R. Kreiling

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Evaluating the sensitization potential of surfactants: integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach.

Reinhard Kreiling, Nicholas Ball, Annette Mehling, 2011, Regulatory toxicology and pharmacology : RTP.

A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping).

Reinhard Kreiling, Robert Landsiedel, Wendel Wohlleben, 2015, Regulatory toxicology and pharmacology : RTP.

Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

Valérie Zuang, George Loizou, Andrew Worth, 2011, Archives of Toxicology.

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

Wolfgang Moritz, Wiebke Albrecht, Tim Brecklinghaus, 2019, Archives of Toxicology.

In chemico, in vitro and in vivo comparison of the skin sensitizing potential of eight unsaturated and one saturated lipid compounds

T. Broschard, U. Sauer, D. Eigler, 2017, Regulatory toxicology and pharmacology : RTP.

Toxicity testing of poorly soluble particles, lung overload and lung cancer

R. Bevan, D. Warheit, R. Kreiling, 2018, Regulatory toxicology and pharmacology : RTP.

Validation study of alternatives to the Draize eye irritation test in Germany: Cytotoxicity testing and HET-CAM test with 136 industrial chemicals.

M Liebsch, I Gerner, H Spielmann, 1993, Toxicology in vitro : an international journal published in association with BIBRA.

3.3. Eye Irritation

A. Worth, T. Seidle, P. Vanparys, 2005 .

The grouping and assessment strategy for organic pigments (GRAPE): Scientific evidence to facilitate regulatory decision-making.

U. Sauer, R. Kreiling, 2019, Regulatory toxicology and pharmacology : RTP.

Species differences in butadiene metabolism between mice and rats evaluated by inhalation pharmacokinetics

H. Bolt, J. Filser, R. Kreiling, 1986, Archives of Toxicology.

Eye irritation.

T. Seidle, P. Vanparys, L. Bruner, 2021, Alternatives to laboratory animals : ATLA.

Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.

M. Cronin, H. Clewell, E. Mombelli, 2022, Regulatory toxicology and pharmacology : RTP.

Relevance of the rat lung tumor response to particle overload for human risk assessment-Update and interpretation of new data since ILSI 2000.

D. Warheit, R. Kreiling, L. Levy, 2016, Toxicology.

Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients

S. H. Bennekou, V. Rogiers, K. Boekelheide, 2021, Regulatory toxicology and pharmacology : RTP.

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

J. Rahnenführer, K. Edlund, L. Kuepfer, 2019, Archives of Toxicology.

Inhalation pharmacokinetics of 1,3-butadiene and 1,2-epoxybutene-3 in rats and mice.

H. Bolt, J. Filser, R. Kreiling, 1990, Environmental health perspectives.

Results of a Validation Study in Germany on Two in Vitro Alternatives to the Draize Eye Irritation Test, the HET-CAM Test and the 3T3 NRU Cytotoxicity Test

Reinhard Kreiling, Hermann-Georg Holzhütter, Horst Spielmann, 1996 .

Comparative testing for the identification of skin-sensitizing potentials of nonionic sugar lipid surfactants.

Reinhard Kreiling, Nicholas Ball, Annette Mehling, 2010, Regulatory toxicology and pharmacology : RTP.

Continuing Animal Tests on Cosmetic Ingredients for REACH in the EU.

C. Rovida, T. Hartung, R. Kreiling, 2021, ALTEX.

Eye irritation: Reference chemicals data bank.

D M Bagley, P. Botham, R. Lewis, 1992, Toxicology in vitro : an international journal published in association with BIBRA.

Comparison of the skin sensitizing potential of unsaturated compounds as assessed by the murine local lymph node assay (LLNA) and the guinea pig maximization test (GPMT).

M. S. Lee, A. Wendel, D. Eigler, 2008, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Principles underpinning the use of new methodologies in the risk assessment of cosmetic ingredients

Reinhard Kreiling, Akihiko Hirose, Andrea Richarz, 2018, Computational Toxicology.

Case studies putting the decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping) into practice.

Reinhard Kreiling, Robert Landsiedel, Wendel Wohlleben, 2016, Regulatory toxicology and pharmacology : RTP.

Depletion of hepatic non-protein sulfhydryl content during exposure of rats and mice to butadiene.

H. Bolt, R. Kreiling, R. Laib, 1988, Toxicology letters.

Inhalation pharmacokinetics of 1,2-epoxybutene-3 reveal species differences between rats and mice sensitive to butadiene-induced carcinogenesis

H. Bolt, J. Filser, R. Kreiling, 2004, Archives of Toxicology.

Species Differences in Pharmacokinetics, Metabolism, and DNA Binding of Inhaled 1,3-Butadiene

S. Deutschmann, R. Kreiling, R. Laib, 1989 .

Alkylation of nuclear proteins and DNA after exposure of rats and mice to [1,4-14C]1,3-butadiene.

H. Bolt, R. Kreiling, R. Laib, 1986, Toxicology letters.

A critical appraisal of existing concepts for the grouping of nanomaterials.

Reinhard Kreiling, Robert Landsiedel, Thomas Petry, 2014, Regulatory toxicology and pharmacology : RTP.

Linking LRI AMBIT chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation

Reinhard Kreiling, Qiang Li, V. Koch, 2016 .

Efficacy of ozone in eradication of Legionella pneumophila from hospital plumbing fixtures

P. Edelstein, R. Kreiling, R. Whittaker, 1982, Applied and environmental microbiology.

Application of grouping and read-across for the evaluation of parabens of different chain lengths with a particular focus on endocrine properties

U. Sauer, R. Kreiling, S. Fayyaz, 2021, Archives of Toxicology.

Interlaboratory assessment of alternatives to the Draize eye irritation test in Germany.

I Gerner, H Spielmann, W Steiling, 1991, Toxicology in vitro : an international journal published in association with BIBRA.

Effect of proteins on availability of zinc II. Bioavailability of zinc from casein and whey protein — retention study in young rats

G. Harzer, R. Kreiling, H. Daniel, 1986, Zeitschrift für Ernährungswissenschaft.

Application of a weight of evidence approach to assessing discordant sensitisation datasets: implications for REACH.

Reinhard Kreiling, Nicholas Ball, David Basketter, 2009, Regulatory toxicology and pharmacology : RTP.

Eye irritation: Reference chemicals data bank

P. Botham, R. Lewis, R. Kreiling, 1992 .

Evaluating the sensitization potential of surfactants: integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach.

A. Natsch, R. Emter, N. Ball, 2011, Regulatory toxicology and pharmacology : RTP.