G. De Nucci

发表

VASORELAXING EFFECTS OF PROPRANOLOL IN RAT AORTA AND MESENTERIC ARTERY: A ROLE FOR NITRIC OXIDE AND CALCIUM ENTRY BLOCKADE

Haroldo A Toque, F. Priviero, C. Teixeira, 2006, Clinical and experimental pharmacology & physiology.

Comparative bioavailability of two suspension formulations of potassium diclofenac in healthy male volunteers.

G. De Nucci, G. Mendes, L. M. Franco, 1994, International journal of clinical pharmacology and therapeutics.

Prediction and biochemical characterization of intrinsic disorder in the structure of proteolysis-inducing factor/dermcidin.

J. Belizário, G. De Nucci, G. Majczak, 2007, Genetics and molecular research : GMR.

Relaxation of rabbit corpus cavernosum by selective activators of voltage-gated sodium channels: role of nitric oxide-cyclic guanosine monophosphate pathway.

C. Teixeira, G. De Nucci, E. Antunes, 2003, Urology.

Role of a novel tetrodotoxin-resistant sodium channel in the nitrergic relaxation of corpus cavernosum from the South American rattlesnake Crotalus durissus terrificus.

G. De Nucci, E. Antunes, M. Muscará, 2011, The journal of sexual medicine.

Sequence and structure‐activity relationship of a scorpion venom toxin with nitrergic activity in rabbit corpus cavernosum

G. Caliendo, V. Santagada, D. Ifa, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Crotoxin induces aggregation of human washed platelets.

S. Marangoni, J. Novello, B. Oliveira, 1994, Toxicon : official journal of the International Society on Toxinology.

Prostaglandin biosynthesis in the microcirculation: regulation by endothelial and non-endothelial factors.

G. De Nucci, S. Hyslop, 1993, Prostaglandins, leukotrienes, and essential fatty acids.

Superoxide dismutase isoforms 1 and 2 in lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin treatment.

G. De Nucci, M. Muscará, Rafaël De Sa, 2005, Brain research. Developmental brain research.

Comparative relaxing effects of sildenafil, vardenafil, and tadalafil in human corpus cavernosum: contribution of endogenous nitric oxide release.

F. Priviero, C. Teixeira, M. Claudino, 2009, Urology.

Vardenafil, but not sildenafil or tadalafil, has calcium‐channel blocking activity in rabbit isolated pulmonary artery and human washed platelets

C. Teixeira, G. De Nucci, E. Antunes, 2008, British journal of pharmacology.

Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide.

F. Priviero, C. Teixeira, M. Claudino, 2006, European journal of pharmacology.

6-Nitrodopamine is released by human umbilical cord vessels and modulates vascular reactivity.

G. De Nucci, E. Antunes, F. Mónica, 2021, Life sciences.

Activation of soluble guanylyl cyclase by BAY 58-2667 improves bladder function in cyclophosphamide-induced cystitis in mice.

G. De Nucci, E. Antunes, F. Mónica, 2016, American journal of physiology. Renal physiology.

Endothelium modulates electrical field stimulation-induced contractions of Chelonoidis carbonaria aortic rings.

G. De Nucci, E. Antunes, A. Justo, 2020, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin‐induced diabetic mice: evidence of a role for L‐type voltage‐operated Ca2+ channels

M. Claudino, G. De Nucci, C. Franco‐Penteado, 2011, British journal of pharmacology.

Characterization of the urinary bladder dysfunction in renovascular hypertensive rats

G. De Nucci, E. Antunes, C. Franco‐Penteado, 2011, Neurourology and urodynamics.

Fluconazole bioequivalence study: quantification by tandem mass spectrometry.

G. Corso, G. De Nucci, M. Moraes, 1999, Therapeutic drug monitoring.

The role of histamine in human penile erection.

R. Lopes-Martins, G. De Nucci, E. Antunes, 1995, British journal of urology.

Quantification of betamethasone in human plasma by liquid chromatography-tandem mass spectrometry using atmospheric pressure photoionization in negative mode.

G. De Nucci, A. Pereira, G. Mendes, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

The Evolutionary Implications of Hemipenial Morphology of Rattlesnake Crotalus durissus terrificus (Laurent, 1768) (Serpentes: Viperidae: Crotalinae)

K. Metze, G. De Nucci, E. Antunes, 2013, PloS one.

Mirabegron elicits rat corpus cavernosum relaxation and increases in vivo erectile response.

G. De Nucci, E. Antunes, F. Mónica, 2019, European journal of pharmacology.

In Silico Mapping of Essential Residues in the Catalytic Domain of PDE5 Responsible for Stabilization of Its Commercial Inhibitors

C. H. Lescano, G. De Nucci, Ivan Pires de Oliveira, 2019, Scientia Pharmaceutica.

Pre-exposure to Staphylococcal enterotoxin A exacerbates the pulmonary allergic eosinophil recruitment in rats.

G. De Nucci, E. Antunes, E. Camargo, 2010, International immunopharmacology.

Quantification of carvedilol in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry: application to bioequivalence study.

G. De Nucci, G. Mendes, N. C. do Carmo Borges, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

QSAR models for inhibitors of physiological impact of Escherichia coli that leads to diarrhea.

G. Gini, E. Benfenati, J. Leszczynski, 2013, Biochemical and biophysical research communications.

Inhibitory effects on human eosinophil chemotaxis in vitro by BAY 41-2272, an activator of nitric oxide-independent site of soluble guanylate cyclase.

G. De Nucci, E. Antunes, S. M. Thomazzi, 2005, Biochemical pharmacology.

Attenuation of Hypertension, Cardiomyocyte Hypertrophy, and Myocardial Fibrosis by &bgr;-Adrenoceptor Blockers in Rats Under Long-term Blockade of Nitric Oxide Synthesis

G. De Nucci, E. Antunes, I. M. D. De Luca, 2002, Journal of cardiovascular pharmacology.

Urinary Bladder Dysfunction in Transgenic Sickle Cell Disease Mice

F. Costa, M. Claudino, G. De Nucci, 2015, PloS one.

Human neutrophil migration in vitro induced by secretory phospholipases A2: a role for cell surface glycosaminoglycans.

A. Gambero, H. Nader, S. Marangoni, 2002, Biochemical pharmacology.

Development Of An Experimental Model Of Liver Cirrhosis In Rabbits

G. De Nucci, J. Pedrazzoli, J.G.P. Ferraz, 2000, Clinical and experimental pharmacology & physiology.

Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP.

S. Mccann, J. Antunes-Rodrigues, E. Cárnio, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Mycophenolate Mofetil Reduces Renal Injury in the Chronic Nitric Oxide Synthase Inhibition Model

R. Zatz, D. Malheiros, G. De Nucci, 2001, Hypertension.

Pharmacological characterisation of the relaxation induced by the soluble guanylate cyclase activator, BAY 60‐2770 in rabbit corpus cavernosum

G. De Nucci, E. Antunes, F. Mónica, 2015, BJU international.

Reactivity of mesenteric and aortic rings from trained rats fed with high caloric diet.

G. De Nucci, A. Zanesco, E. Antunes, 2007, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Electrical field stimulation-induced contractions on Pantherophis guttatus corpora cavernosa and aortae

G. De Nucci, E. Antunes, A. Justo, 2018, PloS one.

Quantification of chlordesmethyldiazepam by liquid chromatography-tandem mass spectrometry: application to a cloxazolam bioequivalence study.

G. De Nucci, G. Mendes, R. Barrientos-Astigarraga, 2009, Biomedical chromatography : BMC.

The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion.

F. Murad, S. Lilla, G. De Nucci, 2010, European journal of pharmacology.

Endothelin has potent ulcerogenic and vasoconstrictor actions in the stomach.

J. Wallace, W. MacNaughton, G. Cirino, 1989, The American journal of physiology.

Prostaglandin E2 regulates inducible nitric oxide synthase in the murine macrophage cell line J774.

G. De Nucci, E. Cillari, S. Milano, 1995, Prostaglandins.

Improvement in relaxation response in corpus cavernosum from trained rats.

F. Priviero, C. Teixeira, M. Claudino, 2004, Urology.

Nitric oxide modulates eosinophil infiltration in antigen-induced airway inflammation in rats.

E. Bevilacqua, C. Teixeira, G. De Nucci, 1998, European journal of pharmacology.

Role of nitric oxide on in vitro human eosinophil migration.

G. De Nucci, E. Antunes, S. M. Thomazzi, 2001, Biochemical pharmacology.

Role of Ca2+ in vascular smooth muscle contractions induced by Phoneutria nigriventer spider venom.

C. Teixeira, G. De Nucci, E. Antunes, 2004, Toxicon : official journal of the International Society on Toxinology.

Role of adenosine triphosphate-dependent potassium channels in canine penile erection.

G. De Nucci, E. Antunes, A. Fregonesi, 2004, Urology.

Nitric oxide has a role in regulating VLA-4-integrin expression on the human neutrophil cell surface.

A. Gambero, G. De Nucci, E. Antunes, 2003, Biochemical pharmacology.

Nitric oxide regulates human eosinophil adhesion mechanisms in vitro by changing integrin expression and activity on the eosinophil cell surface

G. De Nucci, E. Antunes, I. Lorand-Metze, 2001, British journal of pharmacology.

Modulation of eosinophil migration from bone marrow to lungs of allergic rats by nitric oxide.

G. De Nucci, E. Antunes, I. M. D. De Luca, 2004, Biochemical pharmacology.

Activation by Phoneutria nigriventer spider venom of autonomic nerve fibers in the isolated rat heart.

G. De Nucci, A. Zanesco, E. Antunes, 1998, European journal of pharmacology.

Influence of physical preconditioning on the responsiveness of rat pulmonary artery after pulmonary ischemia/reperfusion.

G. De Nucci, A. Zanesco, E. Antunes, 2007, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Amiloride Relaxes Rat Corpus Cavernosum Relaxation In Vitro and Increases Intracavernous Pressure In Vivo.

M. Claudino, G. De Nucci, E. Antunes, 2019, The journal of sexual medicine.

Effect of therapy with recombinant human interferon-gamma on the release of nitric oxide by neutrophils and mononuclear cells from patients with chronic granulomatous disease.

G. De Nucci, M. Muscará, A. Condino-Neto, 1996, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Quantification of isosorbide 5-mononitrate in human plasma by liquid chromatography-tandem mass spectrometry using atmospheric pressure photoionization.

G. De Nucci, A. Pereira, G. Mendes, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Human eosinophil adhesion and degranulation stimulated with eotaxin and RANTES in vitro: Lack of interaction with nitric oxide

G. De Nucci, A. Zanesco, E. Antunes, 2008, BMC pulmonary medicine.

Enalapril does not prevent the myocardial ischemia caused by the chronic inhibition of nitric oxide synthesis.

K. Metze, R. Zatz, G. De Nucci, 1995, European journal of pharmacology.

Simultaneous quantification of GMP, AMP, cyclic GMP and cyclic AMP by liquid chromatography coupled to tandem mass spectrometry.

J. Donato, S. Lilla, G. De Nucci, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

6-NitroDopamine is an endogenous modulator of rat heart chronotropism.

G. De Nucci, E. Antunes, F. Mónica, 2022, Life sciences.

The Fate of Radioiodinated Endothelin‐1 and Endothelin‐3 in the Rat

J. Vane, E. Änggård, G. De Nucci, 1989, Journal of cardiovascular pharmacology.

Different mechanisms underlie the effects of acute and long-term inhibition of nitric oxide synthases in antigen-induced pulmonary eosinophil recruitment in BALB/C mice.

G. De Nucci, E. Antunes, S. Jancar, 2009, Pulmonary pharmacology & therapeutics.

Mechanisms of relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in rat tracheal smooth muscle.

G. De Nucci, E. Antunes, F. Mónica, 2010, European journal of pharmacology.

Enhanced Analgesic Effects and Gastrointestinal Safety of a Novel, Hydrogen Sulfide-Releasing Anti-Inflammatory Drug (ATB-352): A Role for Endogenous Cannabinoids

J. Wallace, A. Buret, C. Fowler, 2020, Antioxidants & redox signaling.

Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat.

K. Metze, R. Zatz, G. De Nucci, 1999, European journal of pharmacology.

Dissociation between the increase in systemic vascular resistance induced by acute nitric oxide synthesis inhibition and the decrease in cardiac output in anesthetized dogs.

G. De Nucci, H. Moreno Júnior, E. Antunes, 1997, Journal of cardiovascular pharmacology.

Cholinergic regulation along the pulmonary arterial tree of the South American rattlesnake: vascular reactivity, muscarinic receptors, and vagal innervation.

E. Taylor, Tobias Wang, G. De Nucci, 2020, American journal of physiology. Regulatory, integrative and comparative physiology.

Vasoactive mediators released by endothelins.

G. De Nucci, S. Hyslop, 1992, Pharmacological research.

The release of nitric oxide and superoxide anion by neutrophils and mononuclear cells from patients with sickle cell anaemia

F. Costa, V. Arruda, G. De Nucci, 1996, British journal of haematology.

Role of sensory innervation in the rat pulmonary neutrophil recruitment induced by staphylococcal enterotoxins type A and B.

G. De Nucci, E. Antunes, E. Camargo, 2009, European journal of pharmacology.

Mechanisms Involved in the Enhancement of Allergic Airways Neutrophil Influx by Permanent C-Fiber Degeneration in Rats

G. De Nucci, E. Antunes, M. Muscará, 2005, Journal of Pharmacology and Experimental Therapeutics.

Theophylline therapy inhibits neutrophil and mononuclear cell chemotaxis from chronic asthmatic children.

J. Ribeiro, A. Guglielmi, G. De Nucci, 1991, British journal of clinical pharmacology.

Contribution of C-fibers to leucocyte recruitment in bronchoalveolar lavage fluid and pleural cavity in the rat.

G. De Nucci, E. Antunes, S. Hyslop, 2001, European journal of pharmacology.

Microsoft Word-80063204-file00.docx

G. De Nucci, E. Antunes, Camila B. Mendes-Silvério, 2014 .

Metal-organic framework (MOF) nanomedicine preparations of sildenafil designed for the future treatment of pulmonary arterial hypertension

J. Mitchell, P. D. Lickiss, I. Marei, 2019, bioRxiv.

The basal release of endothelium-derived catecholamines regulates the contractions of Chelonoidis carbonaria aorta caused by electrical-field stimulation

G. De Nucci, E. Antunes, R. Moreno, 2020, Biology Open.

The release of lyso-PAF from guinea-pig lungs.

S. Moncada, L. Parente, G. De Nucci, 1985, European journal of pharmacology.

The synthesis of eicosanoids induced by anaphylaxis in guinea-pig isolated lungs perfused via the trachea.

J. Salmon, S. Moncada, G. De Nucci, 1986, European journal of pharmacology.

EFFECT OF BAY 41‐2272 IN THE PULMONARY HYPERTENSION INDUCED BY HEPARIN–PROTAMINE COMPLEX IN ANAESTHETIZED DOGS

J. Annichino-Bizzacchi, G. De Nucci, E. Antunes, 2007, Clinical and experimental pharmacology & physiology.

Role of Endothelin-1 and Thromboxane A2 in the Pulmonary Hypertension Induced by Heparin–Protamine Interaction in Anesthetized Dogs

D. Dragosavac, G. De Nucci, E. Antunes, 2004, Journal of cardiovascular pharmacology.

Cyclooxygenase selectivity of non-steroid anti-inflammatory drugs in humans: ex vivo evaluation.

T. Warner, G. De Nucci, F. Giuliano, 2001, European journal of pharmacology.

Involvement of nitric oxide in the smooth muscle tone of the isolated canine spleen and the responses to acetylcholine and substance P.

G. De Nucci, E. Antunes, D. Grassi-Kassisse, 1996, Journal of autonomic pharmacology.

Activation of tissue kallikrein-kininogen-kinin system in rabbit skin by a fraction isolated from Phoneutria nigriventer (armed spider) venom.

J. Giglio, G. De Nucci, E. Antunes, 1993, Toxicon : official journal of the International Society on Toxinology.

Expression and activity of nitric oxide synthase isoforms in rat brain during the development of experimental allergic encephalomyelitis.

P. Arruda, L. M. Santos, F. Papes, 2002, Brain research. Molecular brain research.

Acute pulmonary inflammation induced by exposure of the airways to staphylococcal enterotoxin type B in rats.

G. De Nucci, E. Antunes, M. Muscará, 2006, Toxicology and applied pharmacology.

Inflammatory mechanisms underlying the rat pulmonary neutrophil influx induced by airway exposure to staphylococcal enterotoxin type A

G. De Nucci, E. Antunes, M. Muscará, 2005, British journal of pharmacology.

Endothelin‐1 and Endothelin‐3 Release EDRF from Isolated Perfused Arterial Vessels of the Rat and Rabbit

J. Vane, J. Mitchell, T. Warner, 1989, Journal of Cardiovascular Pharmacology.

Pharmacological characterization of kinin-induced relaxation of human corpus cavernosum.

C. Teixeira, G. De Nucci, E. Antunes, 1998, British journal of urology.

Release of vasoactive substances from guinea pig isolated lungs perfused via the trachea.

S. Moncada, G. De Nucci, 1987, The American review of respiratory disease.

Small-dose inhaled nitric oxide attenuates hemodynamic changes after pulmonary air embolism in dogs.

J. Tanus-Santos, G. De Nucci, H. Moreno, 1999, Anesthesia and analgesia.

The soluble guanylyl cyclase activator BAY 60-2770 inhibits murine allergic airways inflammation and human eosinophil chemotaxis.

G. De Nucci, E. Antunes, A. Condino-Neto, 2016, Pulmonary pharmacology & therapeutics.

Expression of nitric oxide synthases and in vitro migration of eosinophils from allergic rhinitis subjects.

L. Kandratavicius, G. De Nucci, E. Antunes, 2002, European journal of pharmacology.

Role of kinins and nitric oxide on the rabbit arthritis induced by Bothrops jararaca venom.

S. Farsky, G. De Nucci, E. Antunes, 2000, Toxicon : official journal of the International Society on Toxinology.

Mechanism of pain induced by radiocontrast media.

G. De Nucci, E. Antunes, A. Corrado, 1992, Toxicology letters.

Hydrochlorothiazide Potentiates Contractile Activity of Mouse Cavernosal Smooth Muscle

Mauro Napolitano, M. Claudino, G. De Nucci, 2016, Sexual medicine.

Effect of chronic nitric oxide synthesis inhibition on the inflammatory responses induced by carrageenin in rats.

R. Zatz, G. De Nucci, E. Antunes, 1995, European journal of pharmacology.

Inhaled nitric oxide improves hemodynamics during a venous air infusion (VAI) in dogs

J. Tanus-Santos, G. De Nucci, R. Moreno, 1999, Intensive Care Medicine.

Involvement of nitric oxide on the peritoneal neutrophil influx induced by staphylococcal enterotoxin B in mouse.

G. De Nucci, E. Antunes, S. Teixeira, 2001, Toxicon : official journal of the International Society on Toxinology.

Inhibition of human platelet aggregation by eosinophils.

S. Lilla, G. De Nucci, J. Donato, 2013, Life sciences.

Immunohistochemical and functional characterization of nitric oxide signaling pathway in isolated aorta from Crotalus durissus terrificus.

G. De Nucci, E. Antunes, F. Mónica, 2012, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

Endothelin-1 contracts isolated vessels independently of dihydropyridine-sensitive Ca2+ channel activation.

J. Vane, G. De Nucci, P. D'Orléans-Juste, 1989, European journal of pharmacology.

Pharmacology of Endothelin‐1 in Isolated Vessels: Effect of Nicardipine, Methylene Blue, Hemoglobin, and Gossypol

J. Vane, G. De Nucci, P. D'Orléans-Juste, 1989, Journal of cardiovascular pharmacology.

Superoxide Dismutase Cooperates with Prostacyclin to Inhibit Platelet Aggregation: a Comparative Study in Washed Platelets and Platelet Rich Plasma

J. Vane, G. De Nucci, D. Salvemini, 1991, Thrombosis and Haemostasis.

Comparison of the Effect of Endothelin on Microvessels and Macrovessels in Goldblatt II and Deoxycorticosterone Acetate‐Salt Hypertensive Rats

Z. Fortes, G. De Nucci, D. Nigro, 1990, Hypertension.

Endothelin‐1 Releases Eicosanoids from Rabbit Isolated Perfused Kidney and Spleen

J. Vane, G. De Nucci, G. Rae, 1989, Journal of cardiovascular pharmacology.

Structural and biological characterization of a crotapotin isoform isolated from Crotalus durissus cascavella venom.

S. Marangoni, M. Toyama, A. Havt, 2003, Toxicon : official journal of the International Society on Toxinology.

Signalling pathways regulating human neutrophil migration induced by secretory phospholipases A2.

A. Gambero, A. Cintra, G. De Nucci, 2004, Toxicon : official journal of the International Society on Toxinology.

Characterisation of functional endothelin receptors in the canine isolated perfused spleen.

R. Zatz, G. De Nucci, D. Grassi-Kassisse, 1995, European journal of pharmacology.

Comparative Bioavailability Study with Two Gemfibrozil Tablet Formulations in Healthy Volunteers

G. De Nucci, G. Mendes, G. Nucci, 2005, Arzneimittelforschung.

Influence of Liposomal Local Anesthetics on Platelet Aggregation In Vitro

M. H. Santana, G. De Nucci, E. de Paula, 2004, Journal of liposome research.

Analysis of five streptokinase formulations using the euglobulin lysis test and the plasminogen activation assay.

J. Donato, G. De Nucci, L. T. Couto, 2004, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Pharmacokinetics of Riluzole in Beagle Dogs

A. Perdigão, R. D. da Costa, G. De Nucci, 2018, Drug Research.

Effect of crotapotin and heparin on the rat paw oedema induced by different secretory phospholipases A2.

S. Marangoni, M. Toyama, G. Cirino, 2000, Toxicon : official journal of the International Society on Toxinology.

Neutrophils and mononuclear cells from patients with chronic granulomatous disease release nitric oxide.

G. De Nucci, M. Muscará, A. Condino-Neto, 1993, British journal of clinical pharmacology.

Anaphylaxis in guinea pigs induced by ovalbumin aerosol in vivo and in vitro methods.

G. De Nucci, A. Payne, 1987, Journal of pharmacological methods.

Inflammatory oedema induced by phospholipases A2 isolated from Crotalus durissus sp. in the rat dorsal skin: a role for mast cells and sensory C-fibers.

S. Marangoni, M. Toyama, G. De Nucci, 2003, Toxicon : official journal of the International Society on Toxinology.

A proof‐of‐concept, Phase 2 clinical trial of the gastrointestinal safety of a hydrogen sulfide‐releasing anti‐inflammatory drug

J. Wallace, A. Buret, G. De Nucci, 2020, British journal of pharmacology.

Prolonged therapy with the soluble guanylyl cyclase activator BAY 60-2770 restores the erectile function in obese mice.

G. De Nucci, E. Antunes, A. Davel, 2014, The journal of sexual medicine.

Tetrodotoxin-insensitive electrical field stimulation-induced contractions on Crotalus durissus terrificus corpus cavernosum

G. De Nucci, E. Antunes, R. Moreno, 2017, PloS one.

Long-term nitric oxide inhibition and chronotropic responses in rat isolated right atria.

G. De Nucci, A. Zanesco, E. Antunes, 1999, Hypertension.

Dose-dependent beneficial hemodynamic effects of BAY 41-2272 in a canine model of acute pulmonary thromboembolism.

J. Tanus-Santos, G. De Nucci, E. Antunes, 2008, European journal of pharmacology.

Quantification of cyclic AMP and cyclic GMP levels in Krebs-Henseleit solution by LC-MS/MS: Application in washed platelet aggregation samples.

G. De Nucci, Weverton C. Coelho-Silva, Charles Elliot Serpellone Nash, 2022, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Platelets induce human umbilical vein endothelial cell proliferation through P-selectin.

G. De Nucci, F. Rendu, S. Marcondes, 2000, Life sciences.

Purification and initial characterization of a novel protein with factor Xa activity from Lonomia obliqua caterpillar spicules.

R. Pereira, J. Donato, S. Lilla, 2005, Journal of mass spectrometry : JMS.

Lonomia obliqua Caterpillar Spicules Trigger Human Blood Coagulation via Activation of Factor X and Prothrombin

J. Donato, B. L. Le Bonniec, G. De Nucci, 1998, Thrombosis and Haemostasis.

Endothelium‐derived dopamine modulates EFS‐induced contractions of human umbilical vessels

G. De Nucci, E. Antunes, A. Justo, 2020, Pharmacology research & perspectives.

Simultaneous determination of nitrite and nitrate anions in plasma, urine and cell culture supernatants by high-performance liquid chromatography with post-column reactions.

G. De Nucci, M. Muscará, 1996, Journal of chromatography. B, Biomedical applications.

Electrical field stimulation induces endothelium-dependent contraction of human umbilical cord vessels.

G. De Nucci, E. Antunes, R. Moreno, 2020, Life sciences.

Characterization of endothelin receptors in isolated, perfused human spleen.

G. De Nucci, I. Boin, E. Antunes, 1998, Journal of cardiovascular pharmacology.

Chronic nitric oxide synthase inhibition aggravates glomerular injury in rats with subtotal nephrectomy.

R. Zatz, G. De Nucci, C. Fujihara, 1995, Journal of the American Society of Nephrology : JASN.

Effects of acute nitric oxide inhibition on rat glomerular microcirculation.

R. Zatz, G. De Nucci, 1991, The American journal of physiology.

Atypical β-Adrenoceptor Subtypes Mediate Relaxations of Rabbit Corpus Cavernosum

C. Teixeira, G. De Nucci, A. Zanesco, 2004, Journal of Pharmacology and Experimental Therapeutics.

Inhibitory effects of staphylococcal enterotoxin type B on human platelet adhesion in vitro

S. Marangoni, P. Baldasso, G. De Nucci, 2008, Platelets.

Quantification of the bombesin/gastrin releasing peptide antagonist RC-3095 by liquid chromatography-tandem mass spectrometry.

S. Lilla, G. Schwartsmann, G. De Nucci, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled.

J. Vane, T. Warner, R. Gryglewski, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Bioequivalence study between a fixed-dose single-pill formulation of nebivolol plus hydrochlorothiazide and separate formulations in healthy subjects using high-performance liquid chromatography coupled to tandem mass spectrometry.

T. L. Laurito, G. De Nucci, R. Moreno, 2017, Biomedical chromatography : BMC.

Renal effects of acute and chronic nitric oxide inhibition in experimental diabetes.

R. Zatz, G. De Nucci, C. Fujihara, 1996, Nephron.

Ciprofibrate quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry for pharmacokinetic studies.

G. De Nucci, K. Alkharfy, G. Mendes, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

PHARMACOKINETICS AND PHARMACODYNAMICS OF A NITRIC OXIDE‐RELEASING DERIVATIVE OF ENALAPRIL IN MALE BEAGLES

G. De Nucci, E. Antunes, G. Mendes, 2007, Clinical and experimental pharmacology & physiology.

The relaxation of isolated rabbit corpus cavernosum by the herbal medicine Catuama® and its constituents

C. Teixeira, G. De Nucci, E. Antunes, 2001, Phytotherapy research : PTR.

Bioequivalence study of two enalapril maleate tablet formulations in healthy male volunteers Pharmacokinetic versus pharmacodynamic approach

G. De Nucci, G. Mendes, M. Muscará, 1996, European Journal of Clinical Pharmacology.

Protective effects of exogenous and endogenous hydrogen sulfide in mast cell‐mediated pruritus and cutaneous acute inflammation in mice

M. Whiteman, M. Wood, G. De Nucci, 2017, Pharmacological research.

Biochemical and enzymatic characterization of two basic Asp49 phospholipase A2 isoforms from Lachesis muta muta (Surucucu) venom.

F. V. Winck, S. Lilla, S. Marangoni, 2005, Biochimica et biophysica acta.

Inflammatory oedema induced by Lachesis muta muta (Surucucu) venom and LmTX-I in the rat paw and dorsal skin.

S. Marangoni, G. De Nucci, E. Antunes, 2009, Toxicon : official journal of the International Society on Toxinology.

Vascular effects of long-term propranolol administration after chronic nitric oxide blockade.

F. Priviero, C. Teixeira, M. Claudino, 2007, European journal of pharmacology.

In vitro metabolism of the new antifungal dapaconazole using liver microsomes.

L. Couchman, G. De Nucci, A. Pilon, 2022, Drug metabolism and pharmacokinetics.

Quantification of dapaconazole in human plasma using high-performance liquid chromatography coupled to tandem mass spectrometry: application to a phase I study.

E. Perissutti, G. De Nucci, A. Arruda, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Endothelin‐1 Participation in Overt and Inflammatory Pain

S. Ferreira, G. De Nucci, M. Romitelli, 1989, Journal of cardiovascular pharmacology.

Activation of Haem-Oxidized Soluble Guanylyl Cyclase with BAY 60-2770 in Human Platelets Lead to Overstimulation of the Cyclic GMP Signaling Pathway

G. De Nucci, E. Antunes, Camila B. Mendes-Silvério, 2012, PloS one.

MECHANISMS UNDERLYING RELAXATION OF RABBIT AORTA BY BAY 41‐2272, A NITRIC OXIDE‐INDEPENDENT SOLUBLE GUANYLATE CYCLASE ACTIVATOR

F. Priviero, C. Teixeira, M. Claudino, 2005, Clinical and experimental pharmacology & physiology.

Nitric oxide release from human corpus cavernosum induced by a purified scorpion toxin.

F. Priviero, C. Teixeira, G. De Nucci, 2004, Urology.

Anastrozole quantification in human plasma by high-performance liquid chromatography coupled to photospray tandem mass spectrometry applied to pharmacokinetic studies.

G. De Nucci, A. Pereira, G. Mendes, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Inhibition of heparin synthesis by methotrexate in rats in vivo.

H. Nader, C. Dietrich, G. De Nucci, 2002, Biochemical pharmacology.

Quantification of mycophenolic acid in human plasma by liquid chromatography with time-of-flight mass-spectrometry for therapeutic drug monitoring.

L. Couchman, D. Holt, G. De Nucci, 2020, Biomedical chromatography : BMC.

Laser Therapy and Muscle Fatigue: A Promising Research Area.

R. Lopes-Martins, G. De Nucci, Fernando Pazzelo Mafra, 2016, Photomedicine and laser surgery.

Effects of beta-adrenoceptor antagonists in the neural nitric oxide release induced by electrical field stimulation and sodium channel activators in the rabbit corpus cavernosum.

C. Teixeira, G. De Nucci, E. Antunes, 2005, European journal of pharmacology.

Amlodipine bioequivalence study: quantification by liquid chromatography coupled to tandem mass spectrometry

G. De Nucci, M. Moraes, G. Mendes, 2001, Biopharmaceutics & drug disposition.

Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum.

C. Teixeira, G. De Nucci, E. Antunes, 2008, European journal of pharmacology.

Long‐term oral treatment with BAY 41‐2272 ameliorates impaired corpus cavernosum relaxations in a nitric oxide‐deficient rat model

M. Claudino, G. De Nucci, E. Antunes, 2011, BJU international.

Vas deferens smooth muscle responses to the nitric oxide-independent soluble guanylate cyclase stimulator BAY 41-2272.

M. Claudino, G. De Nucci, E. Antunes, 2012, European journal of pharmacology.

Evaluation of the relaxant effect of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in isolated detrusor smooth muscle.

F. Priviero, G. De Nucci, E. Antunes, 2010, European journal of pharmacology.

Increased cyclic guanosine monophosphate synthesis and calcium entry blockade account for the relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in the rabbit penile urethra.

C. Teixeira, G. De Nucci, E. Antunes, 2008, Urology.

Relaxing effects induced by the soluble guanylyl cyclase stimulator BAY 41-2272 in human and rabbit corpus cavernosum.

F. Priviero, C. Teixeira, G. De Nucci, 2003, European journal of pharmacology.

Synthesis and pharmacological evaluations of sildenafil analogues for treatment of erectile dysfunction.

G. Caliendo, V. Santagada, E. Perissutti, 2008, Journal of medicinal chemistry.

Lisinopril quantification in human plasma by liquid chromatography-electrospray tandem mass spectrometry.

G. De Nucci, G. Mendes, R. Barrientos-Astigarraga, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor.

J. Vane, R. Gryglewski, G. De Nucci, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Comparison of dapaconazole with miconazole in the treatment of Tinea cruris

G. De Nucci, A. Gobbato, N. Antunes, 2018, Journal of the European Academy of Dermatology and Venereology : JEADV.

A randomized double-blind, non-inferiority Phase II trial, comparing dapaconazole tosylate 2% cream with ketoconazole 2% cream in the treatment of Pityriasis versicolor

G. De Nucci, A. Gobbato, T. Babadópulos, 2015, Expert opinion on investigational drugs.

The rabbit vagina as an in vivo model for vaginal fenticonazole permeability and toxicity.

G. De Nucci, R. Moreno, Marcovan Porto, 2018, Journal of pharmacological and toxicological methods.

Prospective Prediction of Dapaconazole Clinical Drug–Drug Interactions Using an In Vitro to In Vivo Extrapolation Equation and PBPK Modeling

L. Couchman, G. De Nucci, K. Kipper, 2022, Pharmaceuticals.

Eicosanoids and skin.

G. De Nucci, 1988, Biochemical Society transactions.

Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension.

R. Zatz, G. De Nucci, E. Antunes, 1992, Hypertension.

Effect of arginine analogues on rat hind paw oedema and mast cell activation in vitro.

G. Cirino, R. Zatz, G. De Nucci, 1994, European journal of pharmacology.

Terbinafine Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Tandem Mass Spectrometry: Application to a Bioequivalence Study

M. E. D. de Moraes, G. De Nucci, F. A. Bezerra, 2001, Therapeutic drug monitoring.

Dapaconazole versus ketoconazole in the treatment of interdigital tinea pedis.

G. De Nucci, R. Moreno, A. Gobbato, 2017, International journal of clinical pharmacology and therapeutics.

Comparative bioavailability of two fluconazole capsule formulations in healthy volunteers.

G. De Nucci, F. A. Bezerra, M. Moraes, 2011, Arzneimittel-Forschung.

Short-term sucralfate administration alters potassium diclofenac absorption in healthy male volunteers.

M. A. Pierossi, F D Mendes, G de Nucci, 1997, British journal of clinical pharmacology.

Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat.

J. Vane, T. Warner, G. De Nucci, 1989, European journal of pharmacology.

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

J. Vane, T. Warner, G. De Nucci, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Soluble Guanylyl Cyclase (sGC) Degradation and Impairment of Nitric Oxide-Mediated Responses in Urethra from Obese Mice: Reversal by the sGC Activator BAY 60-2770

G. De Nucci, E. Antunes, Camila B. Mendes-Silvério, 2014, The Journal of Pharmacology and Experimental Therapeutics.

A high-throughput method for determining chloramphenicol residues in poultry, egg, shrimp, fish, swine and bovine using LC-ESI-MS/MS.

G. De Nucci, F. Reyes, Silvia Regina Rocha Siqueira, 2009, Journal of separation science.

Lansoprazole quantification in human plasma by liquid chromatography-electrospray tandem mass spectrometry.

G. De Nucci, E. Abib, G. Mendes, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Single-dose pharmacokinetics and pharmacodynamics assessment of oestriol and trimegestone containing vaginal rings in healthy women with childbearing potential

G. De Nucci, R. Moreno, Natalícia de Jesus Antunes, 2021, The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception.

Determination of pantoprazole in human plasma by LC-MS-MS using lansoprazole as internal standard.

G. De Nucci, G. Mendes, R. Barrientos-Astigarraga, 2011, Arzneimittel-Forschung.

Plasma hydroxy-metronidazole/metronidazole ratio in patients with liver disease and in healthy volunteers.

G. De Nucci, M. Muscará, J. Ferraz, 1995, British journal of clinical pharmacology.

Modulation of coronary flow and cardiomyocyte size by sensory fibers.

G. De Nucci, A. Zanesco, E. Antunes, 1999, Hypertension.

Phoneutria nigriventer spider venom induces oedema in rat skin by activation of capsaicin sensitive sensory nerves.

G. De Nucci, E. Antunes, S. Brain, 1997, European journal of pharmacology.

Acute inhibition of nitric oxide synthesis induces anxiolysis in the plus maze test.

F. Graeff, G. De Nucci, M. Muscará, 1997, European journal of pharmacology.

Rebamipide does not protect against naproxen-induced gastric damage: a randomized double-blind controlled trial

J. Wallace, Mauro Napolitano, G. De Nucci, 2016, BMC Gastroenterology.

Nevirapine quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study.

G. Caliendo, V. Santagada, T. L. Laurito, 2002, Journal of mass spectrometry : JMS.

Simultaneous determination of dextromethorphan, dextrorphan and doxylamine in human plasma by HPLC coupled to electrospray ionization tandem mass spectrometry: application to a pharmacokinetic study.

J. Donato, G. De Nucci, A. S. Pereira, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantification of estradiol cypionate in plasma by liquid chromatography coupled with tandem mass spectrometry: Application in a pharmacokinetic study in healthy female volunteers

G. Caliendo, G. De Nucci, R. Moreno, 2019, Journal of Pharmaceutical and Biomedical Analysis.

Biochemical characterization of a vascular smooth muscle contracting polypeptide purified from Phoneutria nigriventer (armed spider) venom.

G. Domont, S. Marangoni, J. Giglio, 1993, Toxicon : official journal of the International Society on Toxinology.

Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration

G. Caliendo, V. Santagada, E. Perissutti, 2019, Frontiers in Pharmacology.

Atmospheric pressure photoionization applied to quantitation of cyproterone acetate in human plasma.

G. De Nucci, A. Pereira, G. Mendes, 2005, Journal of chromatographic science.

Leucocyte recruitment induced by type II phospholipases A(2) into the rat pleural cavity.

S. Marangoni, M. Toyama, J. Giglio, 2000, Toxicon : official journal of the International Society on Toxinology.

Mast cell degranulation induced by two phospholipase A2 homologues: dissociation between enzymatic and biological activities.

S. Marangoni, J. Giglio, A. Cintra, 1998, European journal of pharmacology.

Insulin relaxes bladder via PI3K/AKT/eNOS pathway activation in mucosa: unfolded protein response‐dependent insulin resistance as a cause of obesity‐associated overactive bladder

G. De Nucci, E. Antunes, F. Mónica, 2013, The Journal of physiology.

Pharmacological and transcriptomic characterization of the nitric oxide pathway in aortic rings isolated from the tortoise Chelonoidis carbonaria.

Mauro Napolitano, G. De Nucci, A. Justo, 2019, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

The beta‐3 adrenoceptor agonist, mirabegron relaxes isolated prostate from human and rabbit: New therapeutic indication?

G. De Nucci, E. Antunes, F. Mónica, 2015, The Prostate.

Release of eicosanoids from isolated lungs of guinea-pigs exposed to pure oxygen: effect of dexamtethasone.

J. Salmon, S. Moncada, G. De Nucci, 1986, European journal of pharmacology.

Upregulation of muscarinic receptors by long‐term nitric oxide inhibition in the rat ileum

C. Porto, G. De Nucci, A. Zanesco, 2003, Clinical and experimental pharmacology & physiology.

Endothelial progenitor cell mobilization and platelet microparticle release are influenced by clopidogrel plasma levels in stable coronary artery disease.

R. Salomão, M. Brunialti, F. Fonseca, 2012, Circulation journal : official journal of the Japanese Circulation Society.

Pharmacokinetic and Pharmacodynamic Evaluation of a Nanotechnological Topical Formulation of Lidocaine/Prilocaine (Nanorap) in Healthy Volunteers

Wanderley de Souza, G. De Nucci, A. Arruda, 2015, Therapeutic drug monitoring.

Gabapentin quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study.

D. Ifa, G. De Nucci, M. Moraes, 2001, Journal of mass spectrometry : JMS.

Role of Substance P and Bradykinin in Acute Pancreatitis Induced by Secretory Phospholipase A2

G. De Nucci, E. Antunes, M. Ribela, 2008, Pancreas.

Pharmacokinetics and pharmacodynamics of three dosages of oestriol after continuous vaginal ring administration for 21 days in healthy, postmenopausal women

G. De Nucci, R. Moreno, N. Antunes, 2018, British journal of clinical pharmacology.

Investigation of the haemodynamic effects of Phoneutria nigriventer venom in anaesthetised rabbits.

G. De Nucci, E. Antunes, E. Tibirica, 2000, Toxicon : official journal of the International Society on Toxinology.

Cyclic GMP-independent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: a role for alpha-actinin nitration.

F. Murad, S. Lilla, G. De Nucci, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Tadalafil for the treatment of benign prostatic hyperplasia

G. De Nucci, F. Mónica, 2019, Expert opinion on pharmacotherapy.

Mechanisms of albuminuria in the chronic nitric oxide inhibition model.

R. Zatz, G. De Nucci, A. Sesso, 2000, American journal of physiology. Renal physiology.

Plasma hydroxy metronidazole/metronidazole ratio in anti-HCV carriers with and without apparent liver disease.

G. De Nucci, M. Muscará, J. Ferraz, 1998, British journal of clinical pharmacology.

Effects of different protocol doses of low power gallium-aluminum-arsenate (Ga-Al-As) laser radiation (650 nm) on carrageenan induced rat paw ooedema.

R. Zângaro, R. Lopes-Martins, R. Albertini, 2004, Journal of photochemistry and photobiology. B, Biology.

Phoneutria nigriventer (armed spider) venom induces increased vascular permeability in rat and rabbit skin in vivo.

G. De Nucci, E. Antunes, S. Brain, 1992, Toxicon : official journal of the International Society on Toxinology.

6‐nitrodopamine is a major endogenous modulator of human vas deferens contractility

G. De Nucci, E. Antunes, F. Mónica, 2022, Andrology.

Investigation on the positive chronotropic action of 6-nitrodopamine in the rat isolated atria

G. De Nucci, E. Antunes, F. Mónica, 2023, Naunyn-Schmiedeberg's Archives of Pharmacology.

Effect of salt intake and inhibitor dose on arterial hypertension and renal injury induced by chronic nitric oxide blockade.

A. L. Sassaki, R. Zatz, D. Malheiros, 1996, Hypertension.

Expression of nitric oxide synthase isoforms and nitrotyrosine immunoreactivity by B‐cell non‐Hodgkin’s lymphomas and multiple myeloma

F. Murad, F. Soares, G. De Nucci, 2001, Histopathology.

Inhibition of eosinophil chemotaxis by chronic blockade of nitric oxide biosynthesis.

C. Flores, G. De Nucci, P. Sannomiya, 1996, European journal of pharmacology.

Nitroflurbiprofen, a new nonsteroidal anti-inflammatory, ameliorates structural injury in the remnant kidney.

R. Zatz, D. Malheiros, G. De Nucci, 1998, American journal of physiology. Renal physiology.

Inflammatory oedema induced by the lys-49 phospholipase A(2) homologue piratoxin-i in the rat and rabbit. Effect of polyanions and p-bromophenacyl bromide.

S. Marangoni, M. Toyama, J. Giglio, 2000, Biochemical pharmacology.

Gastric Tolerability and Prolonged Prostaglandin Inhibition in the Brain with a Nitric Oxide-Releasing Flurbiprofen Derivative, NCX-2216 [3-[4-(2-Fluoro-α-methyl-[1,1′-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester]

E. Ongini, J. Wallace, G. Cirino, 2004, Journal of Pharmacology and Experimental Therapeutics.

Verapamil quantification in human plasma by liquid chromatography coupled to tandem mass spectrometry. An application for bioequivalence study.

G. De Nucci, G. Mendes, R. Barrientos-Astigarraga, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Exercise training ameliorates the impairment of endothelial and nitrergic corpus cavernosum responses in diabetic rats.

F. Priviero, M. Claudino, G. De Nucci, 2011, Life sciences.

Determination of minocycline in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry: application to bioequivalence study.

D. Ifa, G. De Nucci, M. Moraes, 2001, Journal of Chromatography B: Biomedical Sciences and Applications.

Development of cardiomyocyte hypotrophy in rats under prolonged treatment with a low dose of a nitric oxide synthesis inhibitor.

G. De Nucci, E. Antunes, S. Teixeira, 2000, European journal of pharmacology.

The effect of Phoneutria nigriventer (armed spider) venom on arterial blood pressure of anaesthetised rats.

G. De Nucci, E. Antunes, S. Brain, 1996, European Journal of Pharmacology.

Upregulation of gp91phox subunit of NAD(P)H oxidase contributes to erectile dysfunction caused by long-term nitric oxide inhibition in rats: reversion by regular physical training.

F. Priviero, M. Claudino, G. De Nucci, 2010, Urology.

Ex vivo evidence for PGE2 and LTB4 involvement in cutaneous leishmaniasis: relation with infection status and cytokine production

G. De Nucci, E. Cillari, S. Milano, 1996, Parasitology.

β1- and β1/β2-adrenergic receptor antagonists block 6-nitrodopamine-induced contractions of the rat isolated epididymal vas deferens

G. De Nucci, E. Antunes, F. Mónica, 2022, Naunyn-Schmiedeberg's Archives of Pharmacology.

Role of PKC and CaV1.2 in Detrusor Overactivity in a Model of Obesity Associated with Insulin Resistance in Mice

Angelina Zanesco, Edson Antunes, G. De Nucci, 2012, PloS one.

Randomized, double‐blind, phase III clinical study of a novel nanotechnological topical anesthetic formulation containing lidocaine 25 mg/g and prilocaine 25 mg/g (nanorap) in skin phototypes I–III patients with ablative fractional CO2 laser treatment indication in the forehead

G. De Nucci, R. Moreno, A. Gobbato, 2019, Lasers in surgery and medicine.

Reduction of inflammation in rats by diazepam: tolerance development.

J. Palermo-neto, G. De Nucci, M. Muscará, 2003, Life sciences.

In vitro mutagenicity of anti-inflammatory parsalmide analogues PA7, PA10, and PA31 triggered by biotransformation into hydroxy derivatives.

G. Caliendo, V. Santagada, E. Perissutti, 2006, European journal of medicinal chemistry.

Bioequivalence evaluation of two roxithromycin formulations in healthy human volunteers by high performance liquid cromatography coupled to tandem mass spectrometry.

D. Ifa, G. De Nucci, A. Corrado, 1999, Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia.

Felodipine quantification in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry.

G. De Nucci, B. Schug, A. Pereira, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Studies on metal–organic framework (MOF) nanomedicine preparations of sildenafil for the future treatment of pulmonary arterial hypertension

J. Mitchell, P. D. Lickiss, I. Marei, 2021, Scientific Reports.

Phentolamine bioequivalence study.

G. De Nucci, M. Moraes, F. A. Frota Bezerra, 2004, International journal of clinical pharmacology and therapeutics.

Purification, sequencing and structural analysis of two acidic phospholipases A2 from the venom of Bothrops insularis (jararaca ilhoa).

S. Lilla, G. F. Souza, G. De Nucci, 2006, Biochimie.

Isolation and partial characterization of a polypeptide from Phoneutria nigriventer spider venom that relaxes rabbit corpus cavernosum in vitro.

R. Lopes-Martins, S. Marangoni, J. Giglio, 1996, Toxicon : official journal of the International Society on Toxinology.

Identification of a new vascular smooth muscle contracting polypeptide in Phoneutria nigriventer spider venom.

S. Marangoni, J. Giglio, J. Novello, 1993, Biochemical Pharmacology.

Phoneutria nigriventer spider venom activates 5‐HT4 receptors in rat‐isolated vagus nerve

G. De Nucci, E. Antunes, S. Brain, 2003, British journal of pharmacology.

Nonadrenergic, noncholinergic relaxation of human isolated corpus cavernosum induced by scorpion venom.

C. Teixeira, G. De Nucci, E. Antunes, 2001, Urology.

The role of nitric oxide on the relaxations of rabbit corpus cavernosum induced by Androctonus australis and Buthotus judaicus scorpion venoms.

C. Teixeira, G. De Nucci, E. Antunes, 2001, Toxicon : official journal of the International Society on Toxinology.

Effect of Tityus serrulatus scorpion venom on the rabbit isolated corpus cavernosum and the involvement of NANC nitrergic nerve fibres

R. Lopes-Martins, J. Giglio, C. Teixeira, 1998, British journal of pharmacology.

Pharmacological characterization of the presynaptic activity of Tityus serrulatus venom in the rat anococcygeus muscle.

F. Priviero, C. Teixeira, G. De Nucci, 2003, Toxicon : official journal of the International Society on Toxinology.

Hydrogen Sulfide-Releasing Therapeutics: Translation to the Clinic.

J. Wallace, W. MacNaughton, G. De Nucci, 2017, Antioxidants & redox signaling.

Involvement of vanilloid receptors and purinoceptors in the Phoneutria nigriventer spider venom-induced plasma extravasation in rat skin.

G. De Nucci, E. Antunes, S. Brain, 2000, European journal of pharmacology.

Quantification of cyproheptadine in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry in a bioequivalence study.

G. De Nucci, K. Alkharfy, A. Arruda, 2012, Biomedical chromatography : BMC.

6-Nitrodopamine is an endogenous mediator of rat isolated epididymal vas deferens contractions induced by electric-field stimulation.

G. De Nucci, E. Antunes, F. Mónica, 2021, European journal of pharmacology.

6-Nitrodopamine potentiates contractions of rat isolated vas deferens induced by noradrenaline, adrenaline, dopamine and electric field stimulation

G. De Nucci, E. Antunes, A. Pupo, 2023, Naunyn-Schmiedeberg's Archives of Pharmacology.

Release of 6-nitrodopamine modulates vascular reactivity of Pantherophis guttatus aortic rings.

G. De Nucci, E. Antunes, A. Schenka, 2022, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

6-Nitrodopamine is an endogenous selective dopamine receptor antagonist in Chelonoidis carbonaria aorta.

G. De Nucci, R. Moreno, F. Mónica, 2022, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

Quantification of 6-nitrodopamine in Krebs-Henseleit's solution by LC-MS/MS for the assessment of its basal release from Chelonoidis carbonaria aortae in vitro.

R. Lopes-Martins, G. De Nucci, M. Moraes, 2021, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Electrical field-induced contractions on Crotalus durissus terrificus and Bothrops jararaca aortae are caused by endothelium-derived catecholamine

G. De Nucci, A. Justo, R. Moreno, 2018, PLoS ONE.

Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol

G. Caliendo, V. Santagada, E. Perissutti, 2022, Molecules.

Determination of dopamine, noradrenaline and adrenaline in Krebs-Henseleit's solution by liquid chromatography coupled tandem mass spectrometry. Measurement of basal release from Chelonoidis carbonaria aortae in vitro.

G. De Nucci, M. Moraes, M. Moraes, 2020, Biomedical chromatography : BMC.

Bromazepam determination in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry: a highly sensitive and specific tool for bioequivalence studies.

G. Caliendo, V. Santagada, M. E. D. de Moraes, 2004, Journal of mass spectrometry : JMS.

Implications of the use of semicarbazide as a metabolic target of nitrofurazone contamination in coated products

J. Donato, G. De Nucci, A. S. Pereira, 2004, Food additives and contaminants.

Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils.

F. Murad, G. De Nucci, E. Antunes, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The soluble guanylyl cyclase activator BAY 60-2770 ameliorates overactive bladder in obese mice.

G. De Nucci, E. Antunes, A. Davel, 2014, The Journal of urology.

Soluble Guanylate Cyclase Modulators, BAY 41-2272 and BAY 60-2770, Inhibit Human and Rabbit Prostate Contractility.

G. De Nucci, E. Antunes, F. Mónica, 2016, Urology.

Long‐term administration of BAY 41‐2272 prevents bladder dysfunction in nitric oxide‐deficient rats

G. De Nucci, E. Antunes, F. Mónica, 2011, Neurourology and urodynamics.

Comparative bioavailability of two zolpidem hemitartrate formulations in healthy human Brazilian volunteers using high-performance liquid chromatography coupled to tandem mass spectrometry.

R. Lopes-Martins, G. De Nucci, R. Moreno, 2020, Biomedical chromatography : BMC.

BAY 41-2272, a soluble guanylate cyclase stimulator, relaxes isolated human ureter in a standardized in vitro model.

M. Monga, G. De Nucci, E. Antunes, 2014, Urology.

Renal expression of COX-2, ANG II, and AT1 receptor in remnant kidney: strong renoprotection by therapy with losartan and a nonsteroidal anti-inflammatory.

I. L. Noronha, R. Zatz, D. Malheiros, 2004, American journal of physiology. Renal physiology.

Clonazepam quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study.

T. Monif, G. De Nucci, S. Reyar, 2007, Journal of mass spectrometry : JMS.

Determination of nitrofuran metabolites in poultry muscle and eggs by liquid chromatography-tandem mass spectrometry.

G. De Nucci, J. Donato, M. Sucupira, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Comparison of two marketed nifedipine modified-release formulations: an exploratory clinical food interaction study.

E. Brendel, G. De Nucci, B. Schug, 2008, Clinical Therapeutics.

Comparative bioavailability of two atenolol tablet formulations in healthy male volunteers after a single dose administration.

M. A. Pierossi, G. De Nucci, G. Mendes, 1997, International journal of clinical pharmacology and therapeutics.

Assessment of pharmacokinetic interaction between piracetam and l-carnitine in healthy subjects.

J. Ramacciato, G. De Nucci, R. Motta, 2016, Biomedical chromatography : BMC.

The importance of the endothelial nitric oxide synthase on the release of 6-nitrodopamine from mouse isolated atria and ventricles and their role on chronotropism.

G. De Nucci, E. Antunes, F. Mónica, 2023, Nitric oxide : biology and chemistry.

Release of 6-nitrodopamine from human popliteal artery and vein.

G. De Nucci, F. Mónica, A. Schenka, 2023, Life sciences.

Evidence for the existence of two distinct functions for the inducible NO synthase in the rat kidney: effect of aminoguanidine in rats with 5/6 ablation.

J. Vieira, R. Zatz, D. Malheiros, 2002, Journal of the American Society of Nephrology : JASN.

The mechanisms and significance of the coupled release of endothelium-derived relaxing factor (EDRF) and prostacyclin (PGI2) from endothelial cells.

G. De Nucci, S. Hyslop, 1991, Wiener klinische Wochenschrift.

Determination of 21-hydroxydeflazacort in human plasma by high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. Application to bioequivalence study.

G. Caliendo, D. Ifa, G. De Nucci, 2000, Journal of mass spectrometry : JMS.

Sodium excess aggravates hypertension and renal parenchymal injury in rats with chronic NO inhibition.

R. Zatz, G. De Nucci, C. Fujihara, 1994, The American journal of physiology.

Tolerability of 2.5% Lidocaine/Prilocaine Hydrogel in Children Undergoing Cryotherapy for Molluscum Contagiosum

G. De Nucci, R. Moreno, A. Gobbato, 2016, Pediatric dermatology.

Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage.

J. Wallace, G. Caliendo, V. Santagada, 2001, European journal of medicinal chemistry.

Nifedipine prevents renal injury in rats with chronic nitric oxide inhibition.

R. Zatz, G. De Nucci, E. Antunes, 1995, Hypertension.

Comparative bioavailability study with two pantoprazole delayed-released tablet formulations administered with and without food in healthy subjects.

T. Monif, G. De Nucci, G. Mendes, 2011, Arzneimittel-Forschung.

Negative chronotropic response to adenosine receptor stimulation in rat right atria after run training

F. Priviero, G. De Nucci, A. Zanesco, 2004, Clinical and experimental pharmacology & physiology.

Role of nitric oxide on the increased vascular permeability and neutrophil accumulation induced by staphylococcal enterotoxin B into the mouse paw.

G. De Nucci, E. Antunes, S. Teixeira, 2001, Biochemical pharmacology.

Effects of Amphetamine on Immune-Mediated Lung Inflammatory Response in Rats

J. Palermo-neto, G. De Nucci, M. Muscará, 2004, Neuroimmunomodulation.

Comparative Bioavailability of Two Different Diclofenac Formulations in Healthy Volunteers

G. De Nucci, F. Lerner, L. Silva, 1999, Arzneimittelforschung.

A Phase I clinical trial of lodenafil carbonate, a new phosphodiesterase Type 5 (PDE5) inhibitor, in healthy male volunteers.

G. De Nucci, K. Alkharfy, G. Mendes, 2012, International journal of clinical pharmacology and therapeutics.

Heparin, Polycations, and Atherosclerosis

G. De Nucci, S. Hyslop, 1993, Seminars in thrombosis and hemostasis.

Effect of Endothelin‐1 on Arterioles and Venules in vivo

Z. Fortes, G. De Nucci, J. Garcia-Leme, 1989, Journal of cardiovascular pharmacology.

R. Zatz, G. De Nucci, E. Antunes, 1995, Prostaglandins, leukotrienes, and essential fatty acids.

Quantification of nimesulide in human plasma by high-performance liquid chromatography/tandem mass spectrometry. Application to bioequivalence studies.

G. De Nucci, R. Moreno, M. Muscará, 2001, Journal of mass spectrometry : JMS.

Measurement of 6-cyanodopamine, 6-nitrodopa, 6-nitrodopamine and 6-nitroadrenaline by LC-MS/MS in Krebs-Henseleit solution. Assessment of basal release from rabbit isolated right atrium and ventricles.

G. Caliendo, G. De Nucci, Larryn W. Peterson, 2023, Biomedical chromatography : BMC.

Q817G mutation in phosphodiesterase type 5: Conformational analysis and dissociation profile of the inhibitor Tadalafil

C. H. Lescano, G. De Nucci, Ivan Pires de Oliveira, 2019, Chemical biology & drug design.

Impact of Bariatric Surgery on the Pharmacokinetics Parameters of Amoxicillin

G. De Nucci, G. Mendes, M. D. de Moraes, 2018, Obesity Surgery.

Clarithromycin bioequivalence study of two oral formulations in healthy human volunteers.

G De Nucci, F E Lerner, G Caliendo, 2000, International journal of clinical pharmacology and therapeutics.

A bioequivalence study of gliclazide based on quantification by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.

G D Mendes, L D Moreira, A dos S Pereira, 2005, International journal of clinical pharmacology and therapeutics.

Bioavailability of four pharmaceutical formulations of metronidazole tested on normal healthy volunteers.

G. De Nucci, M. Muscará, 1991, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Comparative bioavailability study with two sodium valproate tablet formulations administered under fasting conditions in healthy subjects.

G. De Nucci, G. Mendes, N. Antunes, 2022, International journal of clinical pharmacology and therapeutics.

Identification and human pharmacokinetics of dihydroergotoxine metabolites in man: preliminary results

S. Lilla, G. De Nucci, B. Bicalho, 2008, Biopharmaceutics & drug disposition.

Pharmacokinetics of dihydroergocristine and its major metabolite 8'-hydroxy-dihydroergocristine in human plasma.

G. Caliendo, E. Perissutti, S. Lilla, 2005, Current drug metabolism.

In vivo inhibition of nitric oxide synthesis does not depend on renin-angiotensin system activation.

R. Zatz, G. De Nucci, E. Antunes, 1996, European journal of pharmacology.

A comparative study on the anti-inflammatory effects of single oral doses of naproxen and its hydrogen sulfide (H2S)-releasing derivative ATB-346 in rats with carrageenan-induced synovitis

J. Wallace, G. De Nucci, M. Muscará, 2013, Medical gas research.

Nitric oxide release may be involved in the microcirculatory response to acetylcholine.

G. De Nucci, D. Nigro, M. Carvalho, 1990, European journal of pharmacology.

Alpha1-adrenergic antagonists block 6-nitrodopamine contractions on the rat isolated epididymal vas deferens.

G. De Nucci, F. Mónica, A. Fregonesi, 2021, European Journal of Pharmacology.

QSAR models for inhibitors of physiological impact of Escherichia coli that leads to diarrhea.

G. Gini, E. Benfenati, J. Leszczynski, 2013, Biochemical and biophysical research communications.

The effect of a 1-week administration of cetirizine on the chemotaxis and superoxide anion production of neutrophils from healthy volunteers.

A Condino-Neto, M N Muscara, P T Bozza, 1996, International journal of clinical pharmacology and therapeutics.

Role of Substance P and Bradykinin in Acute Pancreatitis Induced by Secretory Phospholipase A2

G. De Nucci, E. Antunes, M. Ribela, 2008, Pancreas.

Comparative effect of Phoneutria nigriventer spider venom and capsaicin on the rat paw oedema.

A. Gambero, G. De Nucci, E. Antunes, 2001, Life sciences.

Endothelin‐1 Causes Vasoconstriction and Vasodilation in the Blood Perfused Liver of the Dog

J. Vane, G. De Nucci, P. Withrington, 1989, Journal of cardiovascular pharmacology.

Propylthiouracil quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry: application in a bioequivalence study.

E. Perissutti, G. De Nucci, F. Frecentese, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.