A. F. Kotzé

发表

Effect of the Type of Base and Number of Reaction Steps on the Degree of Quaternization and Molecular Weight of N-Trimethyl Chitosan Chloride

J. Hamman, A. F. Kotzé, J. H. Hamman, 2001, Drug development and industrial pharmacy.

In vivo/in vitro pharmacokinetic and pharmacodynamic study of spray-dried poly-(dl-lactic-co-glycolic) acid nanoparticles encapsulating rifampicin and isoniazid.

A. Lenaerts, H. Swai, A. F. Kotzé, 2013, International journal of pharmaceutics.

CHITOSAN AND CHITOSAN DERIVATIVES AS ABSORPTION ENHANCERS FOR PEPTIDE DRUGS ACROSS MUCOSAL EPITHELIA

H. Junginger, C. Lehr, M. Thanou, 1999 .

Preparation and NMR characterization of highly substitutedN-trimethyl chitosan chloride

J. Brussee, H. Junginger, A. Sieval, 1998 .

Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal caco-2 cell monolayers.

H. Junginger, M. Thanou, A. G. de Boer, 2000, Journal of controlled release : official journal of the Controlled Release Society.

Beneficial Pharmacokinetic Drug Interactions: A Tool to Improve the Bioavailability of Poorly Permeable Drugs

J. Hamman, A. F. Kotzé, J. D. Steyn, 2018, Pharmaceutics.

Pheroid™ Vesicles and Microsponges for Nasal Delivery of Biopharmaceuticals

A. F. Kotzé, L. H. Plessis, L. Plessis, 2014 .

Mucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro

H. Junginger, C. Lehr, A. Boer, 1997 .

Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2).

H. Junginger, M. Thanou, A. F. Kotzé, 1999, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Safe Mucosal Penetration Enhancers: A Fiction?: Polymers as Absorption Enhancers for Transmucosal Drug Delivery

H. Junginger, M. Thanou, A. F. Kotzé, 2000 .

Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: in vitro evaluation in intestinal epithelial cells (Caco-2).

H. Junginger, M. Thanou, A. G. de Boer, 1999, Journal of pharmaceutical sciences.

Chitosans for enhanced delivery of therapeutic peptides across intestinal epithelia: in vitro evaluation in Caco-2 cell monolayers

H. Junginger, A. Boer, A. F. Kotzé, 1997 .

Size characterization of Pheroid TM formulations and liposomes

A. F. Kotzé, L. H. Plessis, C. Slabbert, 2013 .

Nasal and rectal delivery of insulin with chitosan and N-trimethyl chitosan chloride

H. Junginger, A. F. Kotzé, L. D. du Plessis, 2010, Drug delivery.

Low molecular weight quaternised chitosan (11): in vitro assessment of absorption enhancing properties.

J. Hamman, J. Steenekamp, A. F. Kotzé, 2006, Die Pharmazie.

N-trimethyl chitosan chloride as absorption enhancer in oral peptide drug delivery. Development and characterization of minitablet and granule formulations.

H. Junginger, A. F. Kotzé, J. Verhoef, 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Low molecular weight quaternised chitosan (I): synthesis and characterisation.

T. Govender, A. F. Kotzé, D. Snyman, 2003, Die Pharmazie.

N-Trimethyl Chitosan Chloride: Optimum Degree of Quaternization for Drug Absorption Enhancement Across Epithelial Cells

J. Hamman, A. F. Kotzé, C. Schultz, 2003, Drug development and industrial pharmacy.

Intestinal paracellular permeation enhancement with quaternised chitosan: in situ and in vitro evaluation.

J. Hamman, A. F. Kotzé, C. Jonker, 2002, International journal of pharmaceutics.

Synthesis and evaluation of the mucoadhesivity of a CD-chitosan derivative.

J. P. Venter, R. Auzély-Velty, M. Rinaudo, 2006, International journal of pharmaceutics.

Effect of moisture content, temperature and exposure time on the physical stability of chitosan powder and tablets

J. Steenekamp, A. Marais, A. F. Kotzé, 2014, Drug development and industrial pharmacy.

The relationship between the absolute molecular weight and the degree of quaternisation of N-trimethyl chitosan chloride

J. Hamman, A. F. Kotzé, J. S. Kotze, 2002 .

Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs.

H E Junginger, H. Junginger, A. F. Kotzé, 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Evaluation of the Mucoadhesive Properties of N-Trimethyl Chitosan Chloride

J. Hamman, A. F. Kotzé, D. Snyman, 2003, Drug development and industrial pharmacy.

Absorption of the novel artemisinin derivatives artemisone and artemiside: potential application of Pheroid™ technology.

Peter J. Smith, L. Wiesner, A. F. Kotzé, 2011, International journal of pharmaceutics.

Effect of the degree of quaternisation of N-trimethyl chitosan chloride on absorption enhancement: in vivo evaluation in rat nasal epithelia.

J. Hamman, A. F. Kotzé, M. Stander, 2002, International journal of pharmaceutics.

Comparison of the effect of different chitosan salts and N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2).

H. Junginger, B. Boer, A. G. de Boer, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Oral Delivery of Peptide Drugs

Josias H. Hamman, J. Hamman, A. F. Kotzé, 2012, BioDrugs.

Enhancement of nasal and intestinal calcitonin delivery by the novel Pheroid fatty acid based delivery system, and by N-trimethyl chitosan chloride.

A. F. Kotzé, L. D. du Plessis, J. Lubbe, 2010, International journal of pharmaceutics.

Chitosan for enhanced intestinal permeability: prospects for derivatives soluble in neutral and basic environments.

H. Junginger, A. G. de Boer, A. F. Kotzé, 1999, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Enhancement of microbiological safety levels of aseptically admixed total parenteral nutrition solutions through low‐dose gamma irradiation

H. Koornhof, A. F. Kotzé, M. Isaäcson, 1994, Journal of clinical pharmacy and therapeutics.

Oral delivery of peptide drugs: barriers and developments.

J. Hamman, A. F. Kotzé, Josias H Hamman, 2005, BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy.

Formulation and evaluation of Pheroid vesicles containing mefloquine for the treatment of malaria

L. Wiesner, A. F. Kotzé, L. Plessis, 2014, The Journal of pharmacy and pharmacology.

Intestinal Drug Absorption Enhancers: Synergistic Effects of Combinations

J. Hamman, A. F. Kotzé, G. Enslin, 2008 .

Evaluation of the physical properties and stability of two lipid drug delivery systems containing mefloquine.

A. F. Kotzé, C. Slabbert, L. Plessis, 2011, International journal of pharmaceutics.

In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum

A. F. Kotzé, A. V. Niekerk, L. Plessis, 2012, The Journal of Antibiotics.

Enhancement of nasal and intestinal calcitonin delivery by the novel Pheroid fatty acid based delivery system, and by N-trimethyl chitosan chloride.

A. F. Kotzé, L. D. du Plessis, J. Lubbe, 2010, International journal of pharmaceutics.

Effect of moisture content, temperature and exposure time on the physical stability of chitosan powder and tablets

J. Steenekamp, A. Marais, A. F. Kotzé, 2014, Drug Development and Industrial Pharmacy.