C. Dunham

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Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

Michael Brudno, Jennifer Chan, Uri Tabori, 2014, Nature Genetics.

The role of resection alone in select children with intracranial ependymoma: the Canadian Pediatric Brain Tumour Consortium experience

D. Johnston, S. Yip, D. Eisenstat, 2014, Child's Nervous System.

Microfibrillar collagen hemostat-induced necrotizing granulomatous inflammation developing after craniotomy: a pediatric case series.

P. Steinbok, C. Dunham, L. Apel-Sarid, 2010, Journal of neurosurgery. Pediatrics.

Fatal Congenital Hypertrophic Cardiomyopathy and a Pancreatic Nodule Morphologically Identical to Focal Lesion of Congenital Hyperinsulinism in an Infant with Costello Syndrome: Case Report and Review of the Literature

S. Yip, Millan S Patel, E. Ruchelli, 2015, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Comparative RNA-Sequencing Analysis Benefits a Pediatric Patient With Relapsed Cancer

Steven J. M. Jones, Joshua M. Stuart, D. Haussler, 2018, JCO precision oncology.

Primary Intracerebral Angiomatoid Fibrous Histiocytoma: Report of a Case With a t(12;22)(q13;q12) Causing Type 1 Fusion of the EWS and ATF-1 Genes

J. Pfeifer, A. Perry, C. Dunham, 2008, The American journal of surgical pathology.

A case series of pediatric survivors of anaplastic pleomorphic xanthoastrocytoma

S. Yip, G. Zadeh, K. Goddard, 2021, Neuro-oncology advances.

Pontine Embryonal Tumor With Multilayered Rosettes: An Autopsy Case Exhibiting Extensive Posttreatment Glial and Neuronal Maturation

J. Hukin, C. Dunham, A. Levine, 2020, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas

Arun K. Ramani, M. Shago, D. Johnston, 2019, Nature Communications.

Imaging , Diagnosis , Prognosis Array-Based Comparative Genomic Hybridization Identifies CDK 4 and FOXM 1 Alterations as Independent Predictors of Survival in Malignant Peripheral Nerve Sheath Tumor

B. Scheithauer, M. Watson, J. Payton, 2011 .

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

T. Hortobágyi, J. Olson, R. McLendon, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hypotonia and Infantile Spasms: A New Phenotype of Coenzyme Q10 Deficiency?

C. Dunham, E. Lemire, R. Huntsman, 2009, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma

David T. W. Jones, R. McLendon, S. Croul, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Loss of BRG1 (SMARCA4) Immunoexpression in a Pediatric Non-Central Nervous System Tumor Cohort

L. Armstrong, C. Dunham, T. Ng, 2020, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Infant brain tumors: a neuropathologic population-based institutional reappraisal.

P. Steinbok, C. Dunham, S. Pillai, 2012, Human pathology.

West Nile Virus-Induced Neuroinflammation: Glial Infection and Capsid Protein-Mediated Neurovirulence

C. Power, T. Hobman, W. Halliday, 2007, Journal of Virology.

West Nile Virus-induced neuroinflammation: glial infection and capsid

C. Power, T. Hobman, W. Halliday, 2007 .

Pathologic Skull Fracture in a Near-Term Neonate with Arthrochalasia Type Ehlers-Danlos Syndrome: A Case Report

A. Solimano, C. Dunham, Anna F. Lee, 2020, Fetal and pediatric pathology.

Trametinib therapy for children with neurofibromatosis type 1 and life‐threatening plexiform neurofibroma or treatment‐refractory low‐grade glioma

J. Ludemann, D. Wensley, S. Rassekh, 2021, Cancer medicine.

Cerebellar cavernous malformation in pediatric patients: defining clinical, neuroimaging, and therapeutic characteristics.

P. Steinbok, C. Dunham, D. Cochrane, 2015, Journal of neurosurgery. Pediatrics.

Congenital stridor in the context of Chiari malformation type II: the etiological role of vernix caseosa granulomatous meningitis.

P. Steinbok, C. Dunham, A. Stritzke, 2011, Journal of neurosurgery. Pediatrics.

MRI Findings in an Immunocompromised Boy with CNS Fungal Infection

E. Wirrell, H. Glass, W. Morrish, 2007, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

Neuroimaging of Fetal Infection

M. L. Rossi, L. Tychsen, M. Recio, 2017, Journal of Pediatric Neurology.

Assessing the accuracy of death records and pre-mortem clinical diagnoses in children diagnosed with brain tumors: A retrospective chart review of children in British Columbia, Canada.

G. Hendson, K. Goddard, A. Lo, 2015, Pathology, research and practice.

Polo‐Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice

H. Wakimoto, S. Yip, Chris Jones, 2012, Stem cells.

High-Grade Gliomas

C. Q. Lee, David T. W. Jones, Michael D. Brooks, 2012, Oxford Medicine Online.

High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival.

B. Kleinschmidt-DeMasters, D. Ashley, Andrea M. Muscat, 2011, Neuro-oncology.

Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome

D. Johnston, M. Kool, S. Yip, 2017, Acta Neuropathologica.

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Mei Lu, Deena M A Gendoo, Gary D Bader, 2016, Cancer cell.

Array-Based Comparative Genomic Hybridization Identifies CDK4 and FOXM1 Alterations as Independent Predictors of Survival in Malignant Peripheral Nerve Sheath Tumor

B. Scheithauer, M. Watson, J. Payton, 2011, Clinical Cancer Research.

Diffuse glioneuronal tumour with oligodendroglioma‐like features and nuclear clusters (DGONC) – a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14

M. Kool, S. Pfister, E. Aronica, 2019, Neuropathology and applied neurobiology.

Heterogeneity within the PF-EPN-B ependymoma subgroup

Martin Sill, Caterina Giannini, Hendrik Witt, 2018, Acta Neuropathologica.

Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children.

S. Yip, P. Northcott, C. Hawkins, 2013, Cancer research.

Overcoming resistance to sonic hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma

C. Hawkins, S. Dunn, Michael D. Taylor, 2014, Pediatric blood & cancer.

Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.

Gary D Bader, D. Johnston, T. Hortobágyi, 2015, The Lancet. Oncology.

Uncommon pediatric tumors of the posterior fossa: pathologic and molecular features

C. Dunham, Christopher Dunham, 2015, Child's Nervous System.

Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

P. Sorensen, M. Kool, S. Pfister, 2021, Clinical Cancer Research.

NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling

Steven J. M. Jones, Adrian B Levine, E. Pleasance, 2021, Clinical case reports.

Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis.

M. Nowaczyk, A. Lehman, B. Maranda, 2016, JCI insight.

Possible differentiation of cerebral glioblastoma into pleomorphic xanthoastrocytoma: an unusual case in an infant.

Stephen Yip, Patrice Eydoux, S. Yip, 2012, Journal of neurosurgery. Pediatrics.

The impact of whole genome and transcriptome analysis (WGTA) on predictive biomarker discovery and diagnostic accuracy of advanced malignancies

Steven J. M. Jones, E. Pleasance, M. Marra, 2022, The journal of pathology. Clinical research.

FoxG1 Interacts with Bmi1 to Regulate Self‐Renewal and Tumorigenicity of Medulloblastoma Stem Cells

C. Hawkins, S. Dunn, Michael D. Taylor, 2013, Stem cells.

Pediatric brain tumors: a histologic and genetic update on commonly encountered entities.

C. Dunham, 2010, Seminars in diagnostic pathology.

Intracranial tumors in infants: long-term functional outcome, survival, and its predictors

P. Steinbok, J. Hukin, C. Dunham, 2012, Child's Nervous System.

EZH2 expression is a prognostic factor in childhood intracranial ependymoma: A Canadian Pediatric Brain Tumor Consortium study

Amanda M Li, D. Johnston, S. Yip, 2015, Cancer.

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes

B. Kleinschmidt-DeMasters, R. Vibhakar, A. Donson, 2013, Pediatric blood & cancer.

Histopathology of the filum terminale in children with and without tethered cord syndrome with attention to the elastic tissue within the filum

G. Hendson, P. Steinbok, C. Dunham, 2016, Child's Nervous System.

Embryonal tumor with abundant neuropil and true rosettes (ETANTR): report of a case with prominent neurocytic differentiation

E. Wills, A. Perry, C. Dunham, 2007, Journal of Neuro-Oncology.

Atypical teratoid/rhabdoid tumor arising in the setting of a pleomorphic xanthoastrocytoma

J. Biegel, A. Judkins, A. Perry, 2007, Journal of Neuro-Oncology.

Atypical Teratoid Rhabdoid Tumors (ATRTs): The British Columbia's Children's Hospital's Experience, 1986–2006

S. Yip, A. Stemmer-Rachamimov, A. Fleming, 2012, Brain pathology.

ATYPICAL TERATOID RHABDOID TUMOR (ATRT)

R. Siebert, K. Ligon, C. Roberts, 2012 .

Diffusion-weighted imaging and pathological correlation in pediatric medulloblastomas—“They are not always restricted!”

D. Cochrane, P. Steinbok, C. Dunham, 2011, Child's Nervous System.

Evolution of a Pediatric Primary Cerebral ALK-1-Positive Anaplastic Large Cell Lymphoma on Serial MRI

S. Rassekh, C. Dunham, A. Singhal, 2015, Pediatric Neurosurgery.

Personalizing the treatment of pediatric medulloblastoma: Polo-Like Kinase 1 (PLK1) as a molecular target for high-risk children.

S. Yip, P. Northcott, C. Hawkins, 2013 .

mTOR Inhibitors as a New Therapeutic Strategy in Treatment Resistant Epilepsy in Hemimegalencephaly: A Case Report

A. Shlien, M. Connolly, C. Dunham, 2018, Journal of child neurology.

Malignant transformation of an intraaxial-supratentorial neurenteric cyst - case report and review of the literature.

C. Dunham, M. Hamilton, B. Curry, 2009, Clinical neuropathology.

Significance of necrosis in grading of oligodendroglial neoplasms: a clinicopathologic and genetic study of newly diagnosed high-grade gliomas.

C. Miller, B. Scheithauer, A. Perry, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Gliosarcoma – Clinico-pathology, Genetics and a Review of Rare Congenital Cases

C. Dunham, 2009 .

Congenital gliosarcoma: detailed clinicopathologic documentation of a rare neoplasm.

H. Osiovich, D. McFadden, C. Dunham, 2009, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Radiological features of infantile glioblastoma and desmoplastic infantile tumors: British Columbia's Children's Hospital experience.

P. Steinbok, C. Dunham, M. Heran, 2015, Journal of neurosurgery. Pediatrics.

Malignant desmoplastic infantile astrocytoma? a case report and review of the literature.

P. Steinbok, C. Dunham, C. Gillis, 2013, Clinical neuropathology.

Phenotypic evolution of UNC80 loss of function

V. Maduro, D. Adams, C. Toro, 2016, American journal of medical genetics. Part A.

Abnormal fatty acid metabolism is a core component of spinal muscular atrophy

M. Bowerman, P. Claus, R. Kothary, 2019, Annals of clinical and translational neurology.

Answer to case of the month # 132. Adult ileocolic intussusception secondary to a submucosal lipoma.

R. Gray, C. Dunham, D. Lautner, 2008, Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes.

Sonographic assessment of normal and abnormal patterns of fetal cerebral lamination

D. Prayer, D. Pugash, G. Hendson, 2012, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

Clinical, imaging, and immunohistochemical characteristics of focal cortical dysplasia Type II extratemporal epilepsies in children: analyses of an institutional case series.

M. Connolly, G. Hendson, P. Steinbok, 2017, Journal of neurosurgery. Pediatrics.

Neuronal Intranuclear Inclusion Disease Presenting as Juvenile Parkinsonism

O. Suchowersky, Katie M. Wiltshire, R. Auer, 2010, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

Characterization of Switch/Sucrose Nonfermenting Complex Proteins and Nestin Expression in a Cohort of Pediatric Central Nervous System Tumors

B. Tessier-Cloutier, L. Armstrong, C. Dunham, 2023, Applied immunohistochemistry & molecular morphology : AIMM.

Congenital Hypothalamic “Hamartoblastoma” Versus “Hamartoma”: Suggestions for Neuropathologic Terminology Emanating From a Mid-gestational Autopsy Case of Pallister-Hall Syndrome

M. McKinnon, D. McFadden, C. Dunham, 2018, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Fetal progeria: prenatal sonographic findings in petty syndrome.

A. Lehman, L. Clarke, D. Pugash, 2013, Journal of ultrasound in medicine.

Fetal Progeria: Prenatal Sonographic Findings in Petty Syndrome

A. Lehman, L. Clarke, D. Pugash, 2013 .

Granulomatous herpes simplex encephalitis in an infant with multicystic encephalopathy: a distinct clinicopathologic entity?

S. Stockler, V. White, C. Dunham, 2014, Pediatric Neurology.

Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas

Mariella G. Filbin, A. Chinnaiyan, M. Kool, 2021, Science Translational Medicine.

Outcomes of a radiation sparing approach in medulloblastoma by subgroup in young children: an institutional review

C. Strahlendorf, S. Yip, J. Finlay, 2023, Child's Nervous System.

A Case of Primary Intracranial Sarcoma, DICER1-Mutant, in a Child with a Germline DICER1 Mutation

C. Dunham, S. Kosteniuk, G. Michaiel, 2023, Brain sciences.

Histologic Correlates of Molecular Group 4 Pediatric Medulloblastoma: A Retrospective Canadian Review

D. Johnston, S. Yip, S. Dunn, 2021, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

High grade gliomas

C. Q. Lee, David T. W. Jones, Michael D. Brooks, 2022, Progress in Brain Research.

Radiological features of infantile glioblastoma and desmoplastic infantile tumors: British Columbia's Children's Hospital experience.

P. Steinbok, C. Dunham, M. Heran, 2015, Journal of Neurosurgery: Pediatrics.

Magnetic resonance imaging in the encephalopathic term newborn.

Steven P. Miller, V. Chau, K. Poskitt, 2014, Current pediatric reviews.

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes

B. Kleinschmidt-DeMasters, A. Donson, N. Foreman, 2013, Pediatric blood & cancer.

Pleomorphic xanthoastrocytoma of the spinal cord: case report and literature review.

S. Yip, S. Das, D. Cochrane, 2014, Clinical neuropathology.