David J. Polhemus

发表

Nebivolol Acts as a S-Nitrosoglutathione Reductase Inhibitor

N. Bryan, D. Lefer, K. Islam, 2016, Journal of cardiovascular pharmacology and therapeutics.

Effects of storage‐aged red blood cell transfusions on endothelial function in hospitalized patients

James L. Newman, A. Quyyumi, D. Lefer, 2014, Transfusion.

Vasomotor Function Comparative Assessment at 1 and 2 Years Following Implantation of the Absorb Everolimus-Eluting Bioresorbable Vascular Scaffold and the Xience V Everolimus-Eluting Metallic Stent in Porcine Coronary Arteries: Insights From In Vivo Angiography, Ex Vivo Assessment, and Gene Analysis

A. Quyyumi, D. Giddens, B. Gogas, 2016, JACC. Cardiovascular interventions.

Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling to Preserve Kidney Function and Improve Exercise Tolerance in Heart Failure

D. Lefer, M. Xian, David J. Polhemus, 2018, JACC. Basic to translational science.

Hydrogen Sulfide Attenuates Cardiac Dysfunction After Heart Failure Via Induction of Angiogenesis

T. Murohara, S. Bhushan, J. Calvert, 2013, Circulation. Heart failure.

Restoration of Hydrogen Sulfide Production in Diabetic Mice Improves Reparative Function of Bone Marrow Cells

D. Lefer, R. Kishore, J. Rabinowitz, 2016, Circulation.

Sodium Nitrite Fails to Limit Myocardial Infarct Size: Results from the CAESAR Cardioprotection Consortium (LB645)

Steven P Jones, Carlos C. Chang, R. Bolli, 2014 .

Zofenopril Protects Against Myocardial Ischemia–Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability

D. Lefer, G. Cirino, K. Islam, 2016, Journal of the American Heart Association.

Renal Denervation Prevents Heart Failure Progression Via Inhibition of the Renin-Angiotensin System.

D. Lefer, C. White, J. Reilly, 2018, Journal of the American College of Cardiology.

Radiofrequency Renal Denervation Protects the Ischemic Heart via Inhibition of GRK2 and Increased Nitric Oxide Signaling

D. Lefer, K. Mcdonough, Juan Gao, 2016, Circulation research.

Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome.

Carlos C. Chang, I. Pipinos, J. Calvert, 2015, American journal of physiology. Heart and circulatory physiology.

Nitric Oxide Contributes to Vasomotor Tone in Hypertensive African Americans Treated With Nebivolol and Metoprolol

A. Quyyumi, D. Lefer, E. Veledar, 2016, Journal of clinical hypertension.

Repeated cell transplantation and adjunct renal denervation in ischemic heart failure: exploring modalities for improving cell therapy efficacy

E. Marbán, D. Lefer, David J. Polhemus, 2019, Basic Research in Cardiology.

Choline Diet and Its Gut Microbe–Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload–Induced Heart Failure

S. Hazen, S. Bhushan, D. Lefer, 2016, Circulation. Heart failure.

Analysis of erectile responses to H2S donors in the anesthetized rat.

Taylor C Peak, David J. Polhemus, P. Kadowitz, 2015, American journal of physiology. Heart and circulatory physiology.

A novel mtDNA repair fusion protein attenuates maladaptive remodeling and preserves cardiac function in heart failure.

S. Bhushan, D. Lefer, G. Wilson, 2017, American journal of physiology. Heart and circulatory physiology.

Evolution of Hydrogen Sulfide Therapeutics to Treat Cardiovascular Disease

D. Lefer, David J. Polhemus, Zhen Li, 2018, Circulation research.

Nitrite Therapy Improves Left Ventricular Function During Heart Failure via Restoration of Nitric Oxide–Mediated Cytoprotective Signaling

J. Butler, T. Murohara, S. Bhushan, 2014, Circulation research.

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

Paul L Huang, S. Bhushan, J. Calvert, 2014, Proceedings of the National Academy of Sciences.

messengers in cerebrovascular circulation Carbon monoxide and hydrogen sulfide: gaseous

D. Lefer, L. Brewster, W. Arendshorst, 2015 .

Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease.

D. Lefer, David J. Polhemus, 2014, Circulation research.

Hydrogen Sulfide Levels and Nuclear Factor-Erythroid 2-Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI)

D. Lefer, L. Brewster, K. Islam, 2015, Journal of the American Heart Association.

Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure

S. Hazen, D. Lefer, W. Tang, 2020, Journal of the American Heart Association.

Combined Angiotensin Receptor–Neprilysin Inhibitors Improve Cardiac and Vascular Function Via Increased NO Bioavailability in Heart Failure

H. Koiwaya, D. Lefer, David J. Polhemus, 2018, Journal of the American Heart Association.

A Novel Hydrogen Sulfide Prodrug, SG1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

H. Krum, T. Giordano, David J. Polhemus, 2015, Cardiovascular therapeutics.

Renal Sympathetic Denervation Protects the Failing Heart Via Inhibition of Neprilysin Activity in the Kidney.

D. Lefer, K. Varner, H. Xia, 2017, Journal of the American College of Cardiology.

Effects of a novel hydrogen sulfide prodrug in a porcine model of acute limb ischemia.

D. Lefer, David J. Polhemus, Zhen Li, 2019, Journal of vascular surgery.

Sustained release nitrite therapy results in myocardial protection in a porcine model of metabolic syndrome with peripheral vascular disease.

D. Lefer, L. Brewster, K. Islam, 2015, American journal of physiology. Heart and circulatory physiology.

Hydrogen Sulfide as a Potential Therapy for Heart Failure—Past, Present, and Future

D. Lefer, David J. Polhemus, Zhen Li, 2021, Antioxidants.

The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure

J. Butler, J. Calvert, D. Lefer, 2014, Scientifica.

Novel Göttingen Miniswine Model of Heart Failure With Preserved Ejection Fraction Integrating Multiple Comorbidities

D. Lefer, David J. Polhemus, Zhen Li, 2021, JACC. Basic to translational science.

Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a "2-Hit" Murine Model.

Ravi B. Patel, D. Lefer, H. Xia, 2023, Journal of the American Heart Association.

Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury

J. Pfeilschifter, D. Lefer, H. Xia, 2020, Journal of the American Heart Association.