B. Nepom

发表

A specific HLA-DP beta allele is associated with pauciarticular juvenile rheumatoid arthritis but not adult rheumatoid arthritis.

H A Erlich, W. Klitz, A. Begovich, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Critical contribution of beta chain residue 57 in peptide binding ability of both HLA-DR and -DQ molecules.

G. Nepom, W. Kwok, B. Nepom, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).

J. Shabanowitz, D. Hunt, V. Engelhard, 2001, Proceedings of the National Academy of Sciences of the United States of America.

HLA-DQ molecules form alpha-beta heterodimers of mixed allotype.

G. Nepom, W. Kwok, B. Nepom, 1988, Journal of immunology.

Transcomplementation of HLA Genes in IDDM: HLA-DQ α and β-Chains Produce Hybrid Molecules in DR3/4 Heterozygotes

G. Nepom, B. Nepom, D. Schwarz, 1987, Diabetes.

Specific genomic markers for the HLA-DQ subregion discriminate between DR4+ insulin-dependent diabetes mellitus and DR4+ seropositive juvenile rheumatoid arthritis

S. Holbeck, J. Hansen, G. Nepom, 1986, The Journal of experimental medicine.

Electrophoretic analysis of human HLA-DR antigens from HLA-DR4 homozygous cell lines: correlation between beta-chain diversity and HLA-D.

J. Hansen, G. Nepom, B. Nepom, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Immunogenetic similarities between patients with Felty's syndrome and those with clonal expansions of large granular lymphocytes in rheumatoid arthritis.

P. Davis, G. Starkebaum, T. Loughran, 1997, Arthritis and rheumatism.

The HLA-DR4 family of haplotypes consists of series of distinct DR and DS molecules

J. Silver, J. Hansen, S. Goyert, 1984, The Journal of experimental medicine.

Polyglot and polymorphism. An HLA update.

G. Nepom, B. Nepom, 1995, Arthritis and rheumatism.

Functional polymorphisms among HLA-DR4+ DR beta chains associated with limited peptide diversity.

P. Gregersen, G. Nepom, B. Nepom, 1987, Molecular immunology.

Brief Definitive Report Specific Genomic Markers for the Hla-dq Subregion Discriminate between Dr4 + Insulin- Dependent Diabetes Mellitus and Dr4 + Seropositive Juvenile Rheumatoid Arthritis

S. Holbeck, J. Hansen, G. Nepom, 2003 .

HLA-DQ alpha polymorphisms: oligonucleotide probes characterize the contribution of first and second domains to electrophoretic variants.

J. Johnston, S. Radka, B. Nepom, 1989, Human immunology.

HLA susceptibility genes in rheumatoid factor positive juvenile rheumatoid arthritis.

A. Begovich, B. Nepom, R. Vehe, 1990, The Journal of rheumatology. Supplement.

Juvenile rheumatoid arthritis and HLA: report of the Park City III workshop.

D. Glass, B. Nepom, 1992, The Journal of rheumatology. Supplement.

Electrophoretic variation between class II molecules expressed on HLA-DRw8 homozygous typing cells reveals multiple distinct haplotypes

J. Hansen, G. Baldwin, G. Nepom, 2004, Immunogenetics.

Erosive rheumatoid factor negative and positive rheumatoid arthritis are immunogenetically similar.

A. Begovich, D. Stage, G. Nepom, 1994, The Journal of rheumatology.

Psychosomatic musculoskeletal pain in childhood: clinical and psychological analyses of 100 children.

B. Nepom, E. Mellins, D. Sherry, 1991, Pediatrics.

Prognostic implications of HLA genotyping in the early assessment of patients with rheumatoid arthritis.

V. Gersuk, G. Nepom, B. Nepom, 1996, The Journal of rheumatology. Supplement.

Deficient antigen-presenting cell function in multiple genetic complementation groups of type II bare lymphocyte syndrome.

G. Nepom, W. Kwok, J. Blum, 1995, Journal of Clinical Investigation.

A deletion mutant defines DQβ variants within DR4 positive DQw3 positive haplotypes

G. Nepom, B. Nepom, Se Jong Kim, 1986 .

Modulation of HLA-DQ binding properties by differences in class II dimer stability and pH-dependent peptide interactions.

G. Nepom, W. Kwok, J. Buckner, 1996, Journal of immunology.

HLA-DR antigens on lymphoid cells differ from those on myeloid cells

J. Hansen, G. Nepom, B. Nepom, 1983, Nature.

Multiple Ia-like molecules characterize HLA-DR2-associated haplotypes which differ in HLA-D.

M. Wilson, J. Hansen, G. Nepom, 1984, Human immunology.

The molecular basis for HLA class II associations with rheumatoid arthritis

J. Hansen, G. Nepom, B. Nepom, 2004, Journal of Clinical Immunology.

The role of the major histocompatibility complex in autoimmunity.

B. Nepom, 1993, Clinical immunology and immunopathology.

Biochemical Analysis of DQ α Polymorphisms Defined by a Monoclonal Antibody

J. Johnston, S. Radka, B. Nepom, 1989 .

HLA genes associated with rheumatoid arthritis. Identification of susceptibility alleles using specific oligonucleotide probes.

D. Stage, L. A. Healey, G. Nepom, 1989, Arthritis and rheumatism.

A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles.

J. R. Rowe, H. Erlich, S. Scharf, 1989, The Journal of clinical investigation.

Transcomplementation of HLA genes in IDDM. HLA-DQ alpha- and beta-chains produce hybrid molecules in DR3/4 heterozygotes.

G. Nepom, B. Nepom, D. Schwarz, 1987, Diabetes.

HLA and T cell receptor polymorphisms in pauciarticular-onset juvenile rheumatoid arthritis.

U. Malhotra, B. Nepom, J. Nettles, 1991, Arthritis and rheumatism.

Specific HLA-DR4-associated histocompatibility molecules characterize patients with seropositive juvenile rheumatoid arthritis.

J. Hansen, G. Nepom, B. Nepom, 1984, The Journal of clinical investigation.

Epstein-Barr virus uses HLA class II as a cofactor for infection of B lymphocytes

Qingxue Li, L. Hutt-Fletcher, M. Spriggs, 1997, Journal of virology.

IDENTIFICATION OF HLA-Dw14 GENES IN DR4+ RHEUMATOID ARTHRITIS

S. Holbeck, G. Nepom, B. Nepom, 1986, The Lancet.

The HLA-DR4 family of haplotypes consists of series of distinct DR and DS molecules

J. Silver, J. Hansen, S. Goyert, 1984, The Journal of experimental medicine.

Association of HLA-Dw16 with rheumatoid arthritis in Yakima Indians. Further evidence for the "shared epitope" hypothesis.

G. Nepom, B. Nepom, J. Nettles, 1991, Arthritis and rheumatism.

The immunogenetics of juvenile rheumatoid arthritis.

B. Nepom, B Nepom, 1991, Rheumatic diseases clinics of North America.

DQw3 (DQw7, DQw8, DQw9): 2-D Gel Patterns

D. Monos, R. Winchester, R. Fauchet, 1989 .

Characterization of specific HLA-DQ alpha allospecificities by genomic, biochemical, and serologic analysis.

S. Holbeck, G. Nepom, S. Radka, 1987, Journal of immunology.

Biochemical definition of distinct HLA haplotypes associated with juvenile rheumatoid arthritis

J. Hansen, G. Nepom, B. Nepom, 1985 .

HLA and T cell receptor beta-chain DNA polymorphisms identify a distinct subset of patients with pauciarticular-onset juvenile rheumatoid arthritis.

P. Charmley, B. Nepom, P. Concannon, 1994, Arthritis and rheumatism.

Prediction of susceptibility to rheumatoid arthritis by human leukocyte antigen genotyping.

G. Nepom, B. Nepom, 1992, Rheumatic diseases clinics of North America.

HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments

V. Gersuk, J. O'dell, C. Haire, 1998, Annals of the rheumatic diseases.

Allelic polymorphism in transcriptional regulatory regions of HLA-DQB genes

G. Nepom, B. Nepom, J. Nettles, 1991, The Journal of experimental medicine.

HLA-DR4-Associated Disease: Oligonucleotide Probes Identify Specific Class II Susceptibility Genes in Type I Diabetes and Rheumatoid Arthritis

S. Holbeck, G. Nepom, J. Palmer, 1989 .

HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments

V. Gersuk, J. O'dell, C. Haire, 1998, Annals of the rheumatic diseases.

Deficient antigen-presenting cell function in multiple genetic complementation groups of type II bare lymphocyte syndrome.

B. Nepom, G. T. Nepom, Janice S. Blum, 1995, Journal of Clinical Investigation.