G. Nordvall

发表

Atropisomeric derivatives of 2',6'-disubstituted (R)-11-phenylaporphine: selective serotonin 5-HT(7) receptor antagonists.

U. Hacksell, T. Linnanen, M. Brisander, 2001, Journal of medicinal chemistry.

Derivatives of cis-2-amino-8-hydroxy-1-methyltetralin: mixed 5-HT1A-receptor agonists and dopamine D2-receptor antagonists.

T. Lewander, U. Hacksell, N. Mohell, 1995, Journal of medicinal chemistry.

Identification of Novel Positive Allosteric Modulators of Neurotrophin Receptors for the Treatment of Cognitive Dysfunction

B. Winblad, M. Eriksdotter, G. Nordvall, 2021, Cells.

Chapter Five - Stimulating Neurotrophin Receptors in the Treatment of Neurodegenerative Disorders

G. Nordvall, P. Forsell, 2014 .

Molecular basis for the binding of 2-aminotetralins to human dopamine D2A and D3 receptors.

U. Hacksell, N. Mohell, G. Nordvall, 1994, Molecular pharmacology.

Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

David S. Park, D. Ferreira, J. Ruas, 2021, BMC Biology.

Substituted 7-amino-5-thio-thiazolo[4,5-d]pyrimidines as potent and selective antagonists of the fractalkine receptor (CX3CR1).

V. Ivanov, L. Vares, P. Svensson, 2013, Journal of medicinal chemistry.

Interactions of ligands with active and inactive conformations of the dopamine D2 receptor.

U. Hacksell, N. Mohell, G. Nordvall, 1998, European journal of pharmacology.

γ‐Secretase modulators show selectivity for γ‐secretase–mediated amyloid precursor protein intramembrane processing

K. Blennow, B. Winblad, H. Zetterberg, 2021, Journal of cellular and molecular medicine.

Neurotrophin-targeted therapeutics: a gateway to cognition and more?

G. Nordvall, J. Sandin, Pontus Forsell, 2022, Drug discovery today.

5‐Oxygenated N‐Alkyl‐and N,N‐Dialkyl‐2‐amino‐1‐methyltetralins. Effects of Structure and Stereochemistry on Dopamine‐D2‐receptor Affinity

U. Hacksell, G. Nordvall, A. Johansson, 1991, The Journal of pharmacy and pharmacology.

P.0229 Characterization of positive allosteric modulators of trkb for the treatment of depression

G. Nordvall, J. Sandin, M. Backlund, 2021, European Neuropsychopharmacology.

Exploration and pharmacokinetic profiling of phenylalanine based carbamates as novel substance p 1-7 analogues.

P. Artursson, A. Sandström, M. Hallberg, 2014, ACS medicinal chemistry letters.

11-substituted (R)-aporphines: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions.

S. Hjorth, J. Jansen, T. Linnanen, 1996, Journal of medicinal chemistry.

(R)-11-hydroxy- and (R)-11-hydroxy-10-methylaporphine: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions.

S. Hjorth, U. Hacksell, S. Sundell, 1995, Journal of medicinal chemistry.

Novel 2-aminotetralin and 3-aminochroman derivatives as selective serotonin 5-HT7 receptor agonists and antagonists.

N. Mohell, S. Rosqvist, G. Nordvall, 2004, Journal of medicinal chemistry.

Small constrained SP1–7 analogs bind to a unique site and promote anti-allodynic effects following systemic injection in mice

H. Watanabe, E. Brolin, F. Nyberg, 2015, Neuroscience.

3-Heteroaryl-substituted quinuclidin-3-ol and quinuclidin-2-ene derivatives as muscarinic antagonists. Synthesis and structure-activity relationships.

U. Hacksell, G. Nordvall, S. Sundquist, 1995, Journal of medicinal chemistry.

Analogues of the muscarinic agent 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane]: synthesis and pharmacology.

U. Hacksell, A. Gogoll, G. Nordvall, 1992, Journal of medicinal chemistry.

Quinuclidin-2-ene-based muscarinic antagonists.

U. Hacksell, G. Nordvall, S. Sundquist, 1995, Life sciences.

The battle of Alzheimer’s Disease – the beginning of the future Unleashing the potential of academic discoveries

B. Winblad, G. Johansson, S. Svensson, 2014, Front. Pharmacol..

Identification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neurons

M. Eriksdotter, E. Sundström, G. Nordvall, 2019, The European journal of neuroscience.

Mutagenesis and ligand modification studies on galanin binding to its GTP-binding-protein-coupled receptor GalR1.

T. Bártfai, Ű. Langel, A. Juréus, 1997, European journal of biochemistry.

Molecular Design Using the Minireceptor Concept

James P. Snyder, Konrad F. Koehler, Johanna M. Jansen, 1997, J. Chem. Inf. Comput. Sci..

Binding-site modeling of the muscarinic m1 receptor: a combination of homology-based and indirect approaches.

U. Hacksell, G. Nordvall, U Hacksell, 1993, Journal of medicinal chemistry.

Synthesis and pharmacology of the enantiomers of UH301: opposing interactions with 5-HT1A receptors.

T. Lewander, U. Hacksell, G. Nordvall, 1996, Chirality.

Delineation of the peptide binding site of the human galanin receptor.

T. Bártfai, U. Kahl, G. Nordvall, 1996, The EMBO journal.

Mutagenesis Study on Human Galanin Receptor GalR1 Reveals Domains Involved in Ligand Binding a

T. Bártfai, Ü. Langel, A. Juréus, 1998, Annals of the New York Academy of Sciences.

Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease

H. Lassmann, T. Olsson, G. Nordvall, 2003, Journal of Neuroimmunology.

Mutagenesis of the human 5-HT1B receptor: differences from the closely related 5-HT1A receptor and the role of residue F331 in signal transduction.

D. Larhammar, G. Nordvall, C. Grånäs, 1998, Journal of receptor and signal transduction research.

Site-directed mutagenesis of the human 5-HT1B receptor.

D. Larhammar, G. Nordvall, C. Grånäs, 1998, European journal of pharmacology.

Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

David S. Park, D. Ferreira, J. Ruas, 2021, BMC biology.

Adenosine A1 receptor and ligand molecular modeling

K. Jacobson, A. IJzerman, N. Peet, 1993 .

A basic peptide within the juxtamembrane region is required for EGF receptor dimerization.

O. Hermanson, I. Lundström, S. Aifa, 2005, Experimental cell research.

Synthesis of novel 5-substituted 3-amino-3,4-dihydro-2H-1-benzopyran derivatives and their interactions with the 5-HT1A receptor.

C. Ahlgren, E. Jerning, N. Mohell, 2000, Journal of medicinal chemistry.

10-substituted 11-oxygenated (R)-aporphines: synthesis, pharmacology, and modeling of 5-HT1A receptor interactions.

S. Hjorth, J. Jansen, L. Unelius, 1996, Journal of medicinal chemistry.

3-(2-Benzofuranyl)quinuclidin-2-ene derivatives: novel muscarinic antagonists.

U. Hacksell, G. Nordvall, S. Sundquist, 1996, Journal of medicinal chemistry.

Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer’s Disease

G. Nordvall, J. Sandin, M. Backlund, 2023, International journal of molecular sciences.

Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling – a potential therapeutic concept?

M. Lindskog, G. Nordvall, J. Sandin, 2023, Psychopharmacology.

Substituted 7-amino-5-thio-thiazolo[4,5-d]pyrimidines as potent and selective antagonists of the fractalkine receptor (CX3CR1).

V. Ivanov, L. Vares, E. Jerning, 2013, Journal of medicinal chemistry.

Creation of Novel Cores for β-Secretase (BACE-1) Inhibitors: A Multiparameter Lead Generation Strategy.

M. Svensson, B. Swahn, K. Kolmodin, 2014, ACS medicinal chemistry letters.