A. Tighe

发表

p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit

Stephen S. Taylor, Pablo Lara-Gonzalez, Frederick G. Westhorpe, 2011, Journal of Cell Science.

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Stephen S. Taylor, V. L. Johnson, N. Keen, 2003, The Journal of cell biology.

Classification of ovarian cancer cell lines using transcriptional profiles defines the five major pathological subtypes

A. Tighe, Louisa Nelson, S. Taylor, 2020, bioRxiv.

Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1

Stephen S. Taylor, D. Zheleva, A. Tighe, 2015, Oncotarget.

Inhibition of Bcl-xL sensitizes cells to mitotic blockers, but not mitotic drivers

Stephen S. Taylor, A. Tighe, Louisa Nelson, 2016, Open Biology.

Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models

Stephen S. Taylor, D. Spierings, F. Foijer, 2021, Journal of Experimental & Clinical Cancer Research.

Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models

Stephen S. Taylor, D. Spierings, F. Foijer, 2021, Journal of experimental & clinical cancer research : CR.

Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes

Stephen S. Taylor, G. Burghel, I. Lin, 2021, Genome medicine.

MYC Is a Major Determinant of Mitotic Cell Fate

Stephen S. Taylor, Ying Sun, O. Sansom, 2015, Cancer cell.

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

Stephen S. Taylor, G. Jayson, D. Spierings, 2020, Nature Communications.

Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex

Andrea Musacchio, Stephen Green, Stephen S. Taylor, 2010, The Journal of cell biology.

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

Andrea Musacchio, Stephen S. Taylor, A. Musacchio, 2010, The Journal of cell biology.

Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores

Stephen S. Taylor, A. Tighe, O. Staples, 2008, The Journal of cell biology.

Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F

Stephen S. Taylor, M. Malumbres, R. Wolthuis, 2010, Journal of Cell Science.

Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy

Stephen S. Taylor, Sarah L. Thompson, A. Tighe, 2015, Oncotarget.

Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability

Stephen S. Taylor, V. L. Johnson, A. Tighe, 2004, Journal of Cell Science.

TP53 loss initiates chromosomal instability in fallopian tube epithelial cells

Stephen S. Taylor, T. Ried, A. Nussenzweig, 2021, Disease models & mechanisms.

Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors

Stephen S. Taylor, A. Tighe, Louisa Nelson, 2022, NAR cancer.

TP53 loss initiates chromosomal instability in high-grade serous ovarian cancer

Stephen S. Taylor, T. Ried, A. Nussenzweig, 2021, bioRxiv.

GSK-3 inhibitors induce chromosome instability

Stephen S. Taylor, A. Tighe, O. Staples, 2007, BMC Cell Biology.

Aneuploid colon cancer cells have a robust spindle checkpoint

Stephen S. Taylor, V. L. Johnson, M. Albertella, 2001, EMBO reports.

The p 38 alpha Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1 alpha

Stephen S. Taylor, D. Spierings, P. Townsend, 2018 .

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

Stephen S. Taylor, P. Townsend, Sarah L. Thompson, 2018, Cell reports.

The p38a Stress Kinase Su ppresses Aneuploidy Tolerance by Inhibiting Hif-1a

Stephen S. Taylor, P. Townsend, Sarah L. Thompson, 2018 .

Re-evaluating the role of Tao1 in the spindle checkpoint

Stephen S. Taylor, Frederick G. Westhorpe, A. Tighe, 2010, Chromosoma.

Mps 1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad 2 to kinetochores

Stephen S. Taylor, A. Tighe, O. Staples, 2008 .

Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20

Stephen S. Taylor, V. L. Johnson, Maria I F Scott, 2005, Journal of Cell Science.

Inhibitors of the Bub1 spindle assembly checkpoint kinase: synthesis of BAY-320 and comparison with 2OH-BNPP1

Stephen S. Taylor, A. Tighe, D. Procter, 2020, bioRxiv.

DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors

Stephen S. Taylor, D. Spierings, D. Jackson, 2019, Cancer cell.

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

Stephen S. Taylor, G. Jayson, D. Spierings, 2020, Nature Communications.

Sustained Mps 1 activity is required in mitosis to recruit O-Mad 2 to the Mad 1 – C-Mad 2 core complex

Andrea Musacchio, Stephen Green, Stephen S. Taylor, 2010 .

Exploiting a living biobank to delineate mechanisms underlying disease-specific chromosome instability

Stephen S. Taylor, A. Tighe, Louisa Nelson, 2023, Chromosome Research.

Inhibition of Bcl-xL sensitizes cells to mitotic blockers, but not mitotic drivers

Stephen S. Taylor, A. Tighe, Louisa Nelson, 2016, Open Biology.

Inhibition of Bcl-xL sensitizes cells to mitotic blockers , but not mitotic drivers

Stephen S. Taylor, A. Tighe, Louisa Nelson, 2016 .

Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex

Stephen S. Taylor, A. Musacchio, S. Green, 2010, The Journal of cell biology.

Mitochondrial Targeting of Adenomatous Polyposis Coli Protein Is Stimulated by Truncating Cancer Mutations

Stephen S. Taylor, M. T. Mok, Y. Lei, 2008, Journal of Biological Chemistry.

Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1

A. Tighe, Claire F. Aspinall, Stephen S. Taylor, 2015, Oncotarget.