Mark J O'Connor

4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.

A. Lau, M. O’Connor, C. Knights, 2008, Journal of medicinal chemistry.

Inhibition of PARP-1 by Olaparib (AZD2281) Increases the Radiosensitivity of a Lung Tumor Xenograft

B. Telfer, D. Hirst, M. O’Connor, 2011, Molecular Cancer Therapeutics.

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

Shridar Ganesan, Jos Jonkers, Piet Borst, 2013, Cancer discovery.

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Carlos Caldas, Matylda Sczaniecka-Clift, Fengtang Yang, 2018, Nature Cell Biology.

Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition.

Alan Ashworth, Nuala McCabe, A. Ashworth, 2006, Cancer research.

Targeting the DNA Damage Response in Cancer.

M. O’Connor, Mark J O'Connor, 2015, Molecular cell.

Gene transfer in Drosophila.

M. O’Connor, W. Chia, Mark J O'Connor, 2002, Methods in molecular biology.