C. Cheung

发表

Disruption of protein–protein interactions: hot spot detection, structure-based virtual screening and in vitro testing for the anti-cancer drug target – survivin

H. Hsieh, M. Coumar, Sailu Sarvagalla, 2016 .

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Treat cancers by targeting survivin: just a dream or future reality?

M. Coumar, J. Kanwar, F. Tsai, 2013, Cancer treatment reviews.

Recent advances in anti-survivin treatments for cancer.

J. Chang, R. Kanwar, J. Kanwar, 2010, Current medicinal chemistry.

Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model

R. Kanwar, J. Kanwar, S. Krishnakumar, 2015, International journal of nanomedicine.

Proliferative and protective effects of SurR9-C84A on differentiated neural cells

S. Baratchi, R. Kanwar, J. Kanwar, 2010, Journal of Neuroimmunology.

Aging‐induced Akt activation involves in aging‐related pathologies and Aβ‐induced toxicity

C. Cheung, Yu-Ru Chen, Yu-Hsuan Li, 2019, Aging cell.

Aurora kinase inhibitor patents and agents in clinical testing: an update (2009 – 10)

H. Hsieh, M. Coumar, Jang-Yang Chang, 2011, Expert opinion on therapeutic patents.

Aurora kinase inhibitor patents and agents in clinical testing: an update (2011 – 2013)

M. Coumar, Sailu Sarvagalla, C. Cheung, 2014, Expert opinion on therapeutic patents.

YM155 down‐regulates survivin and XIAP, modulates autophagy and induces autophagy‐dependent DNA damage in breast cancer cells

J. Kanwar, C. Cheung, E. Leung, 2015, British journal of pharmacology.

Topical Ophthalmic Formulation of Trichostatin A and SurR9-C84A for Quick Recovery Post-alkali Burn of Corneal Haze

R. Kanwar, J. Kanwar, R. Sandhir, 2017, Front. Pharmacol..

E-Cadherin Aptamer-Conjugated delivery of Doxorubicin for targeted inhibition of prostate cancer cells

R. Kanwar, J. Kanwar, A. Verma, 2016 .

BIRC5/Survivin is a novel ATG12–ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells

M. Coumar, Pai-Sheng Chen, Sailu Sarvagalla, 2019, Autophagy.

Cancer Cells Acquire Mitotic Drug Resistance Properties Through Beta I-Tubulin Mutations and Alterations in the Expression of Beta-Tubulin Isotypes

H. Hsieh, Su-Ying Wu, Jian-Sung Wu, 2010, PloS one.

Targeting cathepsin S induces tumor cell autophagy via the EGFR-ERK signaling pathway.

W. Chang, Jang-Yang Chang, C. Kuo, 2012, Cancer letters.

Autophagy induced by cathepsin S inhibition induces early ROS production, oxidative DNA damage, and cell death via xanthine oxidase.

Jang-Yang Chang, C. Cheung, Kuo-Li Chen, 2013, Free radical biology & medicine.

The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells.

Sree Karani Kondapuram, M. Coumar, Yi-Chen Lin, 2020, Toxicology and applied pharmacology.

Clinical aspects for survivin: a crucial molecule for targeting drug-resistant cancers.

R. Kanwar, J. Kanwar, S. Krishnakumar, 2015, Drug discovery today.

Investigations of survivin: the past, present and future.

Huang-Hui Chen, Jang-Yang Chang, C. Cheung, 2011, Frontiers in bioscience.

Targeting Hsp90 with small molecule inhibitors induces the over-expression of the anti-apoptotic molecule, survivin, in human A549, HONE-1 and HT-29 cancer cells

J. Kanwar, Huang-Hui Chen, Jang-Yang Chang, 2010, Molecular Cancer.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

BPR1K653, a Novel Aurora Kinase Inhibitor, Exhibits Potent Anti-Proliferative Activity in MDR1 (P-gp170)-Mediated Multidrug-Resistant Cancer Cells

H. Hsieh, T. Lien, J. Hsu, 2011, PloS one.

Locked nucleic acid modified bi-specific aptamer-targeted nanoparticles carrying survivin antagonist towards effective colon cancer therapy

R. Kanwar, J. Kanwar, S. Krishnakumar, 2015 .

Anti-apoptotic proteins in the autophagic world: an update on functions of XIAP, Survivin, and BRUCE

C. Cheung, E. Leung, S. Cheng, 2020, Journal of Biomedical Science.

Survivin – biology and potential as a therapeutic target in oncology

F. Tsai, Jang-Yang Chang, C. Cheung, 2013, OncoTargets and therapy.

A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy

G. Krissansen, Xueying Sun, J. Kanwar, 2010, Cancer Cell International.

O6‐methylguanine DNA methyltransferase repairs platinum‐DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma

Huai-chih Chiang, T. Tsou, Chien-Feng Li, 2015, International journal of cancer.

An Updated Review of Smac Mimetics, LCL161, Birinapant, and GDC-0152 in Cancer Treatment

C. Cheung, Yung-Chieh Chang, 2020, Applied Sciences.

Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers

H. Hsieh, M. Coumar, Huang-Hui Chen, 2009, Molecular Cancer.

Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cells.

Chi-Hung Lin, Y. Kuo, T. Chao, 2010, Biochemical pharmacology.

Mutation of the PTCH1 gene predicts recurrence of breast cancer

Kuo-Ting Lee, Y. Kuo, Pai-Sheng Chen, 2019, Scientific Reports.

Cloning, expression, and purification of the recombinant pro-apoptotic dominant-negative survivin T34A-C84A protein in Escherichia coli.

M. Coumar, Shuying Wang, Sailu Sarvagalla, 2019, Protein expression and purification.

Aurora kinase inhibitors in preclinical and clinical testing.

H. Hsieh, M. Coumar, Jang-Yang Chang, 2009, Expert opinion on investigational drugs.

Aurora kinase inhibitors in preclinical and clinical testing

Mohane Selvaraj Coumar, Jang-Yang Chang, H. Hsieh, 2009, Expert opinion on investigational drugs.

The “Dark Side” of autophagy on the maintenance of genome stability: Does it really exist during excessive activation?

C. Cheung, S. Cheng, Tzu-Yu Lin, 2021, Journal of cellular physiology.

YM155 and BIRC5 downregulation induce genomic instability via autophagy-mediated ROS production and inhibition in DNA repair.

C. Cheung, E. Leung, S. Cheng, 2021, Pharmacological research.

Introduction to this special issue - ��Autophagy and Cancer: current biology and drug development��

C. Cheung, 2019, Journal of Cancer Metastasis and Treatment.

Survivin - caspase protein-protein interaction: Experimental evidence and computational investigations to decipher the hotspot residues for drug targeting

Sree Karani Kondapuram, M. Coumar, Sailu Sarvagalla, 2020 .

HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells

Kuo-Ting Lee, Y. Kuo, C. Chuang, 2017, Front. Pharmacol..

Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer

Xueying Sun, Qian Yang, C. Cheung, 2012, Investigational New Drugs.

Enhancement of non-homologous end joining DNA repair capacity confers cancer cells resistance to the novel selenophene compound, D-501036.

T. Tsou, Jang-Yang Chang, K. Chou, 2011, Cancer letters.

The Inducible Nitric-oxide Synthase (iNOS)/Src Axis Mediates Toll-like Receptor 3 Tyrosine 759 Phosphorylation and Enhances Its Signal Transduction, Leading to Interferon-β Synthesis in Macrophages*

M. Maa, Hui-Chen Chen, Guann-Yi Yu, 2014, The Journal of Biological Chemistry.

Challenges in Treating Estrogen Receptor-Positive Breast Cancer

C. Cheung, Shang-Hung Chen, 2018, Estrogen.

Tamoxifen Rechallenge Decreases Metastatic Potential but Increases Cell Viability and Clonogenicity in a Tamoxifen-Mediated Cytotoxicity-Resistant Subline of Human Breast MCF7 Cancer Cells

Y. Kuo, C. Cheung, Yung-Chieh Chang, 2020, Frontiers in Cell and Developmental Biology.

Dysfunction of different cellular degradation pathways contributes to specific β‐amyloid42‐induced pathologies

C. Cheung, Yu-Ru Chen, Tzu-Yu Lin, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Rac1 and Akt Exhibit Distinct Roles in Mediating Aβ-Induced Memory Damage and Learning Impairment

C. Cheung, Chia-Lin Wu, Hsueh-Cheng Chiang, 2021, Molecular Neurobiology.

Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study

C. Cheung, Ju-Ya Tsai, S. Cheng, 2016, OncoTargets and therapy.

Cancer Targeted Nanoparticles Specifically Induce Apoptosis in Cancer Cells and Spare Normal Cells

R. Kanwar, J. Kanwar, Ganesh Mahidhara, 2012 .

FTY720 in resistant human epidermal growth factor receptor 2-positive breast cancer

C. Cheung, C. Chiang, Wei-Pang Chung, 2022, Scientific reports.

Low expression of cytosolic NOTCH1 predicts poor prognosis of breast cancer patients.

Kuo-Ting Lee, Y. Kuo, Pai-Sheng Chen, 2022, American journal of cancer research.

Early Aβ42 Exposure Causes Learning Impairment in Later Life

C. Cheung, Hsueh-Cheng Chiang, Kuan‐Chung Cheng, 2022, Aging and disease.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

ML-IAP (Livin) And Human Cancers: A Recent Review

Xueying Sun, C. Cheung, J. R. Kanwar, 2011 .

Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells

Chien-Feng Li, Yi-Ching Wang, J. Kanwar, 2016, Front. Pharmacol..

Advances in Aurora kinase inhibitor patents

H. Hsieh, M. Coumar, Jang-Yang Chang, 2009, Expert opinion on therapeutic patents.