Johannes van den Boom

发表

Transient domain interactions enhance the affinity of the mitotic regulator Pin1 toward phosphorylated peptide ligands.

D. Hoffmann, J. Dybowski, C. Wilms, 2013, Structure.

Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1

F. Trusch, Johannes van den Boom, P. Bayer, 2016, PloS one.

Ubiquitin-directed AAA+ ATPase p97/VCP unfolds stable proteins crosslinked to DNA for proteolysis by SPRTN

H. Meyer, Matthias Kracht, Johannes van den Boom, 2022, The Journal of biological chemistry.

The chaperone Lhs1 contributes to the virulence of the fish-pathogenic oomycete Aphanomyces invadans.

N. Sood, P. van West, F. Trusch, 2020, Fungal biology.

Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1

E. Rosta, S. Knauer, W. Arlt, 2018, The Journal of Biological Chemistry.

Structural basis of ubiquitin‐independent PP1 complex disassembly by p97

H. Saibil, H. Meyer, Johannes van den Boom, 2022, bioRxiv.

Structural Model of the Bilitranslocase Transmembrane Domain Supported by NMR and FRET Data

A. Sali, S. Jurga, M. Bonomi, 2015, PloS one.

JUNO Physics Prospects

Zheng Wang, W. He, Y. Liu, 2021, Proceedings of 37th International Cosmic Ray Conference — PoS(ICRC2021).

Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase

H. Meyer, Johannes van den Boom, P. Bayer, 2019, Biomolecules.

Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly

A. Musacchio, M. Kaiser, H. Meyer, 2021, Nature Structural & Molecular Biology.

Peptidyl Succinimidyl Peptides as Taspase 1 Inhibitors

M. Kaiser, S. Knauer, Johannes van den Boom, 2014, Chembiochem : a European journal of chemical biology.

Targeting of client proteins to the VCP/p97/Cdc48 unfolding machine

H. Meyer, Johannes van den Boom, Hemmo Meyer, 2023, Frontiers in Molecular Biosciences.

A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases.

M. Kaiser, H. Meyer, Johannes van den Boom, 2018, Angewandte Chemie.

VCP/p97-Mediated Unfolding as a Principle in Protein Homeostasis and Signaling.

H. Meyer, Johannes van den Boom, Hemmo Meyer, 2017, Molecular cell.

VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.

M. Kaiser, G. Iliakis, H. Meyer, 2016, Molecular cell.

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

M. Bollen, A. Musacchio, M. Kaiser, 2018, Molecular cell.

3′-Phosphoadenosine 5′-Phosphosulfate (PAPS) Synthases, Naturally Fragile Enzymes Specifically Stabilized by Nucleotide Binding*

Dominik Heider, Annalisa Pastore, A. Pastore, 2012, The Journal of Biological Chemistry.

A heterodimer of human 3'-phospho-adenosine-5'-phosphosulphate (PAPS) synthases is a new sulphate activating complex.

A. Matena, Johannes van den Boom, Nina M. Link, 2010, Biochemical and biophysical research communications.

Sonic hedgehog shedding results in functional activation of the solubilized protein.

H. Schöler, D. Hoffmann, P. Farshi, 2011, Developmental cell.

Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal Subgroups

D. Hoffmann, D. Heider, Johannes van den Boom, 2011, Evolutionary bioinformatics online.

The other side of the corona: nanoparticles inhibit the protease taspase1 in a size-dependent manner.

R. Stauber, S. Knauer, D. Docter, 2020, Nanoscale.

Protein phosphatase-1 complex disassembly by p97 is initiated through multivalent recognition of catalytic and regulatory subunits by the p97 SEP-domain adapters.

M. Kaiser, H. Meyer, Matthias Kracht, 2020, Journal of molecular biology.

VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

N. Mailand, G. Montoya, Saskia Hoffmann, 2023, bioRxiv.

The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase

M. Kaiser, H. Meyer, Matthias Kracht, 2023, Nature communications.

Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase

H. Meyer, Johannes van den Boom, P. Bayer, 2019, Biomolecules.

Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH.

E. Maspero, Johannes van den Boom, Nina Schulze, 2024, Molecular cell.

VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

Saskia Hoffmann, A. Mund, Julien P Duxin, 2024, Nature communications.

A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases.

M. Kaiser, Johannes van den Boom, F. Kaschani, 2018, Angewandte Chemie.

VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.

M. Kaiser, G. Iliakis, H. Funabiki, 2016, Molecular cell.

3′-Phosphoadenosine 5′-Phosphosulfate (PAPS) Synthases, Naturally Fragile Enzymes Specifically Stabilized by Nucleotide Binding

A. Pastore, D. Heider, Johannes van den Boom, 2012, The Journal of Biological Chemistry.