J. Quintana

发表

Undiscovered Roles for Transthyretin: From a Transporter Protein to a New Therapeutic Target for Alzheimer’s Disease

Ellen Y. Cotrina, J. Llop, Tiago Gião, 2020, International journal of molecular sciences.

Retrospective Mapping of SAR Data for TTR Protein in Chemico‐Biological Space Using Ligand Efficiency Indices as a Guide to Drug Discovery Strategies

C. Abad-Zapatero, G. Valencia, M. Pinto, 2011, Molecular informatics.

Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD

Ellen Y. Cotrina, J. Jiménez-Barbero, J. Llop, 2019, Scientific Reports.

Oral treatment with iododiflunisal delays beta amyloid plaque formation in a transgenic mouse model of Alzheimer Disease: a Longitudinal in vivo molecular imaging study

Ellen Y. Cotrina, Tiago Gião, J. Quintana, 2020 .

The Chembiobank project: building annotated molecular libraries for drug discovery

Fernando Albericio, Ferran Sanz, Jordi Mestres, 2009 .

Synthesis, pharmacological evaluation and molecular docking of pyranopyrazole-linked 1,4-dihydropyridines as potent positive inotropes

J. Mestres, M. Loza, J. Brea, 2017, Molecular Diversity.

Binding of common organic UV-filters to the thyroid hormone transport protein transthyretin using in vitro and in silico studies: Potential implications in health.

Ellen Y. Cotrina, M. Díaz-Cruz, X. Biarnés, 2022, Environmental research.

Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.

Ellen Y. Cotrina, J. Llop, G. Valencia, 2017, Journal of medicinal chemistry.

Design of a General‐Purpose European Compound Screening Library for EU‐OPENSCREEN

Dragos Horvath, Gilles Marcou, Jordi Mestres, 2014, ChemMedChem.

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

Ursula Bilitewski, Aigars Jirgensons, Jordi Mestres, 2019, SLAS discovery : advancing life sciences R & D.

Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study.

Ellen Y. Cotrina, J. Llop, Tiago Gião, 2020, Journal of Alzheimer's disease : JAD.

Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer’s Disease Drug Discovery

Ellen Y. Cotrina, J. Llop, G. Valencia, 2020, Journal of medicinal chemistry.

Optimization of kinetic stabilizers of tetrameric transthyretin: A prospective ligand efficiency-guided approach.

Ellen Y. Cotrina, C. Abad-Zapatero, J. Quintana, 2020, Bioorganic & medicinal chemistry.

An assay for screening potential drug candidates for Alzheimer's disease that act as chaperones of the Transthyretin and Amyloid-ß peptides interaction.

Ellen Y. Cotrina, J. Llop, J. Quintana, 2020, Chemistry.

Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease.

Ellen Y. Cotrina, M. Busquets, J. Llop, 2021, European journal of medicinal chemistry.

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

J. Mestres, S. Krauss, J. Brea, 2019, SLAS discovery : advancing life sciences R & D.

Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer

Ellen Y. Cotrina, J. Llop, L. Gales, 2020, International journal of molecular sciences.

Modulation of the fibrillogenesis inhibition properties of two transthyretin ligands by halogenation.

Ellen Y. Cotrina, G. Valencia, M. Pinto, 2013, Journal of medicinal chemistry.