Barry L Stoddard

发表

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

Philip Bradley, P. Bradley, A. Bogdanove, 2012, Science.

Editorial: Preprints, citations and Nucleic Acids Research

Barry L Stoddard, Keith R Fox, 2019, Nucleic acids research.

The structure of Escherichia coli cytosine deaminase.

Gerry McDermott, G. McDermott, B. Stoddard, 2002, Journal of molecular biology.

The 1.14 A crystal structure of yeast cytosine deaminase: evolution of nucleotide salvage enzymes and implications for genetic chemotherapy.

B. Stoddard, G. Ireton, M. Black, 2003, Structure.

Isolation and characterization of new homing endonuclease specificities at individual target site positions.

B. Stoddard, R. Monnat, M. Chadsey, 2004, Journal of molecular biology.

Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy.

B. Stoddard, G. Ireton, M. Black, 2004, Protein engineering, design & selection : PEDS.

DNA binding and cleavage by the HNH homing endonuclease I-HmuI.

Markus Landthaler, B. Shen, B. Stoddard, 2004, Journal of molecular biology.

Catalytic mechanisms of restriction and homing endonucleases.

B. Stoddard, Barry L Stoddard, Eric A Galburt, 2002, Biochemistry.

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.

Ryo Takeuchi, David Baker, Joel L Sussman, 2012, Nature chemical biology.

Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification.

B. Stoddard, Barry L Stoddard, 2011, Structure.

Tapping natural reservoirs of homing endonucleases for targeted gene modification

Ryo Takeuchi, Kyle Jacoby, Russell J. Dickson, 2011, Proceedings of the National Academy of Sciences.

Metal-dependent DNA cleavage mechanism of the I-CreI LAGLIDADG homing endonuclease.

Monique Turmel, Christian Otis, Claude Lemieux, 2004, Biochemistry.

Folding, DNA recognition, and function of GIY-YIG endonucleases: crystal structures of R.Eco29kI.

B. Stoddard, A. Lambert, Amanda Nga-Sze Mak, 2010, Structure.

Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

Ilya J Finkelstein, Kamyab Javanmardi, Barry L Stoddard, 2019, eLife.

Microseed matrix screening to improve crystals of yeast cytosine deaminase.

B. Stoddard, G. Ireton, Barry L Stoddard, 2004, Acta crystallographica. Section D, Biological crystallography.

I-BasI and I-HmuI: two phage intron-encoded endonucleases with homologous DNA recognition sequences but distinct DNA specificities.

Markus Landthaler, B. Shen, B. Stoddard, 2006, Journal of molecular biology.

Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.

B. Stoddard, A. Korkegian, M. Black, 2008, Journal of molecular biology.

Flexible DNA target site recognition by divergent homing endonuclease isoschizomers I-CreI and I-MsoI.

Monique Turmel, Claude Lemieux, Raymond J Monnat, 2003, Journal of molecular biology.

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer

Michael J MacCoss, David Baker, Alex Zelter, 2016, eLife.

Mutability of an HNH nuclease imidazole general base and exchange of a deprotonation mechanism.

B. Stoddard, R. Monnat, Barry L Stoddard, 2007, Biochemistry.

TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins.

Erin L. Doyle, Daniel F Voytas, A. Bogdanove, 2013, Trends in cell biology.

Coevolution of a homing endonuclease and its host target sequence.

B. Stoddard, M. Scalley‐Kim, Barry L Stoddard, 2007, Journal of molecular biology.

Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase.

B. Stoddard, Barry L Stoddard, J. Pelletier, 2004, Nucleic acids research.

Precise assembly of complex beta sheet topologies from de novo designed building blocks

David Baker, Gaetano T Montelione, Frank DiMaio, 2015, eLife.