J. Barchi

发表

The neutral glycosphingolipid globotriaosylceramide promotes fusion mediated by a CD4-dependent CXCR4-utilizing HIV type 1 envelope glycoprotein.

R. Brady, R. Blumenthal, A. Puri, 1998, Proceedings of the National Academy of Sciences of the United States of America.

New paradigms in drug design and discovery.

Nouri Neamati, N. Neamati, J. Barchi, 2002, Current topics in medicinal chemistry.

S(3)E-E.COSY methods for the measurement of (19)F associated scalar and dipolar coupling constants.

B. Luy, J. Barchi, J. Marino, 2001, Journal of magnetic resonance.

Changes in DNA bending induced by restricting nucleotide ring pucker studied by weak alignment NMR spectroscopy.

Ad Bax, A. Bax, V. Marquez, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Solution NMR Conformational Analysis of the Potent Equilibrative Sensitive (ES) Nucleoside Transporter Inhibitor, S 6-(4-Nitrobenzyl)mercaptopurine Riboside (NBMPR)

J. Buolamwini, J. Barchi, 1997 .

Carbohydrate Nanotechnology and its Applications for the Treatment of Cancer

J. Barchi, Shailesh Ambre, Shailesh G. Ambre, 2015 .

Recognition of the Thomsen-Friedenreich Pancarcinoma Carbohydrate Antigen by a Lamprey Variable Lymphocyte Receptor*

M. Luo, R. Mariuzza, Z. Pancer, 2013, The Journal of Biological Chemistry.

Antitumor properties of 2(1H)-pyrimidinone riboside (zebularine) and its fluorinated analogues.

J. Plowman, V. Marquez, J. Driscoll, 1991, Journal of medicinal chemistry.

The decomposition of 1-(.beta.-D-ribofuranosyl)-1,2-dihydropyrimidin-2-one (zebularine) in alkali: mechanism and products

S. Musser, V. Marquez, J. Barchi, 1992 .

Improved synthesis of zebularine [1-(beta-D-ribofuranosyl)-dihydropyrimidin-2-one] nucleotides as inhibitors of human deoxycytidylate deaminase.

Z. Weinberg, V. Marquez, J. Barchi, 1995, Journal of enzyme inhibition.

Identification of a cytotoxin from Tolypothrix byssoidea as tubercidin

Richard E. Moore, J. Barchi, G. Patterson, 1983 .

Modulation of G protein-coupled adenosine receptors by strategically functionalized agonists and antagonists immobilized on gold nanoparticles

Steven M. Moss, K. Jacobson, Zhang-Guo Gao, 2013, Purinergic Signalling.

GalNAc-Tyrosine Is a Ligand of Plant Lectins, Antibodies, and Human and Murine Macrophage Galactose-Type Lectins.

J. Barchi, J. Gildersleeve, R. Gibadullin, 2017, ACS chemical biology.

Varied presentation of the Thomsen-Friedenreich disaccharide tumor-associated carbohydrate antigen on gold nanoparticles.

J. Barchi, Andreas Sundgren, 2008, Carbohydrate research.

Glycoside analogs of beta-galactosylceramide, a novel class of small molecule antiviral agents that inhibit HIV-1 entry.

H. Garg, R. Blumenthal, J. Fantini, 2008, Antiviral research.

A survey of place-exchange reaction for the preparation of water-soluble gold nanoparticles.

J. Barchi, Micah Maetani, Raymond P. Briñas, 2013, Journal of colloid and interface science.

Endothelial integrin α3β1 stabilizes carbohydrate-mediated tumor/endothelial cell adhesion and induces macromolecular signaling complex formation at the endothelial cell membrane

K. Pienta, S. Barnes, J. Barchi, 2014, Oncotarget.

Synthesis and cell-selective antitumor properties of amino acid conjugated tumor-associated carbohydrate antigen-coated gold nanoparticles.

Scott H. Medina, Souvik Biswas, J. Barchi, 2015, Carbohydrate research.

Mucin‐Type Glycopeptide Structure in Solution: Past, Present, and Future

J. Barchi, 2013, Biopolymers.

Glycoamino Acid Analogues of the Thomsen–Friedenreich Tumor-Associated Carbohydrate Antigen: Synthesis and Evaluation of Novel Antiproliferative Factor Glycopeptides

M. Siddiqui, J. Barchi, S. Keay, 2017, ACS omega.

Glycosylation affects both the three-dimensional structure and antibody binding properties of the HIV-1IIIB GP120 peptide RP135.

P. Roller, F. Lung, X. Huang, 1997, Biochemistry.

Using conformationally locked nucleosides to calibrate the anomeric effect: Implications for glycosyl bond stability.

Kristie M. Adams, J. Deschamps, H. Moon, 2010, Tetrahedron.

Glyco-Nanoparticles as Platforms for Antitumor Therapeutic Strategies

J. Barchi, 2011 .

Carbohydrate-Functionalized Nanomaterials : Synthesis , Characterization and Biorecognition

J. Barchi, 2015 .

Biophysical studies of DNA modified with conformationally constrained nucleotides: comparison of 2′-exo (north) and 3′-exo (south) ‘locked’ templates

V. Marquez, Que N. Van, J. Barchi, 2007, Nucleic acids research.

Toxins from cyanophytes belonging to the scytonemataceae

Richard E. Moore, S. Furusawa, J. Barchi, 1986 .

Acutiphycin and 20,21-didehydroacutiphycin, new antineoplastic agents from the cyanophyte Oscillatoria acutissima

Richard E. Moore, J. Barchi, G. Patterson, 1984 .

LESSONS FROM THE PSEUDOROTATIONAL CYCLE : CONFORMATIONALLY RIGID AZT CARBOCYCLIC NUCLEOSIDES AND THEIR INTERACTION WITH REVERSE TRANSCRIPTASE

C. George, H. Mitsuya, V. Marquez, 1998 .

Isolipoic acid-linked gold nanoparticles bearing the thomsen friedenreich tumor-associated carbohydrate antigen: Stability and in vitro studies

J. Barchi, U. Mondal, 2022, Frontiers in Chemistry.

Formation of Short, Stable Helices in Aqueous Solution by β-Amino Acid Hexamers

S. Durell, S. Gellman, J. Barchi, 1999 .

Adenosine deaminase prefers a distinct sugar ring conformation for binding and catalysis: kinetic and structural studies.

M. Nicklaus, L. Anderson, V. Marquez, 2000, Biochemistry.

High Affinity Grb2 SH2 Domain-Binding Macrocycles Derived from Ring-Closing Methathesis of Alkenylglyicne Residues with β-Vinyl Phosphotyrosyl Mimetics

R. Fisher, Fa Liu, T. Burke, 2006 .

Hydrolytic Reactivity Trends among Potential Prodrugs of the O2-Glycosylated Diazeniumdiolate Family. Targeting Nitric Oxide to Macrophages for Antileishmanial Activity

K. M. Davies, J. Deschamps, J. Saavedra, 2008, Journal of medicinal chemistry.

Emerging roles of carbohydrates and glycomimetics in anticancer drug design.

J. Barchi, 2000, Current pharmaceutical design.

Conformational Studies and Anti-HIV Activity of Mono- and Difluorodideoxy Nucleosides

M. Nicklaus, V. Marquez, J. Barchi, 1993 .

A diastereoselective synthesis of (S,S)-α-fluoro-2,2-dimethyl-1,3-dioxolane-4-propanoic acid methyl ester, a key intermediate for the preparation of anti-HIV effective fluorodideoxynucleosides

V. Marquez, M. Siddiqui, J. Driscoll, 1994 .

Residue-based control of helix shape in β-peptide oligomers

Douglas R. Powell, Joseph J. Barchi, Samuel H. Gellman, 1997, Nature.

Conformationally constrained phosphotyrosyl mimetics designed as monomeric Src homology 2 domain inhibitors.

S. Shoelson, T. Burke, J. Barchi, 1995, Journal of medicinal chemistry.

Conformationally locked nucleoside analogues. Synthesis of dideoxycarbocyclic nucleoside analogues structurally related to neplanocin C.

H. Mitsuya, M. Nicklaus, V. Marquez, 1994, Journal of medicinal chemistry.

Mining the NCI antiviral compounds for HIV-1 integrase inhibitors.

Y. Pommier, R. Dayam, N. Neamati, 2006, Bioorganic & medicinal chemistry.

Avermectin chemistry. 2. A secure and flawless strategy for the final synthetic stages

J. Barchi, R. Faghih, B. Fraser-Reid, 1988 .

Avermectin chemistry: problems of conjugation, deconjugation, and epimerization

J. Barchi, H. Wolleb, R. Faghih, 1987 .

Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic.

Marc C Nicklaus, Shinya Oishi, Robert J Fisher, 2005, Bioorganic & medicinal chemistry.

Synthesis of gold nanoparticles bearing the Thomsen–Friedenreich disaccharide: a new multivalent presentation of an important tumor antigen

S. Svarovsky, J. Barchi, Z. Székely, 2005 .

The “β-Fluorine Effect” in the Non-Metal Hydride Radical Deoxygenation of Fluorine-Containing Nucleoside Xanthates

V. Marquez, M. Siddiqui, J. Driscoll, 2000, Nucleosides, nucleotides & nucleic acids.

Synthesis of cyclopropane-fused dideoxycarbocyclic nucleosides structurally related to neplanocin C

M. Nicklaus, V. Marquez, J. Barchi, 1993 .

Facile photochemical synthesis of mixed siloxyacetal glycosides as potential pH-sensitized prodrugs for selective treatment of solid tumors.

S. Svarovsky, M. Taraban, J. Barchi, 2004, Organic & biomolecular chemistry.

Residue-based control of helix shape in beta-peptide oligomers.

S. Gellman, D. Powell, X. Huang, 1997, Nature.

Experimental and Chemoinformatics Study of Tautomerism in a Database of Commercially Available Screening Samples

Marc C. Nicklaus, Laura Guasch, Joseph J. Barchi, 2016, J. Chem. Inf. Model..

Structural comparison of a 15 residue peptide from the V3 loop of HIV‐1IIIb and an O‐glycosylated analogue

J. Berzofsky, J. Barchi, X. Huang, 1996, FEBS letters.

ZEBULARINE: A UNIQUE MOLECULE FOR AN EPIGENETICALLY BASED STRATEGY IN CANCER CHEMOTHERAPY. THE MAGIC OF ITS CHEMISTRY AND BIOLOGY

Peter A. Jones, V. Marquez, C. Yoo, 2005, Nucleosides, nucleotides & nucleic acids.

Inhibition of Cytidine Deaminase by Derivatives of 1-(β-D-Ribofuranosyl)-Dihydropyrimidin-2-One (Zebularine)

V. Marquez, J. Barchi, A. Haces, 1992 .

Use of borate complexation in assigning relative stereochemistry of acyclic polyhydroxylated compounds

Richard E. Moore, J. Barchi, Giovanni Bartolin, 1985 .

Stable Gold-Nanoparticle-Based Vaccine for the Targeted Delivery of Tumor-Associated Glycopeptide Antigens

J. Barchi, Kevin R. Trabbic, Kristopher A. Kleski, 2021, ACS Bio & Med Chem Au.

A Stable Nano-Vaccine for the Targeted Delivery of Tumor-Associated Glycopeptide Antigens

J. Barchi, Kevin R. Trabbic, Kristopher A. Kleski, 2021, bioRxiv.

Glycoconjugate Nanoparticle-Based Systems in Cancer Immunotherapy: Novel Designs and Recent Updates

J. Barchi, 2022, Frontiers in Immunology.

Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines.

H. Mitsuya, J. Roth, T. Shirasaka, 1992, Journal of medicinal chemistry.

HIV-1 REVERSE TRANSCRIPTASE CAN DISCRIMINATE BETWEEN TWO CONFORMATIONALLY LOCKED CARBOCYCLIC AZT TRIPHOSPHATE ANALOGUES

Victor E. Marquez, Joseph J. Barchi, Clifford George, 1998 .

Conformationally constrained analogues of diacylglycerol (DAG). Part 19: Asymmetric syntheses of (3R)- and (3S)-3-hydroxy-4,4-disubstituted heptono-1,4-lactones as protein kinase C (PK-C) ligands with increased hydrophilicity

P. Blumberg, V. Marquez, K. Nacro, 2002 .

A simple approach to 1′,1′a-methano carbocyclic thymidine

V. Marquez, J. Barchi, A. Ezzitouni, 1995 .

Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker.

Marc C Nicklaus, M. Nicklaus, V. Marquez, 2004, Journal of the American Chemical Society.

Chemistry and Anti‐HIV Properties of 2′‐Fluoro‐2′,3′‐ dideoxyarabinofuranosylpyrimidines.

H. Mitsuya, J. Roth, T. Shirasaka, 1992 .

Understanding the effects of carbocyclic sugars constrained to north and south conformations on RNA nanodesign.

B. Shapiro, Taejin Kim, V. Marquez, 2011, Journal of molecular graphics & modelling.

The Controlled Stereospecific Reduction of Cyclopentenyl Cytosine (CPE-C) to Carbodine and Isocarbodine

V. Marquez, P. Russ, J. Barchi, 1992 .

Design and synthesis of multifunctional gold nanoparticles bearing tumor-associated glycopeptide antigens as potential cancer vaccines.

J. Barchi, Wei Deng, K. Rittenhouse-Olson, 2012, Bioconjugate chemistry.

Interactions of conformationally biased north and south 2'-fluoro-2', 3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase.

M C Nicklaus, S. Sarafianos, H. Mitsuya, 2000, Biochemistry.

A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude.

Jan Balzarini, Stephen H Hughes, Clifford George, 2003, Journal of medicinal chemistry.

A Simple Approach to 1′,1′a‐Methano Carbocyclic Thymidine.

V. Marquez, J. Barchi, A. Ezzitouni, 1995 .

Conformational analysis of the complete series of 2' and 3' monofluorinated dideoxyuridines.

L. Jeong, V. Marquez, J. Barchi, 1997, Journal of biochemical and biophysical methods.

The effect of two antipodal fluorine-induced sugar puckers on the conformation and stability of the Dickerson-Drew dodecamer duplex [d(CGCGAATTCGCG)]2.

V. Marquez, X. Huang, J. Barchi, 1998, Nucleic acids research.

Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs.

H. Mitsuya, T. Shirasaka, V. Marquez, 1991, Journal of medicinal chemistry.

Comprehensive structural studies of 2',3'-difluorinated nucleosides: comparison of theory, solution, and solid state.

C. George, M. Nicklaus, V. Marquez, 2008, Journal of the American Chemical Society.

Enhanced epimerization of glycosylated amino acids during solid-phase peptide synthesis.

Kristie M. Adams, J. Barchi, Saddam M Muthana, 2012, Journal of the American Chemical Society.

Synthesis and characterization of oligonucleotides containing conformationally constrained bicyclo[3.1.0]hexane pseudosugar analogs.

M. Manoharan, M. Maier, V. Marquez, 2004, Nucleic acids research.

Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics.

A. Wlodawer, S. Smith‐Gill, Mi Li, 2012, Biochemistry.

A more expedient approach to the synthesis of anti-HIV-active 2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl nucleosides

R. Wysocki, V. Marquez, M. Siddiqui, 1991 .

An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide.

Thomas P Conrads, Timothy D Veenstra, Zoltan Szekely, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Diazeniumdiolate ions as leaving groups in anomeric displacement reactions: a protection-deprotection strategy for ionic diazeniumdiolates.

K. M. Davies, M. Meyerhoff, J. Saavedra, 2005, Journal of the American Chemical Society.

Identification of HIV-1 integrase inhibitors via three-dimensional database searching using ASV and HIV-1 integrases as targets.

Alexander D. MacKerell, M C Nicklaus, Y. Pommier, 2000, Bioorganic & medicinal chemistry.

Sugar-binding proteins from fish: selection of high affinity "lambodies" that recognize biomedically relevant glycans.

R. Mariuzza, Mark Z. Ma, Z. Pancer, 2013, ACS chemical biology.

Absolute stereochemistry of palytoxin

J. Dadok, G. Bartolini, A. Bothner‐By, 1982 .

Identification of Substrate Binding Site of Cyclin-dependent Kinase 5*

P. J. Steinbach, H. Pant, N. Amin, 1999, The Journal of Biological Chemistry.

The effect of a methyl group on structure and function: Serine vs. threonine glycosylation and phosphorylation

J. Barchi, Caitlin N. Strain, 2023, Frontiers in Molecular Biosciences.

Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase

A. Monks, K. Krohn, V. Marquez, 1994, International journal of cancer.

A Tumor-Selective Monoclonal Antibody from Immunization with a Tumor-Associated Mucin Glycopeptide

J. Barchi, J. Gildersleeve, E. Edmondson, 2019, Scientific Reports.

Divergent behavior of glycosylated threonine and serine derivatives in solid phase peptide synthesis.

J. Barchi, Saddam M Muthana, J. Gildersleeve, 2012, Organic letters.

Inter-helical interactions in the leucine zipper coiled coil dimer: pH and salt dependence of coupling energy between charged amino acids.

C. Vinson, J. Barchi, D Krylov, 1998, Journal of molecular biology.

Investigation of the backbone dynamics of the igg‐binding domain of streptococcal protein g by heteronuclear two‐dimensional 1H‐15N nuclear magnetic resonance spectroscopy

A. Gronenborn, G. Clore, B. Grasberger, 1994, Protein science : a publication of the Protein Society.

Synthesis and structure activity studies of phosphatase resistant SH2 domain inhibiting peptides: D-amino acid effects

S. Shoelson, P. Roller, T. Burke, 1995 .

359: Complete Characterization of an Antiproliferative Factor from Bladder Epithelial Cells of Interstitial Cystitis Patients

T. Veenstra, T. Conrads, C. Michejda, 2004 .

Structure-activity relationship studies for the peptide portion of the bladder epithelial cell antiproliferative factor from interstitial cystitis patients.

C. Michejda, J. Barchi, Piotr Kaczmarek, 2008, Journal of medicinal chemistry.

Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure

A. Ferré-D’Amaré, J. Barchi, T. Numata, 2019, Nature Communications.

Design and synthesis of a new tyrosine analog having χ 1 and χ 2 angles constrained to values observed for an SH2 domain-bound phosphotyrosyl residue

T. Burke, Z. Yao, J. Barchi, 2002 .

Conformational analysis of cyclic hexapeptides designed as constrained ligands for the SH2 domain of the p85 subunit of phosphatidylinositol-3-OH kinase.

P. Roller, T. Burke, A. Otaka, 1996, Biopolymers.

Norleucine as a replacement for methionine in phosphatase-resistant linear and cyclic peptides which bind to p85 SH2 domains

S. Shoelson, P. Roller, T. Burke, 1994 .

Highly efficient preparation of tumor antigen-containing glycopeptide building blocks from novel pentenyl glycosides.

S. Svarovsky, J. Barchi, 2003, Carbohydrate research.

Introduction to Comprehensive Glycoscience: The Good, the Better and What's to Come

J. Barchi, 2021 .

Normalization of Proliferation and Tight Junction Formation in Bladder Epithelial Cells from Patients with Interstitial Cystitis/Painful Bladder Syndrome by d‐Proline and d‐Pipecolic Acid Derivatives of Antiproliferative Factor

Zoltan Szekely, C. Michejda, J. Barchi, 2011, Chemical biology & drug design.

ENGINEERING DNA TOPOLOGY WITH LOCKED NUCLEOSIDES: A STRUCTURAL STUDY

A. Bax, Justin Wu, V. Marquez, 2005, Nucleosides, nucleotides & nucleic acids.

The effect of a novel frizzled 8-related antiproliferative factor on in vitro carcinoma and melanoma cell proliferation and invasion

J. Barchi, Piotr Kaczmarek, Chen-Ou Zhang, 2012, Investigational New Drugs.

Structure of malyngamide C

J. Barchi, J. S. Mynderse, M. Kuniyoshi, 1985 .

Reaction of geldanamycin and C17-substituted analogues with glutathione: product identifications and pharmacological implications.

P. Steeg, J. Strong, J. Barchi, 2006, Chemical research in toxicology.

Stable Gold-Nanoparticle-Based Vaccine for the Targeted Delivery of Tumor-Associated Glycopeptide Antigens

J. Barchi, Kevin R. Trabbic, Kristopher A. Kleski, 2021, ACS bio & med chem Au.

Peptide Structure Stabilization by Membrane Anchoring and its General Applicability to the Development of Potent Cell‐Permeable Inhibitors

Kristie M. Adams, V. Gaponenko, S. Tarasov, 2011, Chembiochem : a European journal of chemical biology.

Conformationally constrained analogs of diacylglycerol. Interaction of .gamma.-lactones with the phorbol ester receptor of protein kinase C

G. Milne, M. Kazanietz, P. Blumberg, 1992 .

Conformationally Constrained Analogues of Diacylglycerol. Interaction of γ-Lactones with the Phorbol Ester Receptor of Protein Kinase C.

G. Milne, M. Kazanietz, P. Blumberg, 2010 .

Fluorine Labeling of the HyHEL 10 Antibody A ff ects Antigen Binding and Dynamics

A. Wlodawer, S. Smith‐Gill, Mi Li, 2012 .

Glycosylation of the active sequence ser-ile-lys-val-ala-val from the α1 chain of laminin reduces tumor cell attachment activity

A. Otaka, M. Nomizu, Yoshihiko Yamada, 1995 .

Modulation of G protein-coupled adenosine receptors by strategically functionalized agonists and antagonists immobilized on gold nanoparticles

Steven M. Moss, K. Jacobson, Zhang-Guo Gao, 2013, Purinergic Signalling.

Studies on the mechanism of action of 1-beta-D-arabinofuranosyl-5-azacytosine (fazarabine) in mammalian lymphoblasts.

K. Paull, J. Barchi, D. Cooney, 1996, Journal of experimental therapeutics & oncology.

Site-specific phosphorylation of Lys-Ser-Pro repeat peptides from neurofilament H by cyclin-dependent kinase 5: structural basis for substrate recognition.

H. Pant, N. Amin, X. Huang, 1998, Biochemistry.

Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure

A. Ferré-D’Amaré, J. Barchi, T. Numata, 2019, Nature Communications.

A Small-Molecule Microarray Approach for the Identification of E2 Enzyme Inhibitors in Ubiquitin-Like Conjugation Pathways

W. M. Hewitt, J. Tropea, D. Waugh, 2017, SLAS discovery : advancing life sciences R & D.

GalNAc-Tyrosine Is a Ligand of Plant Lectins, Antibodies, and Human and Murine Macrophage Galactose-Type Lectins.

J. Barchi, J. Gildersleeve, R. Gibadullin, 2017, ACS chemical biology.

Varied presentation of the Thomsen-Friedenreich disaccharide tumor-associated carbohydrate antigen on gold nanoparticles.

J. Barchi, Andreas Sundgren, 2008, Carbohydrate research.

Divergent behavior of glycosylated threonine and serine derivatives in solid phase peptide synthesis.

J. Barchi, Saddam M Muthana, J. Gildersleeve, 2012, Organic letters.

Conformational analysis of an α3β1 integrin-binding peptide from thrombospondin-1: Implications for antiangiogenic drug design

J. Furrer, D. Roberts, B. Luy, 2006 .

Structure-Activity Studies on Antiproliferative Factor (APF) Glycooctapeptide Derivatives.

Kristie M. Adams, C. Michejda, J. Barchi, 2010, ACS medicinal chemistry letters.