Dennis J. Selkoe

发表

D. Selkoe, Dennis J. Selkoe, 2012, Science.

Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease

Nobutaka Hattori, Yoshikuni Mizuno, Matthew P. Frosch, 2001, Science.

Environmental Novelty Activates β2-Adrenergic Signaling to Prevent the Impairment of Hippocampal LTP by Aβ Oligomers

Shaomin Li, Ting Yang, Shaomin Li, 2013, Neuron.

Altered Fatty Acid Composition of Dopaminergic Neurons Expressing α-Synuclein and Human Brains with α-Synucleinopathies*

Charles N. Serhan, D. Selkoe, C. Serhan, 2003, Journal of Biological Chemistry.

Alterations in Memory Networks in Mild Cognitive Impairment and Alzheimer's Disease: An Independent Component Analysis

Vince D. Calhoun, Bradford C. Dickerson, Reisa A. Sperling, 2006, The Journal of Neuroscience.

Early network dysfunction in Alzheimer's disease

D. Selkoe, Dennis J. Selkoe, 2019, Science.

A mathematical model of the impact of novel treatments on the Aβ burden in the Alzheimer’s brain, CSF and plasma

Lawrence M. Wein, David L. Craft, L. Wein, 2015, Bulletin of mathematical biology.

Presenilin: Running with Scissors in the Membrane

Michael S. Wolfe, D. Selkoe, M. Wolfe, 2007, Cell.

Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo

Matthew P. Frosch, Rudolph E. Tanzi, D. Selkoe, 2003, Proceedings of the National Academy of Sciences of the United States of America.

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

Michael S. Wolfe, D. Selkoe, M. Wolfe, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Amyloid-β oligomers: their production, toxicity and therapeutic inhibition

Michael J. Rowan, Dominic M. Walsh, M. Rowan, 2001 .

Complement and microglia mediate early synapse loss in Alzheimer mouse models

Ben A. Barres, Beth Stevens, D. Selkoe, 2016, Science.

Rio Declaration on Environment and Development

D. Selkoe, Dennis J. Selkoe, 1992 .

Imaging Alzheimer's amyloid

D. Selkoe, Dennis J. Selkoe, 2000, Nature Biotechnology.

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

D. Selkoe, Dennis J. Selkoe, 2008, Behavioural Brain Research.

Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease'

Giovanni B. Frisoni, Alfredo Robles, Takeshi Iwatsubo, 1998 .

Alzheimer's Disease: A Central Role for Amyloid

D. Selkoe, Dennis J. Selkoe, 1994, Journal of neuropathology and experimental neurology.

Alzheimer's Disease Aβ Vaccine Reduces Central Nervous System Aβ Levels in a Non-Human Primate, the Caribbean Vervet

Frank R. Ervin, D. Selkoe, R. Palmour, 2004 .

Identification of β-Secretase (BACE1) Substrates Using Quantitative Proteomics

Steven P. Gygi, Joshua E. Elias, S. Gygi, 2009, PloS one.

Certain Inhibitors of Synthetic Amyloid β-Peptide (Aβ) Fibrillogenesis Block Oligomerization of Natural Aβ and Thereby Rescue Long-Term Potentiation

Dominic M. Walsh, D. Selkoe, D. Walsh, 2005, The Journal of Neuroscience.

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice

Weiming Xia, Paul Fraser, J. Rommens, 1997, Nature Medicine.

Alzheimer disease: mechanistic understanding predicts novel therapies.

D. Selkoe, Dennis J. Selkoe, 2004 .

Amyloid β-Protein and the Genetics of Alzheimer's Disease*

D. Selkoe, Dennis J. Selkoe, 1996, The Journal of Biological Chemistry.

Alzheimer's Disease--Genotypes, Phenotype, and Treatments

D. Selkoe, Dennis J. Selkoe, 1997, Science.

The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease

D. Selkoe, Dennis J. Selkoe, 1998 .

The Notch Ligands, Jagged and Delta, Are Sequentially Processed by α-Secretase and Presenilin/γ-Secretase and Release Signaling Fragments*

D. Selkoe, M. LaVoie, Dennis J. Selkoe, 2003, Journal of Biological Chemistry.

Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease

Dominic M. Walsh, D. Selkoe, D. Walsh, 2004, Neuron.

Physiological production of the β-amyloid protein and the mechanism of Alzheimer's disease

Dennis J. Selkoe, 1993, Trends in Neurosciences.

The Impact of Novel Treatments on A\03B2 Burden in Alzheimer's Disease: Insights From a Mathematical Model

Lawrence M. Wein, David L. Craft, L. Wein, 2015 .

The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology

Kenneth S. Kosik, Francisco Lopera, Takaomi C. Saido, 1996, Nature Medicine.

Inflammation and therapeutic vaccination in CNS diseases

Howard L. Weiner, D. Selkoe, H. Weiner, 2002, Nature.

Translating cell biology into therapeutic advances in Alzheimer's disease

D. Selkoe, Dennis J. Selkoe, 1999, Nature.

Amyloid β-protein precursor: new clues to the genesis of Alzheimer's disease

D. Selkoe, Dennis J. Selkoe, 1994, Current Opinion in Neurobiology.

α-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins

Rebecca A. Betensky, Matthew S. Goldberg, D. Selkoe, 2001, Proceedings of the National Academy of Sciences of the United States of America.