C. Benetatos

发表

Mechanism of action of a pestivirus antiviral compound.

C. Rice, S. Sun, M. Collett, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Small Molecule Therapeutics Birinapant ( TL 32711 ) , a Bivalent SMAC Mimetic , Targets TRAF 2-Associated cIAPs , Abrogates TNF-Induced NFk B Activation , and Is Active in Patient-Derived Xenograft Models

Yigong Shi, G. Kapoor, Y. Mitsuuchi, 2014 .

Increase of βIII- and βIVa-Tubulin Isotypes in Human Prostate Carcinoma Cells as a Result of Estramustine Resistance

K. Tew, G. Hudes, C. Benetatos, 1996 .

Altered beta-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells.

G. Hudes, C. Benetatos, S. Ranganathan, 1998, British Journal of Cancer.

Cloning and sequencing of human betaIII-tubulin cDNA: induction of betaIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents.

G. Hudes, C. Benetatos, S. Ranganathan, 1998, Biochimica et biophysica acta.

RIPK3 promotes cell death NLRP3 inflammasome and interleukin-1 activation in the absence of MLKL

D. Vaux, W. Alexander, I. Wicks, 2017 .

Birinapant, a smac-mimetic with improved tolerability for the treatment of solid tumors and hematological malignancies.

Yigong Shi, G. Kapoor, C. Day, 2014, Journal of medicinal chemistry.

Novel Nonnucleoside Inhibitor of Hepatitis C Virus RNA-Dependent RNA Polymerase

A. Gopalsamy, J. Ellingboe, A. Howe, 2004, Antimicrobial Agents and Chemotherapy.

C Virus RNA-Dependent RNA Polymerase Novel Nonnucleoside Inhibitor of Hepatitis

A. Gopalsamy, J. Ellingboe, A. Howe, 2004 .

Immunohistochemical analysis of β‐tubulin isotypes in human prostate carcinoma and benign prostatic hypertrophy

G. Hudes, C. Benetatos, H. Salazar, 1997 .

Abstract 2278: The SMAC-mimetic birinapant regulates autocrine TNF production by caspase-8:RIPK1 complex via p38MAPK pathway

G. Kapoor, Y. Mitsuuchi, J. Silke, 2014 .

Increase of beta(III)- and beta(IVa)-tubulin isotopes in human prostate carcinoma cells as a result of estramustine resistance.

K. Tew, G. Hudes, C. Benetatos, 1996, Cancer research.

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

David L. Vaux, Vinay Tergaonkar, Pascal Schneider, 2007, Cell.

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.

Vinay Tergaonkar, Pascal Schneider, D. Vaux, 2007, Cell.

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Maryam Rashidi, Warren S. Alexander, Seth L. Masters, 2015, Nature Communications.

Sensitization of human bladder tumor cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis with a small molecule IAP antagonist

T. Griffith, M. O'Donnell, T. Kucaba, 2010, Apoptosis.

Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways

J. Hildebrand, J. Silke, S. Condon, 2017, Cell Death and Differentiation.

Birinapant (TL32711), a Bivalent SMAC Mimetic, Targets TRAF2-Associated cIAPs, Abrogates TNF-Induced NF-κB Activation, and Is Active in Patient-Derived Xenograft Models

Yigong Shi, G. Kapoor, Y. Mitsuuchi, 2014, Molecular Cancer Therapeutics.

The Novel SMAC Mimetic Birinapant Exhibits Potent Activity against Human Melanoma Cells

H. Pehamberger, M. Herlyn, K. Nathanson, 2013, Clinical Cancer Research.

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

D. Vaux, P. Schneider, J. Silke, 2008, The Journal of cell biology.

Abstract A25: Phase 1 PK/PD analysis of the Smac-mimetic TL32711 demonstrates potent and sustained cIAP1 suppression in patient PBMCs and tumor biopsies.

A. Tolcher, P. LoRusso, K. Papadopoulos, 2011 .

Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways

J. Hildebrand, J. Silke, S. Condon, 2017, Cell Death & Differentiation.

The discovery and structure-activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase.

T. Herbertz, D. Young, S. Condon, 2010, Bioorganic & medicinal chemistry letters.

The Discovery of Pyrano[3,4‐b]indole‐Based Allosteric Inhibitors of HCV NS5B Polymerase with In Vivo Activity

N. Kneteman, A. Howe, J. O'Connell, 2008, ChemMedChem.

Newly Synthesized Hepatitis C Virus Replicon RNA Is Protected from Nuclease Activity by a Protease-Sensitive Factor(s)

R. Jordan, M. Collett, D. Young, 2004, Journal of Virology.

The discovery and structure-activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase.

A. Gopalsamy, T. Herbertz, D. Young, 2010, Bioorganic & Medicinal Chemistry Letters.

Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2

T. Tenev, J. Silke, P. Meier, 2011, Cell Death and Differentiation.

The Novel SMAC Mimetic Birinapant Exhibits Potent Activity against Human Melanoma Cells

H. Pehamberger, M. Herlyn, K. Nathanson, 2013, Clinical Cancer Research.

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

D. Vaux, P. Schneider, J. Silke, 2008, The Journal of cell biology.