J. C. Ruble

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Effective Kinetic Resolution of Secondary Alcohols with a Planar- Chiral Analogue of 4-(Dimethylamino)pyridine. Use of the Fe(C5Ph5) Group in Asymmetric Catalysis.

G. C. Fu, J. C. Ruble, H. A. Latham, 1997 .

Kinetic Resolution of Arylalkylcarbinols Catalyzed by a Planar-Chiral Derivative of DMAP: A New Benchmark for Nonenzymatic Acylation.

J. C. Ruble, Gregory C. Fu, Jennifer Tweddell, 1998 .

PET quantification of brain O-GlcNAcase with [18F]LSN3316612 in healthy human volunteers

Mohammad B. Haskali, P. Zanotti-Fregonara, S. Zoghbi, 2020, EJNMMI Research.

Structure-activity relationships of bioisosteres of a carboxylic acid in a novel class of bacterial translation inhibitors.

K. Marotti, D. Romero, M. T. Sweeney, 2007, Bioorganic & medicinal chemistry letters.

Preparation of novel antibacterial agents. Replacement of the central aromatic ring with heterocycles.

D. Rohrer, K. Marotti, A. Thorarensen, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of (-)-PNU-286607 by asymmetric cyclization of alkylidene barbiturates.

P. Toogood, J. C. Ruble, M. R. Barbachyn, 2009, Journal of the American Chemical Society.

Discovery and Characterization of QPT-1, the Progenitor of a New Class of Bacterial Topoisomerase Inhibitors

G. Bammert, A. Hromockyj, K. Marotti, 2008, Antimicrobial Agents and Chemotherapy.

Rhodium-Catalyzed Aldehyde Arylation via Formate-Mediated Transfer Hydrogenation: Beyond Metallic Reductants in Grignard/Nozaki-Hiyami-Kishi-Type Addition.

M. Krische, J. C. Ruble, R. A. Swyka, 2019, Journal of the American Chemical Society.

Assembly of 4-aminoquinolines via palladium catalysis: a mild and convenient alternative to SNAr methodology.

Brandon J. Margolis, J. C. Ruble, S. Pulley, 2007, The Journal of organic chemistry.

Mild Pd-catalyzed N-arylation of methanesulfonamide and related nucleophiles: avoiding potentially genotoxic reagents and byproducts.

J. C. Ruble, Brandon R. Rosen, T. Beauchamp, 2011, Organic letters.

Kinetic Resolution of Arylalkylcarbinols Catalyzed by a Planar-Chiral Derivative of DMAP: A New Benchmark for Nonenzymatic Acylation

G. C. Fu, J. C. Ruble, and Jennifer Tweddell, 1998 .

Route Design and Development of a MET Kinase Inhibitor: A Copper-Catalyzed Preparation of an N1-Methylindazole

M. Yates, J. C. Ruble, M. M. Hansen, 2014 .

Cyclometalated Iridium-PhanePhos Complexes Are Active Catalysts in Enantioselective Allene-Fluoral Reductive Coupling and Related Alcohol-Mediated Carbonyl Additions That Form Acyclic Quaternary Carbon Stereocenters.

Théo P. Gonçalves, Kuo‐Wei Huang, M. Krische, 2019, Journal of the American Chemical Society.

Synthesis and Resolution of Planar‐Chiral Derivatives of 4‐(Dimethylamino)pyridine

Elaine C. Lee, G. C. Fu, J. C. Ruble, 2007 .

Enantioselective Addition of Alcohols to Ketenes Catalyzed by a Planar‐Chiral Azaferrocene: Catalytic Asymmetric Synthesis of Arylpropionic Acids.

G. C. Fu, J. C. Ruble, Brian L. Hodous, 1999 .

An Asymmetric Synthesis of a Chiral Sulfone Acid with Concomitant Hydrolysis and Oxidation to Enable the Preparation of a Glucokinase Activator

J. J. Petkus, Michael E. Laurila, J. Wepsiec, 2012 .

Planar-Chiral Heterocycles as Ligands in Metal-Catalyzed Processes: Enantioselective Addition of Organozinc Reagents to Aldehydes.

P. Dosa, G. C. Fu, J. C. Ruble, 1997, The Journal of organic chemistry.

Development and Scale-Up of a Direct Asymmetric Reductive Amination with Ammonia

J. C. Ruble, H. G. Vandeveer, S. Frank, 2021 .

Improved synthesis of C4α- and C4β-methyl analogues of 2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate.

J. C. Ruble, J. Monn, S. Henry, 2012, Organic letters.

Effective Kinetic Resolution of Secondary Alcohols with a Planar−Chiral Analogue of 4-(Dimethylamino)pyridine. Use of the Fe(C5Ph5) Group in Asymmetric Catalysis

G. C. Fu, J. C. Ruble, A. Latham, 1997 .

A Method for Identifying and Developing Functional Group Tolerant Catalytic Reactions: Application to the Buchwald-Hartwig Amination.

S. Berritt, J. C. Ruble, Elizabeth A Love, 2017, The Journal of organic chemistry.

The kinetic resolution of allylic alcohols by a non-enzymatic acylation catalyst; application to natural product synthesis

S. Bellemin‐Laponnaz, G. C. Fu, J. C. Ruble, 2000 .

Nonenzymatic Kinetic Resolution of Propargylic Alcohols by a Planar−Chiral DMAP Derivative: Crystallographic Characterization of the Acylated Catalyst

G. C. Fu, J. C. Ruble, B. Tao, 1999 .

PET ligands [18F]LSN3316612 and [11C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain

S. Zoghbi, J. Liow, R. Gladding, 2020, Science Translational Medicine.

Discovery and Characterization of QPT-1, the Progenitor of a New Class of Bacterial Topoisomerase Inhibitors (cid:1) †

G. Bammert, A. Hromockyj, K. Marotti, 2008 .

Additives promote Noyori-type reductions of a β-keto-γ-lactam: asymmetric syntheses of serotonin norepinephrine reuptake inhibitors.

G. Stephenson, A. McFarland, J. Wepsiec, 2013, The Journal of organic chemistry.

Quinolin-8-yl Formate: A New Option for Small-Scale Carbonylation Reactions in Microwave Reactors

J. C. Ruble, Sivakumar V. Aathimanikandan, J. Richardson, 2020, Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry.

Nonenzymatic Kinetic Resolution of Propargylic Alcohols by a Planar−Chiral DMAP Derivative: Crystallographic Characterization of the Acylated Catalyst [J. Am. Chem. Soc. 1999, 121, 5091−5092].

G. C. Fu, J. C. Ruble, B. Tao, 1999 .

Hybrid Flow-Batch Model for the Efficient Synthesis of 2(Dimethylamino)-6-methylpyridin-4-ol

María José Nieves-Remacha, J. C. Ruble, J. A. Rincón, 2021, Organic Process Research & Development.

Photo- and Metal-Mediated Deconstructive Approaches to Cyclic Aliphatic Amine Diversification

R. Sarpong, M. Baik, D. Musaev, 2023, Journal of the American Chemical Society.

Enantioselective Construction of Quaternary Stereocenters: Rearrangements of O-Acylated Azlactones Catalyzed by a Planar-Chiral Derivative of 4-(Pyrrolidino)pyridine

G. C. Fu, J. C. Ruble, J. C. R. and, 1998 .