J. Mouton

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Comparison of Spectrophotometric and Visual Readings of NCCLS Method and Evaluation of a Colorimetric Method Based on Reduction of a Soluble Tetrazolium Salt, 2,3-Bis {2-Methoxy-4-Nitro-5-[(Sulfenylamino) Carbonyl]-2H- Tetrazolium-Hydroxide}, for Antifungal Susceptibility Testing of AspergillusSpeci

P. J. Donnelly, J. Meis, P. Verweij, 2001, Journal of Clinical Microbiology.

In Vitro Drug Interaction Modeling of Combinations of Azoles with Terbinafine against Clinical Scedosporium prolificans Isolates

Paul E. Verweij, J. Meis, P. Verweij, 2003, Antimicrobial Agents and Chemotherapy.

In vitro susceptibilities of zygomycetes to conventional and new antifungals.

J. Meis, P. Verweij, E. Dannaoui, 2003, The Journal of antimicrobial chemotherapy.

Assessing in vitro combinations of antifungal drugs against yeasts and filamentous fungi: comparison of different drug interaction models.

J. Meis, P. Verweij, J. Meletiadis, 2005, Medical mycology.

Optimizing the Design and Analysis of Clinical Trials for Antibacterials Against Multidrug-resistant Organisms: A White Paper From COMBACTE’s STAT-Net

Leonhard Held, Stephan Harbarth, Stavros Nikolakopoulos, 2018, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Use of old antibiotics now and in the future from a pharmacokinetic/pharmacodynamic perspective.

U. Theuretzbacher, J. Mouton, A. Muller, 2015, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Highly variable absorption of clavulanic acid during the day: a population pharmacokinetic analysis

T. van Gelder, B. D. de Winter, J. Mouton, 2018, The Journal of antimicrobial chemotherapy.

Drug Clearance by Continuous Haemodiafiltration

M. Vos, J. Mouton, H. H. Vincent, 1994 .

Antibiotics in the prevention of neonatal group B streptococcal infections: the evidence

E. Steegers, R. Voskuyl, J. Mouton, 2009 .

TLR1, TLR2, and TLR6 gene polymorphisms are associated with increased susceptibility to complicated skin and skin structure infections.

M. Oosting, L. Joosten, M. Netea, 2014, The Journal of infectious diseases.

Pharmacokinetics of Clindamycin in Pregnant Women in the Peripartum Period

J. DeJongh, M. Danhof, E. Steegers, 2010, Antimicrobial Agents and Chemotherapy.

The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women.

M. Danhof, E. Steegers, R. Voskuyl, 2008, British journal of clinical pharmacology.

Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes.

J. DeJongh, M. Danhof, R. Voskuyl, 2008, American journal of obstetrics and gynecology.

moxicillin pharmacokinetics in pregnant women ith preterm premature rupture of the membranes

J. DeJongh, R. Voskuyl, J. Mouton, 2007 .

A Long Journey from Minimum Inhibitory Concentration Testing to Clinically Predictive Breakpoints: Deterministic and Probabilistic Approaches in Deriving Breakpoints

P. Ambrose, J. Mouton, A. Dalhoff, 2009, Infection.

Applying Pharmacodynamics for Susceptibility Breakpoint Selection and Susceptibility Testing

W. Craig, G. Kahlmeter, P. Ambrose, 2007 .

Pharmacokinetics of Penicillin G in Infants with a Gestational Age of Less than 32 Weeks

J. DeJongh, M. Danhof, J. N. van den Anker, 2007, Antimicrobial Agents and Chemotherapy.

P1370 Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks

J. DeJongh, M. Danhof, W. Goessens, 2007 .

Correlation of the MIC and Dose/MIC Ratio of Fluconazole to the Therapeutic Response of Patients with Mucosal Candidiasis and Candidemia

J. Donnelly, M. Cuenca‐Estrella, J. Rodríguez-Tudela, 2007, Antimicrobial Agents and Chemotherapy.

Impact of Pharmacodynamics on Dosing Schedules: Optimizing Efficacy, Reducing Resistance, and Detection of Emergence of Resistance

J. Mouton, 2005 .

Impact of pharmacodynamics on breakpoint selection for susceptibility testing.

J. Mouton, 2003, Infectious disease clinics of North America.

Black Yeasts and Their Filamentous Relatives: Principles of Pathogenesis and Host Defense

M. Netea, S. Seyedmousavi, W. Melchers, 2014, Clinical Microbiology Reviews.

Real-time monitoring of hydrogen cyanide (HCN) and ammonia (NH3) emitted by Pseudomonas aeruginosa

Julien Mandon, Johan W Mouton, Anne H Neerincx, 2015, Journal of breath research.

Identification of Pseudomonas aeruginosa and Aspergillus fumigatus mono- and co-cultures based on volatile biomarker combinations

Jeroen J. Jansen, B. Geurts, L. Buydens, 2016, Journal of breath research.

Comparison of Pharmacodynamics of Azithromycin and Erythromycin In Vitro and In Vivo

H. Verbrugh, K. Fuursted, J. Mouton, 1998, Antimicrobial Agents and Chemotherapy.

Extended-spectrum β-lactamase (ESBL) polymerase chain reaction assay on rectal swabs and enrichment broth for detection of ESBL carriage.

A. Buiting, J. Verweij, J. Mouton, 2018, The Journal of hospital infection.

Pharmacodynamics of Ceftolozane Combined with Tazobactam against Enterobacteriaceae in a Neutropenic Mouse Thigh Model

J. Mouton, M. Melchers, E. Mavridou, 2016, Antimicrobial Agents and Chemotherapy.

In Vitro Activity of Ceftolozane Alone and in Combination with Tazobactam against Extended-Spectrum-β-Lactamase-Harboring Enterobacteriaceae

J. Mouton, M. Melchers, A. C. van Mil, 2015, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and Penetration of Ceftazidime and Avibactam into Epithelial Lining Fluid in Thigh- and Lung-Infected Mice

S. Seyedmousavi, J. Mouton, W. Nichols, 2015, Antimicrobial Agents and Chemotherapy.

Pharmacodynamics of Ceftazidime and Avibactam in Neutropenic Mice with Thigh or Lung Infection

S. Seyedmousavi, Virna J. A. Schuck, J. Mouton, 2015, Antimicrobial Agents and Chemotherapy.

Pharmacodynamics of Imipenem in Combination with β-Lactamase Inhibitor MK7655 in a Murine Thigh Model

M. Motyl, J. Mouton, E. Mangin, 2014, Antimicrobial Agents and Chemotherapy.

Assessment of efficacy of antifungals in experimental models of invasive aspergillosis in an era of emerging resistance: the value of real-time quantitative PCR.

S. Seyedmousavi, W. Melchers, P. Verweij, 2011, Current opinion in pharmacology.

Isavuconazole, a broad-spectrum triazole for the treatment of systemic fungal diseases

S. Seyedmousavi, P. Verweij, J. Mouton, 2015, Expert review of anti-infective therapy.

Concentration-dependency of beta-lactam-induced filament formation in Gram-negative bacteria.

J. V. D. van der Meer, A. Dofferhoff, J. Mouton, 2008, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Inhaled antibiotics: dry or wet?

H. Tiddens, H. Janssens, S. Devadason, 2014, European Respiratory Journal.

In Vitro Activities of New and Conventional Antifungal Agents against Clinical Scedosporium Isolates

J. Meis, J. Donnelly, P. Verweij, 2002, Antimicrobial Agents and Chemotherapy.

Impact of bacterial load on pharmacodynamics and susceptibility breakpoints for tigecycline and Klebsiella pneumoniae

G. Daikos, A. Tsakris, J. Meletiadis, 2017, The Journal of antimicrobial chemotherapy.

Tissue concentrations: do we ever learn?

O. Cars, W. Craig, P. Tulkens, 2007, The Journal of antimicrobial chemotherapy.

Rapid and reliable real-time PCR assay for detection of the macrolide efflux gene and subsequent discrimination between its distinct subclasses mef(A) and mef(E).

J. Mouton, C. Klaassen, Debby M Klomberg, 2005, Journal of microbiological methods.

Molecular Detection of the Macrolide Efflux Gene: To Discriminate or Not To Discriminate between mef(A) and mef(E)

J. Mouton, C. Klaassen, 2005, Antimicrobial Agents and Chemotherapy.

Bacterial quantification in tissue homogenates from in vivo pharmacodynamic studies using growth curves.

S. Pournaras, J. Meletiadis, J. Mouton, 2020, Journal of medical microbiology.

Polymyxin Susceptibility Testing and Breakpoint Setting.

K. Sei, J. Turnidge, J. Mouton, 2019, Advances in experimental medicine and biology.

Variation of MIC measurements: the contribution of strain and laboratory variability to measurement precision

J. Turnidge, A. Voss, J. Meletiadis, 2018, The Journal of antimicrobial chemotherapy.

Resistance mechanisms and drug susceptibility testing of nontuberculous mycobacteria.

D. van Soolingen, M. Boeree, J. Mouton, 2012, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Therapeutic Drug Monitoring of Voriconazole

J. Donnelly, R. Aarnoutse, A. Warris, 2008, Therapeutic drug monitoring.

Diagnostic and medical needs for therapeutic drug monitoring of antibiotics

A. van Belkum, D. Nicolau, J. Roberts, 2019, European Journal of Clinical Microbiology & Infectious Diseases.

Pharmacokinetic/Pharmacodynamic Modelling of Antibacterials In Vitro and In Vivo Using Bacterial Growth and Kill Kinetics

Johan W Mouton, Alexander A Vinks, A. Vinks, 2005, Clinical pharmacokinetics.

Optimizing dosing of nitrofurantoin from a PK/PD point of view: What do we need to know?

J. Mouton, A. Muller, R. Wijma, 2019, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Soup with or without meatballs: Impact of nutritional factors on the MIC, kill‐rates and growth‐rates

J. Mouton, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

MIC-based dose adjustment: facts and fables

J. Turnidge, G. Kahlmeter, R. Cantón, 2018, The Journal of antimicrobial chemotherapy.

Pharmacodynamics of fosfomycin against ESBL- and/or carbapenemase-producing Enterobacteriaceae

J. Meletiadis, J. Mouton, M. Melchers, 2017, The Journal of antimicrobial chemotherapy.

Pharmacodynamics of nitrofurantoin at different pH levels against pathogens involved in urinary tract infections

J. Meletiadis, J. Mouton, M. Melchers, 2017, The Journal of antimicrobial chemotherapy.

Patient-specific modelling of regional tobramycin concentration levels in airways of patients with cystic fibrosis: can we dose once daily?

E. Andrinopoulou, H. Tiddens, H. Janssens, 2017, The Journal of antimicrobial chemotherapy.

Pharmacodynamics and differential activity of nitrofurantoin against ESBL-positive pathogens involved in urinary tract infections.

J. Meletiadis, J. Mouton, M. Melchers, 2016, The Journal of antimicrobial chemotherapy.

General Concepts of Pharmacodynamics for Anti-infective Agents

J. Mouton, 2016 .

Continuous Infusion of Beta-lactam Antibiotics

J. Mouton, A. Muller, 2014 .

Relationship between pharmacodynamic indices and killing patterns in vitro.

J. Mouton, 2011, Future microbiology.

Effect of Treatment Duration on Pharmacokinetic/Pharmacodynamic Indices Correlating with Therapeutic Efficacy of Ceftazidime in Experimental Klebsiella pneumoniae Lung Infection

M. T. ten Kate, I. Bakker-Woudenberg, W. Goessens, 2006, Antimicrobial Agents and Chemotherapy.

Relationship Between Minimum Inhibitory Concentration and Stationary Concentration Revisited

A. Vinks, J. Mouton, 2005, Clinical pharmacokinetics.

Alteration of postantibiotic effect during one dosing interval of tobramycin, simulated in an in vitro pharmacokinetic model

H. Verbrugh, J. Mouton, J. D. den Hollander, 1996, Antimicrobial agents and chemotherapy.

Population Pharmacokinetics of Imipenem in Critically Ill Patients: A Parametric and Nonparametric Model Converge on CKD-EPI Estimated Glomerular Filtration Rate as an Impactful Covariate

W. Yamada, M. Neely, T. van Gelder, 2020, Clinical Pharmacokinetics.

Clinical applications of population pharmacokinetic models of antibiotics: Challenges and perspectives

T. van Gelder, B. D. de Winter, J. Mouton, 2018, Pharmacological research.

The development and implementation of a guideline-based clinical decision support system to improve empirical antibiotic prescribing

H. Sijs, J. Mouton, D. Melles, 2022, BMC Medical Informatics and Decision Making.

Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis.

C. Hertogh, M. Hulscher, B. Kullberg, 2016, The Lancet. Infectious diseases.

The pharmacokinetics and pharmacodynamics of pulmonary Mycobacterium avium complex disease treatment.

C. Daley, L. Heifets, M. Boeree, 2012, American journal of respiratory and critical care medicine.

The stability of antimycobacterial drugs in media used for drug susceptibility testing.

R. Aarnoutse, J. Mouton, J. van Ingen, 2018, Diagnostic microbiology and infectious disease.

Failure of the Amikacin, Cefoxitin, and Clarithromycin Combination Regimen for Treating Pulmonary Mycobacterium abscessus Infection

D. van Soolingen, D. Deshpande, J. Pasipanodya, 2016, Antimicrobial Agents and Chemotherapy.

Moxifloxacin's Limited Efficacy in the Hollow-Fiber Model of Mycobacterium abscessus Disease

D. van Soolingen, D. Deshpande, J. Pasipanodya, 2016, Antimicrobial Agents and Chemotherapy.

Amikacin Pharmacokinetics/Pharmacodynamics in a Novel Hollow-Fiber Mycobacterium abscessus Disease Model

D. van Soolingen, D. Deshpande, J. Pasipanodya, 2015, Antimicrobial Agents and Chemotherapy.

Time-kill kinetics of antibiotics active against rapidly growing mycobacteria.

D. van Soolingen, J. Mouton, J. van Ingen, 2015, The Journal of antimicrobial chemotherapy.

Time-kill kinetics of slowly growing mycobacteria common in pulmonary disease.

D. van Soolingen, J. Mouton, J. van Ingen, 2015, The Journal of antimicrobial chemotherapy.

Clofazimine Prevents the Regrowth of Mycobacterium abscessus and Mycobacterium avium Type Strains Exposed to Amikacin and Clarithromycin

D. van Soolingen, A. D. de Jong, J. Meletiadis, 2015, Antimicrobial Agents and Chemotherapy.

Synergistic activity of rifampicin and ethambutol against slow-growing nontuberculous mycobacteria is currently of questionable clinical significance.

D. van Soolingen, W. Hoefsloot, M. Boeree, 2013, International journal of antimicrobial agents.

Nitrofurantoin's efficacy and safety as prophylaxis for urinary tract infections: a systematic review of the literature and meta-analysis of controlled trials.

S. Harbarth, A. Huttner, J. Mouton, 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

The Effect of Antibiotic Restriction Programs on Prevalence of Antimicrobial Resistance: A Systematic Review and Meta-Analysis

A. Boyd, J. Prins, J. Mouton, 2021, Open forum infectious diseases.

Trends, seasonality and the association between outpatient antibiotic use and antimicrobial resistance among urinary bacteria in the Netherlands.

A. Troelstra, A. Buiting, J. van Rosmalen, 2020, The Journal of antimicrobial chemotherapy.

Consumption of antimicrobial agents and antimicrobial resistance among medically important bacteria in The Netherlands in 2015 : NethMap 2016

S. Natsch, D. Mevius, J. Mouton, 2016 .

Effect of pH on the In Vitro Activities of Amphotericin B, Itraconazole, and Flucytosine against Aspergillus Isolates

J. Meis, P. Verweij, J. Mouton, 2004, Antimicrobial Agents and Chemotherapy.

The role of pharmacokinetics/pharmacodynamics in setting clinical MIC breakpoints: the EUCAST approach.

A. MacGowan, M. Steinbakk, A. Rodloff, 2012, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Pharmacokinetics of colistin in patients with multidrug-resistant Gram-negative infections: A pilot study

S. Kaur, N. Shafiq, P. Ray, 2018, The Indian journal of medical research.

Comparative Study of the Effects of Ceftizoxime, Piperacillin, and Piperacillin-Tazobactam Concentrations on Antibacterial Activity and Selection of Antibiotic-Resistant Mutants of Enterobacter cloacae and Bacteroides fragilis In Vitro and In Vivo in Mixed-Infection Abscesses

I. Gyssens, W. Goessens, J. Mouton, 2004, Antimicrobial Agents and Chemotherapy.

Activity of Cefepime in Combination with the Novel β-Lactamase Inhibitor Taniborbactam (VNRX-5133) against Extended-Spectrum-β-Lactamase-Producing Isolates in In Vitro Checkerboard Assays

Wendy Kloezen, J. Meletiadis, J. Mouton, 2021, Antimicrobial Agents and Chemotherapy.

Oral Fosfomycin Efficacy with Variable Urinary Exposures following Single and Multiple Doses against Enterobacterales: the Importance of Heteroresistance for Growth Outcome

A. Peleg, J. Roberts, J. Meletiadis, 2020, Antimicrobial Agents and Chemotherapy.

Oral Fosfomycin Treatment for Enterococcal Urinary Tract Infections in a Dynamic In Vitro Model

A. Peleg, J. Roberts, J. Meletiadis, 2020, Antimicrobial Agents and Chemotherapy.

Amplification of Antimicrobial Resistance in Gut Flora of Patients Treated with Ceftriaxone

E. Tacconelli, J. Meletiadis, J. Mouton, 2017, Antimicrobial Agents and Chemotherapy.

Tigecycline Is Highly Efficacious against Mycobacterium abscessus Pulmonary Disease

D. van Soolingen, D. Deshpande, J. Pasipanodya, 2016, Antimicrobial Agents and Chemotherapy.

Omadacycline as a promising new agent for the treatment of infections with Mycobacterium abscessus

H. Bax, J. D. de Steenwinkel, J. Mouton, 2019, The Journal of antimicrobial chemotherapy.

Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex isolates - The EUCAST broth microdilution reference method for MIC determination.

G. Lina, G. Kahlmeter, D. Cirillo, 2020, Clinical Microbiology and Infection.

Multicentre testing of the EUCAST broth microdilution reference method for MIC determination on Mycobacterium tuberculosis.

Thomas Bo Schön, G. Lina, G. Kahlmeter, 2020, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Effect of Manganese in Test Media on In Vitro Susceptibility of Enterobacteriaceae and Acinetobacter baumannii to Tigecycline

J. Kluytmans, P. V. van Keulen, C. Verhulst, 2012, Journal of Clinical Microbiology.

A Prospective Clinical Study Characterizing the Influence of Morbid Obesity on the Pharmacokinetics of Gentamicin: Towards Individualized Dosing in Obese Patients

E. Hazebroek, C. Knibbe, J. Mouton, 2019, Clinical Pharmacokinetics.

Population Pharmacokinetic Analysis of Nonlinear Behavior of Piperacillin during Intermittent or Continuous Infusion in Patients with Cystic Fibrosis

R. Jelliffe, A. Vinks, J. Mouton, 2003, Antimicrobial Agents and Chemotherapy.

Population pharmacokinetics of ceftazidime in cystic fibrosis patients analyzed by using a nonparametric algorithm and optimal sampling strategy

M. Danhof, A. Vinks, D. Touw, 1996, Antimicrobial agents and chemotherapy.

High interindividual variability in urinary fosfomycin concentrations in healthy female volunteers.

T. van Gelder, J. Mouton, B. Koch, 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol

L. Leibovici, Y. Carmeli, O. Zusman, 2016, BMJ Open.

Forgotten antibiotics: an inventory in Europe, the United States, Canada, and Australia.

J. Turnidge, K. Bush, W. Craig, 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Tobramycin Clearance Is Best Described by Renal Function Estimates in Obese and Non-obese Individuals: Results of a Prospective Rich Sampling Pharmacokinetic Study

M. Wiezer, C. Knibbe, J. Mouton, 2019, Pharmaceutical Research.

Assessment of Bactericidal Drug Activity and Treatment Outcome in a Mouse Tuberculosis Model Using a Clinical Beijing Strain

H. Bax, G. J. de Knegt, J. D. de Steenwinkel, 2017, Antimicrobial Agents and Chemotherapy.

Optimal exposures of ceftazidime predict the probability of microbiological and clinical outcome in the treatment of nosocomial pneumonia.

J. Mouton, A. Muller, N. Punt, 2013, The Journal of antimicrobial chemotherapy.

Pharmacokinetics and Dosing of Ceftobiprole Medocaril for the Treatment of Hospital- and Community-Acquired Pneumonia in Different Patient Populations

A. Torres, F. Pea, J. Mouton, 2016, Clinical Pharmacokinetics.

Successful treatment of azole-resistant invasive aspergillosis in a bottlenose dolphin with high-dose posaconazole

S. Seyedmousavi, W. Melchers, S. Gans, 2017, Medical Mycology Case Reports.

Study protocol for an international, multicentre stepped-wedge cluster randomised trial to evaluate the impact of a digital antimicrobial stewardship smartphone application

G. Catho, S. Teerenstra, J. Conly, 2020, BMJ Open.

International Society of Anti-infective Pharmacology

J. Mouton, 2002 .

Antibiotic treatment in cystic fibrosis. Part 2: dose optimization.

A. Vinks, D. Touw, J. Mouton, 2000 .

The Association Between Empirical Antibiotic Treatment and Mortality in Severe Infections Caused by Carbapenem-resistant Gram-negative Bacteria: A Prospective Study

L. Leibovici, Y. Carmeli, O. Zusman, 2018, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Amplified Fragment Length Polymorphism Fingerprinting Is an Effective Technique To Distinguish Streptococcus pneumoniae from Other Streptococci and an Efficient Alternative to Pulsed-Field Gel Electrophoresis for Molecular Typing of Pneumococci

J. Mouton, C. Klaassen, C. Neeleman, 2004, Journal of Clinical Microbiology.

European Committee on Antimicrobial Susceptibility Testing (EUCAST) Technical Notes on antimicrobial susceptibility testing.

A. MacGowan, I. Odenholt, M. Steinbakk, 2006, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Polymorphisms in cytokine genes IL6, TNF, IL10, IL17A and IFNG influence susceptibility to complicated skin and skin structure infections

M. Oosting, M. Netea, I. Gyssens, 2014, European Journal of Clinical Microbiology & Infectious Diseases.

Pharmacokinetics of Amoxicillin in Maternal, Umbilical Cord, and Neonatal Sera

J. DeJongh, M. Danhof, E. Steegers, 2009, Antimicrobial Agents and Chemotherapy.

Evaluation of dosing regimen on amoxicillin exposure in pregnant women with preterm premature rupture of the membranes using Monte Carlo Simulation.

M. Danhof, R. Voskuyl, J. Mouton, 2009 .

Chapter 7 Pharmacokinetics of amoxicillin in maternal , umbilical cord and neonatal serum

J. DeJongh, M. Danhof, E. Steegers, 2009 .

Chapter 6 Clavulanic acid does not influence amoxicillin pharmacokinetics in pregnant women during labor

J. DeJongh, M. Danhof, E. Steegers, 2009 .

In-vitro susceptibility and molecular characterisation of macrolide resistance mechanisms among Streptococcus pneumonia isolates in The Netherlands: the DUEL 2 study.

S. Meijers, J. Mouton, C. Klaassen, 2005, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Pharmacodynamics of Isavuconazole in an Aspergillus fumigatus Mouse Infection Model

S. Seyedmousavi, W. Melchers, J. Meis, 2015, Antimicrobial Agents and Chemotherapy.

Posaconazole Prophylaxis in Experimental Azole-Resistant Invasive Pulmonary Aspergillosis

S. Seyedmousavi, W. Melchers, P. Verweij, 2014, Antimicrobial Agents and Chemotherapy.

Intrapulmonary Posaconazole Penetration at the Infection Site in an Immunosuppressed Murine Model of Invasive Pulmonary Aspergillosis Receiving Oral Prophylactic Regimens

S. Seyedmousavi, W. Melchers, P. Verweij, 2014, Antimicrobial Agents and Chemotherapy.

Influence of pulmonary surfactant on in vitro bactericidal activities of amoxicillin, ceftazidime, and tobramycin

D. Gommers, J. Kluytmans, J. Mouton, 1995, Antimicrobial agents and chemotherapy.

Correlation of MIC value and disk inhibition zone diameters in clinical Legionella pneumophila serogroup 1 isolates.

B. Diederen, J. Mouton, J. D. den Boer, 2013, Diagnostic microbiology and infectious disease.

Human Host Defense and Cytokines in Mycobacterial Infectious Diseases : Interleukin-18 Cannot Compensate for Genetic Defects in the Interleukin-12 System

J. Mouton, 2010 .

Why the AUC/MIC ratio should not be used to predict the effects of β-lactams

J. Mouton, 2002 .

Nasal carriage of Staphylococcus aureus as a major risk factor for wound infections after cardiac surgery.

H. Verbrugh, C. Vandenbroucke-Grauls, J. Kluytmans, 1995, The Journal of infectious diseases.

Pneumolysin Is a Key Factor in Misidentification of Macrolide-Resistant Streptococcus pneumoniae and Is a Putative Virulence Factor of S. mitis and Other Streptococci

J. Mouton, C. Klaassen, C. Neeleman, 2004, Journal of Clinical Microbiology.

The role of azoles in the management of azole-resistant aspergillosis: from the bench to the bedside.

S. Seyedmousavi, W. Melchers, P. Verweij, 2014, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Reduction of Surgical-Site Infections in Cardiothoracic Surgery by Elimination of Nasal Carriage of Staphylococcus aureus

H. Verbrugh, A. Maat, J. Mouton, 1996, Infection Control & Hospital Epidemiology.

Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection.

P. Tulkens, R. D. De Jongh, J. Mouton, 2008, The Journal of antimicrobial chemotherapy.

Lung overinflation without positive end-expiratory pressure promotes bacteremia after experimental Klebsiella pneumoniae inoculation

D. Gommers, S. Verbrugge, J. Mouton, 1998, Intensive Care Medicine.

Fundamentals of antimicrobial pharmacokinetics and pharmacodynamics

A. Vinks, H. Derendorf, J. Mouton, 2014 .

Voriconazole efficacy against Candida glabrata and Candida krusei: preclinical data using a validated in vitro pharmacokinetic/pharmacodynamic model.

M. Arendrup, J. Meletiadis, J. Mouton, 2019, The Journal of antimicrobial chemotherapy.

Intra- and Interlaboratory Agreement in Assessing the In Vitro Activity of Micafungin against Common and Rare Candida Species with the EUCAST, CLSI, and Etest Methods

J. Meis, J. Meletiadis, J. Mouton, 2016, Antimicrobial Agents and Chemotherapy.

Continuous infusion of amphotericin B deoxycholate for the treatment of life-threatening Candida infections.

S. Seyedmousavi, D. Andes, P. Verweij, 2013, American journal of respiratory and critical care medicine.

Efficacy and pharmacodynamics of voriconazole combined with anidulafungin in azole-resistant invasive aspergillosis.

S. Seyedmousavi, W. Melchers, P. Verweij, 2013, The Journal of antimicrobial chemotherapy.

Combination therapy as a tool to prevent emergence of bacterial resistance

J. Mouton, 1999, Infection.

Species Aspergillus Testing of Colorimetric Assay for Antifungal Susceptibility

J. Donnelly, P. Verweij, J. Meletiadis, 2001 .

Comparison of NCCLS and 3-(4,5-Dimethyl-2-Thiazyl)-2,5-Diphenyl-2H-Tetrazolium Bromide (MTT) Methods of In Vitro Susceptibility Testing of Filamentous Fungi and Development of a New Simplified Method

J. Donnelly, P. Verweij, J. Meletiadis, 2000, Journal of Clinical Microbiology.

Aspergillus and aspergilloses in wild and domestic animals: a global health concern with parallels to human disease.

S. Seyedmousavi, W. Melchers, G. S. de Hoog, 2015, Medical mycology.

Applying Pharmacodynamics for Susceptibility Breakpoint Selection and Susceptibility Testing

W. Craig, G. Kahlmeter, P. Ambrose, 2007 .

Dose optimization of voriconazole/anidulafungin combination against Aspergillus fumigatus using an in vitro pharmacokinetic/pharmacodynamic model and response surface analysis: clinical implications for azole-resistant aspergillosis.

N. Siafakas, J. Meletiadis, J. Mouton, 2016, The Journal of antimicrobial chemotherapy.

Continuous administration of PBP-2- and PBP-3-specific beta-lactams causes higher cytokine responses in murine Pseudomonas aeruginosa and Escherichia coli sepsis.

J. V. D. van der Meer, A. Dofferhoff, J. Mouton, 2007, The Journal of antimicrobial chemotherapy.

Efficacy of Posaconazole against Three Clinical Aspergillus fumigatus Isolates with Mutations in the cyp51A Gene

W. Melchers, P. Verweij, J. Mouton, 2008, Antimicrobial Agents and Chemotherapy.

Surveillance of postoperative infections in thoracic surgery.

J. Kluytmans, A. Maat, J. Mouton, 1994, The Journal of hospital infection.

Comparison of three commercially available amplification assays, AMP CT, LCx, and COBAS AMPLICOR, for detection of Chlamydia trachomatis in first-void urine

H. Verbrugh, W. Goessens, J. Mouton, 1997, Journal of clinical microbiology.

Molecular epidemiology of Staphylococcus aureus strains colonizing the lungs of related and unrelated cystic fibrosis patients.

A. van Belkum, H. Verbrugh, N. Renders, 1997, Clinical Microbiology and Infection.

Patient-to-patient spread of a single strain of Corynebacterium striatum causing infections in a surgical intensive care unit

H. Bruining, A. van Belkum, H. Verbrugh, 1996, Journal of clinical microbiology.

Zinc-Impregnated Mesh for Abdominal Wall Repair Reduces Infection in a Rat Model of Peritonitis.

J. Jeekel, L. Kroese, G. Kleinrensink, 2019, The Journal of surgical research.

Ciprofloxacin in Polyethylene Glycol-Coated Liposomes: Efficacy in Rat Models of Acute or Chronic Pseudomonas aeruginosa Infection

M. T. ten Kate, I. Bakker-Woudenberg, P. Working, 2002, Antimicrobial Agents and Chemotherapy.

Improved Efficacy of Ciprofloxacin Administered in Polyethylene Glycol-Coated Liposomes for Treatment of Klebsiella pneumoniae Pneumonia in Rats

M. T. ten Kate, I. Bakker-Woudenberg, P. Working, 2001, Antimicrobial Agents and Chemotherapy.

Quantitative assessment of antimicrobial resistance in livestock during the course of a nationwide antimicrobial use reduction in the Netherlands.

D. Heederik, J. Wagenaar, J. Jacobs, 2016, Journal of Antimicrobial Chemotherapy.

Different demographic and sexual correlates for chlamydial infection and gonorrhoea in Rotterdam.

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Effect of Dosing and Dosing Frequency on the Efficacy of Ceftizoxime and the Emergence of Ceftizoxime Resistance during the Early Development of Murine Abscesses Caused by Bacteroides fragilis and Enterobacter cloacae Mixed Infection

I. Gyssens, W. Goessens, J. Mouton, 2007, Antimicrobial Agents and Chemotherapy.

Pulmonary surfactant as vehicle for intratracheally instilled tobramycin in mice infected with Klebsiella pneumoniae

D. Gommers, J. Mouton, B. Lachmann, 1996, British journal of pharmacology.

Effect of growth hormone administration frequency on 24‐hour growth hormone profiles and levels of other growth related parameters in girls with Turner's syndrome *

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Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials.

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Invasive Aspergillosis by Aspergillus flavus: Epidemiology, Diagnosis, Antifungal Resistance, and Management

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M. Arendrup, J. Guinea, P. Verweij, 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Isavuconazole susceptibility of clinical Aspergillus fumigatus isolates and feasibility of isavuconazole dose escalation to treat isolates with elevated MICs

W. Melchers, J. Meis, J. Zoll, 2018, The Journal of antimicrobial chemotherapy.

Multicentre validation of 4-well azole agar plates as a screening method for detection of clinically relevant azole-resistant Aspergillus fumigatus

M. Arendrup, K. Lagrou, P. Verweij, 2017, The Journal of antimicrobial chemotherapy.

In Vivo Efficacy of Liposomal Amphotericin B against Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates in Two Different Immunosuppression Models of Invasive Aspergillosis

S. Seyedmousavi, W. Melchers, P. Verweij, 2017, Antimicrobial Agents and Chemotherapy.

Pharmacodynamics of Voriconazole against Wild-Type and Azole-Resistant Aspergillus flavus Isolates in a Nonneutropenic Murine Model of Disseminated Aspergillosis

S. Seyedmousavi, J. Meis, S. Rudramurthy, 2016, Antimicrobial Agents and Chemotherapy.

Relationship between In Vitro Activities of Amphotericin B and Flucytosine and pH for Clinical Yeast and Mold Isolates

J. Meis, P. Verweij, J. Mouton, 2005, Antimicrobial Agents and Chemotherapy.

Multicentre determination of rezafungin (CD101) susceptibility of Candida species by the EUCAST method.

M. Arendrup, J. Guinea, M. Cuenca‐Estrella, 2018, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

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M. Falagas, W. Ko, U. Theuretzbacher, 2013, Journal of global antimicrobial resistance.

Is continuous infusion of beta-lactam antibiotics worthwhile?--efficacy and pharmacokinetic considerations.

A. Vinks, J. Mouton, 1996, The Journal of antimicrobial chemotherapy.

Reviving old antibiotics.

J. Turnidge, R. Nation, G. Kahlmeter, 2015, The Journal of antimicrobial chemotherapy.

A multi-center blinded study on the efficiency of phenotypic screening methods to detect glycopeptide intermediately susceptible Staphylococcus aureus (GISA) and heterogeneous GISA (h-GISA)

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Typing of Pseudomonas aeruginosa strains from patients with cystic fibrosis: phenotyping versus genotyping.

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Antimicrobial prescription patterns of veterinarians: introduction of a benchmarking approach.

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Efficacy and Pharmacodynamics of Flucytosine Monotherapy in a Nonneutropenic Murine Model of Invasive Aspergillosis

J. Meis, P. Verweij, J. Mouton, 2005, Antimicrobial Agents and Chemotherapy.

A fast and sensitive LC-MS/MS method for the quantification of fosfomycin in human urine and plasma using one sample preparation method and HILIC chromatography.

T. van Gelder, J. Mouton, B. Koch, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Synergism between tobramycin and ceftazidime against a resistant Pseudomonas aeruginosa strain, tested in an in vitro pharmacokinetic model

Hollander, H. Verbrugh, J. Mouton, 1997, Antimicrobial agents and chemotherapy.

Meropenem Clinical Pharmacokinetics

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Treatment outcomes of colistin and carbapenem-resistant Acinetobacter baumannii infections: an exploratory subgroup analysis of a randomized clinical trial.

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S. Seyedmousavi, W. Melchers, P. Verweij, 2012, Antimicrobial Agents and Chemotherapy.

Vancomycin population pharmacokinetics in neonates

R. Schoemaker, J. Mouton, J. Anker, 2000, Clinical pharmacology and therapeutics.

Tobramycin population pharmacokinetics in neonates *

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Setting Clinical MIC Breakpoints from a PK/PD Point of View: It Is the Dose That Matters

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Vancomycin: pharmacokinetics and administration regimens in neonates.

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Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development

J. Roberts, J. Lipman, J. Mouton, 2015, Seminars in Respiratory and Critical Care Medicine.

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions.

Michael N Neely, Jason A Roberts, Jerome J. Schentag, 2014, The Lancet. Infectious diseases.

New dosing strategies for antibacterial agents in the neonate.

J. N. van den Anker, M. de Hoog, J. Mouton, 2005, Seminars in fetal & neonatal medicine.

Why monitor peak vancomycin concentrations?

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Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update.

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Pharmacokinetics of sequential intravenous and enteral fluconazole in critically ill surgical patients with invasive mycoses and compromised gastro-intestinal function

H. Bruining, I. Gyssens, H. Verbrugh, 2001, Intensive Care Medicine.

Novel model-based dosing guidelines for gentamicin and tobramycin in preterm and term neonates.

Johan W Mouton, Catherijne A J Knibbe, Karel Allegaert, 2015, The Journal of antimicrobial chemotherapy.

Extended‐interval dosing of tobramycin in neonates: Implications for therapeutic drug monitoring

R. Schoemaker, J. Mouton, J. Anker, 2002, Clinical pharmacology and therapeutics.

Composite Survival Index to Compare Virulence Changes in Azole-Resistant Aspergillus fumigatus Clinical Isolates

T. Heskes, W. Melchers, M. Arendrup, 2013, PloS one.

The Role of New Posaconazole Formulations in the Treatment of Candida albicans Infections: Data from an In Vitro Pharmacokinetic-Pharmacodynamic Model

M. Arendrup, D. Andes, J. Meletiadis, 2021, Antimicrobial Agents and Chemotherapy.

Toward Harmonization of Voriconazole CLSI and EUCAST Breakpoints for Candida albicans Using a Validated In Vitro Pharmacokinetic/Pharmacodynamic Model

M. Arendrup, D. Andes, J. Meletiadis, 2020, Antimicrobial Agents and Chemotherapy.

Susceptibility breakpoints and target values for therapeutic drug monitoring of voriconazole and Aspergillus fumigatus in an in vitro pharmacokinetic/pharmacodynamic model.

P. Verweij, J. Meletiadis, J. Mouton, 2014, The Journal of antimicrobial chemotherapy.

Inhibitory and Fungicidal Effects of Antifungal Drugs against Aspergillus Species in the Presence of Serum

P. Verweij, J. Meletiadis, J. Mouton, 2013, Antimicrobial Agents and Chemotherapy.

Impact of cyp51A Mutations on the Pharmacokinetic and Pharmacodynamic Properties of Voriconazole in a Murine Model of Disseminated Aspergillosis

W. Melchers, P. Verweij, J. Mouton, 2010, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and Pharmacodynamics of Azoles

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Towards Rational Dosing Algorithms for Vancomycin in Neonates and Infants Based on Population Pharmacokinetic Modeling

J. N. van den Anker, C. Knibbe, Pyry A. J. Välitalo, 2015, Antimicrobial Agents and Chemotherapy.

Method for Measuring Postantifungal Effect in Aspergillus Species

J. Meis, P. Verweij, J. Mouton, 2002, Antimicrobial Agents and Chemotherapy.

Amphotericin B and terbinafine but not the azoles prolong survival in Galleria mellonella larvae infected with Madurella mycetomatis

Wendy Kloezen, A. Fahal, J. Mouton, 2018, Medical mycology.

Comparative Pharmacokinetics of the Carbapenems

A. Vinks, D. Touw, J. Mouton, 2000, Clinical pharmacokinetics.

In-vitro activity of quinupristin/dalfopristin compared with other widely used antibiotics against strains isolated from patients with endocarditis.

H. Endtz, H. Verbrugh, N. van den Braak, 1997, The Journal of antimicrobial chemotherapy.

Serum concentrations of amoxicillin in neonates during continuous intravenous infusion

J. Mouton, C. Kramers, P. Gerrits, 2016, European Journal of Clinical Microbiology & Infectious Diseases.

Analysis of Growth Characteristics of Filamentous Fungi in Different Nutrient Media

J. Meis, P. Verweij, J. Meletiadis, 2001, Journal of Clinical Microbiology.

Efficacy of Antifungal Therapy in a Nonneutropenic Murine Model of Zygomycosis

J. Meis, P. Verweij, E. Dannaoui, 2002, Antimicrobial Agents and Chemotherapy.

The Strength of Synergistic Interaction between Posaconazole and Caspofungin Depends on the Underlying Azole Resistance Mechanism of Aspergillus fumigatus

P. Verweij, J. Meletiadis, J. Mouton, 2015, Antimicrobial Agents and Chemotherapy.

In Vitro Interaction of Voriconazole and Anidulafungin against Triazole-Resistant Aspergillus fumigatus

S. Seyedmousavi, W. Melchers, P. Verweij, 2012, Antimicrobial Agents and Chemotherapy.

Colorimetric Assay for Antifungal Susceptibility Testing ofAspergillus Species

J. Donnelly, P. Verweij, J. Meletiadis, 2001, Journal of Clinical Microbiology.

Oral amoxicillin and amoxicillin-clavulanate: properties, indications, and usage.

J. Bielicki, A. Huttner, J. Mouton, 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Comparison of Fractional Inhibitory Concentration Index with Response Surface Modeling for Characterization of In Vitro Interaction of Antifungals against Itraconazole-Susceptible and -Resistant Aspergillus fumigatus Isolates

J. Meis, P. Verweij, J. Mouton, 2002, Antimicrobial Agents and Chemotherapy.

The Predictive Value of Laboratory Tests for Efficacy of Antibiotic Combination Therapy

J. Mouton, J. D. Hollander, 2007 .

In Vitro Interaction of Terbinafine with Itraconazole against Clinical Isolates of Scedosporium prolificans

P. Verweij, J. Rodríguez-Tudela, J. Meletiadis, 2000, Antimicrobial Agents and Chemotherapy.

Shortening the incubation time for antimicrobial susceptibility testing by disk diffusion for Enterobacteriaceae: how short can it be and are the results accurate?

A. Buiting, J. Mouton, A. Muller, 2017, International journal of antimicrobial agents.

Azole-Resistant Aspergillus fumigatus, Iran

S. Seyedmousavi, W. Melchers, J. Zoll, 2013, Emerging infectious diseases.

Methodological issues related to antifungal drug interaction modelling for filamentous fungi

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Pharmacokinetics of Itraconazole and Hydroxyitraconazole in Healthy Subjects after Single and Multiple Doses of a Novel Formulation

J. Donnelly, J. Mouton, A. V. van Vliet, 2006, Antimicrobial Agents and Chemotherapy.

EUCAST technical note on isavuconazole breakpoints for Aspergillus, itraconazole breakpoints for Candida and updates for the antifungal susceptibility testing method documents.

M. Arendrup, J. Guinea, M. Cuenca‐Estrella, 2016, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Evaluation of the post-antifungal effect (PAFE) of amphotericin B and nystatin against 30 zygomycetes using two different media.

J. Meis, P. Verweij, J. Mouton, 2003, The Journal of antimicrobial chemotherapy.

In vitro activity of isavuconazole against 208 Aspergillus flavus isolates in comparison with 7 other antifungal agents: assessment according to the methodology of the European Committee on Antimicrobial Susceptibility Testing.

J. Meis, S. Rudramurthy, A. Chakrabarti, 2011, Diagnostic microbiology and infectious disease.

P1978 In vitro activity of isavuconazole (BAL4815) compared with seven other antifungal agents against 309 prospectively collected clinical Candida isolates from the Netherlands

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Susceptibility Breakpoints for Amphotericin B and Aspergillus Species in an In Vitro Pharmacokinetic-Pharmacodynamic Model Simulating Free-Drug Concentrations in Human Serum

P. Verweij, J. Meletiadis, J. Mouton, 2014, Antimicrobial Agents and Chemotherapy.

In Vitro Interaction of Flucytosine Combined with Amphotericin B or Fluconazole against Thirty-Five Yeast Isolates Determined by both the Fractional Inhibitory Concentration Index and the Response Surface Approach

M. Bergervoet, P. E. Verweij, J. Meis, 2002, Antimicrobial Agents and Chemotherapy.

Cefadroxil, cephaloridine, cephacetrile, cephapirin, cephradine, and other rarely used first-generation cephalosporins

William W. Hope, Sara E. Cosgrove, S. Cosgrove, 2017 .

Comparison of the Etest and the Sensititre Colorimetric Methods with the NCCLS Proposed Standard for Antifungal Susceptibility Testing of Aspergillus Species

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Exogenous pulmonary surfactant as a drug delivering agent: influence of antibiotics on surfactant activity

D. Gommers, J. Kluytmans, J. Mouton, 1996, British journal of pharmacology.

Widespread implementation of EUCAST breakpoints for antibacterial susceptibility testing in Europe.

A. MacGowan, M. Struelens, M. Steinbakk, 2015, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

Failure of Posaconazole Therapy in a Renal Transplant Patient with Invasive Aspergillosis Due to Aspergillus fumigatus with Attenuated Susceptibility to Posaconazole

W. Melchers, P. Verweij, J. Mouton, 2011, Antimicrobial Agents and Chemotherapy.

In Vitro Interactions between Amphotericin B, Itraconazole, and Flucytosine against 21 Clinical Aspergillus Isolates Determined by Two Drug Interaction Models

J. Meis, P. Verweij, J. Mouton, 2004, Antimicrobial Agents and Chemotherapy.

In vitro susceptibility of 188 clinical and environmental isolates of Aspergillus flavus for the new triazole isavuconazole and seven other antifungal drugs

J. Meis, A. Chakrabarti, J. Mouton, 2011, Mycoses.

Resistance of Asian Cryptococcus neoformans Serotype A Is Confined to Few Microsatellite Genotypes

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Fosfomycin: Pharmacological, Clinical and Future Perspectives

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Impact of bacterial species and baseline resistance on fosfomycin efficacy in urinary tract infections.

A. Peleg, J. Meletiadis, J. Mouton, 2019, The Journal of antimicrobial chemotherapy.

Enzymatic method for inactivation of aminoglycosides during measurement of postantibiotic effect

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EUCAST expert rules in antimicrobial susceptibility testing.

A P MacGowan, G Kahlmeter, P. Nordmann, 2013, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

A Novel Y319H Substitution in CYP51C Associated with Azole Resistance in Aspergillus flavus

J. Meis, S. Rudramurthy, A. Chakrabarti, 2015, Antimicrobial Agents and Chemotherapy.

Combination chemotherapy for the treatment of invasive infections by Scedosporium prolificans.

J. Meis, P. Verweij, J. Meletiadis, 2000, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Pharmacokinetic and pharmacodynamic studies of beta-lactam antibiotics in volunteers and patients with cystic fibrosis

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Duration and Clinical Relevance of Postantibiotic Effect in Relation to the Dosing Interval

H. Verbrugh, K. Fuursted, J. Mouton, 1998, Antimicrobial Agents and Chemotherapy.

In Vitro and In Vivo Exposure-Effect Relationship of Liposomal Amphotericin B against Aspergillus fumigatus

S. Pournaras, J. Meletiadis, J. Mouton, 2019, Antimicrobial Agents and Chemotherapy.

Dose-response relationships of three amphotericin B formulations in a non-neutropenic murine model of invasive aspergillosis.

J. Meis, P. Verweij, J. Mouton, 2009, Medical mycology.

Potent Synergistic In Vitro Interaction between Nonantimicrobial Membrane-Active Compounds and Itraconazole against Clinical Isolates of Aspergillus fumigatus Resistant to Itraconazole

P. Verweij, J. Mouton, R. Vitale, 2004, Antimicrobial Agents and Chemotherapy.

Development and multicentre validation of an agar-based screening method for echinocandin susceptibility testing of Aspergillus species.

M. Arendrup, D. Perlin, J. Meletiadis, 2019, The Journal of antimicrobial chemotherapy.

Shortening the incubation time for the combination disk diffusion extended-spectrum β-lactamase (ESBL) confirmation test: how far can we go?

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O435 Prevalence of ESBL in the Netherlands: the ONE study

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EUCAST technical note on tigecycline.

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Kucers’ the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs, seventh edition

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The synthetic synergistic cinnamon oil CIN-102 is active against Madurella mycetomatis, the most common causative agent of mycetoma

A. Fahal, J. Mouton, W. V. D. van de Sande, 2021, PLoS neglected tropical diseases.

In vitro susceptibilities of Zygomycota to polyenes.

J. Meis, P. Verweij, E. Dannaoui, 2002, The Journal of antimicrobial chemotherapy.

Conserving antibiotics for the future: new ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective.

Stephan Harbarth, Johan W Mouton, John Turnidge, 2011, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

A retrospective analysis using Monte Carlo simulation to evaluate recommended ceftazidime dosing regimens in healthy volunteers, patients with cystic fibrosis, and patients in the intensive care unit.

A. Vinks, J. Mouton, N. Punt, 2005, Clinical therapeutics.

EUCAST Testing of Isavuconazole Susceptibility in Aspergillus: Comparison of Results for Inoculum Standardization Using Conidium Counting versus Optical Density

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Amphotericin B- and Voriconazole-Echinocandin Combinations against Aspergillus spp.: Effect of Serum on Inhibitory and Fungicidal Interactions

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Protein Binding: Do We Ever Learn?

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MINIREVIEW Protein Binding: Do We Ever Learn?

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Use of a Novel Panel of Nine Short Tandem Repeats for Exact and High-Resolution Fingerprinting of Aspergillus fumigatus Isolates

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In Vitro Activities of Pentamidine, Pyrimethamine, Trimethoprim, and Sulfonamides against Aspergillus Species

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Pharmacodynamics and Dose-Response Relationships of Liposomal Amphotericin B against Different Azole-Resistant Aspergillus fumigatus Isolates in a Murine Model of Disseminated Aspergillosis

S. Seyedmousavi, W. Melchers, P. Verweij, 2013, Antimicrobial Agents and Chemotherapy.

Antifungal Susceptibility Patterns of Opportunistic Fungi in the Genera Verruconis and Ochroconis

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A multicentre study to optimize echinocandin susceptibility testing of Aspergillus species with the EUCAST methodology and a broth microdilution colorimetric method.

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P1977 In vitro activity of isavuconazole (BAL4815/8557) compared with six other antifungal agents against 180 Cryptococcus neoformans meningitis isolates from the Netherlands

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Epidemiological Cutoff Values for Azoles and Aspergillus fumigatus Based on a Novel Mathematical Approach Incorporating cyp51A Sequence Analysis

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In Vitro Activities at pH 5.0 and pH 7.0 and In Vivo Efficacy of Flucytosine against Aspergillus fumigatus

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Exposure-Response Relationships for Isavuconazole in Patients with Invasive Aspergillosis and Other Filamentous Fungi

P. Bonate, S. Mujais, D. Andes, 2017, Antimicrobial Agents and Chemotherapy.

European harmonization of MIC breakpoints for antimicrobial susceptibility testing of bacteria.

Johan W Mouton, Martin Steinbakk, A. MacGowan, 2003, The Journal of antimicrobial chemotherapy.

Use of Pharmacodynamic Indices To Predict Efficacy of Combination Therapy In Vivo

W. Craig, D. Andes, J. Mouton, 1999, Antimicrobial Agents and Chemotherapy.

Use of Pharmacodynamic Parameters To Predict Efficacy of Combination Therapy by Using Fractional Inhibitory Concentration Kinetics

H. Verbrugh, J. Mouton, J. D. den Hollander, 1998, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics of ceftazidime in serum and suction blister fluid during continuous and intermittent infusions in healthy volunteers

E. Prens, P. Mulder, J. Mouton, 1990, Antimicrobial Agents and Chemotherapy.

In vitro pharmacokinetic/pharmacodynamic model data suggest a potential role of new formulations of posaconazole against C. krusei but not C. glabrata infections.

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European Society of clinical microbiology and infectious diseases (ESCMID) guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli (endorsed by ESICM -European Society of intensive care Medicine).

K. Seme, R. Bonomo, M. Bassetti, 2021, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Recommendations of the NVMM Guideline Laboratory detection of highly resistant microorganisms

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Bacteroides fragilis in biopsies of patients with major abscesses and diabetic foot infections: direct molecular versus culture-based detection.

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Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial.

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The DUEL study: a multi-center in vitro evaluation of linezolid compared with other antibiotics in the Netherlands.

J. Mouton, A. Jansz, 2001, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Pharmacokinetic/pharmacodynamic analysis of oral fosfomycin against Enterobacterales, Pseudomonas aeruginosa and Enterococcus spp. in an in vitro bladder infection model: impact on clinical breakpoints.

A. Peleg, J. Meletiadis, J. Mouton, 2021, The Journal of antimicrobial chemotherapy.

Performance of an ESBL-PCR assay for rapid and direct detection of ESBL carriage from 1 rectal swabs and enrichment broth 2 3

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The epidemiology of vaginal colonisation with group B streptococci in a sexually transmitted disease clinic.

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Rapid and reliable identification of Streptococcus anginosus group isolates to the species level by real-time PCR and melting curve analysis.

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Lung clearance of intratracheally instilled 99mTc‐tobramycin using pulmonary surfactant as vehicle

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Colistin plus meropenem for carbapenem-resistant gram-negative infections: in vitro synergism is not associated with better clinical outcomes.

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Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus.

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Modelling concentrations of antimicrobial drugs: comparative pharmacokinetics of cephalosporin antimicrobials and accuracy of allometric scaling in food-producing and companion animals

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Combining VITEK® 2 with colistin agar dilution screening assist timely reporting of colistin susceptibility.

Y. Carmeli, D. Yahav, A. Skiada, 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Combination therapy for carbapenem-resistant Gram-negative bacteria.

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Fosfomycin Etest for Enterobacteriaceae: Interobserver and interlaboratory agreement.

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Experience with a once-daily dosing program of aminoglycosides in critically ill patients

H. Bruining, I. Gyssens, H. Verbrugh, 2002, Intensive Care Medicine.

Pharmacodynamics of tobramycin in patients with cystic fibrosis.

H. Tiddens, J. Mouton, A. Horrevorts, 2005, Diagnostic microbiology and infectious disease.

Continuous infusion of beta-lactams

A. Vinks, J. Mouton, 2007, Current opinion in critical care.

Pharmacokinetics of meropenem in serum and suction blister fluid during continuous and intermittent infusion.

J. Mouton, M. Michel, M. Michel, 1991, The Journal of antimicrobial chemotherapy.

Review of the pharmacokinetic properties of nitrofurantoin and nitroxoline

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OP-JANM180256 2916..2926

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Development and validation of a fast and sensitive UHPLC-DAD assay for the quantification of nitrofurantoin in plasma and urine.

J. Mouton, R. Brüggemann, R. Wijma, 2019, Journal of pharmaceutical and biomedical analysis.

Vancomycin population pharmacokinetics in neonates.

J. N. van den Anker, M. de Hoog, R. Schoemaker, 2000, Clinical pharmacology and therapeutics.

Transmission of hepatitis B virus among heart transplant recipients during endomyocardial biopsy procedures.

R. D. de Man, A. Balk, A. Osterhaus, 1998, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Methodological features of clinical pharmacokinetic-pharmacodynamic studies of antibacterials and antifungals: a systematic review.

J. Higgins, G. Drusano, A. MacGowan, 2020, The Journal of antimicrobial chemotherapy.

Evaluation of Clearview and Magic Lite tests, polymerase chain reaction, and cell culture for detection of Chlamydia trachomatis in urogenital specimens

W. Quint, H. Niesters, J. Kluytmans, 1993, Journal of clinical microbiology.

In Vitro Activity of Ceftazidime-Avibactam Combination in In Vitro Checkerboard Assays

J. Mouton, W. Nichols, M. Melchers, 2014, Antimicrobial Agents and Chemotherapy.

Two versus five days of antibiotics after appendectomy for complex acute appendicitis (APPIC): study protocol for a randomized controlled trial

M. Boermeester, M. Koopmanschap, E. Consten, 2018, Trials.

Colonization and infection by Serratia species in a paediatric surgical intensive care unit.

D. Tibboel, J. Mouton, M. Albers, 2001, The Journal of hospital infection.

Exchange of Pseudomonas aeruginosa strains among cystic fibrosis siblings.

A. van Belkum, H. Verbrugh, N. Renders, 1997, Research in microbiology.

Emergence of antibiotic resistance amongst Pseudomonas aeruginosa isolates from patients with cystic fibrosis.

J. Mouton, A. Horrevorts, J. D. den Hollander, 1993, The Journal of antimicrobial chemotherapy.

Antibacterial therapy in cystic fibrosis.

J. Mouton, K. Kerrebijn, 1990, The Medical clinics of North America.

Killing of Pseudomonas aeruginosa during continuous and intermittent infusion of ceftazidime in an in vitro pharmacokinetic model

J. Mouton, J. D. den Hollander, Den, 1994, Antimicrobial Agents and Chemotherapy.

Clinical Impact of Preincubation of Blood Cultures at 37°C

P. Sturm, J. Mouton, F. Vos, 2010, Journal of Clinical Microbiology.

The pharmacokinetics of nitrofurantoin in healthy female volunteers: a randomized crossover study.

S. Harbarth, A. Huttner, J. Mouton, 2019, The Journal of antimicrobial chemotherapy.

Evaluation of the post-antibiotic effect in vivo for the combination of a β-lactam antibiotic and a β-lactamase inhibitor: ceftazidime-avibactam in neutropenic mouse thigh and lung infections

J. Mouton, W. Nichols, M. Melchers, 2021, Journal of chemotherapy.

An alternative strategy for combination therapy: Interactions between polymyxin B and non-antibiotics.

S. van den Berg, Wendy Kloezen, J. Meletiadis, 2019, International journal of antimicrobial agents.

Pharmacodynamics of Levofloxacin and Ciprofloxacin in a Murine Pneumonia Model: Peak Concentration/MIC versus Area under the Curve/MIC Ratios

R. Mattina, F. Fraschini, F. Scaglione, 2003, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics of ceftazidime in serum and peritoneal exudate during continuous versus intermittent administration to patients with severe intra-abdominal infections.

H. Bruining, I. Gyssens, H. Verbrugh, 2002, The Journal of antimicrobial chemotherapy.

Pharmacokinetics of Aztreonam in Healthy Subjects and Patients with Cystic Fibrosis and Evaluation of Dose-Exposure Relationships Using Monte Carlo Simulation

A. Vinks, R. Mathôt, J. Mouton, 2007, Antimicrobial Agents and Chemotherapy.

Non-linear absorption pharmacokinetics of amoxicillin: consequences for dosing regimens and clinical breakpoints.

T. van Gelder, B. D. de Winter, J. Mouton, 2016, The Journal of antimicrobial chemotherapy.

WHY MONITOR PEAK VANCOMYCIN CONCENTRATIONS ? AUTHOR'S REPLY

M. Wysocki, N. Saunders, S. Duffull, 1995 .

Comparative in vitro activities of trovafloxacin (CP-99,219) against 445 gram-positive isolates from patients with endocarditis and those with other bloodstream infections

H. Endtz, H. Verbrugh, N. van den Braak, 1997, Antimicrobial agents and chemotherapy.

Prevention of respiratory failure after hydrochloric acid aspiration by intratracheal surfactant instillation in rats.

D. Gommers, M. D. de Maat, J. Mouton, 1993, Anesthesia and analgesia.

Consumption of Antimicrobials in Pigs, Veal Calves, and Broilers in The Netherlands: Quantitative Results of Nationwide Collection of Data in 2011

D. Heederik, D. Mevius, M. Bos, 2013, PloS one.

Pharmacodynamics of Cefepime Combined with Tazobactam against Clinically Relevant Enterobacteriaceae in a Neutropenic Mouse Thigh Model

J. den Hartigh, J. Mouton, M. Melchers, 2017, Antimicrobial Agents and Chemotherapy.

Use of the t > MIC to choose between different dosing regimens of beta-lactam antibiotics.

J. Mouton, N. Punt, 2001, The Journal of antimicrobial chemotherapy.

Plasma and Epithelial Lining Fluid Pharmacokinetics of Ceftolozane and Tazobactam Alone and in Combination in Mice

S. Seyedmousavi, J. Mouton, M. Melchers, 2015, Antimicrobial Agents and Chemotherapy.

Concentration-Effect Relationship of Ceftazidime Explains Why the Time above the MIC Is 40 Percent for a Static Effect In Vivo

A. Vinks, J. Mouton, N. Punt, 2007, Antimicrobial Agents and Chemotherapy.

Pharmacokinetic Optimisation of Antibacterial Treatment in Patients with Cystic Fibrosis

A. Vinks, D. Touw, J. Mouton, 1998, Clinical pharmacokinetics.

Fosfomycin efficacy and emergence of resistance among Enterobacteriaceae in an in vitro dynamic bladder infection model

A. Peleg, J. Roberts, J. Meletiadis, 2018, The Journal of antimicrobial chemotherapy.

Reduced subcutaneous tissue distribution of cefazolin in morbidly obese versus non-obese patients determined using clinical microdialysis.

B. van Ramshorst, E. Hazebroek, V. Deneer, 2014, The Journal of antimicrobial chemotherapy.

Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial

L. Leibovici, D. Yahav, X. Roux, 2018, JAMA.

The fate of inhaled antibiotics after deposition in cystic fibrosis: How to get drug to the bug?

H. Tiddens, H. Janssens, J. Mouton, 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Decreased ciprofloxacin susceptibility in Salmonella Typhi and Paratyphi infections in ill-returned travellers: the impact on clinical outcome and future treatment options

W. Goessens, A. Verbon, D. Mevius, 2013, European Journal of Clinical Microbiology & Infectious Diseases.

Variation of MIC measurements: the contribution of strain and laboratory variability to measurement precision-authors' response.

J. Turnidge, A. Voss, J. Meletiadis, 2019, The Journal of antimicrobial chemotherapy.

Non-adherence to antimicrobial treatment guidelines results in more broad-spectrum but not more appropriate therapy

B. Kullberg, P. Pickkers, J. Mouton, 2011, European Journal of Clinical Microbiology & Infectious Diseases.

Pharmacokinetics and Pharmacodynamics of Murepavadin in Neutropenic Mouse Models

G. Dale, D. Obrecht, A. Wach, 2019, Antimicrobial Agents and Chemotherapy.

Binding of temocillin to plasma proteins in vitro and in vivo: the importance of plasma protein levels in different populations and of co-medications.

M. Zeitlinger, P. Laterre, P. Tulkens, 2022, The Journal of antimicrobial chemotherapy.

Prevalence and molecular mechanism of macrolide resistance in beta-haemolytic streptococci in The Netherlands.

W. Melchers, J. Mouton, C. Klaassen, 2010, International journal of antimicrobial agents.

Tubal factor pathology caused by Chlamydia trachomatis: The role of serology

J. Mouton, R. Verkooyen, M. Peeters, 2002, International Journal of STD and AIDS.

Decreased ciprofloxacin susceptibility in Salmonella Typhi and Paratyphi infections in ill-returned travellers: the impact on clinical outcome and future treatment options

P. V. van Genderen, W. Goessens, A. Verbon, 2013, European Journal of Clinical Microbiology & Infectious Diseases.

Which cephalosporin for gonorrhoea?

D. Livermore, K. Fenton, J. Mouton, 2004, Sexually Transmitted Infections.

Chlamydia antibody testing and diagnosing tubal pathology in subfertile women: an individual patient data meta-analysis.

J A Land, E. Ng, J. W. van der Steeg, 2011, Human reproduction update.

Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink?

D. Livermore, T. Nichols, J. Mouton, 2010, The Journal of antimicrobial chemotherapy.

Pharmacokinetics and Target Attainment of Ceftobiprole in Asian and Non‐Asian Subjects

A. Schmitt-Hoffmann, J. Mouton, A. Muller, 2018, Clinical pharmacology in drug development.

Diagnostic and medical needs for therapeutic drug monitoring of antibiotics

A. van Belkum, D. Nicolau, J. Roberts, 2019, European Journal of Clinical Microbiology & Infectious Diseases.

A role for TLR1, TLR2 and NOD2 in cytokine induction by Bacteroides fragilis.

M. Oosting, L. Joosten, M. Netea, 2012, Cytokine.

Exposure to Ceftobiprole Is Associated with Microbiological Eradication and Clinical Cure in Patients with Nosocomial Pneumonia

J. Mouton, A. Muller, Natalie Punt, 2014, Antimicrobial Agents and Chemotherapy.

Monte Carlo Simulations Based on Phase 1 Studies Predict Target Attainment of Ceftobiprole in Nosocomial Pneumonia Patients: a Validation Study

A. Schmitt-Hoffmann, J. Mouton, A. Muller, 2013, Antimicrobial Agents and Chemotherapy.

Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA

J. Lebbink, W. V. van Cappellen, P. J. van der Spek, 2020, Science Advances.

Sensitivity and specificity of three new commercially available Chlamydia trachomatis tests

J. Mouton, W. I. van der Meijden, R. Verkooyen, 2002, International journal of STD & AIDS.

Delta APACHE II for predicting course and outcome of nosocomial Staphylococcus aureus bacteremia and its relation to host defense.

H. Verbrugh, J. Kluytmans, J. Kluytmans, 1996, The Journal of infectious diseases.

Pathophysiology of in-vitro induced filaments, spheroplasts and rod-shaped bacteria in neutropenic mice.

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Role of ceftazidime dose regimen on the selection of resistant Enterobacter cloacae in the intestinal flora of rats treated for an experimental pulmonary infection.

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Consistent global approach on reporting of colistin doses to promote safe and effective use.

O. Cars, V. Tam, J. Turnidge, 2013, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

In Vivo Efficacy of Trovafloxacin against Bacteroides fragilis in Mixed Infection with either Escherichia coli or a Vancomycin-Resistant Strain of Enterococcus faecium in an Established-Abscess Murine Model

W. Oyen, I. Gyssens, H. Verbrugh, 2001, Antimicrobial Agents and Chemotherapy.

Cefpirome Treatment Results in Limited Selection of Stable Derepressed Enterobacter cloacae Mutants in the Intestinal Flora of Rats Treated for an Experimental Klebsiella pneumoniae Pulmonary Infection.

M. T. ten Kate, I. Bakker-Woudenberg, W. Goessens, 2020, Microbial drug resistance.

CHAPTER 4 – Pharmacodynamics of anti-infective agents: target delineation and susceptibility breakpoint selection

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Use of Monte Carlo Simulations To Select Therapeutic Doses and Provisional Breakpoints of BAL9141

A. Schmitt-Hoffmann, J. Mouton, S. Shapiro, 2004, Antimicrobial Agents and Chemotherapy.

Fosfomycin as a potential therapy for the treatment of systemic infections: a population pharmacokinetic model to simulate multiple dosing regimens

J. Stevens, D. Touw, C. van Nieuwkoop, 2018, Pharmacology research & perspectives.

Performance of a nonisotopic DNA probe for detection of Chlamydia trachomatis in urogenital specimens

W. Quint, H. Niesters, J. Kluytmans, 1991, Journal of clinical microbiology.

The clinical impact of preincubation of blood cultures at 37 ° C 1

P. Sturm, J. Mouton, F. Vos, 2010 .

Can group B streptococci cause symptomatic vaginitis?

J. Mouton, W. I. van der Meijden, E. Honig, 1999, Infectious diseases in obstetrics and gynecology.

Detection of Chlamydia trachomatis in male and female urine specimens by using the amplified Chlamydia trachomatis test

H. Verbrugh, J. Kluytmans, W. Goessens, 1997, Journal of clinical microbiology.

Non-adherence to antimicrobial treatment guidelines results in more broad-spectrum but not more appropriate therapy

M. Hulscher, B. Kullberg, P. Pickkers, 2011, European Journal of Clinical Microbiology & Infectious Diseases.

Evaluation of pooled human urine and synthetic alternatives in a dynamic bladder infection in vitro model simulating oral fosfomycin therapy.

A. Peleg, J. Meletiadis, J. Mouton, 2020, Journal of microbiological methods.

Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria.

P. Jansen, J. Schalkwijk, F. Rutjes, 2013, Antimicrobial agents and chemotherapy.

MINIREVIEW Molecular Detection of the Macrolide Efﬂux Gene: To Discriminate or Not To Discriminate between mef (A) and mef (E)

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Extensive Genetic Diversity within the Dutch Clinical Cryptococcus neoformans Population

J. Meis, T. Boekhout, F. Hagen, 2012, Journal of Clinical Microbiology.

Perioperative pharmacokinetics of cefotaxime in serum and bile during continuous and intermittent infusion in liver transplant patients.

H. Bruining, I. Gyssens, H. Verbrugh, 2004, The Journal of antimicrobial chemotherapy.

Pharmacokinetic-pharmacodynamic modeling of activity of ceftazidime during continuous and intermittent infusion

A. Vinks, J. Mouton, A A Vinks, 1997, Antimicrobial agents and chemotherapy.

Genetic Variation in TLR10, an Inhibitory Toll-Like Receptor, Influences Susceptibility to Complicated Skin and Skin Structure Infections.

M. Oosting, L. Joosten, M. Netea, 2015, The Journal of infectious diseases.

In Vitro Antifungal Susceptibility Testing of Candida Isolates with the EUCAST Methodology, a New Method for ECOFF Determination

J. Meis, J. Meletiadis, J. Mouton, 2017, Antimicrobial Agents and Chemotherapy.

Susceptibility of ESBL Escherichia coli and Klebsiella pneumoniae to fosfomycin in the Netherlands and comparison of several testing methods including Etest, MIC test strip, Vitek2, Phoenix and disc diffusion

B. Diederen, M. Schijffelen, J. Mouton, 2018, The Journal of antimicrobial chemotherapy.

Antibiotic treatment in cystic fibrosis: Part 1: Introduction: Clinical pharmacokinetics and toxicology

A. Vinks, D. Touw, J. Mouton, 2000 .

Excluded versus included patients in a randomized controlled trial of infections caused by carbapenem-resistant Gram-negative bacteria: relevance to external validity

L. Leibovici, Y. Carmeli, O. Zusman, 2021, BMC Infectious Diseases.

Population pharmacokinetics of colistin and the relation to survival in critically ill patients infected with colistin susceptible and carbapenem-resistant bacteria.

L. Leibovici, Y. Carmeli, M. Karlsson, 2020, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Evaluation of Etest To Determine Tigecycline MICs for Enterobacter Species

B. Diederen, A. Fluit, J. Mouton, 2010, Antimicrobial Agents and Chemotherapy.

, R . Tigecycline and Acinetobacter baumannii to Susceptibility of Enterobacteriaceae Vitro In Effect of Manganese in Test Media on

J. Kluytmans, C. Verhulst, J. Mouton, 2012 .

Breakpoints: current practice and future perspectives.

Johan W Mouton, J. Mouton, 2002, International journal of antimicrobial agents.

A structural comparison of lipopolysaccharide biosynthesis loci of Legionella pneumophila serogroup 1 strains

K. Heuner, C. Lück, J. Mouton, 2013, BMC Microbiology.

Global survey of polymyxin use: A call for international guidelines☆

O. Cars, H. Wertheim, R. Laxminarayan, 2013, Journal of global antimicrobial resistance.

Efficacy of single and multiple oral doses of fosfomycin against Pseudomonas aeruginosa urinary tract infections in a dynamic in vitro bladder infection model.

A. Peleg, J. Meletiadis, J. Mouton, 2020, The Journal of antimicrobial chemotherapy.

Update on antibacterial and antifungal drugs - can we master the resistance crisis?

U. Theuretzbacher, J. Mouton, 2011, Current opinion in pharmacology.

Prevention of invasive aspergillosis in AIDS by sulfamethoxazole.

J. Meis, P. Verweij, J. Mouton, 2001, AIDS.

Population pharmacokinetics of vancomycin in obesity: Finding the optimal dose for (morbidly) obese individuals

M. Wiezer, C. Knibbe, J. Mouton, 2020, British journal of clinical pharmacology.

Susceptibility to various antimicrobial agents and tolerance to methicillin ofStaphylococcus aureus isolates from cystic fibrosis patients

J. Mouton, A. Horrevorts, 1991, European Journal of Clinical Microbiology and Infectious Diseases.

Serum concentrations of amoxicillin in neonates during continuous intravenous infusion

T. Sprong, J. Mouton, C. Kramers, 2016, European Journal of Clinical Microbiology & Infectious Diseases.

Exploring colistin pharmacodynamics against Klebsiella pneumoniae: a need to revise current susceptibility breakpoints

A. Tsakris, S. Pournaras, G. Daikos, 2018, The Journal of antimicrobial chemotherapy.

Triple combination of meropenem, colistin and tigecycline was bactericidal in a dynamic model despite mere additive interactions in chequerboard assays against carbapenemase-producing Klebsiella pneumoniae isolates

S. Pournaras, G. Daikos, J. Meletiadis, 2018, The Journal of antimicrobial chemotherapy.

Targeting of Antibiotics in Bacterial Infections Using Pegylated Long-Circulating Liposomes

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Large-scale WGS of carbapenem-resistant Acinetobacter baumannii isolates reveals patterns of dissemination of ST clades associated with antibiotic resistance.

L. Leibovici, A. Keren-Paz, Y. Carmeli, 2022, Journal of Antimicrobial Chemotherapy.

Temocillin (6 g daily) in critically ill patients: continuous infusion versus three times daily administration.

P. Laterre, P. Tulkens, J. Mouton, 2015, The Journal of antimicrobial chemotherapy.

Protection against influenza A virus infection in mice by oral immunization with a polyvalent bacterial lysate.

J. Mouton, B. Lachmann, F. D. Beusenberg, 1991, International Journal of Immunopharmacology.

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs.

O. Cars, G. Drusano, H. Derendorf, 2002, International journal of antimicrobial agents.

Kucers' The Use of Antibiotics

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Serum Concentrations of Cefotaxime and its Metabolite Desacetyl-cefotaxime in Infants and Children During Continuous Infusion

J. Mouton, R. Bertels, G. Gerrits, 2008, Infection.

Urinary antibacterial activity of fosfomycin and nitrofurantoin at registered dosages in healthy volunteers.

A. Huttner, Wendy Kloezen, J. Mouton, 2019, International journal of antimicrobial agents.

MIC-based dose adjustment: facts and fables-authors' response.

J. Turnidge, G. Kahlmeter, R. Cantón, 2018, The Journal of antimicrobial chemotherapy.

Wild-type MIC distribution and epidemiological cut-off values in clinical Legionella pneumophila serogroup 1 isolates.

B. Diederen, J. Mouton, J. D. den Boer, 2012, Diagnostic microbiology and infectious disease.

Isolation of ciprofloxacin-resistant Legionella pneumophila in a patient with severe pneumonia.

C. Lück, B. Diederen, J. Mouton, 2014, The Journal of antimicrobial chemotherapy.

A New Marker of Echinocandin Activity in an In Vitro Pharmacokinetic/Pharmacodynamic Model Correlates with an Animal Model of Aspergillus fumigatus Infection

S. Pournaras, A. Tsakris, J. Meletiadis, 2018, Antimicrobial Agents and Chemotherapy.

Duration of antibiotic treatment: are even numbers odd?

J. G. van der Hoeven, A. Voss, E. Alp, 2005, The Journal of antimicrobial chemotherapy.

Vancomycin population pharmacokinetics in neonates

R. Schoemaker, J. Mouton, J. Anker, 2000, Clinical pharmacology and therapeutics.

Vancomycin and Administration Regimens

J. Anker, J. Mouton, M. Hoog, 2004 .

Letter to the editor (multiple letters)

J. Anker, L. Stolk, J. Mouton, 2003 .

Thoughts on "Population pharmacokinetics and relationship between demographic and clinical variables and pharmacokinetics of gentamicin in neonates".

J. N. van den Anker, M. de Hoog, J. Mouton, 2003, Therapeutic Drug Monitoring.

Polymorphisms in cytokine genes IL6, TNF, IL10, IL17A and IFNG influence susceptibility to complicated skin and skin structure infections

M. Oosting, M. Netea, I. Gyssens, 2014, European Journal of Clinical Microbiology & Infectious Diseases.

The Therapeutic Effect of Tigecycline, Unlike That of Ceftazidime, Is Not Influenced by whether the Klebsiella pneumoniae Strain Produces Extended-Spectrum β-Lactamases in Experimental Pneumonia in Rats

M. Kinzig, F. Sörgel, M. T. ten Kate, 2012, Antimicrobial Agents and Chemotherapy.

Why monitor peak vancomycin concentrations?

J. N. van den Anker, M. de Hoog, J. Mouton, 1995, Lancet.

Abnormal pharmacokinetics: the need for monitoring

J. Mouton, A. Horrevorts, 2006, European Journal of Clinical Microbiology and Infectious Diseases.

Hepatitis B transmission among heart transplant recipients: an underestimated risk?

A. Osterhaus, H. Verbrugh, M. Vos, 1996 .

Annals of Clinical Microbiology and Antimicrobials Open Access a Multi-center Blinded Study on the Efficiency of Phenotypic Screening Methods to Detect Glycopeptide Intermediately Susceptible Staphylococcus Aureus (gisa) and Heterogeneous Gisa (h-gisa)

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Spectrophotometric reading of EUCAST antifungal susceptibility testing of Aspergillus fumigatus.

M. Arendrup, P. Verweij, J. Meletiadis, 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

P. Tulkens, J. Mouton, R. Hens, 2008 .

Continuous versus intermittent infusion of temocillin , a directed spectrum penicillin for intensive care patients with nosocomial pneumonia : stability , compatibility , population pharmacokinetic studies and breakpoint selection

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Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions.

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Tissue concentrations: do we ever learn?

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Method for Phenotypic Detection of Extended-Spectrum Beta-Lactamases in Enterobacter Species in the Routine Clinical Setting

B. Diederen, N. Arents, A. Fluit, 2011, Journal of Clinical Microbiology.

Ciprofloxacin in preterm neonates: case report and review of the literature

J. N. van den Anker, J. Mouton, H. Neijens, 1998, European Journal of Pediatrics.

In Vitro Activity of Ceftazidime-Avibactam Combination in In Vitro Checkerboard Assays

J. Mouton, W. Nichols, M. Melchers, 2014, Antimicrobial Agents and Chemotherapy.

Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink?

D. Livermore, T. Nichols, J. Mouton, 2010, The Journal of antimicrobial chemotherapy.

Reduction of Surgical-Site Infections in Cardiothoracic Surgery by Elimination of Nasal Carriage of Staphylococcus aureus

H. Verbrugh, A. Maat, J. Mouton, 1996, Infection Control & Hospital Epidemiology.

Oral immunization with a polyvalent bacterial lysate can reduce mortality by infection with S. pneumoniae or influenza A in mice.

J. Mouton, B. Lachmann, R. Tenbrinck, 1990, Pneumologie.

Oral immunization with bacterial lysate against infection with Streptococcus pneumoniae in mice.

J. Mouton, B. Lachmann, R. Tenbrinck, 1990, Respiration; international review of thoracic diseases.

Pharmacokinetics and Target Attainment of Ceftobiprole in Asian and Non‐Asian Subjects

A. Schmitt-Hoffmann, J. Mouton, A. Muller, 2018, Clinical pharmacology in drug development.

Impact of cyp51A Mutations on the Pharmacokinetic and Pharmacodynamic Properties of Voriconazole in a Murine Model of Disseminated Aspergillosis

W. Melchers, P. Verweij, J. Mouton, 2010, Antimicrobial Agents and Chemotherapy.

Towards Rational Dosing Algorithms for Vancomycin in Neonates and Infants Based on Population Pharmacokinetic Modeling

J. N. van den Anker, C. Knibbe, Pyry A. J. Välitalo, 2015, Antimicrobial Agents and Chemotherapy.

Aerosol therapy in cystic fibrosis: A survey of 54 CF centers

H. Tiddens, J. D. de Jongste, J. Mouton, 2000, Pediatric pulmonology.

Direct molecular versus culture-based assessment of Gram-positive cocci in biopsies of patients with major abscesses and diabetic foot infections

J. Meis, I. Gyssens, F. Hagen, 2015, European Journal of Clinical Microbiology & Infectious Diseases.

Failure of Posaconazole Therapy in a Renal Transplant Patient with Invasive Aspergillosis Due to Aspergillus fumigatus with Attenuated Susceptibility to Posaconazole

W. Melchers, P. Verweij, J. Mouton, 2011, Antimicrobial Agents and Chemotherapy.

Tobramycin population pharmacokinetics in neonates *

R. Schoemaker, J. Mouton, J. Anker, 1997, Clinical pharmacology and therapeutics.

Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial.

L. Leibovici, Y. Carmeli, O. Zusman, 2018, The Lancet. Infectious diseases.