is without adjuvant effect in mice on ovalbumin.

I. Kimber, R. Dearman, C. Betts, 2008, Toxicology.

Differential ability of occupational chemical contact and respiratory allergens to cause immediate and delayed dermal hypersensitivity reactions in mice.

D. Basketter, I. Kimber, R. Dearman, 1992, International archives of allergy and immunology.

Cytokine Production by CD4+ and CD8+ T Cells in Mice following Primary Exposure to Chemical Allergens: Evidence for Functional Differentiation of T Lymphocytes in vivo

D. Kemeny, I. Kimber, R. Dearman, 1998, International Archives of Allergy and Immunology.

T lymphocyte dynamics in methylisothiazolinone‐allergic patients

I. Kimber, R. Dearman, N. Gellatly, 2016, Contact dermatitis.

FORUM Toxicology of Protein Allergenicity: Prediction and Characterization

Steve L. Taylor, N. Kerkvliet, I. Kimber, 1999 .

Predictive testing for respiratory sensitization in the mouse.

D. Basketter, I. Kimber, R. Dearman, 1996, Toxicology letters.

Experimental assessment of the sensitizing properties of formaldehyde.

D. Basketter, I. Kimber, R. Dearman, 1996, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Identification of Chemical Respiratory Allergens: Dose-Response Relationships in the Mouse IgE Test

D. Basketter, I. Kimber, R. Dearman, 1995 .

Serological responses induced in mice by immunogenic proteins and by protein respiratory allergens.

D. Basketter, I. Kimber, R. Dearman, 1994, Toxicology letters.

The mechanisms and evaluation of chemically induced allergy.

I. Kimber, R. Dearman, 1992, Toxicology letters.

Langerhans cells, antigen presentation, and the diversity of responses to chemical allergens.

S. Gould, D. Basketter, I. Kimber, 1992, The Journal of investigative dermatology.

The cellular and molecular basis for divergent allergic responses to chemicals.

D. Basketter, I. Kimber, R. Dearman, 1992, Chemico-biological interactions.

Accessory cell requirements for T lymphocyte activation and interferon-gamma production in peripheral lymph nodes.

I. Kimber, R. Dearman, A. Morris, 1996, Immunology letters.

Cytokine-mast cell interactions: relevance to IgE-mediated chemical allergy.

I. Kimber, R. Dearman, J. Coleman, 1994, Toxicology.

Induction of respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate (MDI) in guinea pigs. Influence of route of exposure.

P. Botham, P. Hext, I. Kimber, 1994, Toxicology.

The effects of arginine glutamate, a promising excipient for protein formulation, on cell viability: Comparisons with NaCl

C. F. van der Walle, S. Uddin, A. Golovanov, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Phenotypic variation in mast cell responsiveness to the inhibitory action of nitric oxide

I. Kimber, R. Dearman, J. Coleman, 2000, Inflammation Research.

The reduced local lymph node assay: the impact of group size

G. Patlewicz, D. Basketter, I. Kimber, 2008, Journal of applied toxicology : JAT.

Chemical respiratory sensitizers: Activity in a non-standard local lymph node assay (LLNA)

D. Basketter, I. Kimber, R. Dearman, 2007 .

The lymphocyte transformation test in allergic contact dermatitis: New opportunities

I. Kimber, R. Dearman, N. Gellatly, 2016, Journal of immunotoxicology.

Guinea Pig, Mouse, and Rat Models for Safety Assessment of Protein Allergenicity

I. Kimber, R. Dearman, K. Sarlo, 2005 .

Analysis of interleukin 12 protein production and mRNA expression in mice exposed topically to chemical allergens.

D. Basketter, I. Kimber, R. Dearman, 1999, Toxicology.

Antigen-specific and nonspecific determinants of cytokine production during topical sensitization of mice to chemical allergens.

D. Kemeny, I. Kimber, R. Dearman, 2000, The Journal of allergy and clinical immunology.

Epidermal cytokines and the induction of allergic and non-allergic contact dermatitis.

I. Kimber, R. Dearman, M. Cumberbatch, 1997, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

Cytokine profiling and chemical allergy.

I. Kimber, R. Dearman, 2002, Toxicology and applied pharmacology.

IgG and IgE antibody responses following exposure of Brown Norway rats to trimellitic anhydride: comparison of inhalation and topical exposure.

I. Kimber, R. Dearman, E. V. Warbrick, 2002, Toxicology.

THE MOUSE IgE TEST: INTERLABORATORY EVALUATION AND COMPARISON OF BALB/c AND C57BL/6 STRAIN MICE

D. Basketter, G. Ladics, I. Kimber, 1998 .

Examination of Phenotypic Changes in Peripheral Blood‐Derived Dendritic Cells Following Exposure to a Contact Allergen: Cell Surface Marker and Gene Expression

I. Kimber, C. Ryan, R. Dearman, 2005 .

A multi-laboratory evaluation of a common in vitro pepsin digestion assay protocol used in assessing the safety of novel proteins.

R. Van Ree, G. Bannon, G. Ladics, 2003, Regulatory toxicology and pharmacology : RTP.

Mechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity.

J. Ashby, I. Kimber, R. Dearman, 1993, Environmental health perspectives.

Allergic Contact Dermatitis

G Frank Gerberick, Ian Kimber, David A Basketter, 1998, Springer Berlin Heidelberg.

Tartrate resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature

F. Rieux-Laucat, J. Casanova, S. Lovell, 2010, Nature Genetics.

Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals.

G Frank Gerberick, Ian Kimber, I. Kimber, 2007, Methods.

Contact allergenic potency: correlation of human and local lymph node assay data.

I Kimber, G F Gerberick, R J Dearman, 2001, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Skin sensitization potency of methyl methacrylate in the local lymph node assay: comparisons with guinea‐pig data and human experience

Ian Kimber, David A Basketter, D. Basketter, 2006, Contact dermatitis.

This information is current as Environmental Xenobiotics against Sensitization by Highly Reactive DefensesA Component of the Innate Immune The Cutaneous Biochemical Redox Barrier : and

E. Healy, Pawan Kumar, I. Kimber, 2009 .

Use of a B cell marker (B220) to discriminate between allergens and irritants in the local lymph node assay.

G Frank Gerberick, Ian Kimber, I. Kimber, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

Alternative approaches to the identification and characterization of chemical allergens.

I Kimber, R J Dearman, D A Basketter, 2001, Toxicology in vitro : an international journal published in association with BIBRA.

Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization.

Petra S Kern, Grace Patlewicz, David W Roberts, 2007, Chemical research in toxicology.

IL‐18 is a key proximal mediator of contact hypersensitivity and allergen‐induced Langerhans cell migration in murine epidermis

Ian Kimber, I. Kimber, R. Dearman, 2008, Journal of leukocyte biology.

Sensitization to 2,4-dinitrochlorobenzene: influence of vehicle on absorption and lymph node activation.

J. Heylings, I. Kimber, R. Dearman, 1996, Toxicology.

Predictive identification of human skin sensitization thresholds

Frank Gerberick, Ian Kimber, Bob Safford, 2005, Contact dermatitis.

Potency and risk assessment of a skin‐sensitizing disperse dye using the local lymph node assay

I. Kimber, R. Dearman, C. Betts, 2005, Contact dermatitis.

The local lymph node assay: developments and applications.

I Kimber, R J Dearman, D A Basketter, 1994, Toxicology.

Identification of metal allergens in the local lymph node assay.

I Kimber, G F Gerberick, R J Dearman, 1999, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Local Lymph Node Assays

Ian Kimber, I. Kimber, R. Dearman, 2004, Current protocols in toxicology.

Human potency predictions for aldehydes using the local lymph node assay

I Kimber, G F Gerberick, R J Dearman, 2001, Contact dermatitis.

Threshold for classification as a skin sensitizer in the local lymph node assay: a statistical evaluation.

I Kimber, R J Dearman, D A Basketter, 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

An international evaluation of the murine local lymph node assay and comparison of modified procedures.

J Hilton, I Kimber, G F Gerberick, 1995, Toxicology.

The direct peptide reactivity assay: selectivity of chemical respiratory allergens.

A. M. Api, I. Kimber, R. Dearman, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Comparative analysis of skin sensitization potency of acrylates (methyl acrylate, ethyl acrylate, butyl acrylate, and ethylhexyl acrylate) using the local lymph node assay

Ian Kimber, Karin Wiench, K. Wiench, 2007, Contact dermatitis.

Induction of IgE antibody responses by protein allergens: inter-laboratory comparisons.

E. Debruyne, I. Kimber, R. Skinner, 2003, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Proteomic and Bioinformatic Analyses for the Identification of Proteins With Low Allergenic Potential for Hazard Assessment.

Nora L. Krutz, S. Maurer-Stroh, I. Kimber, 2019, Toxicological sciences : an official journal of the Society of Toxicology.

Evaluation of an in vitro method for the measurement of specific IgE antibody responses: the rat basophilic leukemia (RBL) cell assay.

I. Kimber, R. Skinner, R. Dearman, 2005, Toxicology.

Intradermal exposure of BALB/c strain mice to peanut protein elicits a type 2 cytokine response.

I. Kimber, R. Dearman, C. Betts, 2004, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Evaluation of protein allergenic potential in mice: dose–response analyses

I Kimber, R J Dearman, D A Basketter, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Assessment of the inherent allergenic potential of proteins in mice.

I. Kimber, R. Dearman, S. Stone, 2003, Environmental health perspectives.

Protein Allergenicity: Mouse Models

D. Basketter, I. Kimber, R. Dearman, 2002 .

Peanut lectin elicits a Th2 cytokine gene expression and protein secretion profile in mice

I. Kimber, R. Dearman, C. Betts, 2002 .

An assessment of the ability of phthalates to influence immune and allergic responses.

I. Kimber, R. Dearman, 2010, Toxicology.

Characterization of the allergenic potential of proteins: an assessment of the kiwifruit allergen actinidin

I. Kimber, R. Dearman, S. McClain, 2014, Journal of applied toxicology : JAT.

Regulation of allergic responses to chemicals and drugs: possible roles of epigenetic mechanisms.

J. Moggs, I. Kimber, R. Terranova, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Chemical respiratory allergy: reverse engineering an adverse outcome pathway.

Darrell R Boverhof, Ian Kimber, David A Basketter, 2014, Toxicology.

Chemical reactivity measurements: potential for characterization of respiratory chemical allergens.

G Frank Gerberick, Anne Marie Api, Jon F Lalko, 2011, Toxicology in vitro : an international journal published in association with BIBRA.

Identification of gene expression changes induced by chemical allergens in dendritic cells: opportunities for skin sensitization testing.

G Frank Gerberick, Ian Kimber, I. Kimber, 2006, The Journal of investigative dermatology.

Interactions of contact allergens with dendritic cells: opportunities and challenges for the development of novel approaches to hazard assessment.

G Frank Gerberick, Ian Kimber, I. Kimber, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen.

G Frank Gerberick, Ian Kimber, I. Kimber, 2004, Toxicology letters.

Determination of protein allergenicity: studies in mice.

I Kimber, R J Dearman, I. Kimber, 2001, Toxicology letters.

Immune Responses: Adverse Versus Non-Adverse Effects

I. Kimber, R. Dearman, 2002, Toxicologic pathology.

Why are some proteins allergens?

I Kimber, R J Dearman, I. Kimber, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses

I Kimber, R J Dearman, D A Basketter, 1999, Journal of applied toxicology : JAT.

The selective peptide reactivity of chemical respiratory allergens under competitive and non-competitive conditions

A. M. Api, I. Kimber, R. Dearman, 2013, Journal of immunotoxicology.

Reactivity of chemical respiratory allergens in the Peroxidase Peptide Reactivity Assay.

I Kimber, A M Api, G F Gerberick, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

Use of the local lymph node assay for the estimation of relative contact allergenic potency

I. Kimber, D. Basketter, P. Evans, 2000, Contact dermatitis.

Influence of application vehicle on skin sensitization to methylchloroisothiazolinone/methylisothiazolinone: an analysis using the local lymph node assay

D. Basketter, I. Kimber, R. Dearman, 1999, Contact dermatitis.

Human neutrophil antigens: Nature, clinical significance and detection

R. Dearman, A. Poles, T. Browne, 2020, International journal of immunogenetics.

A re-appraisal of the skin-sensitizing activity of 2,4-dinitrothiocyanobenzene.

D. Basketter, I. Kimber, R. Dearman, 1997, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Allergic contact dermatitis: a commentary on the relationship between T lymphocytes and skin sensitising potency.

Gavin Maxwell, Ian Kimber, I. Kimber, 2012, Toxicology.

Interactions of IFN-gamma with IL-3 and IL-4 in the regulation of serotonin and arachidonate release from mouse peritoneal mast cells.

I. Kimber, R. Dearman, J. Coleman, 1994, Immunology.

“Omics” Technologies and the Immune System

R. Luebke, G. Ladics, N. Kaminski, 2006, Toxicology mechanisms and methods.

Extra domain A-positive fibronectin-positive feedback loops and their association with cutaneous inflammatory disease.

D. Basketter, I. Kimber, R. Dearman, 2011, Clinics in dermatology.

Danger, intracellular signaling, and the orchestration of dendritic cell function in skin sensitization

I. Kimber, R. Dearman, Joseph S. Ainscough, 2013, Journal of immunotoxicology.

Factors influencing the induction phase of skin sensitization.

Ian Kimber, I. Kimber, R. Dearman, 2003, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

What makes a chemical an allergen?

Ian Kimber, I. Kimber, R. Dearman, 2003, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Lower levels of interleukin‐1β gene expression are associated with impaired Langerhans’ cell migration in aged human skin

C. Griffiths, I. Kimber, R. Dearman, 2017, Immunology.

Migration of interleukin-6 producing Langerhans cells to draining lymph nodes following skin sensitization.

S. Hopkins, I. Kimber, J. Hope, 1995, Advances in Experimental Medicine and Biology.

The local lymph node assay: past, present and future

Ian Kimber, D. Basketter, I. Kimber, 2002, Contact dermatitis.

Local lymph node assay responses to paraphenylenediamine: intra‐ and inter‐laboratory evaluations

I. Kimber, D. Basketter, I. Kimber, 1999, Journal of applied toxicology : JAT.

Temporal stability of local lymph node assay responses to hexyl cinnamic aldehyde

Ian Kimber, D. Basketter, P. Evans, 1998, Journal of applied toxicology : JAT.

Impact of Cutaneous IL-10 on Resident Epidermal Langerhans’ Cells and the Development of Polarized Immune Responses

Ian Kimber, I. Kimber, Kirsty Clelland, 2005, The Journal of Immunology.

Differential effects of UVA1 and UVB radiation on Langerhans cell migration in mice.

M. Norval, I. Kimber, R. Dearman, 2000, Journal of photochemistry and photobiology. B, Biology.

Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells.

B. K. Park, D. Naisbitt, N. Humphreys, 2005, Toxicology.

Cytokine endpoints for the local lymph node assay: consideration of interferon‐γ and interleukin 12

I. Kimber, D. Basketter, I. Kimber, 1999, Journal of applied toxicology : JAT.

Surrogate CD16‐expressing effector cell lines for determining the bioactivity of therapeutic monoclonal antibodies

M. Wadhwa, R. Thorpe, J. Derrick, 2017, Journal of pharmaceutical and biomedical analysis.

Chemical allergy: considerations for the practical application of cytokine profiling.

Neil Humphreys, Ian Kimber, David A Basketter, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Approaches to the identification and classification of chemical allergens in mice.

I. Kimber, R. Dearman, 1993, Journal of pharmacological and toxicological methods.

T lymphocyte phenotype of contact‐allergic patients: experience with nickel and p‐phenylenediamine

J. P. Gosling, C. Stretton, I. Kimber, 2019, Contact dermatitis.

Selective Haptenation of Cellular or Extracellular Protein by Chemical Allergens: Association with Cytokine Polarization

N. Kitteringham, B. K. Park, D. Naisbitt, 2005 .

The Aryl Hydrocarbon Receptor: Differential Contribution to T Helper 17 and T Cytotoxic 17 Cell Development

Andrew G Smith, I. Kimber, R. Dearman, 2014, PloS one.

Investigation of lymph node cell proliferation as a possible immunological correlate of contact sensitizing potential.

I Kimber, R J Dearman, I. Kimber, 1991, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Stimulation of Langerhans cell migration in mice by tumour necrosis factor alpha and interleukin 1 beta.

I. Kimber, R. Dearman, M. Cumberbatch, 1997, Advances in experimental medicine and biology.

Chemical allergens--what are the issues?

D. Basketter, I. Kimber, R. Dearman, 2010, Toxicology.

Differential cytokine production following chronic exposure of mice to chemical respiratory and contact allergens.

D. Basketter, I. Kimber, R. Dearman, 1995, Immunology.

Inhalation Exposure to Methylene Chloride Does Not Induce Systemic Immunotoxicity in Rats

I. Kimber, P. Dugard, R. Dearman, 2003, Journal of toxicology and environmental health. Part A.

Toll‐like receptor ligand activation of murine bone marrow‐derived dendritic cells

Gavin Maxwell, Ian Kimber, D. Basketter, 2009, Immunology.

Investigating Liquid-Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl.

Shahid Uddin, C. F. van der Walle, S. Uddin, 2017, Molecular pharmaceutics.

The effect of arginine glutamate on the stability of monoclonal antibodies in solution

Malgorzata B. Tracka, Shahid Uddin, Alexander P. Golovanov, 2014, International journal of pharmaceutics.

Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody.

I. Kimber, R. Dearman, J. M. Hegarty, 1991, International archives of allergy and applied immunology.

The effect of different analytical platforms and methods on the performance of population-specific adjusted calcium equation

J. Barth, R. Dearman, S. Zouwail, 2020, Annals of clinical biochemistry.

Local lymph node assay: validation assessment for regulatory purposes.

I Kimber, G F Gerberick, R J Dearman, 2000, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

The clonal structure and dynamics of the human T cell response to an organic chemical hapten

B. Chain, K. Wicks, R. Dearman, 2021, eLife.

Synergistic effects of chemical insult and toll-like receptor ligands on dendritic cell activation.

D. Basketter, I. Kimber, R. Dearman, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Langerhans cell mobilization distinguishes between early-onset and late-onset psoriasis.

C. Griffiths, I. Kimber, C. E. Kleyn, 2010, The Journal of investigative dermatology.

Selective haptenation of cellular or extracellular protein by chemical allergens: association with cytokine polarization.

N. Kitteringham, B. K. Park, D. Naisbitt, 2005, Chemical research in toxicology.

Influence of topical exposure to chemical allergens on murine Langerhans cells. Comparison of 2,4-dinitrochlorobenzene with trimellitic anhydride.

S. Gould, D. Basketter, I. Kimber, 1992, Journal of clinical & laboratory immunology.

Identification of dendritic cells as a major source of interleukin-6 in draining lymph nodes following skin sensitization of mice.

S. Hopkins, I. Kimber, J. Hope, 1995, Immunology.

The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors

K. Best, B. Chain, J. Heather, 2017, Front. Immunol..

Influence of Escherichia coli chaperone DnaK on protein immunogenicity

M. Wadhwa, R. Thorpe, J. Derrick, 2016, Immunology.

Estimation of relative skin sensitizing potency using the local lymph node assay: a comparison of formaldehyde with glutaraldehyde.

D. Basketter, P. Evans, I. Kimber, 1998, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Toxicology of Chemical Respiratory Hypersensitivity

I. Kimber, R. Dearman, 1997 .

Inducible interleukin-4-secreting cells provoked in mice during chemical sensitization.

D. Basketter, I. Kimber, R. Dearman, 1994, Immunology.

Interleukin 1 beta and the stimulation of Langerhans cell migration: comparisons with tumour necrosis factor alpha.

I. Kimber, R. Dearman, M. Cumberbatch, 1997, Archives of dermatological research.

Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies

S. Uddin, J. Derrick, A. Pluen, 2019, Pharmaceutical Research.

Local lymph node assay - validation, conduct and use in practice.

R J Fielder, I Kimber, G F Gerberick, 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The kinetics of cytokine production by draining lymph node cells following primary exposure of mice to chemical allergens.

S. Hopkins, I. Kimber, J. Hope, 1994, Immunology.

Inhalation exposure to respiratory sensitising chemicals down-regulates guinea pig IgE and pulmonary responses.

P. Botham, R. Dearman, 1990, International archives of allergy and applied immunology.

Characterization of skin sensitizing chemicals: A lesson learnt from nickel allergy

Ian Kimber, David A Basketter, D. Basketter, 2011, Journal of immunotoxicology.

Interleukin 6 (IL-6) Production by Lymph Node Cells: An Alternative Endpoint for the Murine Local Lymph Node Assay

Ian Kimber, S. Hopkins, I. Kimber, 1993 .

The local lymph node assay in practice: a current regulatory perspective

I Kimber, G F Gerberick, R J Dearman, 2006, Human & experimental toxicology.

The local lymph node assay and skin sensitization: a cut‐down screen to reduce animal requirements?

Petra S Kern, G Frank Gerberick, Ian Kimber, 2006, Contact dermatitis.

Failure of vehicle to influence local lymph node assay response to benzocaine.

I Kimber, R J Dearman, D A Basketter, 2000, Contact dermatitis.

IL-1beta-induced Langerhans' cell migration and TNF-alpha production in human skin: regulation by lactoferrin.

C. Griffiths, I. Kimber, R. Dearman, 2003, Clinical and experimental immunology.

Allergen‐induced changes in interleukin 1β (iL‐1β) mRNA expression by human blood‐derived dendritic cells: inter‐individual differences and relevance for sensitization testing

I Kimber, R J Dearman, D A Basketter, 2001, Journal of applied toxicology : JAT.

Transcript Profiling of T Lymphocytes and Dendritic Cells in a Co–culture System Using Anti‐CD3 and Allergen Activation

I. Kimber, C. Ryan, R. Dearman, 2004 .

A chemical dataset for evaluation of alternative approaches to skin‐sensitization testing

Ian Kimber, G. Patlewicz, D. Basketter, 2004, Contact dermatitis.

P2X7R activation drives distinct IL-1 responses in dendritic cells compared to macrophages

D. Brough, A. Verkhratsky, Pavlos C. Englezou, 2015, Cytokine.

Variable effects of chemical allergens on serum ige concentration in mice. Preliminary evaluation of a novel approach to the identification of respiratory sensitizers

D. Basketter, I. Kimber, R. Dearman, 1992, Journal of applied toxicology : JAT.

Extrapolating Local Lymph Node Assay EC3 Values To Estimate Relative Sensitizing Potency

Ian Kimber, David A. Basketter, Petra S. Kern, 2007, Cutaneous and ocular toxicology.

Induced changes in total serum IgE concentration in the Brown Norway rat: potential for identification of chemical respiratory allergens

I. Kimber, R. Dearman, R. Dearman, 2002, Journal of applied toxicology : JAT.

Characterization in mice of the immunological properties of five allergenic acid anhydrides

I. Humphreys, I. Kimber, R. Dearman, 2000, Journal of applied toxicology : JAT.

A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses

D. Basketter, I. Kimber, R. Dearman, 1999, Journal of applied toxicology : JAT.

Cytokine endpoints for the local lymph node assay: consideration of interferon‐γ and interleukin 12

D. Basketter, I. Kimber, R. Dearman, 1999, Journal of applied toxicology : JAT.

Classification of Chemical Allergens According to Cytokine Secretion Profiles of Murine Lymph Node Cells

D. Basketter, S. Smith, I. Kimber, 1997, Journal of applied toxicology : JAT.

Cutaneous immunopathology of long‐standing complex regional pain syndrome

R. Moots, S. Edwards, A. Goebel, 2015, European journal of pain.

Dermal Sensitization Quantitative Risk Assessment for Fragrance Ingredients

D. Basketter, C. Cowan-Ellsberry, C. Ryan, 2011 .

REVIEWCytokines and chemokines in the initiation and regulation of epidermal Langerhans cell mobilization

I. Kimber, R. Dearman, M. Cumberbatch, 2000, The British journal of dermatology.

Selectivity of IgE responses, mast cell sensitization, and cytokine expression in the immune response of Brown Norway rats to chemical allergens.

D. Basketter, I. Kimber, R. Dearman, 1996, Cellular immunology.

Tumour necrosis factor‐α‐induced migration of human Langerhans cells: the influence of ageing

I. Kimber, R. Dearman, M. Cumberbatch, 2002 .

Langerhans cells require signals from both tumour necrosis factor‐α and interleukin‐1β for migration

I. Kimber, R. Dearman, M. Cumberbatch, 1997, Immunology.

Activity of human contact allergens in the murine local lymph node assay

I Kimber, G F Gerberick, R J Dearman, 2000, Contact dermatitis.

Preliminary assessment of the skin sensitizing activity of selected rodent carcinogens using the local lymph node assay.

I Kimber, R J Dearman, J Ashby, 2001, Toxicology.

Streptozotocin: inherent but not expressed skin sensitizing activity

J. Ashby, I. Kimber, R. Dearman, 1995, Contact dermatitis.

Investigation of induced changes in interleukin 1beta mRNA expression by cultured human dendritic cells as an in vitro approach to skin sensitization testing.

I Kimber, D A Basketter, Dearman, 2000, Toxicology in vitro : an international journal published in association with BIBRA.

Toxic shock syndrome: characterization of human immune responses to TSST-1 and evidence for sensitivity thresholds.

R. Goering, M. Kotb, J. Parsonnet, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

The suitability of hexyl cinnamic aldehyde as a calibrant for the murine local lymph node assay

Ian Kimber, D. Basketter, I. Kimber, 2001, Contact dermatitis.

No impairment of monocyte-derived Langerhans cell phenotype or function in early-onset psoriasis

C. Griffiths, I. Kimber, R. Dearman, 2012, Clinical and experimental dermatology.

Keratinocytes derived from late‐onset‐psoriasis skin do not impair Langerhans cell migration

C. Griffiths, I. Kimber, R. Dearman, 2018, The British journal of dermatology.

Butyl benzyl phthalate: effects on immune responses to ovalbumin in mice

I. Kimber, R. Dearman, C. Betts, 2009, Journal of applied toxicology : JAT.

Reciprocal effects of interleukin‐4 and interferon‐γ on immunoglobulin E‐mediated mast cell degranulation: a role for nitric oxide but not peroxynitrite or cyclic guanosine monophosphate

Kimber, Dearman, D. Basketter, 1999, Immunology.

The lymphocyte transformation test in allergic contact dermatitis: New opportunities

I. Kimber, R. Dearman, N. Gellatly, 2016, Journal of immunotoxicology.

Danger, intracellular signaling, and the orchestration of dendritic cell function in skin sensitization

I. Kimber, R. Dearman, Joseph S. Ainscough, 2013, Journal of immunotoxicology.

The effect of ageing on phenotype and function of monocyte-derived Langerhans cells

C. Griffiths, I. Kimber, C. Griffiths, 2011, The British journal of dermatology.

The effects of acute social stress on epidermal Langerhans' cell frequency and expression of cutaneous neuropeptides.

H. Richards, C. Griffiths, I. Kimber, 2008, The Journal of investigative dermatology.

Cytokines and Langerhans cell mobilisation in mouse and man.

C. Griffiths, I. Kimber, R. Dearman, 2005, Cytokine.

The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma

R. Djukanović, S. Holgate, D. Davies, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Role of CD4+ T helper 2‐type cells in cutaneous inflammatory responses induced by fluorescein isothiocyanate

I. Kimber, R. Dearman, R. Dearman, 2000, Immunology.

Lack of association between interleukin-6 production by contact allergen-activated draining lymph node cells and lymphoproliferative activity.

M. Norval, I. Kimber, R. Dearman, 1998, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Antigen-induced unresponsiveness in contact sensitivity: association of depressed T lymphocyte proliferative responses with decreased interleukin 6 secretion.

S. Hopkins, I. Kimber, J. Hope, 1996, Immunology letters.

Interleukin (IL)‐18 induces Langerhans cell migration by a tumour necrosis factor‐α‐ and IL‐1β‐dependent mechanism

I. Kimber, I. Kimber, R. Dearman, 2001, Immunology.

Chemical allergen induced perturbations of the mouse lymph node DNA methylome.

J. Moggs, I. Kimber, R. Terranova, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Tumour necrosis factor‐α induces Langerhans cell migration in humans

Griffiths, Kimber, Dearman, 1999, The British journal of dermatology.

Dose metrics in the acquisition of skin sensitization: thresholds and importance of dose per unit area.

A. M. Api, D. Basketter, I. Kimber, 2008, Regulatory toxicology and pharmacology : RTP.

IL‐1β‐induced Langerhans’ cell migration and TNF‐α production in human skin: regulation by lactoferrin

I. Kimber, R. Dearman, M. Cumberbatch, 2003 .

Why does allergic contact dermatitis exist?

D. Basketter, J. Mcfadden, I. Kimber, 2013, The British journal of dermatology.

Langerhans cell migration

I. Kimber, R. Dearman, M. Cumberbatch, 2000, Clinical and experimental dermatology.

Assessment of the skin sensitization potential of topical medicaments using the local lymph node assay: an interlaboratory evaluation.

J Hilton, I Kimber, G F Gerberick, 1998, Journal of toxicology and environmental health. Part A.

Differential regulation by thalidomide and dexamethasone of cytokine expression in human peripheral blood mononuclear cells.

J. Deighton, I. Kimber, R. Dearman, 1998, Immunopharmacology.

Further evaluation of the local lymph node assay in the final phase of an international collaborative trial.

J Hilton, I Kimber, G F Gerberick, 1996, Toxicology.

Divergent immune responses to respiratory and contact chemical allergens: antibody elicited by phthalic anhydride and oxazolone

I. Kimber, R. Dearman, R. Dearman, 1992, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Selective down-regulation of T cell- and non-T cell-derived tumour necrosis factor alpha by thalidomide: comparisons with dexamethasone.

J. Deighton, I. Kimber, R. Dearman, 1999, Immunology letters.

Allergic contact dermatitis: a commentary on the relationship between T lymphocytes and skin sensitising potency.

I. Kimber, R. Dearman, Stefan F. Martin, 2012, Toxicology.

The Mouse IgE Test for the Identification of Potential Chemical Respiratory Allergens: Considerations of Stability and Controls

D. Basketter, I. Kimber, R. Dearman, 1996, Journal of applied toxicology : JAT.

Inactivation of p53 gene in human and murine osteosarcoma cells.

N. Chandar, J. Novák, B. Billig, 1992, British Journal of Cancer.

Exogenous topical lactoferrin inhibits allergen‐induced Langerhans cell migration and cutaneous inflammation in humans

D. Headon, I. Kimber, R. Dearman, 2001, The British journal of dermatology.

Regulation of epidermal Langerhans cell migration by lactoferrin

O. Conneely, D. Headon, I. Kimber, 2000, Immunology.

In vivo assays of langerhans cell migration.

I. Kimber, R. Dearman, M. Cumberbatch, 2001, Methods in molecular medicine.

Respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate in guinea pigs: comparison with trimellitic anhydride.

J. Pauluhn, P. Hext, J. Doe, 1999, Inhalation toxicology.

Immunologic basis for autoimmunity and the potential influences of xenobiotics.

I. Kimber, R. Dearman, 2002, Toxicology letters.