H. Fung

发表

C. Rhodes, S. K. Yap, H. Fung, 1975 .

Arterial versus venous metabolism of nitroglycerin to nitric oxide: a possible explanation of organic nitrate venoselectivity.

J. Bauer, H. Fung, 1996, Journal of cardiovascular pharmacology.

Mechanisms for the pharmacologic interaction of organic nitrates with thiols. Existence of an extracellular pathway for the reversal of nitrate vascular tolerance by N-acetylcysteine.

H. Fung, M. Kakemi, K. Hough, 1988, The Journal of pharmacology and experimental therapeutics.

Tolerance to the Circulatory Effects of Oral Isosorbide Dinitrate: Rate of Development and Cross–tolerance to Glyceryl Trinitrate

J. Parker, U. Thadani, H. Fung, 1980, Circulation.

Pharmacology of Nitrovasodilators

H. Fung, Nathaniel A. Page, 2011 .

Blood vessel uptake and metabolism of organic nitrates in the rat.

H. Fung, A. Kamiya, S. C. Sutton, 1984, The Journal of pharmacology and experimental therapeutics.

Identification of the subcellular site for nitroglycerin metabolism to nitric oxide in bovine coronary smooth muscle cells.

H. Fung, S. Chung, 1990, The Journal of pharmacology and experimental therapeutics.

Reversed-phase high-performance liquid chromatography method for the analysis of nitro-arginine in rat plasma and urine.

H L Fung, H. Fung, M A Tabrizi-Fard, 1996, Journal of chromatography. B, Biomedical applications.

Effects of Nitro-L-Arginine on Blood Pressure and Cardiac Index in Anesthetized Rats: A Pharmacokinetic-Pharmacodynamic Analysis

H. Fung, M. Tabrizi-Fard, 1998, Pharmaceutical Research.

Pharmacokinetics, plasma protein binding and urinary excretion of Nω‐nitro‐L‐arginine in rats

H. Fung, M. Tabrizi-Fard, 1994 .

Tolerance: An Historical Overview

U. Elkayam, J. Abrams, U. Thadani, 1998 .

Nitric oxide donors: biochemical pharmacology and therapeutics.

J. Bauer, H. Fung, B. P. Booth, 1995, Advances in pharmacology.

Domestic dog health worsens with socio-economic deprivation of their home communities.

L. F. Chaves, N. Gottdenker, A. Saldaña, 2014, Acta tropica.

Effects of repeated in vivo inhalant nitrite exposure on gene expression in mouse liver and lungs.

D. Brazeau, H. Fung, D. Tran, 2006, Nitric oxide : biology and chemistry.

Concurrent Hydralazine Administration Prevents Nitroglycerin‐Induced Hemodynamic Tolerance in Experimental Heart Failure

J. Bauer, H. Fung, 1991, Circulation.

Use of an in Vitro Model for the Assessment of Muscle Damage from Intramuscular Injections: in Vitro-in Vivo Correlation and Predictability with Mixed Solvent Systems

H. Fung, G. Brazeau, 1989, Pharmaceutical Research.

Identification of nitroglycerin-induced cysteine modifications of pro-matrix metalloproteinase-9.

A. S. Krishnatry, Hao Wang, H. Fung, 2011, Rapid communications in mass spectrometry : RCM.

Inverse targeting of peritoneal tumors: selective alteration of the disposition of methotrexate through the use of anti-methotrexate antibodies and antibody fragments.

H. Fung, J. Balthasar, 1996, Journal of pharmaceutical sciences.

The effects of dietary calcium on lead absorption, distribution, and elimination kinetics in rats.

B. Aungst, H. Fung, 1985, Journal of toxicology and environmental health.

Metabolites decrease the plasma clearance of isosorbide dinitrate in rats.

H. Fung, S. C. Sutton, 1984, Biopharmaceutics & drug disposition.

Pharmacodynamic modeling of thein vitro vasodilating effects of organic mononitrates

H. Fung, T. Tzeng, 1992, Journal of Pharmacokinetics and Biopharmaceutics.

Oral isosorbide dinitrate in angina pectoris: comparison of duration of action an dose-response relation during acute and sustained therapy.

J. Parker, U. Thadani, H. Fung, 1982, The American journal of cardiology.

Biochemical mechanism of organic nitrate action.

J. Bauer, H. Fung, S. Chung, 1992, The American journal of cardiology.

Mechanisms of nitrate tolerance

J. Bauer, H. Fung, 1994, Cardiovascular Drugs and Therapy.

Tolerance to isosorbide dinitrate: rate of development and reversal.

J. Parker, H. Fung, D. Ruggirello, 1983, Circulation.

Kinetics of isosorbide dinitrate and relationships to pharmacological effects.

J. Parker, U. Thadani, H. Fung, 1981, British journal of clinical pharmacology.

Mechanism-based partial inactivation of glutathione S-transferases by nitroglycerin: tyrosine nitration vs sulfhydryl oxidation.

H. Fung, W. Lee, 2003, Nitric oxide : biology and chemistry.

Prazosin Potentiates the Acute Hypotensive Effects of Nitroglycerin but Does Not Attenuate Nitrate Tolerance in Normal Conscious Rats

H. Fung, E. Wang, 2004, Journal of cardiovascular pharmacology.

In vivo disposition of 3-nitro-L-tyrosine in rats: implications on tracking systemic peroxynitrite exposure.

T. Maurer, H. Fung, M. Tabrizi-Fard, 1999, Drug metabolism and disposition: the biological fate of chemicals.

The effect of dose on the disposition of lead in rats after intravenous and oral administration.

B. Aungst, H. Fung, J. A. Dolce, 1981, Toxicology and applied pharmacology.

eNOS-dependent vascular interaction between nitric oxide and calcitonin gene-related peptide in mice: gender selectivity and effects on blood aggregation

H. Fung, Ye Xu, W. Lee, 2003, Regulatory Peptides.

Antianginal effects of intravenous nitroglycerin over 24 hours.

N. Reichek, P. Douglas, H. Fung, 1988, Circulation.

Pharmacokinetics and pharmacodynamics of organic nitrates.

H. Fung, 1987, The American journal of cardiology.

Pharmacokinetics and pharmacodynamics of isosorbide dinitrate.

H. Fung, 1985, American heart journal.

Vascular Pharmacokinetics of Nitrates

H. Fung, A. Kamiya, S. C. Sutton, 1985 .

Transdermal isosorbide dinitrate in angina pectoris: effect of acute and sustained therapy.

J. Parker, H. Fung, K. A. Vankoughnett, 1984, The American journal of cardiology.

Transdermal Nitroglycerin in Angina Pectoris

J. Parker, H. Fung, 1984, The American journal of cardiology.

Pharmacokinetic determinants of nitrate action.

H. Fung, 1984, The American journal of medicine.

Pharmacokinetics of Isosorbide Dinitrate During Tolerance Development

H. Fung, 1983 .

Pharmacokinetics of nitroglycerin and long-acting nitrate esters.

H. Fung, 1983, The American journal of medicine.

Improved GLC determination of plasma nitroglycerin concentrations.

H. Fung, P. Yap, E. McNiff, 1978, Journal of pharmaceutical sciences.

Oral Isosorbide Dinitrate in the Treatment of Angina Pectoris: Dose‐Response Relationship and Duration of Action During Acute Therapy

J. Parker, U. Thadani, H. Fung, 1980, Circulation.

Effects of obesity on the pharmacodynamics of nitroglycerin in conscious rats

H. Fung, E. Wang, 2008, AAPS PharmSci.

Estimation of nitric oxide synthase activity via LC-MS/MS determination of 15 N 3 -citrulline in biological samples

Soyoung Shin, B. Shin, H. Fung, 2015 .

Evaluation of an LC-MS/MS assay for 15N-nitrite for cellular studies of L-arginine action.

Soyoung Shin, H. Fung, 2011, Journal of pharmaceutical and biomedical analysis.

Nitroglycerin‐inhibited whole blood aggregation is partially mediated by calcitonin gene‐related peptide–a neurogenic mechanism

T. Nolan, H. Fung, B. P. Booth, 1997, British journal of pharmacology.

Sustained antiplatelet properties of nitroglycerin during hemodynamic tolerance in rats.

J. Bauer, H. Fung, S. Jacob, 1996, Journal of cardiovascular pharmacology.

Pharmacokinetic‐hemodynamic interactions between vasopressin and nitroglycerin: Comparison between intravenous and cutaneous routes of nitrate delivery

G. Robertson, A. Blei, J. Gottstein, 1985, Hepatology.

Dissociation between Superoxide Accumulation and Nitroglycerin-Induced Tolerance

H. Fung, P. Tsou, V. Addanki, 2007, Journal of Pharmacology and Experimental Therapeutics.

Biochemical mechanism of nitroglycerin action and tolerance: is this old mystery solved?

H. Fung, 2004, Annual review of pharmacology and toxicology.

Intravenous Nitroglycerin in the Treatment of Spontaneous Angina Pectoris: A Prospective, Randomized Trial

J. Heinsimer, E. Lozner, G. Curfman, 1983, Circulation.

Effects of chronic oral administration on the disposition of laevodopa and its major metabolites in the plasma of the rat.

H. Fung, L. K. Cheng, L. Cheng, 1975, Xenobiotica; the fate of foreign compounds in biological systems.

Systemic biochemical effects of inhaled NO in rats: increased expressions of NOS III, nitrotyrosine-, and phosphotyrosine-immunoreactive proteins in liver and kidney tissues.

H. Fung, W. Kielbasa, 2001, Nitric oxide : biology and chemistry.

Mechanisms of creatine kinase release from isolated rat skeletal muscles damaged by propylene glycol and ethanol.

H. Fung, G. Brazeau, 1990, Journal of pharmaceutical sciences.

Effect of Apparent Elimination Half-Life on Nitroglycerin-Induced Hemodynamic Rebound in Experimental Heart Failure

J. Bauer, H. Fung, 1993, Pharmaceutical Research.

Effects of Inhalant Nitrites on VEGF Expression: A Feasible Link to Kaposi's Sarcoma?

H. Fung, D. Tran, 2006, Journal of Neuroimmune Pharmacology.

Organic nitrate metabolism and action: toward a unifying hypothesis and the future-a dedication to Professor Leslie Z. Benet.

H. Fung, Nathaniel A. Page, 2013, Journal of pharmaceutical sciences.

Nitrite inhalation in rats elevates tissue NOS III expression and alters tyrosine nitration and phosphorylation.

H. Fung, W. Kielbasa, 2000, Biochemical and biophysical research communications.

Pharmacokinetic and pharmacodynamic optimization of intraperitoneal chemotherapy.

H. Fung, J. Balthasar, 1996, Life sciences.

Mechanism of Cellular Oxidation Stress Induced by Asymmetric Dimethylarginine

H. Fung, Srinidi Mohan, 2012, International journal of molecular sciences.

Calcitonin gene-related peptide-dependent vascular relaxation of rat aorta. An additional mechanism for nitroglycerin.

H. Fung, M. Tabrizi-Fard, B. P. Booth, 2000, Biochemical pharmacology.

Abbreviated Bioavailability Monograph: Conjugated Estrogens

H. Fung, J. A. Seitz, L. Pagliaro, 1977 .

Thiol-mediated catalysis of nitroglycerin degradation by serum proteins. Increase in metabolism was not accompanied by S-nitrosothiol production.

H. Fung, S. Chong, 1990, Drug metabolism and disposition: the biological fate of chemicals.

Regulation of K+ and Ca2+ channels in experimental cardiac failure.

D. Triggle, M. Gopalakrishnan, J. Bauer, 1991, The American journal of physiology.

Stability of nitroglycerin in human and rat plasma

H. Fung, G. Maier, A. Poliszczuk, 1979 .

Specificity of nitroglycerin assays.

R. A. Morrison, H. Fung, 1979, Journal of pharmaceutical sciences.

Role of Glutaredoxin-Mediated Protein S-Glutathionylation in Cellular Nitroglycerin Tolerance

H. Fung, P. Tsou, Nathaniel A. Page, 2009, Journal of Pharmacology and Experimental Therapeutics.

Clinical pharmacology of organic nitrates.

H. Fung, 1993, The American journal of cardiology.

Kinetic mechanisms for the concentration dependency of in vitro degradation of nitroglycerin and glyceryl dinitrates in human blood: metabolite inhibition or cosubstrate depletion?

H. Fung, S. Chong, 1989, Journal of pharmaceutical sciences.

Effect of intermittent exposure and drug-free intervals on the in vitro vascular tolerance to nitroglycerin.

H. Fung, K. Hough, E. Kowaluk, 1989, Life sciences.

Photochemical generation of nitric oxide from nitro-containing compounds: possible relation to vascular photorelaxation phenomena.

J. Bauer, H. Fung, 1994, Life sciences.

Pharmacokinetics of pentaerythritol tetranitrate following intra-arterial and oral dosing in the rat.

H. Fung, S. P. King, S. King, 1986, Journal of pharmaceutical sciences.

Examination of N-hydroxylation as a prerequisite mechanism of nitric oxide synthase inactivation.

T. Maurer, J. Pan, H. Fung, 2000, Bioorganic & medicinal chemistry letters.

Nitroglycerin pharmacokinetics after intravenous infusion in normal subjects.

A. Yacobi, H. Fung, A. Goldfarb, 1981, Journal of pharmaceutical sciences.

L. L. Michaelis, E. Rossi, P. Patrignani, 1985, Anesthesia and analgesia.

Spontaneous liberation of nitric oxide cannot account for in vitro vascular relaxation by S-nitrosothiols.

H. Fung, E. Kowaluk, 1990, The Journal of pharmacology and experimental therapeutics.

Keywords organic nitrates mechanisms of action potency pharmacokinetics pharmacodynamics

H. Fung, 2006 .

Chemical Stabilization of a Vasoactive S-Nitrosothiol with Cyclodextrins Without Loss of Pharmacologic Activity

J. Bauer, H. Fung, 1991, Pharmaceutical Research.

Do nitrates differ?

H. Fung, 1992, British journal of clinical pharmacology.

Intracellular L-arginine concentration does not determine NO production in endothelial cells: implications on the "L-arginine paradox".

Soyoung Shin, H. Fung, Srinidi Mohan, 2011, Biochemical and biophysical research communications.

Tolerance to relaxation in rat aorta: comparison of an S-nitrosothiol with nitroglycerin.

H. Fung, E. Kowaluk, R. Poliszczuk, 1987, European journal of pharmacology.

Pharmacokinetics of Stereomeric 1,4:3,6-Dianhydrohexitol Mononitrates in Rats

H. Fung, T. Tzeng, 2004, Pharmaceutical Research.

Pharmacokinetics of oral L‐isoidide mononitrate in rats

H. Fung, T. Tzeng, 1993, Biopharmaceutics & drug disposition.

Effect of organic cosolvent-induced skeletal muscle damage on the bioavailability of intramuscular [14C]diazepam.

H. Fung, G. Brazeau, 1990, Journal of pharmaceutical sciences.

Percutaneous nitroglycerin absorption in rats.

H. Fung, S. Horhota, 1979, Journal of pharmaceutical sciences.

Pharmacodynamics of In Vivo Nitrate Action

J. Bauer, H. Fung, B. P. Booth, 1998 .

Continuous exposure to l-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells

Soyoung Shin, H. Fung, Chia-Ching Wu, 2012, Amino Acids.

Hemodynamic evaluation of isosorbide dinitrate in alcoholic cirrhosis. Pharmacokinetic-hemodynamic interactions.

R. Groszmann, D. Ganger, P. Kahrilas, 1987, Gastroenterology.

Vascular and hemodynamic differences between organic nitrates and nitrites.

T. Nolan, J. Bauer, H. Fung, 1997, The Journal of pharmacology and experimental therapeutics.

Specific binding of nitroglycerin to coronary artery microsomes. Evidence of a vascular nitrate binding site.

J. Bauer, H. Fung, 1996, Biochemical pharmacology.

Differential hemodynamic effects and tolerance properties of nitroglycerin and an S-nitrosothiol in experimental heart failure.

J. Bauer, H. Fung, 1991, The Journal of pharmacology and experimental therapeutics.

Effects of chronic glyceryl trinitrate on left ventricular haemodynamics in a rat model of congestive heart failure: demonstration of a simple animal model for the study of in vivo nitrate tolerance.

J. Bauer, H. Fung, 1990, Cardiovascular research.

Mechanisms of nitrate action and vascular tolerance.

H. Fung, S. Chong, E. Kowaluk, 1989, European heart journal.

Plasma nitroglycerin levels after sublingual, oral and topical administration.

H. Blumenthal, S. K. Yap, H. Fung, 1977, British journal of clinical pharmacology.

Contribution of vascular tissue to the antiplatelet activity of sodium nitroprusside.

H. Fung, B. P. Booth, 1998, Journal of cardiovascular pharmacology.

Rectal absorption of nitroglycerin in the rat: avoidance of first-pass metabolism as a function of rectal length exposure.

H. Fung, H. Ogata, A. Kamiya, 1982, Journal of pharmaceutical sciences.

Improved pharmacological activity via pro-drug modification: comparative pharmacokinetics of sodium gamma-hydroxybutyrate and gamma-butyrolactone.

J. Lettieri, H. Fung, 1978, Research communications in chemical pathology and pharmacology.

Evaluation and development of gas chromatographic procedures for the determination of γ-hydroxybutyric acid and γ-butyrolactone in plasma

J. Lettieri, H. Fung, 1978 .

Molecular interactions and solubility of polar nonelectrolytes in nonpolar solvents.

T. Higuchi, H. Fung, 1971, Journal of pharmaceutical sciences.

Influence of hydrophobicity on the ion exchange selectivity coefficients for aromatic amines.

H. Fung, M. B. Kril, 1990, Journal of pharmaceutical sciences.

Dehydration of crystalline theophylline monohydrate and ampicillin trihydrate.

E. Shefter, H. Fung, O. Mok, 1973, Journal of pharmaceutical sciences.

Functional group contribution in ion-pair extraction of tricyclic amines.

H. Fung, Y. H. Ow, 1972, Journal of pharmaceutical sciences.

Site dependence for topical absorption of nitroglycerin in rats.

H. Fung, S. Horhota, 1978, Journal of pharmaceutical sciences.

Potency and stability of extemporaneous nitroglycerin infusions.

H. Fung, E. McNiff, B. L. McNiff, 1979, American journal of hospital pharmacy.

Differential Metabolism of Organic Nitrates by Aldehyde Dehydrogenase 1a1 and 2: Substrate Selectivity, Enzyme Inactivation, and Active Cysteine Sites

W. Keung, H. Fung, P. Tsou, 2011, The AAPS Journal.

Intramolecular bifunctional facilitation in complex molecules. Combined nucleophilic and general acid participation in hydrolysis of hexchlorophene monosuccinate

T. Higuchi, H. Fung, H. Takechi, 1971 .

Potency and stability of extemporaneously prepared nitroglycerin intravenous solutions.

H. Fung, 1978, American journal of hospital pharmacy.

Effect of Dosage Regimen on the Development of Tolerance to Nitroglycerin in Rats

H L Fung, S C Sutton, H. Fung, 1983, Journal of cardiovascular pharmacology.

A Modified Product Inhibition Model Describes the Nonlinear Pharmacokinetics of Nicorandil in Rats

H. Fung, Lin Zhao, S. Chung, 1994, Pharmaceutical Research.

High-performance liquid chromatographic method for stability and pharmacokinetic studies of nicorandil.

H. Fung, E. L. Bachert, 1993, Journal of chromatography.

Nitroglycerin‐induced relaxation of anorectal smooth muscle: evidence for apparent lack of tolerance development in the anaesthetized rat

H. Fung, E. Q. Wang, David M Soda, 2001, British journal of pharmacology.

An In Vitro Model to Evaluate Muscle Damage Following Intramuscular Injections

H. Fung, G. Brazeau, 1989, Pharmaceutical Research.

Beneficial effects of intraluminal nitroglycerin in intestinal ischemia-reperfusion injury in rats.

M. Caty, H. Fung, J. Rossman, 2003, The Journal of surgical research.

Absorption and first-pass metabolism of 14C-gamma-hydroxybutyric acid.

J. Lettieri, H. Fung, 1976, Research communications in chemical pathology and pharmacology.

Absorption of Sodium γ-hydroxybutyrate and its Prodrug γ-butyrolactone: Relationship Between in vitro Transport and in Vivo Absorption

H. Fung, C. Arena, 1980 .

Liquid chromatographic-mass spectrometric determination of endogenous gamma-hydroxybutyrate concentrations in rat brain regions and plasma.

J. Raybon, H. Fung, S. Fung, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Dose-dependent pharmacokinetics and hypnotic effects of sodium gamma-hydroxybutyrate in the rat.

J. Lettieri, H. Fung, 1979, The Journal of pharmacology and experimental therapeutics.

Metabolic activation of sodium nitroprusside to nitric oxide in vascular smooth muscle.

H L Fung, P. Seth, H. Fung, 1992, The Journal of pharmacology and experimental therapeutics.

Analysis of isobutyl nitrite inhalant in rat and human blood: application for pharmacokinetic investigations.

J. Bauer, H. Fung, W. Kielbasa, 1999, Journal of chromatography. B, Biomedical sciences and applications.

Chapter 34. Biopharmaceutics and Pharmacokinetics

H. Fung, 1973 .

Continuous exposure to l-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells

Soyoung Shin, H. Fung, Chia-Ching Wu, 2012, Amino Acids.

Pharmacokinetics of nitroglycerin after parenteral and oral dosing in the rat.

H. Fung, H. Ogata, A. Kamiya, 1984, Journal of pharmaceutical sciences.

Attenuated nitric oxide synthase activity and protein expression accompany intestinal ischemia/reperfusion injury in rats.

M. Caty, H. Fung, J. Rossman, 2000, Biochemical and biophysical research communications.

Intestinal and hemodynamic impairment following mesenteric ischemia/reperfusion.

M. Caty, H. Fung, J. Rossman, 2001, The Journal of surgical research.

Perspectives on the history and scientific contributions of Gerhard Levy

W. Jusko, H. Fung, 2015, Journal of Pharmacokinetics and Pharmacodynamics.

Relationship between steady-state pharmacokinetics and hemodynamic effects of inhaled isobutyl nitrite in conscious rats

H. Fung, W. Kielbasa, 2000, AAPS PharmSci.

Inhalant nitrite exposure alters mouse hepatic angiogenic gene expression.

D. Brazeau, H. Fung, D. Tran, 2003, Biochemical and biophysical research communications.

Interpretation of nitrate plasma concentrations. Effect of cardiac output on nitroglycerin pharmacokinetics in experimental animals.

H. Fung, S. Chong, A. Blei, 1988, European heart journal.

Nitroglycerin alters matrix remodeling proteins in THP-1 human macrophages and plasma metalloproteinase activity in rats.

D. Brazeau, A. S. Krishnatry, H. Fung, 2011, Nitric oxide : biology and chemistry.

Effect of infusion administration set on the delivery rate and plasma concentration of nitroglycerin in dogs.

A. Yacobi, H. Fung, C. Lai, 1985, Journal of pharmaceutical sciences.

Statistical prediction of drug stability based on nonlinear parameter estimation.

H L Fung, S Y King, M S Kung, 1984, Journal of pharmaceutical sciences.

Simultaneous bioanalysis of L-arginine, L-citrulline, and dimethylarginines by LC-MS/MS.

Soyoung Shin, H. Fung, Srinidi Mohan, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Pharmacokinetics of 1,4-Butanediol in Rats: Bioactivation to γ-Hydroxybutyric Acid, Interaction with Ethanol, and Oral Bioavailability

H. Fung, J. Bulitta, D. Tran, 2008, The AAPS Journal.

Examination of the in vitro degradation of [14C] pentaerythritol tetranitrate in rat and human blood with an improved thin-layer radiochromatographic procedure.

H. Fung, S. King, 1985, Journal of chromatography.

Relationship between in vivo nitroglycerin metabolism and in vitro organic nitrate reductase activity in rats.

H. Fung, G. Maier, C. Arena, 1980, Biochemical pharmacology.

Pharmacokinetics of nitroglycerin in rats.

H. Fung, P. Yap, 1978, Journal of pharmaceutical sciences.

Kinetic characterization of in vitro lead transport across the rat small intestine: mechanism of intestinal lead transport.

B. Aungst, H. Fung, 1981, Toxicology and applied pharmacology.

Characterization of the pharmacokinetic interaction between nifedipine and ethanol in the rat.

K. Boje, H. Fung, 1989, The Journal of pharmacology and experimental therapeutics.

Hepatic extraction of isosorbide dinitrate in cardiac patients

T. Meinertz, R. A. Morrison, H. Fung, 1983, Clinical pharmacology and therapeutics.

Dissociation of nitrovasodilator-induced relaxation from cyclic GMP levels during in vitro nitrate tolerance.

H. Fung, E. Kowaluk, 1990, European journal of pharmacology.

Nitrosothiol and nitrate tolerance.

H. Fung, R. Poliszczuk, 1986, Zeitschrift fur Kardiologie.

cDNA Microarray analysis of vascular gene expression after nitric oxide donor infusion in rats: Implications for nitrate tolerance mechanisms

D. Brazeau, H. Fung, E. Wang, 2008, AAPS PharmSci.

Nonlinear pharmacokinetics of L‐NG‐methyl‐arginine in rats: characterization by an improved HPLC assay

T. Maurer, H. Fung, Y. Mishra, 1999, Biopharmaceutics & drug disposition.

Broad regulation of matrix and adhesion molecules in THP-1 human macrophages by nitroglycerin.

D. Brazeau, A. S. Krishnatry, H. Fung, 2010, Nitric oxide : biology and chemistry.

Use of refractometers to detect controlled-substance tampering.

H. Fung, S. Chong, J. G. Kitrenos, 1991, American journal of hospital pharmacy.

Biochemical characterization of a membrane-bound enzyme responsible for generating nitric oxide from nitroglycerin in vascular smooth muscle cells.

P. Seth, H. Fung, 1993, Biochemical pharmacology.

Pharmacodynamics of in Vivo Nitroglycerin Tolerance in Normal Conscious Rats: Effects of Dose and Dosing Protocol

H. Fung, J. Balthasar, E. Wang, 2004, Pharmaceutical Research.

Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice

H. Fung, E. Q. Wang, W. Lee, 2002, British journal of pharmacology.

Pharmacodynamic Models of Nitroglycerin-Induced Hemodynamic Tolerance in Experimental Heart Failure

John Anthony Bauer, J. Bauer, H. Fung, 1994, Pharmaceutical Research.

Erratum: Continuous versus intermittent nitroglycerin administration in experimental heart failure: Vascular relaxation and radioligand binding to adrenoceptors and ion channels (Journal of Cardiovascular Pharmacology (1993) 22 (600-608))

Ho-Leung Fung, D. J. Triggle, J. A. Bauer, 1994 .

Continuous Versus Intermittent Nitroglycerin Administration in Experimental Heart Failure: Vascular Relaxation and Radioligand Binding to Adrenoceptors and Ion Channels

Yong Wha Kwon, D. Triggle, M. Gopalakrishnan, 1993, Journal of Cardiovascular Pharmacology.

A common enzyme may be responsible for the conversion of organic nitrates to nitric oxide in vascular microsomes.

H. Fung, S. Chung, 1992, Biochemical and biophysical research communications.

Conversion of nitroglycerin to nitric oxide in microsomes of the bovine coronary artery smooth muscle is not primarily mediated by glutathione-S-transferases.

P. Seth, H. Fung, C. Jung, 1992, The Journal of pharmacology and experimental therapeutics.

Relationship between nitroglycerin-induced vascular relaxation and nitric oxide production. Probes with inhibitors and tolerance development.

H. Fung, S. Chung, 1993, Biochemical pharmacology.

Isosorbide dinitrate disposition in the rat: metabolite pharmacokinetics and interactions.

H L Fung, R A Morrison, R. A. Morrison, 1984, The Journal of pharmacology and experimental therapeutics.

Application of Pharmacodynamic Modeling for Designing Time-Variant Dosing Regimens to Overcome Nitroglycerin Tolerance in Experimental Heart Failure

John Anthony Bauer, J. Bauer, H. Fung, 1997, Pharmaceutical Research.

Determination of the partitioning, stability, and metabolite formation of isosorbide dinitrate in human and rat blood using an improved gas-liquid chromatographic assay.

R. A. Morrison, H. Fung, 1998, Journal of Chromatography A.

Removal of ammonia interference in the redox chemiluminescence assay of nitric oxide

H. Fung, S. Chung, 1992 .

Isosorbide dinitrate kinetics and dynamics after intravenous, sublingual, and percutaneous dosing in angina

T. Meinertz, R. A. Morrison, H. Fung, 1983, Clinical pharmacology and therapeutics.

Biochemical and pharmacological interactions between nitroglycerin and thiols. Effects of thiol structure on nitric oxide generation and tolerance reversal.

H. Fung, S. Chong, 1991, Biochemical pharmacology.

Differential sensitivity among nitric oxide donors toward ODQ-mediated inhibition of vascular relaxation.

H. Fung, M. Tabrizi-Fard, C. Tseng, 2000, The Journal of pharmacology and experimental therapeutics.

In vitro organic nitrate bioactivation to nitric oxide by recombinant aldehyde dehydrogenase 3A1.

H. Fung, Shun-hua Lin, Nathaniel A. Page, 2013, Nitric oxide : biology and chemistry.

Electrochemical characterization and determination of N-acetylpenicillamine thionitrite

E. Takeuchi, J. Osteryoung, H. Fung, 1985 .

Chapter 30 Pharmacokinetics and Drug Design

R. A. Morrison, B. Aungst, H. Fung, 1979 .

Prolonged plasma half-life after oral isosorbide dinitrate in patients with angina pectoris.

J. Parker, H. Fung, 1983, British journal of clinical pharmacology.

Differential interactions of nitric oxide donors with rat oxyhemoglobin.

H. Fung, M. Tabrizi-Fard, W. I. Lee, 1999, Biochemical pharmacology.

Organic nitrates in portal hypertension.

R. Groszmann, D. Ganger, H. Fung, 1988, European heart journal.

Validity of oral bioavailability estimates of phenolsulfonphthalein based on total urinary excretion from rats.

H. Fung, S. Horhota, 1978, Journal of pharmaceutical sciences.

Cellular interactions between L-arginine and asymmetric dimethylarginine: Transport and metabolism

Soyoung Shin, H. Fung, Subindra Kazi Thapa, 2017, PloS one.

Evaluation and development of gas chromatographic procedures for the determination of gamma-hydroxybutyric acid and gamma-butyrolactone in plasma.

J. Lettieri, H. Fung, 1978, Biochemical medicine.

Dose-dependent pharmacokinetics of laevodopa and its metabolites in the rat.

H. Fung, L. Cheng, L. K. Cheng, 1976, Xenobiotica; the fate of foreign compounds in biological systems.

Inactivation of hepatic enzymes by inhalant nitrite—In vivo and in vitro studies

H. Fung, Steven G. Turowski, Kate E. Jank, 2007, The AAPS Journal.

Simultaneous determination of nitroglycerin and dinitrate metabolites in metabolism studies using liquid chromatography-mass spectrometry with electrospray ionization.

H. Fung, Takashi Miyayama, P. Tsou, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Impact of mechanism-based enzyme inactivation on inhibitor potency: Implications for rational drug discovery

H.-L. Fung, T. S. Maurer, Tabrizi-Fard, 2000 .

Oral ethanol ingestion altered nifedipine pharmacokinetics in the rat: a preliminary study.

K. Boje, H. Fung, J. A. Dolce, 1984, Research communications in chemical pathology and pharmacology.

Haemodynamic effects of combined oral nifedipine and sublingual nitroglycerin in patients with chronic stable angina

J. Parker, K. Boje, H. Fung, 2004, European Journal of Clinical Pharmacology.

Pharmacokinetics of Organic Nitrates and Their Metabolites: Are They Relevant in Therapy?

H. Fung, 1987 .

Utilization of antidrug antibody fragments for the optimization of intraperitoneal drug therapy: studies using digoxin as a model drug.

H. Fung, J. Balthasar, 1994, The Journal of pharmacology and experimental therapeutics.

Cardiac output is an apparent determinant of nitroglycerin pharmacokinetics in rats.

H. Fung, S. Chong, A. Blei, 1986, The Journal of pharmacology and experimental therapeutics.

Gas chromatographic analysis of isomeric organic mononitrates in plasma.

H. Fung, T. Tzeng, 1991, Journal of chromatography.

Endothelial nitric oxide generating enzyme(s) in the bovine aorta: subcellular location and metabolic characterization.

K. Boje, H. Fung, Ho-Leung Fung, 1990, The Journal of pharmacology and experimental therapeutics.

Impact of mechanism-based enzyme inactivation on inhibitor potency: implications for rational drug discovery.

T. Maurer, H. Fung, M. Tabrizi-Fard, 2000, Journal of pharmaceutical sciences.

Factors affecting the kinetic assay of nitroglycerin in dosage forms.

C. Rhodes, S. K. Yap, H. Fung, 1975, American journal of hospital pharmacy.

Role of the liver in the disposition of intravenous nitroglycerin in the rat.

J. Gottstein, H. Fung, A. Blei, 1984, Biochemical pharmacology.

Pharmacokinetic/pharmacodynamic relationship of the duration of vasodilating action of organic mononitrates in rats.

H. Fung, T. Tzeng, 1992, Journal of Pharmacology and Experimental Therapeutics.

Chemical kinetics and drug stability

H. Fung, 1990 .

Pharmacokinetics of a model organic nitrite inhalant and its alcohol metabolite in rats.

H. Fung, W. Kielbasa, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Effects of L-cysteine, L-cysteine derivatives and ascorbic acid on lead excretion in rats.

H. Fung, E. McNiff, H. Woodfield, 1978, Research communications in chemical pathology and pharmacology.

Absorption of sodium gamma-hydroxybutyrate and its prodrug gamma-butyrolactone: relationship between in vitro transport and in vivo absorption.

H. Fung, C. Arena, 1980, Journal of pharmaceutical sciences.

Percutaneous butyrolactone absorption in rats.

J. Lettieri, H. Fung, Robert A. Bochner, 1979, Journal of pharmaceutical sciences.

Comparison of methods for analyzing kinetic data from mechanism-based enzyme inactivation: Application to nitric oxide synthase

T. Maurer, H. Fung, 2000, AAPS PharmSci.

Determination of nitric oxide-donor effects on tissue gene expression in vivo using low-density gene arrays.

D. Brazeau, H. Fung, D. Tran, 2005, Methods in enzymology.

Complexation of Nifedipine with Substituted Phenolic Ligands

K. Boje, H. Fung, Marion Sak, 1988, Pharmaceutical Research.

Intracellular L-arginine concentration does not determine NO production in endothelial cells: implications on the "L-arginine paradox".

Soyoung Shin, H. Fung, Srinidi Mohan, 2011, Biochemical and biophysical research communications.

High-affinity rabbit antibodies directed against methotrexate: production, purification, characterization, and pharmacokinetics in the rat.

H. Fung, J. Balthasar, 1995, Journal of pharmaceutical sciences.

Domestic dog health worsens with socio-economic deprivation of their home communities.

N. Gottdenker, A. Saldaña, J. Calzada, 2014, Acta tropica.

Preface to the special issue to honor Gerhard Levy and 50 years of PK/PD

W. Jusko, H. Fung, 2015, Journal of Pharmacokinetics and Pharmacodynamics.

Perspectives on the history and scientific contributions of Gerhard Levy

William J. Jusko, W. Jusko, H. Fung, 2015, Journal of Pharmacokinetics and Pharmacodynamics.

Estimation of nitric oxide synthase activity via liquid chromatography/tandem mass spectrometric assay determination of 15N3 -citrulline in biological samples.

Soyoung Shin, B. Shin, H. Fung, 2015, Rapid communications in mass spectrometry : RCM.

In vitro organic nitrate bioactivation to nitric oxide by recombinant aldehyde dehydrogenase 3A1.

H. Fung, Shun-hua Lin, Nathaniel A. Page, 2013, Nitric oxide : biology and chemistry.

Cellular mechanisms of nitrate action.

H. Fung, S. Chung, K. Hough, 1989, Zeitschrift fur Kardiologie.