A Plückthun

发表

Recent advances in producing and selecting functional proteins by using cell-free translation.

A. Plückthun, L. Jermutus, L. Ryabova, 1998, Current opinion in biotechnology.

Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system.

A. Plückthun, A. Honegger, H. Bosshard, 1997, Journal of immunological methods.

Engineered turns of a recombinant antibody improve its in vivo folding.

A. Plückthun, A. Knappik, A Plückthun, 1995, Protein engineering.

In vitro selection and evolution of proteins.

A. Plückthun, J. Hanes, L. Jermutus, 2000, Advances in protein chemistry.

In vitro selection and evolution of functional proteins by using ribosome display.

A. Plückthun, J. Hanes, A Plückthun, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Circular beta-lactamase: stability enhancement by cyclizing the backbone.

A. Plückthun, A Plückthun, H. Iwai, 1999, FEBS letters.

In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei

I Berger, A. Plückthun, J. Postberg, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Competition BIAcore for measuring true affinities: large differences from values determined from binding kinetics.

L. Nieba, A. Plückthun, A. Krebber, 1996, Analytical biochemistry.

Tailoring in vitro evolution for protein affinity or stability.

A. Plückthun, A. Honegger, J. Hanes, 2001, Proceedings of the National Academy of Sciences of the United States of America.

New protein engineering approaches to multivalent and bispecific antibody fragments.

A. Plückthun, P. Pack, A Plückthun, 1997, Immunotechnology : an international journal of immunological engineering.

Trinucleotide phosphoramidites: ideal reagents for the synthesis of mixed oligonucleotides for random mutagenesis.

A. Plückthun, B. Virnekäs, L. Ge, 1994, Nucleic acids research.

Beyond binding: using phage display to select for structure, folding and enzymatic activity in proteins.

A. Plückthun, P. Forrer, A Plückthun, 1999, Current opinion in structural biology.

Forces and energetics of hapten-antibody dissociation: a biased molecular dynamics simulation study.

A Caflisch, M Karplus, E Paci, 2001, Journal of molecular biology.

Multivalent antibody fragments with high functional affinity for a tumor-associated carbohydrate antigen.

A. Plückthun, A. Lupas, P. Kufer, 1996, Journal of immunology.

A natural antibody missing a cysteine in VH: consequences for thermodynamic stability and folding.

A. Plückthun, A. Honegger, A Plückthun, 1997, Journal of molecular biology.

Zooming in on the hydrophobic ridge of H-2D(b): implications for the conformational variability of bound peptides.

G Capitani, A. Plückthun, A. Tissot, 2001, Journal of molecular biology.

A comparison of strategies to stabilize immunoglobulin Fv-fragments.

R. Glockshuber, A. Plückthun, A Plückthun, 1990, Biochemistry.

Tumor Targeting of Mono-, Di-, and Tetravalent Anti-p185HER-2 Miniantibodies Multimerized by Self-associating Peptides*

A. Plückthun, U. Zangemeister‐Wittke, P. Schubiger, 2001, The Journal of Biological Chemistry.

Expression of functional antibody Fv and Fab fragments in Escherichia coli.

A. Plückthun, A Plückthun, A Skerra, 1989, Methods in enzymology.

Mapping and modification of an antibody hapten binding site: a site-directed mutagenesis study of McPC603.

R. Glockshuber, A. Plückthun, A Plückthun, 1991, Biochemistry.

Protein folding in the periplasm of Escherichia coli

A. Plückthun, C. Wülfing, A Plückthun, 1994, Molecular microbiology.

Tandem immobilized metal-ion affinity chromatography/immunoaffinity purification of His-tagged proteins--evaluation of two anti-His-tag monoclonal antibodies.

A. Plückthun, K. Müller, K. Arndt, 1998, Analytical biochemistry.

A heterodimeric coiled-coil peptide pair selected in vivo from a designed library-versus-library ensemble.

A. Plückthun, S. Michnick, J. Pelletier, 2000, Journal of molecular biology.

In vitro display technologies: novel developments and applications.

A. Plückthun, P. Forrer, P. Amstutz, 2001, Current opinion in biotechnology.

Correctly folded T-cell receptor fragments in the periplasm of Escherichia coli. Influence of folding catalysts.

A. Plückthun, C. Wülfing, A Plückthun, 1994, Journal of molecular biology.

Tetravalent miniantibodies with high avidity assembling in Escherichia coli.

A. Plückthun, R. Zahn, K. Müller, 1995, Journal of molecular biology.

Miniantibodies: use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli.

A. Plückthun, P. Pack, A Plückthun, 1992, Biochemistry.

Sequence statistics reliably predict stabilizing mutations in a protein domain.

S. Steinbacher, B. Steipe, A. Plückthun, 1994, Journal of molecular biology.

Filamentous phage infection: crystal structure of g3p in complex with its coreceptor, the C-terminal domain of TolA.

A Wlodawer, A. Wlodawer, A. Plückthun, 1999, Structure.

Helix-stabilized Fv (hsFv) antibody fragments: substituting the constant domains of a Fab fragment for a heterodimeric coiled-coil domain.

A. Plückthun, K. Arndt, K. Müller, 2001, Journal of molecular biology.

Effects of overexpressing folding modulators on the in vivo folding of heterologous proteins in Escherichia coli.

A. Plückthun, A Plückthun, J. Wall, 1995, Current opinion in biotechnology.