Na Liu

发表

Allosteric Modulators of Protein-Protein Interactions (PPIs).

D. Ni, C. Sheng, Na Liu, 2019, Advances in experimental medicine and biology.

Divergent Cascade Construction of Skeletally Diverse “Privileged” Pyrazole‐Derived Molecular Architectures

Shengzheng Wang, Jian Li, Yongqiang Zhang, 2015 .

Enantioselective organocatalytic Michael addition of isorhodanines to α,β-unsaturated aldehydes.

Weiqi Wang, Yongqiang Zhang, Shanchao Wu, 2016, Organic & biomolecular chemistry.

Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents.

Shengzheng Wang, Jian Li, Guoqiang Dong, 2015, Journal of medicinal chemistry.

Identification of benzothiophene amides as potent inhibitors of human nicotinamide phosphoribosyltransferase.

Guoqiang Dong, Wannian Zhang, C. Sheng, 2016, Bioorganic & medicinal chemistry letters.

Role of Azole Drugs in Promoting Fungal Cell Autophagy Revealed by an NIR Fluorescence-Based Theranostic Probe.

C. Sheng, Na Liu, Yanhui Zhang, 2022, Analytical chemistry.

Discovery of Novel Multiacting Topoisomerase I/II and Histone Deacetylase Inhibitors.

Wei Chen, Guoqiang Dong, Zhenyuan Miao, 2015, ACS medicinal chemistry letters.

Design, synthesis and biological evaluation of E-ring modified evodiamine derivatives as novel antitumor agents

Shiping Zhu, Guoqiang Dong, Zhenyuan Miao, 2014 .

Small molecules for combating multidrug-resistant superbug Candida auris infections

C. Sheng, Na Liu, Wanzhen Yang, 2022, Acta pharmaceutica Sinica. B.

Identification of the scorpion venom-derived antimicrobial peptide Hp1404 as a new antimicrobial agent against carbapenem-resistant Acinetobacter baumannii.

Na Liu, Zongyun Chen, Xudong Luo, 2021, Microbial pathogenesis.

Discovery of simplified sampangine derivatives as novel fungal biofilm inhibitors.

Jian Li, Yuan-Ying Jiang, Wannian Zhang, 2018, European journal of medicinal chemistry.

Identification of pyrazolopyridine derivatives as novel spleen tyrosine kinase inhibitors

Guoqiang Dong, Wannian Zhang, C. Sheng, 2018, Archiv der Pharmazie.

From Antidiabetic to Antifungal: Discovery of Highly Potent Triazole–Thiazolidinedione Hybrids as Novel Antifungal Agents

Xiaomeng He, Shengzheng Wang, Yongqiang Zhang, 2014, ChemMedChem.

Discovery of highly potent triazoleantifungal agents with piperidine-oxadiazole side chains

Xiaomeng He, Yongqiang Zhang, Shanchao Wu, 2015 .

Discovery of Simplified Sampangine Derivatives with Potent Antifungal Activities against Cryptococcal Meningitis.

C. Sheng, Na Liu, Zhuang Li, 2019, ACS infectious diseases.

Discovery of Carboline Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcal Meningitis.

C. Sheng, Na Liu, Zhuang Li, 2019, Journal of medicinal chemistry.

Discovery of novel simplified isoxazole derivatives of sampangine as potent anti-cryptococcal agents.

C. Sheng, Na Liu, Zhuang Li, 2019, Bioorganic & medicinal chemistry.

Jumonji Histone Demethylase Inhibitor JIB-04 as a Broad-Spectrum Antifungal Agent.

C. Sheng, Na Liu, Yun Liu, 2022, ACS infectious diseases.

Targeting fungal virulence factor by small molecules: Structure-based discovery of novel secreted aspartic protease 2 (SAP2) inhibitors.

Shanchao Wu, Guoqiang Dong, C. Sheng, 2020, European journal of medicinal chemistry.

Tackling Fungal Resistance by Biofilm Inhibitors.

Shanchao Wu, Guoqiang Dong, C. Sheng, 2017, Journal of medicinal chemistry.

Identification of potent catalytic inhibitors of human DNA topoisomerase II by structure-based virtual screening.

Ying Sun, Shanchao Wu, Guoqiang Dong, 2018, MedChemComm.

Emerging New Targets for the Treatment of Resistant Fungal Infections.

Guoqiang Dong, C. Sheng, Na Liu, 2018, Journal of medicinal chemistry.

Novel carboline derivatives as potent antifungal lead compounds: design, synthesis, and biological evaluation.

Xiaomeng He, Shengzheng Wang, Jian Li, 2014, ACS medicinal chemistry letters.

Design, synthesis and evaluation of 4-substituted anthra[2,1-c][1,2,5]thiadiazole-6,11-dione derivatives as novel non-camptothecin topoisomerase I inhibitors.

Shanchao Wu, Guoqiang Dong, Wannian Zhang, 2017, Bioorganic & medicinal chemistry letters.

The discovery and characterization of a novel scaffold as a potent hepatitis C virus inhibitor.

Shiping Zhu, Xiaonan Zhang, Guoqiang Dong, 2016, Chemical communications.

Scaffold hopping of sampangine: discovery of potent antifungal lead compound against Aspergillus fumigatus and Cryptococcus neoformans.

Wei Chen, Guoqiang Dong, Zhenyuan Miao, 2014, Bioorganic & medicinal chemistry letters.

Strategies in the discovery of novel antifungal scaffolds.

Wannian Zhang, C. Sheng, Na Liu, 2016, Future medicinal chemistry.

Design, synthesis and antifungal activity of novel triazole derivatives containing substituted 1,2,3-triazole-piperdine side chains.

Shengzheng Wang, Guoqiang Dong, Zhenyuan Miao, 2014, European journal of medicinal chemistry.

Discovery of Novel Sertraline Derivatives as Potent Anti-Cryptococcus Agents.

Jian Li, C. Sheng, Na Liu, 2022, Journal of medicinal chemistry.

New triazole derivatives containing substituted 1,2,3-triazole side chains: Design, synthesis and antifungal activity

Wannian Zhang, C. Sheng, Na Liu, 2017 .

The discovery of novel antifungal scaffolds by structural simplification of the natural product sampangine.

Haiying He, Yuan-Ying Jiang, Guoqiang Dong, 2015, Chemical communications.

Discovery of Novel Fungal Lanosterol 14α-Demethylase (CYP51)/Histone Deacetylase (HDAC) Dual Inhibitors to Treat Azole-resistant Candidiasis.

C. Sheng, Na Liu, Zhuang Li, 2020, Journal of medicinal chemistry.

Imidazolone-amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: synthesis and biological evaluation.

Na Liu, Youjun Zhou, Ju Zhu, 2011, Bioorganic & medicinal chemistry.

BET-HDAC Dual Inhibitors for Combinational Treatment of Breast Cancer and Concurrent Candidiasis.

C. Sheng, Na Liu, Zhuang Li, 2023, Journal of medicinal chemistry.

Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles-resistant Candida albicans.

C. Sheng, Na Liu, Guiyan Han, 2021, European journal of medicinal chemistry.

Lanosterol 14α-demethylase (CYP51)/histone deacetylase (HDAC) dual inhibitors for treatment of Candida tropicalis and Cryptococcus neoformans infections.

C. Sheng, Defeng Xu, Na Liu, 2021, European journal of medicinal chemistry.

Novel Carboline Fungal Histone Deacetylase (HDAC) Inhibitors for Combinational Treatment of Azole-Resistant Candidiasis.

C. Sheng, Na Liu, Zhuang Li, 2020, Journal of medicinal chemistry.

Discovery of Janus Kinase 2 (JAK2) and Histone Deacetylase (HDAC) Dual Inhibitors as a Novel Strategy for the Combinational Treatment of Leukemia and Invasive Fungal Infections.

Guoqiang Dong, Wannian Zhang, C. Sheng, 2018, Journal of medicinal chemistry.

Novel spiropyrazolone antitumor scaffold with potent activity: Design, synthesis and structure-activity relationship.

Y. Li, Yongqiang Zhang, Shanchao Wu, 2016, European journal of medicinal chemistry.

Novel non-peptidic small molecule inhibitors of secreted aspartic protease 2 (SAP2) for the treatment of resistant fungal infections.

Guoqiang Dong, C. Sheng, Na Liu, 2018, Chemical communications.

Facile construction of pyrrolo[1,2-b]isoquinolin-10(5H)-ones via a redox-amination-aromatization-Friedel-Crafts acylation cascade reaction and discovery of novel topoisomerase inhibitors.

Shengzheng Wang, Jian Li, Shanchao Wu, 2016, Chemical communications.

Discovery of a new chemical scaffold for the treatment of superbug Candida auris infections

C. Sheng, Defeng Xu, Na Liu, 2023, Emerging microbes & infections.

Target- and prodrug-based design for fungal diseases and cancer-associated fungal infections.

C. Sheng, Na Liu, Zhuang Li, 2023, Advanced drug delivery reviews.

Discovery of Piperidol Derivatives for Combinational Treatment of Azole-Resistant Candidiasis.

Jian Li, C. Sheng, Na Liu, 2021, ACS infectious diseases.

Novel fluorescent probes of 10-hydroxyevodiamine: autophagy and apoptosis-inducing anticancer mechanisms

Shanchao Wu, Guoqiang Dong, Wannian Zhang, 2018, Acta pharmaceutica Sinica. B.

Discovery of BRD4-HDAC Dual Inhibitors with Improved Fungal Selectivity and Potent Synergistic Antifungal Activity against Fluconazole-Resistant Candida albicans.

Wei Wang, C. Sheng, Na Liu, 2023, Journal of medicinal chemistry.

Effects of Hsp90 Inhibitor Ganetespib on Inhibition of Azole-Resistant Candida albicans

C. Sheng, Na Liu, Xi Chen, 2021, Frontiers in Microbiology.

Drug Repurposing of Haloperidol: Discovery of New Benzocyclane Derivatives as Potent Antifungal Agents against Cryptococcosis and Candidiasis.

Jian Li, C. Sheng, Na Liu, 2019, ACS infectious diseases.

Novel carboline derivatives as potent antifungal lead compounds: design, synthesis, and biological evaluation.

Shengzheng Wang, Jian Li, Yongqiang Zhang, 2014, ACS Medicinal Chemistry Letters.

Novel Nitric Oxide Donor-Azole Conjugation Strategy for Efficient Treatment of Cryptococcus neoformans Infections.

C. Sheng, Na Liu, Zhangjian Huang, 2023, Journal of medicinal chemistry.

Controlling antifungal activity with light: Optical regulation of fungal ergosterol biosynthetic pathway with photo-responsive CYP51 inhibitors

C. Sheng, Na Liu, Wei Wang, 2023, Acta pharmaceutica Sinica. B.

Discovery of New Tricyclic Oxime Sampangine Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcosis and Candidiasis.

Na Liu, Zhuang Li, Wanzhen Yang, 2024, Journal of medicinal chemistry.

Discovery of Pyrazolone Carbothioamide Derivatives as Inhibitors of the Pdr1-KIX Interaction for Combinational Treatment of Azole-Resistant Candidiasis.

C. Sheng, Na Liu, Wanzhen Yang, 2023, Journal of medicinal chemistry.

The discovery and characterization of a novel scaffold as a potent hepatitis C virus inhibitor.

Shiping Zhu, Xiaonan Zhang, Guoqiang Dong, 2016, Chemical communications.