Jiaoyang Jiang

发表

Structure of human O-GlcNAc transferase and its complex with a peptide substrate

Piotr Sliz, Yunsun Nam, P. Sliż, 2010, Nature.

Isolation and characterization of the gene associated with geosmin production in cyanobacteria.

D. Cane, C. Saint, S. Giglio, 2008, Environmental science & technology.

Deciphering the Functions of Protein O-GlcNAcylation with Chemistry.

Jiaoyang Jiang, Matthew Worth, Hao Li, 2017, ACS chemical biology.

Structural characterization of the O-GlcNAc cycling enzymes: insights into substrate recognition and catalytic mechanisms.

S. Walker, Jiaoyang Jiang, Hao Li, 2019, Current opinion in structural biology.

Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe.

Jiaoyang Jiang, Matthew Worth, Hao Li, 2020, International journal of biological macromolecules.

Targeted covalent inhibition of O-GlcNAc transferase in cells.

Jiaoyang Jiang, Matthew Worth, Hao Li, 2019, Chemical communications.

Geosmin biosynthesis. Streptomyces coelicolor germacradienol/germacrene D synthase converts farnesyl diphosphate to geosmin.

D. Cane, Jiaoyang Jiang, X. He, 2006, Journal of the American Chemical Society.

The Emerging Roles of Protein Interactions with O-GlcNAc Cycling Enzymes in Cancer

Jinshan Xie, Jiaoyang Jiang, Chia-Wei Hu, 2022, Cancers.

A small molecule that inhibits OGT activity in cells.

Damien Y. Duveau, Rodrigo F. Ortiz-Meoz, S. Walker, 2015, ACS chemical biology.

Distributive O-GlcNAcylation on the Highly Repetitive C-Terminal Domain of RNA Polymerase II.

Zhi-Xiong Ma, Jiaoyang Jiang, Matthew Worth, 2016, Biochemistry.

Molecular Interrogation to Crack the Case of O-GlcNAc.

Jiaoyang Jiang, Arielis Estevez, Dongsheng Zhu, 2020, Chemistry.

HCF-1 Is Cleaved in the Active Site of O-GlcNAc Transferase

W. Herr, S. Walker, D. Vocadlo, 2013, Science.

Geosmin biosynthesis. Mechanism of the fragmentation-rearrangement in the conversion of germacradienol to geosmin.

D. Cane, Jiaoyang Jiang, 2008, Journal of the American Chemical Society.

Identification of (8S,9S,10S)-8,10-dimethyl-1-octalin, a key intermediate in the biosynthesis of geosmin in bacteria.

Jeroen S. Dickschat, D. Cane, R. Müller, 2008, Journal of the American Chemical Society.

Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme.

D. Cane, Jiaoyang Jiang, Xiaofei He, 2007, Nature chemical biology.

Genome mining in Streptomyces avermitilis: A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree.

M. Komatsu, H. Ikeda, D. Cane, 2009, Biochemistry.

PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis

I. Ong, Wei Xu, Guojun Chen, 2017, Nature Cell Biology.

A Neutral Diphosphate Mimic Crosslinks the Active Site of Human O-GlcNAc Transferase

S. Walker, M. Lazarus, Jiaoyang Jiang, 2011, Nature chemical biology.

Chemical and Biochemical Strategies To Explore the Substrate Recognition of O‐GlcNAc‐Cycling Enzymes

Jiaoyang Jiang, Matthew Worth, Hao Li, 2018, Chembiochem : a European journal of chemical biology.

Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode

Jiaoyang Jiang, Baobin Li, Hao Li, 2017, Nature Structural &Molecular Biology.

Structural snapshots of the reaction coordinate for O-GlcNAc transferase

S. Walker, D. Vocadlo, M. Lazarus, 2012, Nature chemical biology.

Cancer-derived mutation in the OGA stalk domain promotes cell malignancy through dysregulating PDLIM7 and p53

Jinshan Xie, Jiaoyang Jiang, Zhengwei Chen, 2023, Research square.

Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase

Jiaoyang Jiang, Baobin Li, Hao Li, 2017, Nature Communications.

Nucleocytoplasmic Protein Glycosylation

Jinshan Xie, Jiaoyang Jiang, C. Blankenship, 2020 .

Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase

Ziqing Lin, Ying Ge, Lingjun Li, 2017, Nature chemical biology.

Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.

D. Cane, D. Christianson, T. Zakharian, 2008, Archives of biochemistry and biophysics.

A novel binding site on the cryptic intervening domain is a motif-dependent regulator of O-GlcNAc transferase

Jinshan Xie, Y. Ivarsson, Jiaoyang Jiang, 2023, Research square.

Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase

Jiaoyang Jiang, Baobin Li, Hao Li, 2017, Nature Communications.

Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase

Jinshan Xie, Y. Ivarsson, Jiaoyang Jiang, 2023, Nature Chemical Biology.