S. Hedtrich

发表

pH-Modulating Poly(ethylene glycol)/Alginate Hydrogel Dressings for the Treatment of Chronic Wounds.

A. Goepferich, F. Brandl, Julia Koehler, 2017, Macromolecular bioscience.

Crosstalk between core-multishell nanocarriers for cutaneous drug delivery and antigen-presenting cells of the skin.

A. Gruber, R. Haag, L. Mundhenk, 2018, Biomaterials.

Recent advances in topical delivery of proteins and peptides mediated by soft matter nanocarriers.

Sarah Hedtrich, W. Friess, S. Hedtrich, 2015, Biotechnology advances.

Polypeptide-corticosteroid conjugates as a topical treatment approach to psoriasis.

M. Vicent, S. Hedtrich, Marwa A. Sallam, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Sulfoxide-functionalized nanogels inspired by the skin penetration properties of DMSO.

E. Rühl, F. Rancan, S. Hedtrich, 2020, Biomaterials science.

Alkaline poly(ethylene glycol)-based hydrogels for a potential use as bioactive wound dressings.

A. Goepferich, F. Brandl, Julia Koehler, 2017, Journal of biomedical materials research. Part A.

TSLP as druggable target - a silver-lining for atopic diseases?

B. Page, S. Hedtrich, Zheng Tan, 2020, Pharmacology & therapeutics.

Histological and functional comparisons of four anatomical regions of porcine skin with human abdominal skin

S. Hedtrich, J. Plendl, K. Richardson, 2019, Anatomia, histologia, embryologia.

Impact of structural differences in hyperbranched polyglycerol–polyethylene glycol nanoparticles on dermal drug delivery and biocompatibility.

R. Haag, A. Luch, S Kumar, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Generation of full‐thickness skin equivalents using hair follicle‐derived primary human keratinocytes and fibroblasts

S. Hedtrich, A. Vogt, S. Kaessmeyer, 2018, Journal of tissue engineering and regenerative medicine.

Intradermal drug delivery by nanogel-peptide conjugates; specific and efficient transport of temoporfin.

R. Haag, F. Zabihi, H. Börner, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Breaking the Barrier - Potent Anti-Inflammatory Activity following Efficient Topical Delivery of Etanercept using Thermoresponsive Nanogels

M. Calderón, S. Hedtrich, B. Kleuser, 2018, Theranostics.

Human Pulmonary 3D Models For Translational Research

N. Suttorp, A. Hocke, S. Hippenstiel, 2017, Biotechnology journal.

Protein Corona Formation on Colloidal Polymeric Nanoparticles and Polymeric Nanogels: Impact on Cellular Uptake, Toxicity, Immunogenicity, and Drug Release Properties.

R. Haag, M. Calderón, R. Bodmeier, 2017, Biomacromolecules.

Stratum corneum targeting by dendritic core-multishell-nanocarriers in a mouse model of psoriasis.

A. Gruber, R. Haag, L. Mundhenk, 2017, Nanomedicine : nanotechnology, biology, and medicine.

Non-ionic PEG-Oligoglycerol Dendron Conjugated Nano-carriers for Transdermal Delivery.

Rashmi, R. Haag, B. Schade, 2020, International journal of pharmaceutics.

Hydrogels Containing Budesonide-Loaded Nanoparticles to Facilitate Percutaneous Absorption for Atopic Dermatitis Treatment Applications

D. D. de Araújo, L. Fraceto, R. D. de Lima, 2021, ACS Applied Polymer Materials.

Regenerative potential of adipocytes in hypertrophic scars is mediated by myofibroblast reprogramming

Lenie J. van den Broek, S. Hedtrich, C. Sachse, 2019, Journal of Molecular Medicine.

Influence of the skin barrier on the penetration of topically‐applied dexamethasone probed by soft X‐ray spectromicroscopy

I. Bykova, P. Schrade, S. Bachmann, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Impact of intercellular crosstalk between epidermal keratinocytes and dermal fibroblasts on skin homeostasis.

K. Vávrová, G. Erdmann, S. Hedtrich, 2020, Biochimica et biophysica acta. Molecular cell research.

Gene Delivery to the Skin – How Far Have We Come?

Ariel Huynh, D. Witzigmann, Q. Ain, 2020, Trends in Biotechnology.

Investigation of TEMPO partitioning in different skin models as measured by EPR spectroscopy - Insight into the stratum corneum.

M. Meinke, K. Vávrová, J. Lademann, 2019, Journal of magnetic resonance.

Insight into the redox status of inflammatory skin equivalents as determined by EPR spectroscopy.

M. Meinke, S. Hedtrich, C. Teutloff, 2019, Chemico-biological interactions.

Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels.

F. Schumacher, M. Calderón, J. Bergueiro, 2017, Nanoscale.

Development of biodegradable hyperbranched core-multishell nanocarriers for efficient topical drug delivery.

R. Haag, Wei Chen, Falko Neumann, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Core-multishell nanocarriers: Transport and release of dexamethasone probed by soft X-ray spectromicroscopy.

N. Kosugi, R. Haag, T. Ohigashi, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Hyperbranched glycerol-based core-amphiphilic branched shell nanotransporters for dermal drug delivery

R. Haag, Falko Neumann, A. Prasad, 2016 .

Serine Protease Mauritanicain from Euphorbia mauritanica and Phorbol-12-myristate-13-acetate Modulate the IL-8 Release in Fibroblasts and HaCaT Keratinocytes

M. Melzig, S. Hedtrich, Deborah Maus, 2018, Planta Medica.

Interactions of hyaluronic Acid with the skin and implications for the dermal delivery of biomacromolecules.

K. Vávrová, W. Friess, S. Hedtrich, 2015, Molecular pharmaceutics.

Hyaluronic Acid for Percutaneous Drug Delivery

W. Friess, S. Hedtrich, 2015 .

Small, Cationic Antifungal Proteins from Filamentous Fungi Inhibit Candida albicans Growth in 3D Skin Infection Models

L. Galgóczy, F. Marx, S. Hedtrich, 2022, Microbiology spectrum.

Supramolecular nanogels fabricated via host-guest molecular recognition as penetration enhancer for dermal drug delivery.

R. Haag, F. Zabihi, S. Hedtrich, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Inﬂuence of Th2 Cytokines on the Corniﬁed Envelope, Tight Junction Proteins, and b -Defensins in Filaggrin-Deﬁcient Skin Equivalents

L. Mundhenk, M. Schäfer-Korting, L. Wallmeyer, 2016 .

Synthesis of poly(lactide-co-glycerol) as a biodegradable and biocompatible polymer with high loading capacity for dermal drug delivery.

R. Haag, F. Schumacher, F. Zabihi, 2018, Nanoscale.

Rhamnolipids form drug‐loaded nanoparticles for dermal drug delivery

R. Haag, J. Rademann, E. Rühl, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Quantification and characterization of radical production in human, animal and 3D skin models during sun irradiation measured by EPR spectroscopy

M. Meinke, J. Lademann, L. Mundhenk, 2019, Free radical biology & medicine.

Synthesis of multiarm star copolymers based on polyglycerol cores with polylactide arms and their application as nanocarriers

R. Haag, M. Adeli, H. Namazi, 2015 .

Selective Probing of the Penetration of Dexamethasone into Human Skin by Soft X-ray Spectromicroscopy.

N. Kosugi, T. Ohigashi, P. Schrade, 2015, Analytical chemistry.

Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium

F. F. Sahle, F. Schumacher, R. Bodmeier, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

One-pot and gram-scale synthesis of biodegradable polyglycerols under ambient conditions: nanocarriers for intradermal drug delivery

R. Haag, F. Zabihi, A. N. Kharat, 2017 .

A Naked Eye‐Invisible Ratiometric Fluorescent Microneedle Tattoo for Real‐Time Monitoring of Inflammatory Skin Conditions

M. Bonmarin, S. Hedtrich, D. Brambilla, 2021, Advanced healthcare materials.

Tailored dendritic core-multishell nanocarriers for efficient dermal drug delivery: A systematic top-down approach from synthesis to preclinical testing.

Florian Paulus, Emanuel Fleige, Nan Zhang, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Transglutaminase 1 Replacement Therapy Successfully Mitigates the Autosomal Recessive Congenital Ichthyosis Phenotype in Full-Thickness Skin Disease Equivalents.

H. Hennies, S. Hedtrich, K. Eckl, 2019, The Journal of investigative dermatology.

Critical parameters for the controlled synthesis of nanogels suitable for temperature-triggered protein delivery.

M. Calderón, Mrityunjoy Kar, S. Wedepohl, 2019, Materials science & engineering. C, Materials for biological applications.

Thermosensitive dendritic polyglycerol-based nanogels for cutaneous delivery of biomacromolecules.

H. Hennies, M. Calderón, W. Friess, 2015, Nanomedicine : nanotechnology, biology, and medicine.

COVID-19 highlights the model dilemma in biomedical research

A. Hocke, S. Hedtrich, Partho P. Adhikary, 2021, Nature Reviews Materials.

TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents

A. Gruber, K. Vávrová, K. Dietert, 2017, Scientific Reports.

Ethyl cellulose nanocarriers and nanocrystals differentially deliver dexamethasone into intact, tape-stripped or sodium lauryl sulfate-exposed ex vivo human skin - assessment by intradermal microdialysis and extraction from the different skin layers.

F. Schumacher, M. Colombo, R. Bodmeier, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Effect of Delivery Platforms Structure on the Epidermal Antigen Transport for Topical Vaccination.

M. Calderón, Mrityunjoy Kar, L. Gugliotta, 2018, Biomacromolecules.

Alternatives to animal testing in basic and preclinical research of atopic dermatitis

S. Hedtrich, M. Jevtić, Frida Gorreja, 2018, Experimental dermatology.

Development of a Perfusion Platform for Dynamic Cultivation of in vitro Skin Models

W. Friess, S. Hedtrich, Kay Strüver, 2017, Skin Pharmacology and Physiology.

Biocompatibility and characterization of polyglycerol-based thermoresponsive nanogels designed as novel drug-delivery systems and their intracellular localization in keratinocytes

F. Schumacher, M. Calderón, N. Zhang, 2017, Nanotoxicology.

Beyond Ca2+ signalling: the role of TRPV3 in the transport of NH4+

F. Stumpff, S. Hedtrich, H. Liebe, 2021, Pflügers Archiv - European Journal of Physiology.

The effect of endothelialization on the epidermal differentiation in human three-dimensional skin constructs - A morphological study.

L. Wallmeyer, S. Hedtrich, J. Plendl, 2015, Clinical hemorheology and microcirculation.

Characterization of an ester-based core-multishell (CMS) nanocarrier for the topical application at the oral mucosa

R. Haag, K. Danker, H. Dommisch, 2021, Clinical Oral Investigations.

Stimulation of PPARα normalizes the skin lipid ratio and improves the skin barrier of normal and filaggrin deficient reconstructed skin.

K. Vávrová, L. Wallmeyer, S. Hedtrich, 2015, Journal of dermatological science.

Feasibility study for intraepidermal delivery of proteins using a solid microneedle array.

Sarah Hedtrich, W. Friess, S. Hedtrich, 2015, International journal of pharmaceutics.

Human disease models in drug development

S. Hedtrich, Anna Loewa, James J. Feng, 2023, Nature Reviews Bioengineering.

Preclinical Testing of Dendritic Core-Multishell Nanoparticles in Inflammatory Skin Equivalents.

A. Hocke, E. Fleige, M. Schäfer-Korting, 2022, Molecular pharmaceutics.

Lyophilization of Synthetic Gene Carriers.

J. Kasper, W. Friess, S. Hedtrich, 2019, Methods in molecular biology.

Specific uptake mechanisms of well‐tolerated thermoresponsive polyglycerol‐based nanogels in antigen‐presenting cells of the skin

M. Calderón, Falko Neumann, Nan Ma, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The Delivery Challenge of Genome Editing in Human Epithelia

Sarah Hedtrich, Marcelo Calderón, M. Calderón, 2021, Advanced healthcare materials.

Influence of Th2 Cytokines on the Cornified Envelope, Tight Junction Proteins, and ß-Defensins in Filaggrin-Deficient Skin Equivalents.

Monika Schäfer-Korting, Sarah Hedtrich, L. Mundhenk, 2016, The Journal of investigative dermatology.

EXTRACELLULAR MATRIX REMODELING IN ATOPIC DERMATITIS HARNESSES THE ONSET OF AN ASTHMATIC PHENOTYPE AND IS A POTENTIAL CONTRIBUTOR TO THE ATOPIC MARCH

A. Gruber, D. Beule, A. Thiel, 2022, medRxiv.

TITLE: EXTRACELLULAR MATRIX REMODELING IN ATOPIC DERMATITIS HAR- 1 NESSES THE ONSET OF AN ASTHMATIC PHENOTYPE AND IS A POTENTIAL CON-

A. Gruber, D. Beule, A. Thiel, 2022 .

3D organ models—Revolution in pharmacological research?

Sarah Hedtrich, Andreas Hocke, Marie Weinhart, 2018, Pharmacological Research.

S. Hedtrich, James J. Feng, 2022, Lab on a Chip.

TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents