M. Osame

K. Arimura, M. Nakagawa, S. Izumo, 1996, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Association of a particular amino acid sequence of the HLA‐DR β1 chain with HTLV‐I‐associated myelopathy

T. Tabira, K. Tokunaga, M. Nishizawa, 1990, European journal of immunology.

HTLV-1–associated myelopathy/tropical spastic paraparesis with pseudohypoparathyroidism

M. Osame, Y. Yoshida, N. Machigashira, 2001, Neurology.

HTLV‐I viral escape and host genetic changes in the development of adult T cell leukemia

K. Arimura, S. Izumo, M. Osame, 2006, International journal of cancer.

Fibronectin receptor reduction in skin and fibroblasts of patients with Ullrich's disease

M. Osame, I. Higuchi, A. Saito, 2002, Muscle & nerve.

Chronic sensory ataxic neuropathy and ophthalmoplegia with oculomotor nerve hypertrophy associated with IgM antibodies against gangliosides containing disialosyl groups.

K. Arimura, M. Osame, F. Umehara, 1997, Journal of neurology, neurosurgery, and psychiatry.

Different manners of sarcoglycan expression in genetically proven α-sarcoglycan deficiency and γ-sarcoglycan deficiency

K. Arimura, M. Nakagawa, M. Osame, 1998, Acta Neuropathologica.

Different manners of sarcoglycan expression in genetically proven alpha-sarcoglycan deficiency and gamma-sarcoglycan deficiency.

K. Arimura, M. Nakagawa, M. Osame, 1998, Acta Neuropathologica.

Miyoshi myopathy patients with novel 5' splicing donor site mutations showed different dysferlin immunostaining at the sarcolemma

M. Nakagawa, Toshiaki Takahashi, M. Aoki, 2002, Acta Neuropathologica.

In vivo induction of human immunodeficiency virus type 1 entry into nucleus-free cells by CD4 gene transfer to hematopoietic stem cells: a hypothetical possible strategy for therapeutic intervention.

W. Hall, M. Osame, S. Ijichi, 2002, Medical hypotheses.

[Chronic interstitial pneumonia and crescentic glomerulonephritis associated with perinuclear antineutrophil cytoplasmic antibodies].

M. Osame, K. Mizuno, W. Matsuyama, 1997, Nihon Kyobu Shikkan Gakkai zasshi.

Type II muscle fibers are stained by anti-Fas antibody

M. Nakagawa, M. Osame, I. Higuchi, 1995, Journal of the Neurological Sciences.

Immunological abnormality in patients with lysinuric protein intolerance

T. Moritoyo, M. Osame, Y. Yoshida, 1995, Journal of the Neurological Sciences.

Eosinophilic pneumonia with eosinophilic gastroenteritis.

K. Arimura, M. Osame, I. Higashimoto, 1999, Internal medicine.

Abnormal expression of proteoglycans in Ullrich's disease with collagen VI deficiency

K. Arimura, M. Osame, I. Higuchi, 2006, Muscle & nerve.

Vacuolar myositis with expression of both MHC class I and class II antigens on skeletal muscle fibers

M. Nerenberg, K. Arimura, M. Osame, 1991, Journal of the Neurological Sciences.

Myocardial patchy staining of dystrophin in Becker's muscular dystrophy associated with cardiomyopathy.

M. Osame, I. Higuchi, A. Kisanuki, 1992, American heart journal.

Human T-cell lymphotropic virus type I and neurological diseases

M. Nagai, M. Osame, 2003, Journal of NeuroVirology.

Pathological mechanisms of human T-cell lymphotropic virus type I-associated myelopathy (HAM/TSP)

M. Osame, 2011, Journal of NeuroVirology.

Diversity of intrathecal antibody synthesis against HTLV-I and its relation to HTLV-I associated myelopathy

T. Fujiyoshi, S. Yashiki, S. Sonoda, 1996, Journal of Neurology.

Suppression of lymphocyte spontaneous proliferative response by proteolipid protein peptide in patients with HAM/TSP

T. Tabira, T. Yamamura, M. Osame, 1994, Neurochemical Research.

HTLV-I and HTLV-II

M. Osame, 2004 .

Phylogenetic subgroups of human T cell lymphotropic virus (HTLV) type I in the tax gene and their association with different risks for HTLV-I-associated myelopathy/tropical spastic paraparesis.

M. Nakagawa, M. Yamashita, S. Izumo, 2000, The Journal of infectious diseases.

Perivascular T cells are infected with HTLV-I in the spinal cord lesions with HTLV-I-associated myelopathy/tropical spastic paraparesis: double staining of immunohistochemistry and polymerase chain reaction in situ hybridization

E. Sato, Y. Isashiki, S. Izumo, 1998, Acta Neuropathologica.

In vitro virus propagation and high cellular responsiveness to the infected cells in patients with HTLV-I-associated myelopathy (HAM/TSP)

W. Hall, Y. Yamano, M. Nagai, 1997, Journal of the Neurological Sciences.

Antibody reactivities to tumor‐suppressor protein p53 and HTLV‐I Tof, Rex and Tax in HTLV‐I‐infected people with differing clinical status

M. Osame, Yi‐Ming Arthur Chen, Jeou‐Yuan Chen, 1997, International journal of cancer.

Mutation rates in LTR of HTLV-1 in HAM/TSP patients and the carriers are similarly high to Tax/Rex-coding sequence.

M. Yoshida, S. Izumo, M. Osame, 1996, Journal of neurovirology.

LATE PHASE SPONTANEOUS PROLIFERATION OF CULTURED PERIPHERAL BLOOD LYMPHOCYTES ASSOCIATED WITH HTLV-I INFECTION

W. Hall, M. Nagai, M. Osame, 1996 .

Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis.

K. Arimura, M. Nakagawa, S. Izumo, 1996, Journal of neurovirology.

Frequent mutation in pX region of HTLV-1 is observed in HAM/TSP patients, but is not specifically associated with the central nervous system lesions.

M. Yoshida, S. Sonoda, S. Izumo, 1995, Journal of neurovirology.

Cell surface phenotype of in vitro proliferating lymphocytes in HTLV-I-associated myelopathy (HAM/TSP)

S. Yashiki, S. Sonoda, M. Osame, 1992, Journal of Neuroimmunology.

Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in HTLV-I-associated myelopathy.

Y. Okada, N. Fujimoto, S. Izumo, 1998, Journal of neuropathology and experimental neurology.

Longer dinucleotide repeat polymorphism in matrix metalloproteinase-9 (MMP-9) gene promoter which correlates with higher HTLV-I Tax mediated transcriptional activity influences the risk of HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP)

K. Arimura, S. Izumo, M. Osame, 2004, Journal of Neuroimmunology.

Iodine-123 iodobenzofuran (I-123 IBF) SPECT in patients with parkinsonism

M. Nakajo, M. Osame, A. Tani, 1999, Annals of nuclear medicine.

Clinical symptoms and the odds of human T-cell lymphotropic virus type 1-associated myelopathy/ tropical spastic paraparesis (HAM/TSP) in healthy virus carriers: Application of best-fit logistic regression equation based on host genotype, age, and provirus load

K. Arimura, S. Izumo, M. Osame, 2006, Journal of NeuroVirology.

Possible HLA association with susceptibility to HTLV-1 tropical spastic paraparesis in Israel in Iranian Jews as compared to HTLV 1-associated myelopathy in Japan.

A. Achiron, Y. Sidi, I. Kochba, 1996, Tissue antigens.

PET scan study on the dopaminergic system in a Japanese patient with hereditary progressive dystonia (Segawa's disease). Case report.

B. Snow, D. Calne, M. Nomoto, 1993, Advances in neurology.

Human T-cell leukemia virus type-1 (HTLV-1) Tax is expressed at the same level in infected cells of HTLV-1-associated myelopathy or tropical spastic paraparesis patients as in asymptomatic carriers but at a lower level in adult T-cell leukemia cells.

M. Yoshida, M. Osame, R. Kubota, 1995, Blood.

Frequent clonal proliferation of human T-cell leukemia virus type 1 (HTLV-1)-infected T cells in HTLV-1-associated myelopathy (HAM-TSP).

M. Yoshida, J. Fujisawa, S. Sonoda, 1992, Blood.

Pathological changes in skeletal muscle in HTLV-I-associated myelopathy

K. Arimura, M. Osame, I. Higuchi, 1992, Journal of the Neurological Sciences.

Failure to detect HTLV‐I by in situ hybridization in the biopsied muscles of viral carriers with polymyositis

M. Nerenberg, K. Tajima, M. Osame, 1992, Muscle & nerve.

M. Nakagawa, M. Osame, I. Higuchi, 1994, Internal medicine.

Killer cell immunoglobulin‐like receptor/3DL2 expression in adult T‐cell leukaemia

K. Arimura, M. Osame, R. Kubota, 2007, British journal of haematology.

Serum amyloid A and P protein levels are lowered by dextran sulfate cellulose low-density lipoprotein apheresis.

M. Osame, M. Kuriyama, J. Fujiyama, 1998, Artificial organs.

Lymphocyte α-Glucosidase in Late-Onset Glycogenosis Type II

T. Kohriyama, M. Osame, R. Hiwatari, 1989 .

Nasu-Hakola disease (membranous lipodystrophy) Clinical, histopathological and biochemical studies of three cases

I. Kitajima, T. Suganuma, S. Izumo, 1989, Journal of the Neurological Sciences.

OCCULT DIFFUSE INVOLVEMENT OF SUPRATENTORIAL WHITE MATTER DETECTED BY MAGNETIC RESONANCE IMAGING IN HTLV-I CARRIERS

I. Maruyama, M. Osame, S. Ijichi, 1994 .

An autopsy case of peripheral neuroepithelioma in posterior mediastinum with p53 point mutation.

M. Nakagawa, M. Osame, K. Mizuno, 1998, Internal medicine.

Clinical manifestation of human T-cell lymphotropic virus type-I-associated myelopathy and vesicopathy.

A. Imamura, Y. Ohi, M. Osame, 1991, Urologia internationalis.

Neuropathology of HTLV‐I‐Associated Myelopathy—A Report of Two Autopsy Cases—

S. Izumo, M. Osame, I. Higuchi, 1992, Acta paediatrica Japonica : Overseas edition.

Geographical subtypes demonstrated by RFLP following PCR in the LTR region of HTLV-I.

G. de Thé, F. Pelloquin, S. Sonoda, 1992, AIDS research and human retroviruses.

Elevated levels of interleukin-6 in serum and cerebrospinal fluid of HTLV-I-associated myelopathy/tropical spastic paraparesis

A. Ogata, T. Kishimoto, H. Tagoh, 1990, Journal of the Neurological Sciences.

Activated T lymphocytes in cerebrospinal fluid of patients with HTLV-I-associated myelopathy (HAM/TSP)

S. Sonoda, S. Izumo, M. Osame, 1989, Journal of Neuroimmunology.

Symposium on viral infections in medicine. 2. The history of discovery and clinicoepidemiology of HTLV-I-associated myelopathy(HAM).

M. Osame, A. Igata, 1988 .

Clinical electrophysiologic studies of HTLV-I-associated myelopathy.

K. Arimura, R. Rosales, M. Osame, 1987, Archives of neurology.

Immunohistochemical demonstration of acid α-glucosidase in muscle in Pompe's disease

I. Matsuda, S. Fukuda, M. Osame, 1983, The Histochemical Journal.

Relative prevalence and risk factors of HTLV-I and HTLV-II infection in US blood donors

S. Kleinman, I. Chen, D. Smith, 1991, The Lancet.

Skeletal muscle abnormalities in two patients with dystonia

K. Arimura, M. Osame, I. Higuchi, 2002, Acta Neuropathologica.

IgM‐containing fraction suppressed voltage‐gated potassium channels in acquired neuromyotonia

K. Arimura, M. Kameyama, M. Osame, 2006, Acta neurologica Scandinavica.

Sequence analysis of human T cell lymphotropic virus type I (HTLV-I) Env genes amplified from central nervous system tissues of patients with HTLV-I-associated myelopathy or leukemia.

A. Haase, E. Sato, S. Izumo, 1995, Microbial pathogenesis.

Bronchiectasis with myeloperoxidase antineutrophil cytoplasmic antibody and bactericidal/permeability-increasing protein antineutrophil cytoplasmic antibody.

M. Osame, W. Matsuyama, F. Iwami, 1999, Internal medicine.

Benign monoclonal T cell proliferation in HTLV-I infection.

M. Osame, S. Ijichi, 1993, Medical hypotheses.

Adult T‐cell leukemia predominantly involving exocrine glands

M. Osame, I. Higuchi, M. Saito, 2004, European journal of haematology.

STUDY OF CYTOCHROME C OXIDASE WITH A MONOCLONAL ANTIBODY IN MITOCHONDRIAL MYOPATHY

M. Osame, I. Higuchi, H. Fukunaga, 2009 .

Experimental germanium myopathy

M. Nakagawa, S. Izumo, M. Osame, 2004, Acta Neuropathologica.

Experimental simvastatin-induced myopathy in rabbits

K. Arimura, M. Nakagawa, M. Osame, 1992, Journal of the Neurological Sciences.

IMMUNOHISTOCHEMICAL STUDY OF CYTOCHROME COXIDASE WITH A MONOCLONAL ANTIBODY IN MITOCHONDRIAL MYOPATHY

M. Nakagawa, M. Osame, I. Higuchi, 1988 .

Limited sequence divergence of HTLV-I of Indian HAM/TSP patients from a prototype Japanese isolate.

M. Yoshida, J. Fujisawa, M. Osame, 1993, AIDS research and human retroviruses.

Inhibitory effect of maternal antibody on mother‐to‐child transmission of human T‐lymphotropic virus type I

T. Takezaki, Y. Nagata, N. Mueller, 1991, International journal of cancer.

Polyneuropathy with minifascicle formation in a patient with 46XY mixed gonadal dysgenesis

K. Arimura, M. Osame, F. Umehara, 1999, Acta Neuropathologica.

The risk of development of HTLV-I-associated myelopathy/tropical spastic paraparesis among persons infected with HTLV-I.

R. Janssen, R. Khabbaz, J. Kaplan, 1990, Journal of acquired immune deficiency syndromes.

HTLV-I ASSOCIATED MYELOPATHY, A NEW CLINICAL ENTITY

Mitsuhiro Osame, Akihiro Igata, Naomi Ijichi, 1986, The Lancet.

Increased frequency of CD4+T cells expressing fractalkine receptor CX3CR1 in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), but its AIDS susceptible polymorphisms are not associated with the disease

K. Arimura, Y. Ohara, S. Izumo, 2008, Journal of the Neurological Sciences.

Zidovudine plus lamivudine in Human T-Lymphotropic Virus type-I-associated myelopathy: a randomised trial

P. Rudge, J. Weber, A. Babiker, 2006, Retrovirology.

Human T cell lymphotropic virus type I (HTLV-I) p12I is dispensable for HTLV-I transmission and maintenance of infection in vivo.

S. Izumo, M. Osame, K. Usuku, 2004, AIDS research and human retroviruses.

A C77G point mutation in CD45 exon 4, which is associated with the development of multiple sclerosis and increased susceptibility to HIV‐1 infection, is undetectable in Japanese population

S. Izumo, M. Osame, M. Saito, 2003, European journal of neurology.

Human T-cell lymphotropic virus type I (HTLV-I)-related clinical and laboratory findings for HTLV-I-infected blood donors.

M. Nakagawa, S. Izumo, M. Osame, 2003, Journal of acquired immune deficiency syndromes.

The clinical and pathological features of peripheral neuropathy accompanied with HTLV-I associated myelopathy

S. Izumo, M. Osame, F. Umehara, 2003, Journal of the Neurological Sciences.

HTLV‐I‐associated myelopathy

S. Izumo, M. Osame, F. Umehara, 2000, Neuropathology : official journal of the Japanese Society of Neuropathology.

Histopathological analysis of four autopsy cases of HTLV-I-associated myelopathy/tropical spastic paraparesis: inflammatory changes occur simultaneously in the entire central nervous system

Y. Isashiki, T. Moritoyo, M. Osame, 2000, Acta Neuropathologica.

Muscular Power of Truncal Extension and Flexion in Patients with HAM

M. Osame, Y. Yoshida, H. Moriyama, 2000 .

Clinical course of HTLV-I-associated uveitis.

M. Nakagawa, N. Ohba, K. Nakao, 1999, Japanese journal of ophthalmology.

A rat model of human T lymphocyte virus type I (HTLV-I) infection: in situ detection of HTLV-I provirus DNA in microglia/macrophages in affected spinal cords of rats with HTLV-I-induced chronic progressive myeloneuropathy

H. Ikeda, T. Yoshiki, I. Yamashita, 1999, Acta Neuropathologica.

Interferon-alpha is effective in HTLV-I-associated myelopathy

Y. Itoyama, M. Nakagawa, S. Izumo, 1996, Neurology.

Human T-cell lymphotropic virus type-I (HTLV-I)-associated myelopathy/tropical spastic paraparesis with acute type of adult T-cell leukemia.

S. Izumo, M. Osame, M. Tara, 1995, Internal medicine.

Diseases among men living in human T-lymphotropic virus type I endemic areas in Japan.

K. Arimura, M. Osame, T. Matsuzaki, 1993, Internal medicine.

Immunohistochemical characteristics of polymyositis in patients with HTLV‐1–associated myelopathy and HTLV‐I carriers

M. Osame, I. Higuchi, M. Inose, 1993, Muscle & nerve.

Arthritis in a human T lymphotropic virus type I (HTLV-I) carrier.

I. Maruyama, S. Sonoda, M. Osame, 1990, Annals of the rheumatic diseases.

Polyarthritis in human T lymphotropic virus type I-associated myelopathy.

I. Maruyama, I. Kitajima, M. Osame, 1989, Arthritis and rheumatism.

Retinal vasculitis in human T-lymphotropic virus type I associated myelopathy.

H. Inomata, K. Sasaki, M. Osame, 1989, The British journal of ophthalmology.

In vitro modulation of lymphocyte proliferation by prednisolone and interferon-α in patients with HTLV-I-associated myelopathy (HAM)

I. Maruyama, S. Sonoda, S. Izumo, 1989, Journal of Neuroimmunology.

Electroencephalographic abnormalities in human T-cell lymphotropic virus type I-associated myelopathy.

K. Arimura, M. Osame, Y. Arimura, 1989, Archives of neurology.

[Viral infections in medicine. 2. The history of discovery and clinico-epidemiology of HTLV-I-associated myelopathy (HAM)].

M. Osame, A. Igata, 1989, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

MOTHER-TO-CHILD TRANSMISSION IN HTLV-I ASSOCIATED MYELOPATHY

R. Rosales, M. Osame, K. Usuku, 1987, The Lancet.

Characteristic expression of cell adhesion molecules in adhalin deficiency

K. Arimura, M. Nakagawa, M. Osame, 1996, Journal of the Neurological Sciences.

Familial spastic paraplegia with mental impairment and thin corpus callosum

A. Nakamura, M. Nakagawa, S. Izumo, 1995, Journal of the Neurological Sciences.

Choroideremia with leukoencephalopathy and arylsulfatase A pseudodeficiency

M. Nakagawa, M. Osame, S. Ijichi, 1996, Journal of the Neurological Sciences.

Increased expression of thrombomodulin on the cultured human umbilical vein endothelial cells and mouse hemangioma cells by cyclic AMP.

S. Yamamoto, T. Ito, I. Maruyama, 1991, Thrombosis research.

Unilateral toe-walking secondary to intramuscular hemangioma in the gastrocnemius

S. Kitajima, E. Matsuura, M. Osame, 2005, Neurology.

Effects of omega-3 polyunsaturated fatty acids on inflammatory markers in COPD.

K. Arimura, M. Osame, W. Matsuyama, 2005, Chest.

Determination of urine thiocyanate in patients with amyotrophic lateral sclerosis

M. Nakagawa, S. Izumo, M. Osame, 1984, Acta neurologica Scandinavica.

Morphogenesis of nuclear inclusions in the soleplate region of rat skeletal muscle fibers following chronic daily administration of neostigmine

M. Kawabuchi, M. Osame, T. Kanaseki, 1989, Cell and Tissue Research.

[Clinical investigation of 15 patients with pulmonary cryptococcosis--clinical comparison of HTLV-I carriers and non-carriers].

M. Osame, H. Fukunaga, W. Matsuyama, 1999, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

A prospective uncontrolled trial of fermented milk drink containing viable Lactobacillus casei strain Shirota in the treatment of HTLV-1 associated myelopathy/tropical spastic paraparesis

K. Arimura, S. Izumo, M. Osame, 2005, Journal of the Neurological Sciences.

Predictive value of serial platelet count and VEGF determination for the management of DIC in the Crow-Fukase (POEMS) syndrome.

I. Maruyama, K. Arimura, T. Hashiguchi, 2003, Internal medicine.

Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 are increased in POEMS syndrome

K. Arimura, E. Matsuura, T. Hashiguchi, 2001, Neurology.

Enhanced inhibition of lymphocyte activation byMycobacterium avium complex in human T lymphotrophic virus type I carriers

M. Osame, R. Kubota, W. Matsuyama, 2001, Thorax.

Two cases of idiopathic CD4+ T-lymphocytopenia in elderly patients.

M. Osame, W. Matsuyama, F. Iwami, 1998, Internal medicine.

Ocular manifestations in patients infected with human T-lymphotropic virus type I.

I. Maruyama, M. Matsumoto, N. Ohba, 1989, Japanese journal of ophthalmology.

Histopathological and ultrastructural features of feline hereditary cerebellar cortical atrophy: a novel animal model of human spinocerebellar degeneration

K. Arimura, Y. Isashiki, S. Izumo, 1998, Acta Neuropathologica.

Study of hereditary cerebellar degeneration in cats.

M. Mochizuki, S. Izumo, M. Osame, 1996, American journal of veterinary research.

Notice of retraction: Increased expression of TRAIL receptor 3 on eosinophils in Churg-Strauss syndrome (Arthritis Rheum 2007;56:662-73).

K. Arimura, T. Wada, M. Osame, 2008, Arthritis & Rheumatism.

Partial characterization of leucocyte alpha-glucosidase in late onset glycogenosis type II.

T. Kohriyama, M. Osame, R. Hiwatari, 1989, The Tohoku journal of experimental medicine.

[5 cases of dystonia with marked diurnal fluctuation and special reference to homovanillic acid in CSF].

M. Nomoto, M. Osame, A. Igata, 1984, Rinsho shinkeigaku = Clinical neurology.

Hermansky-Pudlak syndrome with a novel mutation.

K. Arimura, M. Osame, W. Matsuyama, 2005, Internal medicine.

Neurologic manifestations of Kanzaki disease

K. Arimura, Y. Kurono, M. Osame, 2004, Neurology.

Degradative activity of granzyme A on skeletal muscle proteins in vitro: A possible molecular mechanism for muscle fiber damage in polymyositis

Koichiro Nakamura, S. Ishiura, M. Osame, 1993, Neuromuscular Disorders.

Paucity and disorganization of presynaptic membrane active zones in the lambert‐eaton myasthenic syndrome

A. Engel, E. Lambert, M. Osame, 1982 .

Expression of the heparin-binding growth factor midkine in the cerebrospinal fluid of patients with neurological disorders.

M. Goto, F. Matsuda, T. Muramatsu, 2008, Internal medicine.

Midkine exists in astrocytes in the early stage of cerebral infarction.

M. Goto, T. Muramatsu, S. Izumo, 1998, Brain research. Developmental brain research.

The effects of shounousui on the three responses of the blink reflex in man

S. Suwazono, K. Arimura, M. Osame, 1997, Muscle & nerve.

Human T‐lymphotropic virus type I‐associated myelopathy/tropical spastic paraparesis and systemic lupus erythematosus

M. Osame, O. Takayanagui, T. Bíscaro, 1997, Neurology.

Clonal expansion within CD4+ and CD8+ T cell subsets in human T lymphotropic virus type I-infected individuals.

P. Gregersen, W. Hall, S. Yashiki, 1998, Journal of immunology.

Targeted Deletion of Both Thymidine Phosphorylase and Uridine Phosphorylase and Consequent Disorders in Mice

M. Fukushima, T. Noda, K. Miyazono, 2002, Molecular and Cellular Biology.

Different pattern of HSP47 expression in skeletal muscle of patients with neuromuscular diseases

K. Arimura, E. Matsuura, M. Osame, 2007, Neuromuscular Disorders.

Spread of HTLV-I Between Lymphocytes by Virus-Induced Polarization of the Cytoskeleton

Mitsuhiro Osame, Charles R. M. Bangham, Yuetsu Tanaka, 2003, Science.

Screening of SLC25A13 mutations in early and late onset patients with citrin deficiency and in the Japanese population: Identification of two novel mutations and establishment of multiple DNA diagnosis methods for nine mutations

T. Saheki, M. Nakagawa, Keiko Kobayashi, 2002, Human mutation.

Phenotypic variation in a large Japanese family with Miyoshi myopathy with nonsense mutation in exon 19 of dysferlin gene

M. Nakagawa, H. Takashima, K. Goto, 2001, Journal of the Neurological Sciences.

[A case of nemaline myopathy with ophthalmoplegia and mitochondrial abnormalities (author's transl)].

M. Osame, H. Fukunaga, Y. Arimura, 1978, Rinsho shinkeigaku = Clinical neurology.

HTLV-I proviral DNA amount correlates with infiltrating CD4+ lymphocytes in the spinal cord from patients with HTLV-I-associated myelopathy

T. Fujiyoshi, S. Yashiki, S. Sonoda, 1994, Journal of Neuroimmunology.

Accumulation of mitochondrial ATP synthase subunit c in muscle in a patient with neuronal ceroid lipofuscinosis (late infantile form)

J. Ezaki, E. Kominami, M. Osame, 1997, Acta Neuropathologica.

Significantly increased antibody response to heterogeneous nuclear ribonucleoproteins in cerebrospinal fluid of multiple sclerosis patients but not in patients with human T-lymphotropic virus type I—associated myelopathy/tropical spastic paraparesis

S. Izumo, M. Osame, Y. Yakushiji, 2011, Journal of NeuroVirology.

Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase.

A. Fukamizu, J. Ishida, S. Aratani, 2009, International journal of molecular medicine.

Detection of the soluble form of the Fas molecule in patients with multiple sclerosis and human T-lymphotropic virus type I-associated myelopathy

N. Yanagisawa, C. Koh, M. Osame, 1997, Journal of Neuroimmunology.

Fine mapping of 16q-linked autosomal dominant cerebellar ataxia type III in Japanese families

K. Arimura, M. Nakagawa, R. Hirano, 2004, Neurogenetics.

Autosomal dominant early onset dementia and leukoencephalopathy in a Japanese family: clinical, neuroimaging and genetic studies

K. Arimura, M. Nakagawa, M. Nagai, 1997, Journal of the Neurological Sciences.

Highly accumulated platelet vascular endothelial growth factor in coagulant thrombotic region

I. Maruyama, K. Arimura, T. Hashiguchi, 2003, Journal of thrombosis and haemostasis : JTH.

Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8(+) T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP).

S. Jacobson, M. Brennan, Y. Yamano, 2002, Blood.

The main HTLV-I-harboring cells in the muscles of viral carriers with polymyositis are not macrophages but CD4+ lymphocytes

K. Arimura, M. Nakagawa, R. Rosales, 1996, Acta Neuropathologica.

Detection of HTLV‐I provirus by in situ polymerase chain reaction in mononuclear inflammatory cells in skeletal muscle of viral carriers with polymyositis

K. Arimura, M. Nakagawa, S. Izumo, 1995, Muscle & nerve.

The Influence of HLA Class I Alleles and Heterozygosity on the Outcome of Human T Cell Lymphotropic Virus Type I Infection1

A. Lloyd, K. Welsh, K. Jeffery, 2000, The Journal of Immunology.

Involvement of enhanced sensitivity of N-methyl-d-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity

H. Nakanishi, K. Murao, S. Moriguchi, 2001, Brain Research.

Capillary changes in skeletal muscle of patients with Ullrich's disease with collagen VI deficiency

K. Arimura, M. Nakagawa, T. Hashiguchi, 2003, Acta Neuropathologica.

Cross-Sectional Analysis of Neurological Findings among Healthy Elderly: Study in a Remote Island in Kagoshima, Japan

S. Akiba, K. Arimura, M. Nakagawa, 2001, Neuroepidemiology.

MRI studies of spinal visceral larva migrans syndrome

K. Arimura, E. Matsuura, M. Osame, 2006, Journal of the Neurological Sciences.

Pulmonary dirofilariasis with serologic study on familial infection with Dirofilaria immitis.

M. Osame, Y. Nawa, Y. Hirotsu, 2004, Internal medicine.

CHANGES AT THE NEUROMUSCULAR JUNCTIONS IN THE AFFECTED MUSCLES OF NEOSTIGMINE-TREATED RATS, TENOTOMIZED RATS AND A PATIENT WITH NEMALINE MYOPATHY

M. Kawabuchi, M. Osame, H. Sugita, 1977 .

[A case of pulmonary infiltration with eosinophilia caused by Ascaris suum].

M. Osame, W. Matsuyama, F. Iwami, 1998, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

[Mitochondrial encephalomyopathy with multiple brain infarcts].

S. Matsuda, M. Osame, M. Kuriyama, 1985, Rinsho shinkeigaku = Clinical neurology.

Glycogen storage disease. Studies related to the mechanism of glycogenosome formation.

S. Fukuda, M. Osame, T. Hamada, 1983, Pathology, research and practice.

Human acid maltase‐deficient myogenic cell transformation with origin‐defective SV40: Characterization of a cloned line

M. Osame, M. Hattori, F. Usuki, 1991, Muscle & nerve.

[Case of hypertrophic meningitis with vasculitis syndrome].

I. Maruyama, M. Osame, K. Nakahara, 1994, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

Chronic progressive myelopathy associated with elevated antibodies to human T‐lymphotropic virus type I and adult T‐cell leukemialike cells

S. Izumo, M. Osame, K. Usuku, 1987, Annals of neurology.

A clinical study of adult human parvovirus B19 infection.

M. Osame, M. Tara, H. Hayakawa, 2002, Internal medicine.

[A case of congenital antithrombin III deficiency complicated by an internal carotid artery occlusion].

M. Osame, Y. Maruyama, K. Shinmyozu, 1986, Rinshō shinkeigaku Clinical neurology.

Abundant tax protein expression in CD4+ T cells infected with human T-cell lymphotropic virus type I (HTLV-I) is prevented by cytotoxic T lymphocytes.

J. Weber, Yuetsu Tanaka, Y. Tanaka, 2000, Blood.

HTLV-I-associated myelopathy (HAM): epidemiology, clinical features, and pathomechanism

I. Maruyama, K. Arimura, M. Nakagawa, 1992 .

Frameshift mutation in the collagen VI gene causes Ullrich's disease

K. Arimura, M. Nakagawa, T. Hashiguchi, 2001, Annals of neurology.

Cardiac involvement in mitochondrial diseases. A study on 17 patients with documented mitochondrial DNA defects.

M. Miyata, M. Nakagawa, M. Osame, 1995, Circulation.

Molecular mechanism of rigid spine with muscular dystrophy type 1 caused by novel mutations of selenoprotein N gene

K. Arimura, M. Nakagawa, R. Hirano, 2006, Neurogenetics.

Serum levels of vascular endothelial growth factor dependent on the stage progression of lung cancer.

K. Arimura, T. Hashiguchi, M. Osame, 2000, Chest.

A Study on the Antithrombotic Effect of Danazol

I. Maruyama, M. Osame, K. Shinmyozu, 1990 .

Cellular immune response to HTLV-1

Mitsuhiro Osame, M. Osame, Charles R. M. Bangham, 2005, Oncogene.

Degenerate specificity of HTLV-1-specific CD8+ T cells during viral replication in patients with HTLV-1-associated myelopathy (HAM/TSP).

S. Izumo, M. Osame, R. Kubota, 2003, Blood.

replication in patients with HTLV-I-associated myelopathy ( HAM / TSP ) Degenerate specificity of HTLV-I-specific CD 8 + T cells during viral

S. Izumo, M. Osame, R. Kubota, 2002 .

Detection of human T cell lymphotropic virus type I proviral DNA and its gene expression in synovial cells in chronic inflammatory arthropathy.

T. Nakajima, I. Maruyama, I. Kitajima, 1991, The Journal of clinical investigation.

Leber's hereditary optic neuropathy: mitochondrial and biochemical studies on muscle biopsies.

M. Nakagawa, N. Ohba, M. Osame, 1987, The British journal of ophthalmology.

Marked increase in plasma interleukin-6 in burn patients.

I. Maruyama, M. Osame, M. Ueyama, 1992, The Journal of laboratory and clinical medicine.

Human T cell leukemia virus type I-infected patients with Hashimoto's thyroiditis and Graves' disease.

N. Mori, M. Osame, M. Tomita, 2005, The Journal of clinical endocrinology and metabolism.

A new type of hereditary motor and sensory neuropathy linked to chromosome 3

K. Arimura, M. Nakagawa, S. Izumo, 1997, Annals of neurology.

SET binding factor 2 (SBF2) mutation causes CMT4B with juvenile onset glaucoma

M Nakagawa, J. Lupski, C. Boerkoel, 2004, Neurology.

Mucolipidosis III (pseudo-Hurler polydystrophy); clinical studies in aged patients in one family

M. Osame, S. Gasa, M. Kuriyama, 1997, Journal of the Neurological Sciences.

Genetic Stability of Human T Lymphotropic Virus Type I despite Antiviral Pressures by CTLs1

T. Gojobori, Kousuke Hanada, K. Arimura, 2007, The Journal of Immunology.

Hereditary motor and sensory neuropathy with myelin folding and juvenile onset glaucoma

M. Nakagawa, K. Unoki, H. Takashima, 2000, Neurology.

Morphological study on the hereditary neurogenic amyotrophic dogs: Accumulation of lipid compound-like structures in the lower motor neuron

S. Izumo, M. Osame, F. Ikuta, 2004, Acta Neuropathologica.

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population

M. R. Sargolzaee, K. Arimura, H. Najmabadi, 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Analysis of CCG repeats in Huntingtin gene among HD patients and normal populations in Japan.

M. Nakagawa, A. Karami, M. Osame, 2008, Archives of medical research.

Steroid-responsive myalgia in a patient with Becker muscular dystrophy

Koichiro Nakamura, M. Nakagawa, M. Osame, 1993, Journal of the Neurological Sciences.

Pathological characteristics of skeletal muscle in Ullrich's disease with collagen VI deficiency

K. Arimura, M. Nakagawa, M. Osame, 2003, Neuromuscular Disorders.

[Blood coagulation studies in a family with congenital plasminogen abnormality--with a special relevance to the association of thrombotic tendency with abnormal plasminogen].

M. Osame, Y. Maruyama, K. Shinmyozu, 1986, [Rinsho ketsueki] The Japanese journal of clinical hematology.

HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy.

M. Nowak, A. Lloyd, G. Ogg, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Nationwide survey of HTLV‐I–associated myelopathy in Japan: Association with blood transfusion

S. Nagataki, R. Janssen, R. Khabbaz, 1990, Annals of neurology.

ApaI polymorphism of vitamin D receptor gene is associated with susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis in HTLV-1 infected individuals

K. Arimura, S. Izumo, M. Osame, 2005, Journal of the Neurological Sciences.

Desert hedgehog-patched 2 expression in peripheral nerves during Wallerian degeneration and regeneration

R. Mirsky, K. Jessen, M. Osame, 2006 .

0331 Desert hedgehog-patched2 expression in peripheral nerves during wallerian degeneration and regeneration

R. Mirsky, K. Jessen, M. Osame, 2005, Journal of the Neurological Sciences.

A case of HTLV-I-associated myelopathy with IgA nephropathy and pseudohypoparathyroidism type 1.

M. Osame, Y. Yoshida, Y. Arimura, 1991, Japanese journal of medicine.

Necrotising vasculitis with conduction block in mononeuropathy multiplex with cold agglutinins

K. Arimura, M. Osame, F. Umehara, 1999, Journal of neurology, neurosurgery, and psychiatry.

[Medullary infarction due to vertebral dissecting aneurysm in a patient with Behçet's disease].

M. Osame, F. Umehara, Y. Maruyama, 1996, Rinshō shinkeigaku Clinical neurology.

Microvascular endothelial abnormality in skeletal muscle from a patient with gastric cancer without dermatomyositis

K. Arimura, M. Nakagawa, M. Osame, 2000, Acta Neuropathologica.

Genetic variability in the extracellular matrix protein as a determinant of risk for developing HTLV-I-associated neurological disease

K. Arimura, S. Izumo, C. Bangham, 2006, Immunogenetics.

Three cases of juvenile onset HTLV-I-associated myelopathy with pseudohypoparathyroidism

M. Nakagawa, M. Osame, K. Nakahara, 1993, Journal of the Neurological Sciences.

Cerebrotendinous xanthomatosis: cranial CT and MRI studies in eight patients

M. Nakagawa, M. Osame, M. Kuriyama, 2004, Neuroradiology.

Early clinical signs and imaging findings in Gerstmann–Sträussler–Scheinker syndrome (Pro102Leu)

K. Arimura, R. Hirano, H. Takashima, 2006, Neurology.

Expression of adhesion molecules and monocyte chemoattractant protein-1 (MCP-1) in the spinal cord lesions in HTLV-I-associated myelopathy

E. Sato, M. Takeya, Kiyoshi Takahashi, 1996, Acta Neuropathologica.

Levodopa in pregnancy.

M. Nomoto, S. Iwata, M. Osame, 1997, Movement disorders : official journal of the Movement Disorder Society.

Polymorphism in the interleukin-10 promoter affects both provirus load and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.

Mitsuhiro Osame, Kimiyoshi Arimura, Alun L Lloyd, 2004, The Journal of infectious diseases.

Patients with homocystinuria: high metal concentrations in hair, blood and urine

M. Osame, R. Hamada, H. Akagi, 1992, Acta neurologica Scandinavica.

Expression of thrombomodulin, caveolin‐3, and desmin on muscle fibers in neuromuscular diseases

M. Osame, I. Higuchi, I. Maruyama, 1999, Muscle & nerve.

Characteristic Expression of Thrombomodulin in the Muscle Sarcoplasm in Patients with the Acute Phase of Rhabdomyolysis

M. Osame, I. Higuchi, M. Inose, 2000, European Neurology.

Lymphocyte subsets in muscle biopsies of human T-lymphotropic virus type I carriers with polymyositis.

S. Izumo, M. Osame, I. Higuchi, 1992, Internal medicine.

An overexpression of fibroblast growth factor (FGF) and FGF receptor 4 in a severe clinical phenotype of facioscapulohumeral muscular dystrophy

K. Arimura, M. Osame, I. Higuchi, 2000, Muscle & nerve.

Abnormal expression of laminin suggests disturbance of sarcolemma-extracellular matrix interaction in Japanese patients with autosomal recessive muscular dystrophy deficient in adhalin.

K. Campbell, S. Roberds, M. Nakagawa, 1994, The Journal of clinical investigation.

Detection of DNA fragmentation of myonuclei in myotonic dystrophy by double staining with anti-emerin antibody and by nick end-labeling

M. Nakagawa, M. Osame, I. Higuchi, 2000, Journal of the Neurological Sciences.

Phenotypic Duchenne muscular dystrophy with C-terminal domain.

T. Moritoyo, M. Osame, I. Higuchi, 1992, Pediatric neurology.

Caveolin‐3 and sarcoglycans in the vacuolar myopathies and centronuclear myopathy

M. Osame, I. Higuchi, M. Inose, 1999, Muscle & nerve.

Cardiac involvement in congenital myopathy.

C. Tei, Y. Otsuji, S. Minagoe, 1985, International journal of cardiology.

Mechanomyographic determination of post-activation potentiation in myopathies

K. Arimura, M. Osame, I. Higuchi, 2006, Clinical Neurophysiology.

New missense mutation in the alpha-sarcoglycan gene in a Japanese patient with severe childhood autosomal recessive muscular dystrophy with incomplete alpha-sarcoglycan deficiency

K. Arimura, M. Nakagawa, M. Osame, 1997, Journal of the Neurological Sciences.

Allogenic bone marrow transplantation as a treatment for adult T-cell leukemia.

H. Taji, Y. Morishima, H. Sao, 1999, International journal of hematology.

Immunocytochemical Analysis of the Cellular Infiltrate in the Spinal Cord Lesions in HTLV‐I‐Associated Myelopathy

M. Nakagawa, S. Izumo, M. Osame, 1993, Journal of neuropathology and experimental neurology.

Alteration of cytokine levels by fosfomycin and prednisolone in spontaneous proliferation of cultured lymphocytes from patients with HTLV-I-associated myelopathy (HAM/TSP)

K. Arimura, Y. Yamano, M. Osame, 1997, Journal of the Neurological Sciences.

Detection of human T-lymphotropic virus type I p40tax protein in cerebrospinal fluid cells from patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.

Y. Tanaka, S. Izumo, M. Nagai, 1999, Journal of neurovirology.

Analysis Of Htlv-I Proviral Load In 202 Ham/Tsp Patients And 243 Asymptomatic Htlv-I Carriers: High Proviral Load Strongly Predisposes To Ham/Tsp

S. Izumo, M. Nagai, C. Bangham, 1998 .

Predictive value of the prolonged exercise test in hypokalemic paralytic attack

S. Suwazono, K. Arimura, M. Osame, 1995, Muscle & nerve.

Blood Dolichols in a Patient with Abetalipoproteinaemia

M. Osame, K. Nakahara, H. Nakagawa, 1999, Annals of clinical biochemistry.

[Crow-Fukase (POEMS) syndrome].

K. Arimura, T. Hashiguchi, M. Osame, 2000, Ryoikibetsu shokogun shirizu.

[Recent advance in neuroimmunology].

K. Arimura, M. Osame, 1998, Rinsho shinkeigaku = Clinical neurology.

Selective matrix metalloproteinase inhibitor, N-biphenyl sulfonyl phenylalanine hydroxamic acid, inhibits the migration of CD4+ T lymphocytes in patients with HTLV-I-associated myelopathy

M. Osame, F. Umehara, R. Maekawa, 2002, Journal of Neuroimmunology.

Neuropathology of HTLV-1-associated myelopathy (HAM/TSP).

E. Sato, S. Izumo, M. Osame, 1997, Leukemia.

Dominantly inherited motor and sensory neuropathy with excessive myelin folding complex

M. Nakagawa, H. Yoshikawa, S. Izumo, 2004, Acta Neuropathologica.

Deletion in chromosome 17p11.2 including the peripheral myelin protein-22 (PMP-22) gene in hereditary neuropathy with liability to pressure palsies

K. Arimura, M. Nakagawa, S. Izumo, 1995, Journal of the Neurological Sciences.

Cytotoxic T–cell abundance and virus load in human immunodeficiency virus type 1 and human T–cell leukaemia virus type 1

M. Nowak, D. Wodarz, G. Ogg, 2001, Proceedings of the Royal Society of London. Series B: Biological Sciences.

Usefulness of proviral load measurement for monitoring of disease activity in individual patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis

Y. Yamano, S. Izumo, M. Osame, 2003, Journal of NeuroVirology.

Histochemical and ultrastructural pathology of skeletal muscle in a patient with abetalipoproteinemia

M. Osame, I. Higuchi, M. Kuriyama, 2004, Acta Neuropathologica.

Chronic inflammatory demyelinating polyneuropathy: Histological and immunopathological studies on biopsied sural nerves

S. Izumo, M. Osame, F. Umehara, 1994, Journal of the Neurological Sciences.

Effects of LDL-apheresis on serum lipoprotein (a), C4b binding protein, protein C, protein S, and complement components.

M. Osame, M. Kuriyama, K. Shinmyozu, 1994, Journal of atherosclerosis and thrombosis.

Midkine (MK) expression in extraembryonic tissues, amniotic fluid, and cerebrospinal fluid during mouse embryogenesis.

T. Muramatsu, M. Osame, M. Ozawa, 1995, Journal of biochemistry.

Statistically significant differences in the number of CD24 positive muscle fibers and satellite cells between sarcoglycanopathy and age-matched Becker muscular dystrophy patients.

K. Arimura, M. Nakagawa, M. Osame, 1999, Internal medicine.

The agonist of the protease-activated receptor-1 (PAR1) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human vascular smooth muscle cells

M. Nakata, I. Maruyama, I. Kitajima, 2003, Cellular and Molecular Life Sciences CMLS.

Immunocytochemical Study on Endothelial Markers with the Cerebral Vessel from a Patient with Familial Moyamoya Disease

H. Ohtani, M. Osame, K. Shinmyozu, 1991, Thrombosis and Haemostasis.

Mitochondrial abnormalities in extraocular muscles in myotonic dystrophy

M. Nakagawa, N. Ohba, Y. Isashiki, 1989 .

A case of paternally inherited congenital myotonic dystrophy.

T. Miki, M. Nakagawa, T. Miki, 1994, Journal of medical genetics.

Characteristics of dynamic mutation in Japanese myotonic dystrophy

T. Ogihara, M. Nakagawa, T. Miki, 1994, Japanese Journal of Human Genetics.

Cerebrovascular disorders and genetic polymorphisms: mitochondrial DNA5178C is predominant in cerebrovascular disorders

S. Akiba, K. Arimura, M. Nakagawa, 2002, Journal of the Neurological Sciences.

Experimental germinaium dioxide-induced neuropathy in rats

S. Izumo, M. Osame, I. Higuchi, 2004, Acta Neuropathologica.

Posterior interosseous nerve syndrome with hourglass-like fascicular constriction of the nerve

K. Arimura, S. Yoshino, M. Osame, 2003, Journal of the Neurological Sciences.

Mitochondrial myopathy and familial thiamine deficiency

E. Naito, M. Osame, I. Higuchi, 2000, Muscle & nerve.

Pulmonary manifestations in cerebrotendinous xanthomatosis.

M. Osame, M. Kuriyama, M. Kawabata, 1998, Internal medicine.

Mitochondrial DNA mutation correlates with stage progression and prognosis in non‐small cell lung cancer

Mitsuhiro Osame, Masanori Nakagawa, M. Nakagawa, 2003, Human mutation.

Long-term follow-up study of health status in population living in methylmercury-polluted area.

T. Inaoka, T. Kitano, M. Nagano, 2005, Environmental sciences : an international journal of environmental physiology and toxicology.

Effects of Niceritrol on Lipoprotein (a), C 4b Binding Protein, Serum Amyloid P Protein, and Serum Amyloid A Protein in Cerebrovascular Diseases

M. Osame, M. Kuriyama, M. Maeda, 1993 .

Changes in serum lipoprotein(a) and C4b-binding protein levels after acute myocardial infarction.

M. Osame, M. Kuriyama, K. Miyahara, 1992, Japanese circulation journal.

Risk factors in normolipidemic male patients with coronary artery disease in Japanese.

M. Osame, M. Kuriyama, K. Miyahara, 1992, Japanese circulation journal.

[HTLV-I-associated myelopathy].

M. Osame, 1987, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

[HTLV-I-associated myelopathy].

M. Osame, 1999, Ryoikibetsu shokogun shirizu.

[n-Hexane polyneuropathy presenting with CIDP-like features].

K. Arimura, E. Matsuura, M. Osame, 2006, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

Changes in the Plasma Levels of Coagulation Regulatory Factors in Patients with Nephrotic Syndrome

I. Maruyama, M. Osame, T. Okadome, 1991 .

Markedly Reduced Plasma Free Protein S Levels in Patients with Hemophagocytic Histiocytosis

I. Maruyama, M. Osame, T. Itoyama, 1991 .

[Occurrence of subdural hematoma closely associated with danazol administration in a patient with refractory ITP].

I. Maruyama, M. Osame, Y. Maruyama, 1990, [Rinsho ketsueki] The Japanese journal of clinical hematology.

Clinical investigation of pulmonary Mycobacterium avium complex infection in human T lymphotrophic virus type I carriers.

M. Osame, H. Fukunaga, W. Matsuyama, 2000, Thorax.

[Pulmonary sclerosing hemangioma with specific CT findings].

M. Osame, W. Matsuyama, F. Iwami, 1998, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

Leber's hereditary optic neuropathy: mitochondrial andbiochemical studies onmuscle biopsies

M. Nakagawa, N. Ohba, M. Osame, 2011 .

Adult onset limb-girdle type mitochondrial myopathy with a mitochondrial DNA np8291 A-to-G substitution

M. Nakagawa, M. Osame, I. Higuchi, 1999, Journal of Human Genetics.

Treatment of cerebrotendinous xanthomatosis with low-density lipoprotein (LDL)-apheresis

Y. Tokimura, N. Tanaka, M. Osame, 1993, Journal of the Neurological Sciences.

[Cerebrotendinous xanthomatosis--a case of brain MRI abnormality and osteoporosis].

M. Nakagawa, M. Osame, M. Kuriyama, 1992, Rinsho shinkeigaku = Clinical neurology.

Osteoporosis and increased bone fractures in cerebrotendinous xanthomatosis.

M. Nakagawa, M. Osame, M. Kuriyama, 1993, Metabolism: clinical and experimental.

Electrophysiological studies in cerebrotendinous xanthomatosis.

K. Arimura, Y. Tokimura, M. Osame, 1992, Journal of neurology, neurosurgery, and psychiatry.

Atherogenic risk factors in cerebrotendinous xanthomatosis.

M. Osame, S. Arima, H. Tanaka, 1991, Clinica chimica acta; international journal of clinical chemistry.

(HAM-TSP) (HTLV-1)-infected T cells in HTLV-1-associated myelopathy Frequent clonal proliferation of human T-cell leukemia virus type 1

M. Yoshida, J. Fujisawa, S. Sonoda, 2011 .

Genetic control and dynamics of the cellular immune response to the human T-cell leukaemia virus, HTLV-I.

M. Nowak, D. Wodarz, K. Jeffery, 1999, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Type I-Infected Individuals VirusCell Subsets in Human T Lymphotropic T + and CD 8 + Clonal Expansion Within CD 4

P. Gregersen, W. Hall, S. Yashiki, 1998 .

Anti-viral and immunomodulatory effects of interferon-α on cultured lymphocytes from patients with human T lymphotropic virus type I-associated myelopathy (HAM/TSP)

W. Hall, S. Izumo, M. Nagai, 1995, Journal of Neuroimmunology.

VIRUSES DETECTED IN HTLV-I-ASSOCIATED MYELOPATHY AND ADULT T-CELL LEUKAEMIA ARE IDENTICAL ON DNA BLOTTING

M. Osame, Mitsuaki Yoshida, K. Usuku, 1987, The Lancet.

Cytokine Expression in the Spinal Cord Lesions in HTLV-l-associated Myelopathy

E. Sato, S. Izumo, M. Osame, 1994, Journal of neuropathology and experimental neurology.

Failure to detect HTLV type 1 DNA from HTLV type 1-seronegative patients with chronic progressive spastic paraparesis in Kagoshima.

S. Izumo, M. Nagai, M. Osame, 2002, AIDS research and human retroviruses.

Immunogenetic factors involved in the pathogenesis of adult T-cell leukemia and HTLV-I-associated myelopathy

T. Fujiyoshi, S. Yashiki, S. Sonoda, 1992 .

HTLV-I-associated myelopathy and adult T-cell leukemia cases in a family.

S. Sonoda, M. Osame, M. Kaji, 1989, European neurology.

Cytosolic Ca2+ increase and cell damage in L6 rat myoblasts by HMG-CoA reductase inhibitors.

T. Yada, M. Osame, K. Nakahara, 1994, Biochemical and biophysical research communications.

CD44 splice variant involvement in the chronic inflammatory disease of the spinal cord: HAM/TSP

S. Izumo, M. Osame, K. Usuku, 2000, Journal of Neuroimmunology.

Long‐term follow‐up of patients with Duchenne muscular dystrophy receiving ventilatory support

T. Moritoyo, M. Osame, H. Fukunaga, 1993, Muscle & nerve.

Electron microscopic abnormalities of skeletal muscle in patients with collagen VI deficiency in Ullrich's disease

I. Maruyama, K. Arimura, M. Nakagawa, 2002, Acta Neuropathologica.

[Two lung adenocarcinoma patients with multiple brain metastasis treated with Gefitinib and surviving more than 2 years].

K. Arimura, M. Osame, W. Matsuyama, 2006, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

[Frequency and clinical significance of congenital plasminogen abnormality in cerebral infarction].

M. Osame, Y. Maruyama, K. Shinmyozu, 1986, Rinsho shinkeigaku = Clinical neurology.

Morphologic findings in biopsied skeletal muscle and cultured fibroblasts from a female patient with Danon's disease (lysosomal glycogen storage disease without acid maltase deficiency)

M. Nakagawa, M. Osame, I. Higuchi, 1994, Journal of the Neurological Sciences.

Myopathy due to glycogen storage disease: pathological and biochemical studies in relation to glycogenosome formation.

I. Matsuda, S. Fukuda, M. Osame, 1983, Experimental and molecular pathology.

Evaluation of usefulness of anti-HTLV-I antibody titer measurement in the spinal fluid for establishing diagnosis of HAM/TSP

M. Nakagawa, M. Osame, K. Usuku, 1999 .

Pigmentary retinal degeneration in patients with HTLV-I-associated myelopathy.

N. Ohba, K. Nakao, Y. Isashiki, 1989, Japanese journal of ophthalmology.

[Adult-onset neuronal ceroid lipofuscinosis--a case report with biological study].

S. Izumo, M. Osame, M. Kuriyama, 1992, Rinsho shinkeigaku = Clinical neurology.

[Clinical aspects of mitochondrial encephalomyopathy--abnormality of mitochondrial respiratory chain].

M. Nakagawa, M. Osame, 1990, No to shinkei = Brain and nerve.

High CSF lactate and pyruvate content in Kearns‐Sayre syndrome

M. Osame, M. Kuriyama, Masahito Suehara, 1984, Neurology.

Paraneoplastic vasculitic neuropathy: immunohistochemical studies on a biopsied nerve and post‐mortem examination

I. Maruyama, E. Sato, S. Izumo, 1994, Journal of internal medicine.

[Symptomatic adrenoleukodystrophy heterozygote with fluctuated neurological symptoms--a case report].

M. Osame, M. Kuriyama, K. Matsumuro, 1991, Rinsho shinkeigaku = Clinical neurology.

Mononeuropathy associated with hyperthyroidism.

S. Izumo, M. Osame, S. Ijichi, 1990, Journal of neurology, neurosurgery, and psychiatry.

HTLV-I-associated myelopathy (HAM) treatment trials, retrospective survey and clinical and laboratory findings

S. Izumo, M. Osame, K. Usuku, 1989 .

Molecular pathological comparison of primary gastric B-celllymphomas in China and Japan: Polymerase chain reaction (PCR) analysis of immunoglobulin heavy chain gene variable region and direct sequencing of the product

M. Nakagawa, E. Sato, K. Hasui, 1999 .

Usefulness of transcutaneous Doppler jugular venous echo to predict pulmonary hypertension in COPD patients.

Y. Nakamura, M. Osame, W. Matsuyama, 2001, The European respiratory journal.

Freeze‐fracture electronmicroscopic analysis of plasma membranes of cultured muscle cells in Duchenne dystrophy

A. Engel, R. Scott, C. Rebouche, 1981, Neurology.

Reduced Foxp3 expression with increased cytomegalovirus-specific CTL in HTLV-I-associated myelopathy

Yuetsu Tanaka, K. Arimura, R. Hirano, 2008, Journal of Neuroimmunology.

Contralateral early blink reflex in patients with HTLV-I associated myelopathy/tropical spastic paraparesis

K. Arimura, M. Osame, Y. Arimura, 1995, Journal of the Neurological Sciences.

Diagnosis of dystrophinopathy by skin biopsy

M. Osame, I. Higuchi, T. Matsumura, 2002, Muscle & nerve.

Apolipoprotein E ε4

S. Sakoda, J. Sasaki, M. Osame, 1994, Neurology.

Leucocyte alpha-1,4- and alpha-1,6-glucosidase activities towards oligosaccharides in late onset glycogenosis type II.

M. Osame, R. Hiwatari, M. Kuriyama, 1990, The Tohoku journal of experimental medicine.

[Muscle type acid maltase deficiency. An intermediate case between childhood type and adult type (author's transl)].

M. Nakagawa, M. Osame, O. Nakazato, 1982, Rinshō shinkeigaku Clinical neurology.

Schwartz-Jampel syndrome associated with von Willebrand's disease

M. Osame, M. Kuriyama, K. Shinmyozu, 2004, Journal of Neurology.

Antibodies to potassium channels pc12 in serum of Isaacs' syndrome: Western blot and immunohistochemical studies

I. Kitajima, K. Arimura, M. Osame, 1997, Muscle & nerve.

Two cases of male hypogonadal osteoporosis

I. Kitajima, S. Izumo, S. Iwata, 1989, Journal of Bone and Mineral Metabolism.

"Association of apolipoprotein E allele !e4 with late-onset familial and sporadic Alzheimer's disease": Comment.

A. Matsunaga, J. Sasaki, S. Sakoda, 1994 .

The history of discovery and clinico-epidemiology of HTLV-I-associated myelopathy(HAM).

M. Osame, A. Igata, 1989, Japanese journal of medicine.

Detection of HTLV type I provirus by in situ polymerase chain reaction in mouthwash mononuclear cells of HAM/TSP patients and HTLV type I carriers.

A. Achiron, S. Izumo, M. Osame, 1997, AIDS research and human retroviruses.

Axonal damage revealed by accumulation of β-amyloid precursor protein in HTLV-I-associated myelopathy

S. Izumo, M. Osame, F. Umehara, 2000, Journal of the Neurological Sciences.

INFLAMMATORY CHANGES IN HAM/TSP OCCUR SIMULTANEOUSLY IN THE ENTIRE CNS: HISTOPATHOLOGIC ANALYSIS OF FOUR AUTOPSY CASES

S. Izumo, T. Moritoyo, M. Osame, 1999 .

First missense mutations (R388W and R425H) of AMPD1 accompanied with myopathy found in a Japanese patient

T. Morisaki, H. Morisaki, M. Osame, 2000, Human mutation.

Low Levels of Serum Apolipoprotein AI and AII in Senile Dementia

M. Osame, T. Yamano, Y. Hokezu, 1994, The Japanese journal of psychiatry and neurology.

Effects of thymectomy on late-onset myasthenia gravis without thymoma

K. Arimura, S. Kuwabara, T. Fukutake, 2007, Clinical Neurology and Neurosurgery.

Mechanism of action of voltage‐gated K+ channel antibodies in acquired neuromyotonia

K. Arimura, M. Kameyama, M. Osame, 2004, Annals of neurology.

Protective effect of MK-801 in methyl mercury induced neuronal injury

K. Murao, K. Arimura, K. Eto, 1998, Neuroscience Research.

[Clinical investigation of three cases of pulmonary eosinophilic granuloma].

M. Osame, W. Matsuyama, F. Iwami, 1997, Nihon Kyobu Shikkan Gakkai zasshi.

Differential effect of TGF-beta 1 on the in vitro activation of HTLV-I and the proliferative response of CD8+ T lymphocytes in patients with HTLV-I-associated myelopathy (HAM/TSP).

W. Hall, M. Nagai, M. Osame, 1995, Clinical immunology and immunopathology.

[HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)].

M. Osame, S. Ijichi, N. Ijichi, 1997, Nihon rinsho. Japanese journal of clinical medicine.

An autopsied case of the Crow-Fukase syndrome: a neuropathological study with emphasis on spinal roots

S. Izumo, M. Osame, F. Umehara, 1987, Acta Neuropathologica.

Fatigue and damage to the masseter muscle by prolonged low-frequency stimulation in the rat.

S. Harada, G. Ito, M. Osame, 2005, Archives of oral biology.

A multicenter case-control study of HTLV-I associated uveitis. Study Group for HTLV-I Associated Ocular Diseases.

K. Yamaguchi, N. Ohba, K. Nakao, 1994, Japanese journal of ophthalmology.

Parkinsonism in cerebrotendinous xanthomatosis.

M. Osame, M. Kuriyama, J. Fujiyama, 1991, Japanese journal of medicine.

Motor Nerve Terminal Calcium Channels in Lambert‐Eaton Myasthenic Syndrome

A. Engel, A. Vincent, C. Peers, 1989, Annals of the New York Academy of Sciences.

[A patient of ADEM with central and peripheral conduction block improved with ultra-high-dose methylprednisolone].

K. Arimura, M. Osame, A. Uehara, 2002, Rinsho shinkeigaku = Clinical neurology.

Hypercholestanolemia in Diagnosing Cerebrotendinous Xanthomatosis vs. Familial Hypercholesterolemia, Primary Biliary Cirrhosis, and Hypothyroidism

M. Osame, M. Kuriyama, J. Fujiyama, 1990 .

PS-19-10 Antibodies to potassium channel in Isaacs syndrome and other neurological disorders

Osamu Watanabe, Mitsuhiro Osame, Kimiyoshi Arimura, 1995 .

[HTLV-I-associated myelopathy].

M. Osame, 1999, Ryoikibetsu shokogun shirizu.

Sural nerve morphology in asymptomatic uremia.

R. Rosales, S. Izumo, M. Osame, 1988, European neurology.

Outbreak of Bronchiolitis obliterans Associated with Consumption of Sauropus androgynus in Japan – Alert of Food-Associated Pulmonary Disorders from Japan

K. Arimura, K. Imaizumi, T. Ogura, 2005, Respiration.

Neuropathology of human T lymphotropic virus type I‐associated myelopathy

S. Izumo, M. Osame, F. Umehara, 1997 .

Minifascicular neuropathy: a new concept of the human disease caused by desert hedgehog gene mutation.

G. Tate, M. Osame, F. Umehara, 2002, Cellular and molecular biology.

A hemophiliac with human immunodeficiency virus (HIV)-1-associated dementia complex.

K. Arimura, M. Osame, Y. Maruyama, 1995, Internal medicine.

Relapsing cervical cord lesions on MRI in patients with HTLV-I–associated myelopathy

M. Osame, F. Umehara, R. Okubo, 2006, Neurology.

Predominant recognition of human T cell leukemia virus type I (HTLV-I) pX gene products by human CD8+ cytotoxic T cells directed against HTLV-I-infected cells.

H. Inoko, M. Kannagi, S. Sato, 1991, International immunology.

Complete response to twice-a-day interferon-beta with standard interferon-alpha therapy in acute hepatitis C after a needle-stick.

M. Osame, M. Oketani, K. Shinmyozu, 1999, Journal of clinical gastroenterology.

[Respiratory failure and its care in Duchenne muscular dystrophy].

M. Osame, H. Fukunaga, Y. Sonoda, 1991, Rinsho shinkeigaku = Clinical neurology.

Epidemiology of progressive muscular dystrophy in Okinawa, Japan. Classification with molecular biological techniques.

M. Osame, K. Nakahara, I. Higuchi, 1991, Neuroepidemiology.

HISTOCHEMICAL ANALYSES IN THE SOLEUS MUSCLE OF RATS TREATED WITH NEOSTIGMINE

M. Kawabuchi, M. Osame, H. Fukunaga, 1979 .

EXPERIMENTAL MYOPATHY INDUCED BY NEOSTIGMINE METHYLSULPHATE

M. Kawabuchi, M. Osame, A. Igata, 1975, The Lancet.

Experimental Nemaline Rods Induced by Anticholinesterase Drug (Neostigmine Methylsulfate)

M. Kawabuchi, M. Osame, H. Sugita, 1975 .

HLA class I and class II of the Nivkhi, an indigenous population carrying HTLV-I in Sakhalin, Far Eastern Russia.

T. Imanishi, M. Yamashita, T. Fujiyoshi, 1998, Tissue antigens.

[A case of bronchiolitis obliterans syndrome successfully treated by Tiotropium bromide].

K. Arimura, M. Osame, W. Matsuyama, 2006, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

Accumulation of human T-lymphotropic virus type I (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy

K. Arimura, Tomonori Nakamura, S. Izumo, 2011, Journal of NeuroVirology.

Recent studies on the epidemiology, clinical features and pathogenic mechanisms of HTLV-I associated myelopathy (HAM/TSP) and other diseases associated to HTLV.

K. Arimura, M. Nakagawa, S. Izumo, 1997, Journal of neurovirology.

Familial skeletal myopathy with atrioventricular block.

M. Nakagawa, M. Osame, I. Higuchi, 1999, Internal medicine.

Human T-lymphotropic virus type I infections in western India.

S. Sonoda, M. Nomoto, M. Osame, 1993, AIDS.

An autoaggressive process against bystander tissues in HTLV-I-infected individuals: a possible pathomechanism of HAM/TSP.

I. Maruyama, S. Izumo, M. Nagai, 1993, Medical hypotheses.

Familial mitochondrial encephalomyopathy with deaf‐mutism, ophthalmoplegia and leukodvstrophy.

Y. Isashiki, M. Osame, I. Higuchi, 1995, Acta neurologica Scandinavica.

Behçet's disease and Sjögren syndrome in a patient with HTLV-I-associated myelopathy

M. Nakagawa, M. Osame, I. Higuchi, 1993, Journal of the Neurological Sciences.

Annulate lamellae‐soleplate nuclei associations in skeletal muscle fibers of rats during chronic high‐dose exposure to neostigmine

M. Kawabuchi, M. Osame, Y. Aika, 1989, The Anatomical record.

Lyme disease acquired outside of Japan.

M. Nakagawa, M. Osame, K. Matsumuro, 1992, Internal medicine.

Detection of human T cell lymphotropic virus type I proviral DNA and its gene expression in synovial cells in chronic inflammatory arthropathy.

I. Kitajima, K. Nishioka, M. Osame, 1991, The Journal of clinical investigation.

Serum levels of apoptosis-related molecules in patients with multiple sclerosis and human T-lymphotropic virus Type I-associated myelopathy.

C. Koh, M. Osame, A. Inoue, 1999, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Altered expression of atrial natriuretic peptide and contractile protein genes in hypertrophied ventricle of JVS mice with systemic carnitine deficiency.

T. Saheki, H. Itoh, M. Osame, 1997, Journal of molecular and cellular cardiology.

[A study on the frequency of von Willebrand factor deficiency state].

I. Maruyama, M. Osame, Y. Maruyama, 1991, [Rinsho ketsueki] The Japanese journal of clinical hematology.

Computed tomography in fetal methylmercury poisoning.

M. Osame, I. Mishima, A. Igata, 1993, Journal of toxicology. Clinical toxicology.

Mitochondrial encephalomyopathy with lactate-pyruvate elevation and brain infarctions.

M. Osame, J. Tateishi, A. Igata, 1984, Neurology.

Immunoadsorption therapy for myasthenia gravis.

M. Osame, N. Shibuya, T. Sato, 1994, Journal of neurology, neurosurgery, and psychiatry.

Vesnarinone inhibits production of HIV-1 in cultured cells.

T. Nakajima, I. Maruyama, I. Kitajima, 1993, Biochemical and biophysical research communications.

Pathogenesis and treatment of human T-cell lymphotropic virus Type I-associated myelopathy

M. Nagai, M. Osame, 2002, Expert review of neurotherapeutics.

Safety and efficacy of interferon-α in 167 patients with human T-cell lymphotropic virus type 1-associated myelopathy

Y. Itoyama, J. Kira, K. Arimura, 2007, Journal of NeuroVirology.

Human T-cell lymphotropic virus type-I (HTLV-I)-associated myelopathy/tropical spastic paraparesis with acute type of adult T-cell leukemia.

Yoshitaka, Tara, S. Izumo, 1995, Internal medicine.

Activation of discoidin domain receptor 1 on CD14-positive bronchoalveolar lavage fluid cells induces chemokine production in idiopathic pulmonary fibrosis (Journal of Immunology (2005) 174, (6490-6498))

K. Arimura, T. Yoshimura, M. Osame, 2008 .

Plasma Levels of Thrombin-antithrombin III Complex and β-thromboglobulin during the Presence of Anti-phospholipid Antibodies

I. Maruyama, M. Osame, K. Shinmyozu, 1991 .

The correlation between erythropoiesis and thrombopoiesis as an index for pre-operative autologous blood donation.

M. Osame, Y. Maruyama, K. Obama, 1999, Transfusion science.