V. Cecchetti

发表

Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor.

Barbara Gatto, Jan Paeshuyse, Giuseppe Manfroni, 2009, Journal of medicinal chemistry.

Effects of KATPopeners on the QT prolongation induced by HERG-blocking drugs in guinea-pigs: KATPopeners and drug-induced QT prolongation

M. Breschi, V. Calderone, S. Sabatini, 2010 .

Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs.

M. Breschi, V. Calderone, S. Sabatini, 2010, The Journal of pharmacy and pharmacology.

A Comprehensive Structural Overview of p38α Mitogen‐Activated Protein Kinase in Complex with ATP‐Site and Non‐ATP‐Site Binders

G. Manfroni, V. Cecchetti, M. Barreca, 2018, ChemMedChem.

Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase

M. Loza, J. Brea, L. Goracci, 2020, European Journal of Medicinal Chemistry.

Synthesis and anti-BVDV activity of acridones as new potential antiviral agents.

E. De Clercq, J. Rozenski, J. Neyts, 2006, Journal of medicinal chemistry.

Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold.

Noreena L. Sweeney, Neerja Kaushik-Basu, D. Frick, 2015, European journal of medicinal chemistry.

6‐Hydrogen‐8‐Methylquinolones Active Against Replicating and Non‐replicating Mycobacterium tuberculosis

S. Franzblau, Marco Pieroni, S. Sabatini, 2012, Chemical biology & drug design.

Synthesis and chromatographic enantioresolution of anti-HIV quinolone derivatives.

B. Natalini, Serena Massari, O. Tabarrini, 2011, Talanta.

Structure–Activity Relationships on Cinnamoyl Derivatives as Inhibitors of p300 Histone Acetyltransferase

L. Altucci, A. Mai, C. Tintori, 2017, ChemMedChem.

Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium.

M. Viveiros, I. Couto, S. Sabatini, 2017, European journal of medicinal chemistry.

Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants.

M. Viveiros, S. Sabatini, G. Manfroni, 2019, ACS infectious diseases.

Effects of KATP openers on the QT prolongation induced by HERG‐blocking drugs in guinea‐pigs

M. Breschi, V. Calderone, S. Sabatini, 2010 .

Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands.

C. Pannecouque, A. Marcello, D. Daelemans, 2014, Bioorganic & medicinal chemistry.

Deciphering the Molecular Recognition Mechanism of Multidrug Resistance Staphylococcus aureus NorA Efflux Pump Using a Supervised Molecular Dynamics Approach

Maicol Bissaro, M. Sturlese, S. Moro, 2019, International journal of molecular sciences.

Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance.

G. Kaatz, S. Sabatini, G. Manfroni, 2013, Journal of medicinal chemistry.

Searching for innovative quinolone-like scaffolds: synthesis and biological evaluation of 2,1-benzothiazine 2,2-dioxide derivatives

G. Kaatz, Marco Pieroni, S. Sabatini, 2012 .

Pyrazolo[4,3-c][1,2]benzothiazines 5,5-dioxide: a promising new class of Staphylococcus aureus NorA efflux pump inhibitors.

E. Carosati, G. Kaatz, M. Villarini, 2012, Journal of medicinal chemistry.

Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump.

G. Kaatz, S. Sabatini, D. Patel, 2011, Journal of medicinal chemistry.

New Pyrazolobenzothiazine Derivatives as Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors

C. Zamperini, E. Dreassi, Neerja Kaushik-Basu, 2014, Journal of medicinal chemistry.

Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones

Matteo Tiecco, G. Manfroni, V. Cecchetti, 2018, European Journal of Organic Chemistry.

Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity

J. Neyts, D. Schols, E. Tramontano, 2022, ACS medicinal chemistry letters.

C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

D. Pietrella, S. Sabatini, G. Manfroni, 2020, Journal of enzyme inhibition and medicinal chemistry.

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions.

V. Calderone, M. Novelli, P. Masiello, 2013, Journal of medicinal chemistry.

Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivatives.

L. Goracci, A. Loregian, Giulio Nannetti, 2017, Organic & biomolecular chemistry.

Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors.

G. Kaatz, D. Pietrella, S. Sabatini, 2017, Journal of medicinal chemistry.

Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity.

L. Goracci, G. Palù, A. Loregian, 2017, European journal of medicinal chemistry.

A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits.

L. Goracci, G. Cruciani, G. Palù, 2015, Journal of medicinal chemistry.

Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors.

D. Rauh, G. Manfroni, V. Cecchetti, 2019, Biochemical and biophysical research communications.

From Quinoline to Quinazoline‐Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search

S. Sabatini, G. Manfroni, Serena Massari, 2021, ChemMedChem.

Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors

S. Sabatini, G. Manfroni, Serena Massari, 2020, International journal of molecular sciences.

Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers.

Roberto Spogli, V. Calderone, S. Sabatini, 2008, Journal of medicinal chemistry.

New Insights On KCA3.1 Channel Modulation.

R. Iannitti, G. Manfroni, V. Cecchetti, 2020, Current pharmaceutical design.

6-Aminoquinolones: photostability, cellular distribution and phototoxicity.

G. Viola, S. Dall’Acqua, D. Vedaldi, 2004, Toxicology in vitro : an international journal published in association with BIBRA.

In vitro phototoxic properties of new 6-desfluoro and 6-fluoro-8-methylquinolones.

G. Viola, F. Dall'acqua, D. Vedaldi, 2002, Toxicology in vitro : an international journal published in association with BIBRA.

p38α MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening

S. Sabatini, V. Cecchetti, M. Barreca, 2015, Molecules.

Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor.

M. Bolognesi, G. Quérat, G. Manfroni, 2016, Antiviral research.

Tumour cell population growth inhibition and cell death induction of functionalized 6‐aminoquinolone derivatives

L. Altucci, G. Manfroni, O. Tabarrini, 2015, Cell proliferation.

Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents.

S. Vasudevan, S. Alonso, S. Sabatini, 2020, European journal of medicinal chemistry.

Velnacrine thiaanalogues as potential agents for treating Alzheimer's disease.

O. Tabarrini, V. Cecchetti, A. Fravolini, 2001, Bioorganic & medicinal chemistry.

Structural Investigation of the Naphthyridone Scaffold: Identification of a 1,6‐Naphthyridone Derivative with Potent and Selective Anti‐HIV Activity

C. Pannecouque, D. Daelemans, S. Sabatini, 2011, ChemMedChem.

Structure modifications of 6-aminoquinolones with potent anti-HIV activity.

E. De Clercq, C. Pannecouque, M. Palumbo, 2004, Journal of medicinal chemistry.

The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.

Neerja Kaushik-Basu, J. Neyts, P. Leyssen, 2014, Journal of medicinal chemistry.

Design, Synthesis, and Evaluation of WC5 Analogues as Inhibitors of Human Cytomegalovirus Immediate‐Early 2 Protein, a Promising Target for Anti‐HCMV Treatment

C. Pannecouque, G. Palù, A. Loregian, 2013, ChemMedChem.

6-Aminoquinolones: a new class of quinolone antibacterials?

G. Cruciani, S. Clementi, O. Tabarrini, 1995, Journal of medicinal chemistry.

Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase.

G. Maga, J. Neyts, P. Leyssen, 2012, Bioorganic & medicinal chemistry.

Dibenzo[1,6]naphthyridindiones as modified quinolone antibacterials

S. Sabatini, O. Tabarrini, V. Cecchetti, 1998 .

2‐Phenylquinolones as Inhibitors of the HIV‐1 Tat–TAR Interaction

B. Gatto, M. Palumbo, S. Sabatini, 2009, ChemMedChem.

A 1,8-naphthyridone derivative targets the HIV-1 Tat-mediated transcription and potently inhibits the HIV-1 replication.

C. Pannecouque, A. Knezevich, A. Marcello, 2010, Journal of medicinal chemistry.

Computer‐Aided Design, Synthesis and Validation of 2‐Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti‐HIV‐1 Tat‐Mediated Transcription Activity

C. Pannecouque, A. Marcello, S. Sabatini, 2013, ChemMedChem.

7-(Disubstituted thiazolyl)-3,5-dihydroxy-6-heptenoic/heptanoic acid derivatives as HMG-CoA reductase inhibitors.

O. Tabarrini, V. Cecchetti, A. Fravolini, 1994, Bioorganic & medicinal chemistry.

Synthesis and antibacterial evaluation of [1,3]benzothiazino[3,2-a]quinoline- and [3,1]benzothiazino[1,2-a]quinoline-6-carboxylic acid derivatives.

G. Cruciani, O. Tabarrini, V. Cecchetti, 1997, Bioorganic & medicinal chemistry.

Chemometric studies on the bactericidal activity of quinolones via an extended VolSurf approach.

R. Mannhold, Giovanni Cianchetta, G. Cruciani, 2004, Journal of medicinal chemistry.

Potent 6-desfluoro-8-methylquinolones as new lead compounds in antibacterial chemotherapy.

M. Palumbo, O. Tabarrini, V. Cecchetti, 1996, Journal of medicinal chemistry.

Structure-activity relationship study on anti-HIV 6-desfluoroquinolones.

C. Pannecouque, J. Balzarini, D. Daelemans, 2008, Journal of medicinal chemistry.

6-Aminoquinolones as new potential anti-HIV agents.

S. Moro, B. Gatto, T. Pecere, 2000, Journal of medicinal chemistry.

New 1,8-peri-annelated tricyclic quinolone antibacterials

O. Tabarrini, V. Cecchetti, A. Fravolini, 2000 .

Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3‐Phenyl‐1,4‐benzothiazine Analogues

G. Kaatz, B. Schindler, S. Sabatini, 2017, ChemMedChem.

1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity

C. Pannecouque, E. Tramontano, S. Sabatini, 2020, Molecules.

Design and synthesis of modified quinolones as antitumoral acridones.

S. Sabatini, H. Miao, O. Tabarrini, 1999, Journal of medicinal chemistry.

Quinolonecarboxylic acids. 2. Synthesis and antibacterial evaluation of 7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acids.

G. Segre, V. Cecchetti, A. Fravolini, 1987, Journal of medicinal chemistry.

Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions.

A. Marcello, G. Quérat, S. Sabatini, 2019, Antiviral research.

Studies on 6-aminoquinolones: synthesis and antibacterial evaluation of 6-amino-8-ethyl- and 6-amino-8-methoxyquinolones.

S. Sabatini, H. Miao, O. Tabarrini, 1999, Bioorganic & medicinal chemistry.

Chemometric methodologies in a quantitative structure-activity relationship study: the antibacterial activity of 6-aminoquinolones.

G. Cruciani, S. Clementi, M. Clementi, 1997, Journal of medicinal chemistry.

Studies on 6-aminoquinolones: synthesis and antibacterial evaluation of 6-amino-8-methylquinolones.

O. Tabarrini, V. Cecchetti, A. Fravolini, 1996, Journal of medicinal chemistry.

1,4-Benzothiazine-2-carboxylic acid 1-oxides as analogues of antibacterial quinolones †

O. Tabarrini, V. Cecchetti, A. Fravolini, 1992 .

Dibenzo[1,6]naphthyridinediones as Modified Quinolone Antibacterials.

S. Sabatini, O. Tabarrini, V. Cecchetti, 1999 .

Binding studies and GRIND/ALMOND-based 3D QSAR analysis of benzothiazine type K(ATP)-channel openers.

Stefano Sabatini, Raimund Mannhold, Emanuele Carosati, 2005, Bioorganic & medicinal chemistry.

Synthesis of 2‐(Arylamino)ethanethiols via Lewis Acid Catalyzed Aminolysis of 2,2‐Dimethylthiirane as Precursors of the 1,4‐Benzothiazine Nucleus.

Roberto Spogli, S. Sabatini, G. Manfroni, 2009 .

The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen‐Activated Protein Kinase Inhibitors

M. Loza, J. Brea, S. Laufer, 2015, Chemical biology & drug design.

Synthesis and biological evaluation of 2-phenylquinolones targeted at Tat/TAR recognition.

B. Gatto, M. Palumbo, C. Del Vecchio, 2009, Bioorganic & medicinal chemistry letters.

Highly potent 1,4-benzothiazine derivatives as K(ATP)-channel openers.

Roberto Spogli, V. Calderone, S. Sabatini, 2003, Journal of medicinal chemistry.

(1,4-Benzothiazinyloxy)alkylpiperazine derivatives as potential antihypertensive agents.

O. Tabarrini, V. Cecchetti, A. Fravolini, 2000, Bioorganic & medicinal chemistry letters.

o-Chlorobenzenesulfonamidic derivatives of (aryloxy)propanolamines as beta-blocking/diuretic agents.

G. Segre, O. Tabarrini, V. Cecchetti, 1993, Journal of medicinal chemistry.

Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors.

J. Handzlik, A. Bojarski, G. Satała, 2020, European journal of medicinal chemistry.

Mg(2+)-mediated binding of 6-substituted quinolones to DNA: relevance to biological activity.

B. Gatto, M. Palumbo, M. Andreolli, 1998, Bioorganic & medicinal chemistry.

6-desfluoroquinolones as HIV-1 Tat-mediated transcription inhibitors.

Oriana Tabarrini, Violetta Cecchetti, Serena Massari, 2010, Future medicinal chemistry.

The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein

B. Gatto, M. Palumbo, G. Palù, 2010, Antimicrobial Agents and Chemotherapy.

Studies on anti-HIV quinolones: new insights on the C-6 position.

C. Pannecouque, D. Daelemans, S. Sabatini, 2009, Bioorganic & medicinal chemistry.

A 6-Aminoquinolone Compound, WC5, with Potent and Selective Anti-Human Cytomegalovirus Activity

G. Palù, A. Loregian, B. Mercorelli, 2008, Antimicrobial Agents and Chemotherapy.

Novel In Vivo Model for the Study of Human Immunodeficiency Virus Type 1 Transcription Inhibitors: Evaluation of New 6-Desfluoroquinolone Derivatives

E. De Clercq, C. Pannecouque, E. Verbeken, 2007, Antimicrobial Agents and Chemotherapy.

2 A NOVEL IN VIVO MODEL FOR THE STUDY OF HIV-1 3 TRANSCRIPTION INHIBITORS : EVALUATION OF NEW 4 6-DESFLUOROQUINOLONE DERIVATIVES ( 6-DFQs ) 5

C. Pannecouque, E. Verbeken, J. Balzarini, 2007 .

HIV-1 transcription in vivo-1-1 2 A NOVEL IN VIVO MODEL FOR THE STUDY OF HIV-1 3 TRANSCRIPTION INHIBITORS : EVALUATION OF NEW 4 6-DESFLUOROQUINOLONE DERIVATIVES ( 6-DFQs ) 5 6 7

C. Pannecouque, E. Verbeken, J. Balzarini, 2007 .

Effects of Novel 6-Desfluoroquinolones and Classic Quinolones on Pentylenetetrazole-Induced Seizures in Mice

G. De Sarro, A. De Sarro, O. Tabarrini, 1999, Antimicrobial Agents and Chemotherapy.

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

C. Pannecouque, E. Tramontano, S. Sabatini, 2018, Journal of enzyme inhibition and medicinal chemistry.

Studies on Cycloheptathiophene‐3‐carboxamide Derivatives as Allosteric HIV‐1 Ribonuclease H Inhibitors

C. Pannecouque, E. Tramontano, S. Sabatini, 2016, ChemMedChem.

Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly.

L. Goracci, G. Cruciani, G. Palù, 2013, Journal of medicinal chemistry.

Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation.

E. De Clercq, C. Pannecouque, J. Balzarini, 2005, The Journal of antimicrobial chemotherapy.

Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation

M. Nocchetti, D. Pietrella, R. Pagiotti, 2017 .

Synthesis and antibacterial evaluation of 1,4-thiazinoquinoline-carboxylic acids

V. Cecchetti, A. Fravolini, F. Schiaffella, 1984 .

In vitro activities of new quinolones against Helicobacter pylori

E. Losi, G. Teti, V. Cusumano, 1997, Antimicrobial agents and chemotherapy.

Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase.

S. Vasudevan, S. Sabatini, G. Manfroni, 2020, ACS medicinal chemistry letters.

Comparative In Vitro Anti-Hepatitis C Virus Activities of a Selected Series of Polymerase, Protease, and Helicase Inhibitors

P. Herdewijn, R. Bartenschlager, J. Neyts, 2008, Antimicrobial Agents and Chemotherapy.

New heterocyclic ring systems. XIII. 7,11-Dithiaazasteroid analogues†‡

V. Cecchetti, A. Fravolini, F. Schiaffella, 1982 .

Accounting for Target Flexibility and Water Molecules by Docking to Ensembles of Target Structures: The HCV NS5B Palm Site I Inhibitors Case Study

Stefano Sabatini, M. Letizia Barreca, Nunzio Iraci, 2014, J. Chem. Inf. Model..

Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development.

Nunzio Iraci, Giuseppe Manfroni, Violetta Cecchetti, 2011, Future medicinal chemistry.

Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs

G. Manfroni, V. Cecchetti, T. Felicetti, 2020, Journal of medicinal chemistry.

New Anti-Human Immunodeficiency Virus Type 1 6-Aminoquinolones: Mechanism of Action

B. Gatto, T. Pecere, M. Palumbo, 2003, Antimicrobial Agents and Chemotherapy.

A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors

G. Manfroni, V. Cecchetti, M. Barreca, 2015, ChemMedChem.

Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents.

O. Cevik, Neerja Kaushik-Basu, D. Frick, 2016, European journal of medicinal chemistry.

A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates.

G. Manfroni, V. Cecchetti, M. Barreca, 2016, Journal of medicinal chemistry.

New heterocyclic ring systems. XI. Azadithiasteroid analogues

V. Cecchetti, A. Fravolini, F. Schiaffella, 1979 .

Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells

S. Bicciato, U. Grohmann, G. Mondanelli, 2019, Front. Immunol..

Pharmacological Agents Targeting the Cellular Prion Protein

V. Cecchetti, M. Barreca, N. Iraci, 2018, Pathogens.

Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position.

G. Kaatz, B. Schindler, S. Sabatini, 2018, European journal of medicinal chemistry.

The "racemic approach" in the evaluation of the enantiomeric NorA efflux pump inhibition activity of 2-phenylquinoline derivatives.

G. Kaatz, W. Lindner, B. Natalini, 2016, Journal of Pharmaceutical and Biomedical Analysis.

QSAR study and VolSurf characterization of anti-HIV quinolone library

Gabriele Cruciani, Oriana Tabarrini, Violetta Cecchetti, 2001, J. Comput. Aided Mol. Des..

Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation.

M. Loza, J. Brea, S. Laufer, 2019, European journal of medicinal chemistry.

Ethyl 1,8-naphthyridone-3-carboxylates downregulate human papillomavirus-16 E6 and E7 oncogene expression.

A. Loregian, R. Cavalli, D. Lembo, 2014, Journal of medicinal chemistry.

Broad‐Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View

G. Manfroni, V. Cecchetti, R. Cannalire, 2020, ChemMedChem.

Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes.

S. Vasudevan, S. Alonso, S. Sabatini, 2023, European journal of medicinal chemistry.

2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction.

K. Kieć‐Kononowicz, G. Kaatz, D. Pietrella, 2018, Journal of medicinal chemistry.

Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase.

G. Quérat, S. Sabatini, G. Manfroni, 2018, European journal of medicinal chemistry.

Studies of Anti‐HIV Transcription Inhibitor Quinolones: Identification of Potent N1‐Vinyl Derivatives

C. Pannecouque, B. Gatto, M. Palumbo, 2010, ChemMedChem.

Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener.

C. Bertucci, B. Natalini, G. Manfroni, 2014, Journal of chromatography. A.

Chemometric rationalization of the structural and physicochemical basis for selective cyclooxygenase-2 inhibition: Toward more specific ligands

Oriana Tabarrini, Violetta Cecchetti, Enrica Filipponi, 2000, J. Comput. Aided Mol. Des..

New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains.

S. Sabatini, G. Manfroni, Serena Massari, 2022, European journal of medicinal chemistry.

Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication.

Neerja Kaushik-Basu, Stefano Sabatini, Jan Paeshuyse, 2013, Journal of medicinal chemistry.

Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy

L. Nencioni, J. Hiscott, Mariangela Agamennone, 2023, International journal of molecular sciences.

Inhibition of Influenza Virus Polymerase by Interfering with Its Protein–Protein Interactions

Serena Massari, O. Tabarrini, V. Cecchetti, 2020, ACS infectious diseases.

Triazolopyrimidine Nuclei: Privileged Scaffolds for Developing Antiviral Agents with a Proper Pharmacokinetic Profile.

Serena Massari, O. Tabarrini, V. Cecchetti, 2021, Current Medicinal Chemistry.

In Vitro Activity of MF 5137, a New Potent 6-Aminoquinolone

O. Tabarrini, V. Cecchetti, A. Fravolini, 2012, Drugs.

1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors.

A. Loregian, J. Neyts, Serena Massari, 2021, European journal of medicinal chemistry.

Symbiotic approach to drug design : N-[(4-chloro-3-sulfamoylbenzamido)-ethyl]propanolamine derivatives as β-adrenergic blocking agents with diuretic activity

A. Goi, O. Tabarrini, V. Cecchetti, 1991 .

A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits.

G. Cruciani, G. Palù, A. Loregian, 2015, Journal of medicinal chemistry.

Computer‐Aided Design, Synthesis and Validation of 2‐Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti‐HIV‐1 Tat‐Mediated Transcription Activity

C. Pannecouque, A. Marcello, S. Sabatini, 2013, ChemMedChem.

Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3‐Phenyl‐1,4‐benzothiazine Analogues

G. Kaatz, B. Schindler, S. Sabatini, 2017, ChemMedChem.