N. Staines

发表

Workshop report on some new ideas about the treatment of systemic lupus erythematosus

D. Isenberg, J. Berden, M. Linnik, 2002, Lupus.

Natural antibodies that react with V‐region peptide epitopes of DNA‐binding antibodies are made by mice with systemic lupus erythematosus as disease develops

W. Harris, C. Cunningham, N. Staines, 1997, Immunology.

Molecular Mechanisms of Immunological Self Recognition

N. Staines, 1994 .

Control of rheumatoid arthritis by oral tolerance.

G. Kingsley, G. Panayi, E. Choy, 2001, Arthritis and rheumatism.

Autologous Mixed Lymphocyte Responses in Experimentally-induced Arthritis of the Lewis Rat

N. Staines, A. Hamblin, B. Catchpole, 2002, Autoimmunity.

The human autoantigen MCP1 is required during early stages of DNA replication

C. Sunkel, M. Carmo-Fonseca, A. Nóvoa, 2004, Chromosome Research.

A deficiency of CD4+ CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen

N. Staines, H. Y. Wu, HY Wu, 2004, Lupus.

DNA antibody idiotypes. An analysis of their role in health and disease.

D. Isenberg, N. Staines, 1990, Journal of autoimmunity.

Diversity and Multispecificity of Autoantibodies Reactive with DNA: Some Evolutionary Implications

N. Staines, A. Morgan, H. Thompson, 1985 .

Autoreactivity in collagen-induced arthritis of rats: a potential role for T cell responses to self MHC peptides.

N. Staines, A. Hamblin, B. Catchpole, 2002, Journal of autoimmunity.

A role for DNA in anti-DNA antibodies binding to endothelial cells.

N. Staines, G. Frampton, J. Cameron, 1991, Journal of autoimmunity.

T cell lines generated with type II collagen proliferate in an autologous mixed lymphocyte response.

N. Staines, A. Hamblin, B. Catchpole, 2001, Journal of autoimmunity.

Antibodies: their structure and function

N. Staines, 1986 .

Importance of dose of type II collagen in suppression of collagen-induced arthritis by nasal tolerance.

D. Davies, N. Staines, J. Murphy, 2001, Arthritis and rheumatism.

Tolerogenic activity of polymerized type II collagen in preventing collagen-induced arthritis in rats.

B. Henderson, S. Hobbs, N. Staines, 1988, Clinical and experimental immunology.

Mucosal tolerance and suppression of collagen‐induced arthritis (CIA) induced by nasal inhalation of synthetic peptide 184‐198 of bovine type II collagen (CII) expressing a dominant T cell epitope

R. Holmdahl, V. Malmström, N. Staines, 1996, Clinical and experimental immunology.

Shared idiotypes are expressed on mouse and human anti-DNA autoantibodies.

D. Isenberg, Y. Naparstek, J. Rauch, 1985, Immunology.

Detection of human and murine common idiotypes of DNA antibodies in tissues and sera of patients with autoimmune diseases

D. Isenberg, N. Staines, C. Ravirajan, 1991, Clinical and experimental immunology.

Experimental studies on the response of the fish (Notothenia coriiceps Richardson, 1844) to parasite (Pseudoterranova decipiens Krabbe, 1878) and other irritant stimuli at Antarctic temperatures

N. Staines, F. Hernandez-Blazquez, O. Parra, 1999, Polar Biology.

The detection of Ia antibodies in polyspecific H-2 alloantisera absorbed with erythrocytes.

N. Staines, D. Davies, L. Ashton, 2008, Tissue antigens.

A Cardinal Role for I‐Region Antigens (Ia) in Immunological Enhancement, and the Clinical Implications

N. Staines, D. Davies, N. Staines, 1976, Transplantation reviews.

The dominant role of la antibodies in the passive enhancement of H‐2 incompatible skin grafts

K. Guy, N. Staines, D. Davies, 1975, European journal of immunology.

PASSIVE ENHANCEMENT OF H‐2 INCOMPATIBLE SKIN ALLOGRAFTS AND MLR INHIBITION BY CROSS‐REACTIVE Ia ANTIBODIES

K. Guy, N. Staines, N. Staines, 1975 .

THE EXPRESSION OF H‐2K, H‐2D AND Ia ANTIGENS IN VARIOUS TISSUES AS ASSESSED IN Fc RECEPTOR INHIBITION SYSTEMS

P. Halloran, C. David, V. Schirrmacher, 1975 .

Methods of Immunological Analysis

N. Staines, W. Albert, R. Masseyeff, 1993 .

Specificity and binding kinetics of murine lupus anti‐DNA monoclonal antibodies implicate different stimuli for their production

B. Sutton, N. Staines, E. Eivazova, 2000, Immunology.

Suppression of collagen induced arthritis by oral administration of type II collagen: changes in immune and arthritic responses mediated by active peripheral suppression.

N. Staines, N. Staines, H. Thompson, 1993, Autoimmunity.

Gastric administration of type II collagen delays the onset and severity of collagen-induced arthritis in rats.

N. Staines, H. Thompson, 1986, Clinical and experimental immunology.

DNA-binding antibodies and parasitic diseases.

N. Staines, A. Wozencraft, 1990, Parasitology today.

Different mechanisms by which anti‐DNA MoAbs bind to human endothelial cells and glomerular mesangial cells

T. Chan, N. Staines, G. Frampton, 1992, Clinical and experimental immunology.

Constraints on the Efficacy of Mucosal Tolerance in Treatment of Human and Animal Arthritic Diseases

John J Murphy, L. Marinova-Mutafchieva, N. Staines, 2004, Annals of the New York Academy of Sciences.

Prevention of pristane-induced arthritis by the oral administration of type II collagen.

M. Day, N. Staines, C. Elson, 1993, Immunology.

Identification of candidate endothelial cell autoantigens in systemic lupus erythematosus using a molecular cloning strategy: a role for ribosomal P protein P0 as an endothelial cell autoantigen.

D. Isenberg, J. Pearson, A. Panayiotou, 2000, Rheumatology.

Can we Predict the Biological Behaviour of Carcinoma of the Breast Using Monoclonal Antibodies and Auto-Antibodies?

H. Baum, N. Staines, A. Morgan, 1984 .

Could specific oral tolerance be a therapy for autoimmune disease?

N. Staines, H. Thompson, 1990, Immunology today (Amsterdam. Regular ed.).

Cells and tissues

N. Staines, W. Albert, R. Masseyeff, 1993 .

Contribution of the spleen, lymph nodes and bone marrow to the antibody response in collagen‐induced arthritis in the rat

N. Staines, N. Staines, J. Rahman, 1991, Clinical and Experimental Immunology.

Role of DNA-binding antibodies in kidney pathology associated with murine malaria infections

N. Staines, C. Lloyd, A. Wozencraft, 1990, Infection and immunity.

Collagen-induced arthritis in the rat: modification of immune and arthritic responses by free collagen and immune anti-collagen antiserum.

T. Hardingham, B. Henderson, N. Staines, 1981, Immunology.

Five groups of antigenic determinants on DNA identified by monoclonal antibodies from (NZB X NZW)F1 and MRL/Mp-lpr/lpr mice.

A. Lew, I. Olsen, N. Staines, 1985, Immunology.

Separation of two molecular species of the Sm antigen by affinity chromatography with murine monoclonal and human anti-nuclear autoantibodies.

P. Venables, R. Maini, P. Smith, 1983, Clinical and experimental immunology.

Phagocytosis and giant cell formation at 0° C by macrophage (MØ) of Notothenia coriiceps

N. Staines, F. Hernandez-Blazquez, J. Borges, 2002 .

A monoclonal antibody based solid-phase enzyme-binding assay to measure levels of placental alkaline phosphatase in serum of women during pregnancy.

N. Staines, A. Morgan, S. Contractor, 1985, Journal of immunological methods.

The Human Endoplasmic Reticulum Molecular Chaperone BiP Is an Autoantigen for Rheumatoid Arthritis and Prevents the Induction of Experimental Arthritis1

W. van Eden, D. Pappin, J. Lanchbury, 2001, The Journal of Immunology.

Induction of Experimental Arthritis for Rheumatoid Arthritis and Prevents the Molecular Chaperone BiP Is an Autoantigen The Human Endoplasmic Reticulum and

D. Pappin, J. Lanchbury, G. Panayi, 2001 .

Low affinity antibodies against collagen type II are associated with pathology in collagen-induced arthritis in mice.

M. Devey, S. Hobbs, N. Staines, 1990, Journal of autoimmunity.

Whither monoclonal antibodies?

A. Lew, N. Staines, 1980, Immunology.

Fine specificity of autoantibodies to calreticulin: epitope mapping and characterization

M. Michalak, M. Khamashta, K. Reid, 2000, Clinical and experimental immunology.

The influence of "I" region antibodies on transplants.

N. Staines, D. Davies, 1976, Advances in experimental medicine and biology.

Xenoantisera against lymphoid cells: specificity and use in monitoring purification of mouse and human histocompatibility antigens.

K. Guy, N. Staines, G. J. O'neill, 2008, Tissue antigens.

Suppression of collagen type II-induced arthritis by transfer of lymphoid cells from rats immunized with collagen.

B. Henderson, N. Staines, S. Knight, 1985, Clinical and experimental immunology.

Anti-DNA antibody synthesis after bone marrow transplantation: implications for IgG subclass restrictivity and pathogenicity of autoantibodies.

D. Isenberg, G. Gahrton, L. Hammarström, 1988, Bone marrow transplantation.

13 Autoantibodies Against DNA

N. Staines, 1994 .

Autoantibodies Against DNA

N. Staines, 1994 .

Probing molecular changes induced in DNA by reactive oxygen species with monoclonal antibodies.

H. Griffiths, J. Lunec, N. Staines, 1992, Immunology letters.

Histone Peptide-Induced Nasal Tolerance: Suppression of Murine Lupus1

N. Staines, F. Ward, H. Wu, 2002, The Journal of Immunology.

A monoclonal DNA-binding autoantibody causes a deterioration in renal function in MRL mice with lupus disease.

R. Lake, N. Staines, 1988, Clinical and Experimental Immunology.

Collagen arthritis--what can it teach us?

P. Wooley, N. Staines, N A Staines, 1994, British journal of rheumatology.

Idiotypes of DNA-Binding Autoantibodies:Mapping by Epitope Scanning and Molecular Modelling

D. Isenberg, B. Sutton, N. Staines, 1994 .

Molecular characterization of the bacteria adherent to human colorectal mucosa

J. Sanderson, D. Rampton, B. Hudspith, 2006, Journal of applied microbiology.

Molecular modeling of an anti-DNA autoantibody (V-88) and mapping of its V region epitopes recognized by heterologous and autoimmune antibodies.

B. Sutton, N. Staines, D. Williams, 1998, Journal of immunology.

Autoimmune Antibodies Region Epitopes Recognized by Heterologous Autoantibody ( V-88 ) and Mapping of Its V Molecular Modeling of an Anti-DNA

B. Sutton, N. Staines, David G. Williams, 1998 .

The Molecular Basis of Autoantibody Pathogenicity

D. Isenberg, N. Staines, 1994, Journal of the Royal Society of Medicine.

Primary sequence and location of the idiotopes of V-88, a DNA-binding monoclonal autoantibody, determined by idiotope scanning with synthetic peptides on pins.

D. Isenberg, O. Hartley, N. Staines, 1993, Immunology.

Involvement in lupus disease of idiotypes Id.F-423 and Id.IV-228 defined, respectively, upon foetal and adult MRL/Mp-lpr/lpr DNA-binding monoclonal autoantibodies.

N. Staines, C. Ravirajan, 1991, Immunology.

A human fetal monoclonal DNA-binding antibody shares idiotypes with fetal and adult murine monoclonal DNA-binding antibodies.

D. Isenberg, N. Staines, C. Ravirajan, 1990, Immunology.

The genetic control of antibody affinity. Evidence from breeding studies with mice selectively bred for either high or low affinity antibody production.

M. Steward, N. Staines, M. Reinhardt, 1979, Immunology.

Arthritis: Animal Models of Oral Tolerance a

N. Staines, F. Ward, H. Thompson, 1996, Annals of the New York Academy of Sciences.

Glomerulonephritis induced by pre-formed immune complexes containing monoclonal antibodies of defined affinity and isotype.

A. Lew, M. Steward, N. Staines, 1984, Clinical and experimental immunology.

A key role for fibronectin in the sequential binding of native dsDNA and monoclonal anti-DNA antibodies to components of the extracellular matrix: its possible significance in glomerulonephritis.

B. Henderson, R. Lake, N. Staines, 1985, Immunology.

DNA-binding antibodies derived from autoimmune MRL mice fail to induce clinical changes when administered to healthy animals

R. Lake, N. Staines, 1986, Agents and Actions.

The anti-arthritic and immunosuppressive effects of cyclosporine on arthritis induced in the rat by type II collagen.

B. Henderson, J. Cox, N. Staines, 1984, Clinical and experimental immunology.

Low‐affinity antibodies against collagen type II produced by lymph node cells are associated with pathology in collagen‐induced arthritis in rats

N. Staines, J. Rahman, J. Loh, 1992, Clinical and experimental immunology.

Expression and relationships of seven public idiotypes of DNA-binding autoantibodies on monoclonal antibodies and serum immunoglobulins.

D. Isenberg, R. Lake, N. Staines, 1993, Lupus.

Passive enhancement of mouse skin allografts. Specificity of the antiserum for major histocompatibility.

K. Guy, N. Staines, D. Davies, 1974, Transplantation.

Comparison of DNA antibody idiotypes in human sera: an international collaborative study of 19 idiotypes from 11 different laboratories.

A. Todd-Pokropek, D. Isenberg, J. Axford, 1990, Journal of autoimmunity.

MHC-derived peptides and the CD4+ T-cell repertoire: implications for autoimmune disease.

H. Baum, N. Staines, 1997, Cytokines, cellular & molecular therapy.

Haemolytic disease in mice induced by transplantation of hybridoma cells secreting monoclonal anti-erythrocyte autoantibodies.

L. A. Cooke, N. Staines, A. Morgan, 1982, Immunology.