Chun-Mei Hu

发表

Thrombospondin-2 is a Highly Specific Diagnostic Marker and is Associated with Prognosis in Pancreatic Cancer

Hwai I. Yang, Wen-Hwa Lee, Yu-Ting Chang, 2019, Annals of Surgical Oncology.

Redox sensor NPGPx restrains ZAP70 activity and modulates T cell homeostasis.

Wen-Hwa Lee, J. Hsu, Ju-Pi Li, 2021, Free radical biology & medicine.

Characterization of initial key steps of IL-17 receptor B oncogenic signaling for targeted therapy of pancreatic cancer

Y. Jeng, L. Tsai, Wen-Hwa Lee, 2021, Science Translational Medicine.

Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation

Y. Jeng, Wen-Hwa Lee, Yu-Ting Chang, 2022, Nature Communications.

Synthetic lethality by lentiviral short hairpin RNA silencing of thymidylate kinase and doxorubicin in colon cancer cells regardless of the p53 status.

Z. Chang, Chun-Mei Hu, 2008, Cancer research.

Thymidylate kinase is critical for DNA repair via ATM‐dependent Tip60 complex formation

Yu‐Ju Chen, Yi-Ting Wang, Z. Chang, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Hiding human thymidine kinase 1 from APC/C‐mediated destruction by thymidine binding

Z. Chang, Chun-Mei Hu, Po-Yuan Ke, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Tumor cells require thymidylate kinase to prevent dUTP incorporation during DNA repair.

Yu‐Ju Chen, Jim-Min Fang, S. Sheu, 2012, Cancer cell.

Interplays of glucose metabolism and KRAS mutation in pancreatic ductal adenocarcinoma

Wen-Hwa Lee, Chun-Mei Hu, Yu-Huei Liu, 2022, Cell Death & Disease.

Pancreatic cancer-derived small extracellular vesical Ezrin regulates macrophage polarization and promotes metastasis.

Y. Jeng, Yu-Ting Chang, Hsuan-Yu Peng, 2020, American journal of cancer research.

Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation.

Che Ma, Wen-Hwa Lee, Xiaorui Chen, 2022, Cell reports.

NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase.

L. Tsai, H. Shih, Wen-Hwa Lee, 2019, Cell reports.

Podocalyxin‐Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis Pathway

A. Schambach, S. C. Schuyler, L. Sung, 2022, Advanced science.

Switching of N-methyl-D-aspartate (NMDA) receptor-favorite intracellular signal pathways from ERK1/2 protein to p38 mitogen-activated protein kinase leads to developmental changes in NMDA neurotoxicity.

Chun-Mei Hu, Yi-Zhang Chen, Lin Xiao, 2011, The Journal of biological chemistry.

Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors.

Wen-Hwa Lee, Chun-Mei Hu, Hongyuan Chen, 2015, European journal of medicinal chemistry.

A bioluminescent method for measuring thymidylate kinase activity suitable for high-throughput screening of inhibitor.

Z. Chang, Chun-Mei Hu, 2010, Analytical biochemistry.

Mitotic control of dTTP pool: a necessity or coincidence?

Z. Chang, Chun-Mei Hu, 2007, Journal of biomedical science.

A novel small molecule RAD51 inactivator overcomes imatinib-resistance in chronic myeloid leukaemia

Phang-lang Chen, Wen-Hwa Lee, Chi-Fen Chen, 2013, EMBO molecular medicine.

Genome-wide Identification, Classification, and Expression Pattern of Homeobox Gene Family in Brassica rapa under Various Stresses

X. Hou, Chun-Mei Hu, Wenli Wang, 2018, Scientific Reports.

Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate

King-Jen Chang, Y. Jeng, W. Kuo, 2017, Nature Communications.

Cellular 5-hydroxylmethylcytosine content determines tumorigenic potential and prognosis of pancreatic ductal adenocarcinoma.

Y. Jeng, Wen-Hwa Lee, Yu-Ting Chang, 2018, American journal of cancer research.

High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.

Y. Jeng, Wen-Hwa Lee, Yu-Ting Chang, 2019, Cell metabolism.

Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis

Hsi-Wen Yeh, Y. Jou, Chun-Mei Hu, 2017, Oncotarget.

TGF‐β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up‐regulation of IL‐17RB

Chiun-Sheng Huang, King-Jen Chang, Y. Jeng, 2017, EMBO molecular medicine.

Genome-Wide Identification, Classification, and Expression Divergence of Glutathione-Transferase Family in Brassica rapa under Multiple Hormone Treatments

X. Hou, Chun-Mei Hu, N. Khan, 2018, BioMed research international.

Glutathione peroxidase 8 negatively regulates caspase‐4/11 to protect against colitis

E. Y. Lee, Wen-Hwa Lee, J. Hsu, 2019, EMBO molecular medicine.

Genome-Wide Identification, Evolution, and Transcriptional Profiling of PP2C Gene Family in Brassica rapa

Jianjun Wang, M. S. Haider, X. Hou, 2019, BioMed research international.

Evolution and Expression Divergence of E2 Gene Family under Multiple Abiotic and Phytohormones Stresses in Brassica rapa

X. Hou, Chun-Mei Hu, E. Naseri, 2018, BioMed research international.

Complementary Interhelical Interactions between Three Buried Glu-Lys Pairs within Three Heptad Repeats Are Essential for Hec1-Nuf2 Heterodimerization and Mitotic Progression*

Wen-Hwa Lee, Chun-Mei Hu, B. Ngo, 2013, The Journal of Biological Chemistry.

Targeting Reductive Metabolic Shifts by T315I Mutation in BCR-ABL Myeloid Leukemia for Therapy

Z. Chang, Chun-Mei Hu, Sheng-Yang Wu, 2022, bioRxiv.

Effects of GABAB receptor activation on spatial cognitive function and hippocampal neurones in rat models of type 2 diabetes mellitus

Chun-Mei Hu, Xiaojun Cai, Lei Wang, 2017, Bioscience reports.

Differential effects of glucose and N-acetylglucosamine on genome instability.

Y. Jeng, Wen-Hwa Lee, Chun-Mei Hu, 2022, American journal of cancer research.

Combination treatment with breviscapine and netrin-1 suppresses permanent focal cerebral ischemic injury by activating PGE 2 receptor

Yun Zhou, Chun-Mei Hu, Si-si Guo, 2017 .

Efficacy of different drugs in the treatment of minimal hepatic encephalopathy: A network meta‐analysis involving 826 patients based on 10 randomized controlled trials

Chun-Mei Hu, Xiaojun Cai, Lei Wang, 2018, Journal of cellular biochemistry.

Pancreatic cancer‐derived small extracellular vesical ezrin activates fibroblasts to exacerbate cancer metastasis through STAT3 and YAP‐1 signaling pathways

Y. Jeng, Yu-Ting Chang, Ming‐Chu Chang, 2023, Molecular oncology.

The Influence of Daodejing on the Construction of Corporate Culture in Contemporary China

Chun-Mei Hu, 2019 .