Gregg L Semenza

发表

HIF-1 mediates the Warburg effect in clear cell renal carcinoma

G. Semenza, Gregg L Semenza, 2007, Journal of bioenergetics and biomembranes.

Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology.

G. Semenza, Gregg L Semenza, 2014, Annual review of pathology.

Life with Oxygen

G. Semenza, Gregg L Semenza, 2007, Science.

HIF-dependent antitumorigenic effect of antioxidants in vivo.

Jonathan Pevsner, Linzhao Cheng, Venu Raman, 2007, Cancer cell.

Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases.

Kiichi Hirota, G. Semenza, K. Hirota, 2005, Biochemical and biophysical research communications.

Hydroxylation of HIF-1: oxygen sensing at the molecular level.

G. Semenza, Gregg L Semenza, 2004, Physiology.

Regulation of cancer cell metabolism by hypoxia-inducible factor 1.

G. Semenza, Gregg L Semenza, 2009, Seminars in cancer biology.

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling.

G. Semenza, S. Rey, Gregg L Semenza, 2010, Cardiovascular research.

Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia‐inducible factor 1

G. Semenza, Gregg L Semenza, 2006, Experimental physiology.

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations.

G. Semenza, Gregg L Semenza, 2013, The Journal of clinical investigation.

Cell Type–Specific Regulation of Angiogenic Growth Factor Gene Expression and Induction of Angiogenesis in Nonischemic Tissue by a Constitutively Active Form of Hypoxia-Inducible Factor 1

Kiichi Hirota, P. Campochiaro, G. Semenza, 2003, Circulation research.

Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer

Takashi Tsukamoto, Thomas Hartung, Justin Hanes, 2016, Proceedings of the National Academy of Sciences.

Complementary roles of gasotransmitters CO and H2S in sleep apnea

Gene Kim, S. Snyder, R. Thomas, 2017, Proceedings of the National Academy of Sciences.

Dynamic regulation of stem cell specification and maintenance by hypoxia-inducible factors.

G. Semenza, Gregg L Semenza, 2016, Molecular aspects of medicine.

Hypoxia. Cross talk between oxygen sensing and the cell cycle machinery.

G. Semenza, Gregg L Semenza, 2011, American journal of physiology. Cell physiology.

Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1*

G. Semenza, Daniele M. Gilkes, Maimon E. Hubbi, 2012, The Journal of Biological Chemistry.

Regulation of oxygen homeostasis by hypoxia-inducible factor 1.

G. Semenza, Gregg L Semenza, 2009, Physiology.

Molecular cytogenetic characterization of a subtle interstitial del(3)(p25.3p26.2) in a patient with deletion 3p syndrome.

Julie R Korenberg, J. Korenberg, G. Semenza, 2002, American journal of medical genetics.

Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α

G. Semenza, N. Prabhakar, Ying-Jie Peng, 2002, Proceedings of the National Academy of Sciences of the United States of America.

A Nontranscriptional Role for HIF-1α as a Direct Inhibitor of DNA Replication

Andre Levchenko, Deok-Ho Kim, Kshitiz, 2013, Science Signaling.

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA

Chuanzhao Zhang, Xiaoshun He, G. Semenza, 2016, Proceedings of the National Academy of Sciences.

Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells

Denis Wirtz, G. Semenza, D. Wirtz, 2013, Proceedings of the National Academy of Sciences.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Vasculogenesis, angiogenesis, and arteriogenesis: Mechanisms of blood vessel formation and remodeling

G. Semenza, Gregg L Semenza, 2007, Journal of cellular biochemistry.

Age‐dependent impairment of HIF‐1α expression in diabetic mice: Correction with electroporation‐facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells

Huafeng Zhang, G. Semenza, G. Marti, 2008, Journal of cellular physiology.

HIF-1-dependent respiratory, cardiovascular, and redox responses to chronic intermittent hypoxia.

G. Semenza, N. Prabhakar, Gregg L Semenza, 2007, Antioxidants & redox signaling.

Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

Huafeng Zhang, Jun O. Liu, G. Semenza, 2009, Proceedings of the National Academy of Sciences.

Role of hypoxia-inducible factors in breast cancer metastasis.

G. Semenza, Daniele M. Gilkes, Gregg L Semenza, 2013, Future oncology.

Development of novel therapeutic strategies that target HIF-1

G. Semenza, Gregg L Semenza, 2006, Expert opinion on therapeutic targets.

Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1.

G. Semenza, B. Kelly, R. Fukuda, 2003, Cancer research.

Identification of chemical compounds that induce HIF-1alpha activity.

Ruili Huang, Christopher P Austin, Raymond R Tice, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

HIF-1 and tumor progression: pathophysiology and therapeutics.

G. Semenza, Gregg L Semenza, 2002, Trends in molecular medicine.

Regulation of cell proliferation by hypoxia-inducible factors.

G. Semenza, Maimon E. Hubbi, Gregg L Semenza, 2015, American journal of physiology. Cell physiology.

Reducing bias: accounting for the order of co-first authors.

Arturo Casadevall, Sarah Jackson, A. Casadevall, 2019, The Journal of clinical investigation.

Hypoxia-Inducible Factors in Physiology and Medicine

G. Semenza, Gregg L Semenza, 2012, Cell.

HIF-1beta determines ABCA1 expression under hypoxia in human macrophages.

Gerd Schmitz, Peter Ugocsai, Gerhard Liebisch, 2010, The international journal of biochemistry & cell biology.

Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4

G. Semenza, E. Duh, J. Handa, 2013, Proceedings of the National Academy of Sciences.

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

G. Semenza, B. Kelly, S. Ye, 2005, Blood.

The hypoxic tumor microenvironment: A driving force for breast cancer progression.

G. Semenza, Gregg L Semenza, 2016, Biochimica et biophysica acta.