G. Pál

发表

Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis.

Sachdev S Sidhu, Anthony A Kossiakoff, M. Ultsch, 2005, Journal of molecular biology.

A redesigned genetic code for selective labeling in protein NMR.

Z. Gáspári, A. Perczel, G. Pál, 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.

MASP-1 Increases Endothelial Permeability

Z. Nemeth, P. Gál, Z. Doleschall, 2019, Front. Immunol..

Mapping Hidden Potential Identity Elements by Computing the Average Discriminating Power of Individual tRNA Positions

G. Pál, Áron Szenes, 2012, DNA research : an international journal for rapid publication of reports on genes and genomes.

In silico detection of tRNA sequence features characteristic to aminoacyl-tRNA synthetase class membership

E. Szathmáry, Á. Kun, É. Jakó, 2007, Nucleic acids research.

Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1 associated membranous nephropathy.

D. Salant, P. Gál, R. Wüthrich, 2020, The Journal of clinical investigation.

Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation

M. Wilmanns, P. Gál, Z. Nagy, 2022, The Journal of biological chemistry.

MASP-1 of the complement system alters fibrinolytic behaviour of blood clots.

P. Gál, J. Dobó, V. Schroeder, 2019, Molecular immunology.

Affinity purification of recombinant trypsinogen using immobilized ecotin.

M. Sahin-Tóth, G. Pál, Z. Lengyel, 1998, Protein expression and purification.

Alteration of the specificity of ecotin, an E. coli serine proteinase inhibitor, by site directed mutagenesis

L. Gráf, A. Patthy, G. Pál, 1994, FEBS letters.

Arg236 in human chymotrypsin B2 (CTRB2) is a key determinant of high enzyme activity, trypsinogen degradation capacity, and protection against pancreatitis.

M. Sahin-Tóth, G. Pál, Gitta Schlosser, 2022, Biochimica et biophysica acta. Proteins and proteomics.

Proprotein Convertase Is the Highest-Level Activator of the Alternative Complement Pathway in the Blood

P. Gál, P. Závodszky, H. Farkas, 2021, The Journal of Immunology.

Methods for the construction of phage-displayed libraries

Frederic A. Fellouse, G. Pál, 2005 .

Cholesterol crystals activate the lectin complement pathway via ficolin-2 and MBL - implications for the progression of atherosclerosis

P. Gál, P. Aukrust, T. Espevik, 2016, The Journal of Immunology.

Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis

P. Gál, P. Aukrust, T. Espevik, 2016, The Journal of Immunology.

Mannose-Binding Lectin : Implications for Complement Pathway via Ficolin-2 and Cholesterol Crystals Activate the Lectin

P. Gál, P. Aukrust, T. Espevik, 2016 .

Human Cationic Trypsinogen

M. Tóth, M. Sahin-Tóth, G. Pál, 2002, The Journal of Biological Chemistry.

High Affinity Small Protein Inhibitors of Human Chymotrypsin C (CTRC) Selected by Phage Display Reveal Unusual Preference for P4′ Acidic Residues*

E. Radisky, A. Szabó, M. Sahin-Tóth, 2011, The Journal of Biological Chemistry.

Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes*

A. Szabó, M. Sahin-Tóth, E. Boros, 2017, The Journal of Biological Chemistry.

Two mutations in rat trypsin confer resistance against autolysis.

É. Várallyay, L. Gráf, L. Szilágyi, 1998, Biochemical and biophysical research communications.

Specificity assay of serine proteinases by reverse-phase high-performance liquid chromatography analysis of competing oligopeptide substrate library.

L. Gráf, A. Patthy, G. Pál, 2001, Analytical biochemistry.

Proteinase inhibitors from desert locust, Schistocerca gregaria: engineering of both P(1) and P(1)' residues converts a potent chymotrypsin inhibitor to a potent trypsin inhibitor.

É. Várallyay, L. Gráf, K. Vékey, 1999, Biochimica et biophysica acta.

Quantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin Pathway*

P. Gál, P. Závodszky, K. Szilágyi, 2013, The Journal of Biological Chemistry.

The emerging roles of mannose‐binding lectin‐associated serine proteases (MASPs) in the lectin pathway of complement and beyond

P. Gál, L. Cervenak, J. Dobó, 2016, Immunological reviews.

Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2

P. Gál, P. Závodszky, K. Szilágyi, 2012, Proceedings of the National Academy of Sciences.

Functional promiscuity of squirrel monkey growth hormone receptor toward both primate and nonprimate growth hormones.

Wen-Hsiung Li, S. Yi, A. Kossiakoff, 2002, Molecular biology and evolution.

Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors

P. Gál, R. Szász, G. Pál, 2019, The Journal of Biological Chemistry.

MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked

P. Gál, P. Závodszky, R. Szász, 2016, Scientific Reports.

Mutant rat trypsin selectively cleaves tyrosyl peptide bonds.

L. Gráf, A. Patthy, G. Pál, 2004, Analytical biochemistry.

Inhibition of the serine proteases of the complement system.

P. Gál, P. Závodszky, J. Dobó, 2013, Advances in experimental medicine and biology.

Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum

P. Gál, Z. Nagy, E. Boros, 2019, PLoS pathogens.

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2*

M. Wilmanns, P. Gál, P. Závodszky, 2012, The Journal of Biological Chemistry.

Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides

Annamária F. Ángyán, Z. Gáspári, P. Gál, 2022, ACS chemical biology.

Directed Evolution of Canonical Loops and Their Swapping between Unrelated Serine Proteinase Inhibitors Disprove the Interscaffolding Additivity Model.

J. Kardos, E. Boros, G. Pál, 2019, Journal of molecular biology.

DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond

G. Pál, L. Nyitray, L. Radnai, 2011, The FEBS journal.

Novel linear motif filtering protocol reveals the role of the LC8 dynein light chain in the Hippo pathway

Zsuzsanna Dosztányi, Gábor Erdös, Gábor Pál, 2017, PLoS Comput. Biol..

MASP-1 and MASP-2 Do Not Activate Pro–Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors

M. Ueffing, S. Dammeier, P. Gál, 2016, The Journal of Immunology.

Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome

Gergely Katona, László Nyitray, W. Y. Wahlgren, 2011, PloS one.

The first semi-synthetic serine protease made by native chemical ligation.

A. Kossiakoff, Wuyuan Lu, G. Pál, 2003, Protein expression and purification.

The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: insights into the mechanisms responsible for improved affinity.

A. Kossiakoff, S. Sidhu, G. Pál, 2003, Journal of molecular biology.

Directed Evoluti Loops and Their Unrelated Serine Inhibitors Dispro

David He, J. Kardos, E. Boros, 2019 .

When the surface tells what lies beneath: combinatorial phage-display mutagenesis reveals complex networks of surface-core interactions in the pacifastin protease inhibitor family.

L. Gráf, Z. Gáspári, A. Patthy, 2007, Journal of molecular biology.

Structural determinants governing S100A4‐induced isoform‐selective disassembly of nonmuscle myosin II filaments

L. Kalmár, G. Pál, L. Nyitray, 2016, The FEBS journal.

The Catalytic Aspartate Is Protonated in the Michaelis Complex Formed between Trypsin and an in Vitro Evolved Substrate-like Inhibitor

W. Y. Wahlgren, G. Katona, L. Gráf, 2010, The Journal of Biological Chemistry.

Selective Inhibition of the Lectin Pathway of Complement with Phage Display Selected Peptides against Mannose-Binding Lectin-Associated Serine Protease (MASP)-1 and -2: Significant Contribution of MASP-1 to Lectin Pathway Activation

P. Gál, P. Závodszky, Júlia Balczer, 2010, The Journal of Immunology.

to Lectin Pathway Activation Significant Contribution of MASP-1 Serine Protease (MASP)-1 and -2: Mannose-Binding Lectin-Associated Display Selected Peptides against Pathway of Complement with Phage Selective Inhibition of the Lectin

P. Gál, Júlia Balczer, R. Szász, 2010 .

Lectin Pathway Activation and-2 : Significant Contribution of MASP-1 Lectin-Associated Serine Protease ( MASP )-1 Peptides against Mannose-Binding Complement with Phage Display Selected

P. Gál, P. Závodszky, Júlia Balczer, 2010 .

Comprehensive and Quantitative Mapping of Energy Landscapes for Protein-Protein Interactions by Rapid Combinatorial Scanning*♦

Sachdev S Sidhu, Gábor Pál, Jean-Louis K Kouadio, 2006, Journal of Biological Chemistry.

Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis

Sachdev S Sidhu, Anthony A Kossiakoff, A. Kossiakoff, 2005, Protein science : a publication of the Protein Society.

Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization

Anthony A Kossiakoff, A. Kossiakoff, G. Pál, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Reexamination of the recognition preference of the specificity pocket of the Abl SH3 domain

Wuyuan Lu, G. Pál, Zhibin Wu, 2003, Journal of molecular recognition : JMR.

Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model

W. Lam, P. Gál, Murielle Golomingi, 2022, Frontiers in Immunology.

MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model

W. Lam, P. Gál, J. Dobó, 2018, PloS one.

Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation

P. Gál, P. Závodszky, J. Dobó, 2018, The Journal of Immunology.

Shotgun Alanine Scanning Shows That Growth Hormone Can Bind Productively to Its Receptor through a Drastically Minimized Interface*

James R Horn, Jean-Louis K Kouadio, Anthony A Kossiakoff, 2005, Journal of Biological Chemistry.

Substrate specificity of human chymotrypsin-like protease (CTRL) characterized by phage display-selected small-protein inhibitors.

G. Pál, Gitta Schlosser, E. Hegyi, 2023, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels

Murielle Golomingi, J. Dobó, G. Pál, 2023, Frontiers in immunology.

Comprehensive and Quantitative Mapping of Energy Landscapes for Protein-Protein Interactions by Rapid Combinatorial Scanning*♦

A. Kossiakoff, S. Sidhu, G. Pál, 2006, Journal of Biological Chemistry.