Paul I W de Bakker

发表

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

Peter Kraft, Daniel Wegmann, Cisca Wijmenga, 2012, Nature Genetics.

Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.

Stephan Ripke, Max A Viergever, Matthijs Oudkerk, 2013, Atherosclerosis.

Meta-analysis of genome-wide association studies.

Benjamin M Neale, Mark J Daly, M. Daly, 2010, Cold Spring Harbor protocols.

Fine Mapping Major Histocompatibility Complex Associations in Psoriasis and Its Clinical Subtypes

Vinod Chandran, Buhm Han, Proton Rahman, 2014, American journal of human genetics.

Interrogating the major histocompatibility complex with high-throughput genomics.

Soumya Raychaudhuri, P. D. de Bakker, S. Raychaudhuri, 2012, Human molecular genetics.

Crystallographic refinement by knowledge-based exploration of complex energy landscapes.

Mark A Depristo, Tom L Blundell, M. DePristo, 2005, Structure.

Nature Genetics Advance Online Publication Genetic Association Study of Qt Interval Highlights Role for Calcium Signaling Pathways in Myocardial Repolarization

Michael J Ackerman, Christian Gieger, Thomas Meitinger, 2022 .

A high-quality human reference panel reveals the complexity and distribution of genomic structural variants

Alexander Schönhuth, Victor Guryev, Tobias Marschall, 2016, Nature communications.

Genome-wide association analysis identifies multiple loci related to resting heart rate.

Christian Gieger, Thomas Meitinger, Henry Völzke, 2010, Human molecular genetics.

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes.

Paolo Vineis, Theodore R Holford, Peter Kraft, 2016, Human molecular genetics.

Fine-mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

Cisca Wijmenga, Soumya Raychaudhuri, Gosia Trynka, 2015, Nature Genetics.

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

Jack T Stapleton, Stuart Haber, David Heckerman, 2010, Science.

Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands'

Heorhiy Byelas, Alexandros Kanterakis, David van Enckevort, 2014, European Journal of Human Genetics.

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.

Christian Gieger, Xiaofeng Zhu, Tom R. Gaunt, 2014, American journal of human genetics.

52 Genetic Loci Influencing Myocardial Mass.

Christian Gieger, Thomas Meitinger, Manolis Kellis, 2016, Journal of the American College of Cardiology.

Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control.

Nicole Soranzo, Manuel A. R. Ferreira, Sarah E Medland, 2010, American journal of human genetics.

Genome-wide association study identifies multiple susceptibility loci for diffuse large B-cell lymphoma

Paolo Vineis, Theodore R Holford, Peter Kraft, 2014, Nature Genetics.

Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.

Stephan Ripke, Delnaz Roshandel, Soumya Raychaudhuri, 2013, Arthritis and rheumatism.

Risk for myasthenia gravis maps to a 151Pro→Ala change in TNIP1 and to human leukocyte antigen‐B*08

Soumya Raychaudhuri, David McKee, Henri-Jean Garchon, 2012, Annals of neurology.

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk

Buhm Han, Wei-Min Chen, Soumya Raychaudhuri, 2015, Nature Genetics.

Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies

Marylyn D. Ritchie, Shefali S. Verma, Kelly A. Birdwell, 2015, Genome Medicine.

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

Tom R. Gaunt, Fotios Drenos, Meena Kumari, 2012, American journal of human genetics.

Characteristics of de novo structural changes in the human genome

Alexander Schönhuth, Edwin Cuppen, Victor Guryev, 2015, Genome research.

Genome-wide Association Study Identiﬁes Five Susceptibility Loci for Follicular Lymphoma outside the HLA Region

Jian Gu, Paolo Vineis, Theodore R Holford, 2022 .

Leveraging distant relatedness to quantify human mutation and gene conversion rates

John Wakeley, Alexander Gusev, Sriram Sankararaman, 2015, bioRxiv.

Pooled association tests for rare variants in exon-resequencing studies.

Shamil R Sunyaev, Shaun M Purcell, Lee-Jen Wei, 2010, American journal of human genetics.

STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus.

Wentian Li, Geoffrey Hom, Lars Alfredsson, 2007, The New England journal of medicine.

Accurate and fast multiple-testing correction in eQTL studies.

Eleazar Eskin, Buhm Han, Jae Hoon Sul, 2015, American journal of human genetics.

Evidence for an oligogenic basis of amyotrophic lateral sclerosis.

Leonard H van den Berg, P. D. de Bakker, L. H. van den Berg, 2012, Human molecular genetics.

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

Søren Brunak, Kasper Lage, Jesper V Olsen, 2014, Nature Methods.

Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits

Jia Jia, Ming-Huei Chen, Eric Boerwinkle, 2016, Nature Genetics.

A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping.

Eleazar Eskin, Buhm Han, Jae Hoon Sul, 2013, Human molecular genetics.

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

John Spertus, Markus Perola, Eric Boerwinkle, 2012, The Lancet.

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

Christian Gieger, Ingo Ruczinski, Tom R. Gaunt, 2012, American journal of human genetics.

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

John D Reveille, Michael H Weisman, Linda A Bradbury, 2015, Nature Communications.

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Hynek Pikhart, Tom R. Gaunt, Meena Kumari, 2014, BMJ : British Medical Journal.

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

Mark Woodward, Yoav Ben-Shlomo, Johan Sundström, 2012 .