Julien Lescar

发表

Ten years of dengue drug discovery: progress and prospects.

David Beer, Hongping Dong, Shahul Nilar, 2013, Antiviral research.

The Hexamer Structure of the Rift Valley Fever Virus Nucleoprotein Suggests a Mechanism for its Assembly into Ribonucleoprotein Complexes

Thomas Walz, Dahai Luo, François Ferron, 2011, PLoS pathogens.

The flavivirus NS2B-NS3 protease-helicase as a target for antiviral drug development.

Dahai Luo, S. Vasudevan, J. Lescar, 2015, Antiviral research.

Polymerases of hepatitis C viruses and flaviviruses: structural and mechanistic insights and drug development.

Stéphane Bressanelli, Pei-Yong Shi, P. Shi, 2014, Antiviral research.

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling

Hongping Dong, Rishi Arora, Xuping Xie, 2016, PLoS pathogens.

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication

Dahai Luo, Subhash G. Vasudevan, Moon Y. F. Tay, 2015, PLoS pathogens.

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

Alexander E. Gorbalenya, Bruno Canard, Bruno Coutard, 2009, Journal of Virology.

Crystallization and X-ray diffraction analysis of the HMG domain of the chondrogenesis master regulator Sox9 in complex with a ChIP-Seq-identified DNA element.

Balasubramanian Moovarkumudalvan, Prasanna R Kolatkar, P. Kolatkar, 2015, Acta crystallographica. Section F, Structural biology communications.

The C-Terminal Segment of the Cysteine-Rich Interdomain of Plasmodium falciparum Erythrocyte Membrane Protein 1 Determines CD36 Binding and Elicits Antibodies That Inhibit Adhesion of Parasite-Infected Erythrocytes

Peter Preiser, J. Lescar, P. Preiser, 2008, Infection and Immunity.

Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

Gérard Bricogne, François Ferron, Bruno Canard, 2011, PLoS pathogens.

Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution

Subhash G. Vasudevan, Bruno Canard, Ting Xu, 2007, Journal of Virology.

Biochemical and Structural Analysis of Helix pomatia Agglutinin

Anne Imberty, Edward P. Mitchell, Christelle Breton, 2006, Journal of Biological Chemistry.

Small Molecule Inhibitors That Selectively Block Dengue Virus Methyltransferase*

Gang Wang, Hongping Dong, Thomas H. Keller, 2010, The Journal of Biological Chemistry.

Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa

Skorn Mongkolsuk, Peter C Dedon, Juthamas Jaroensuk, 2016, Nucleic acids research.

Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope

Hamid Tissire, Karthik Viswanathan, Zachary Shriver, 2015, Cell.

Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery.

Gérard Bricogne, Changqing Li, Bruno Coutard, 2014, Antiviral research.

Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors.

Anders Poulsen, Yan Li, Alex Matter, 2019, ACS infectious diseases.

Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 Å

Subhash G. Vasudevan, Max Nanao, Ting Xu, 2005, Journal of Virology.

Structure of a consensus chitin-binding domain revealed by solution NMR

Ali Miserez, Chandra S. Verma, C. Verma, 2020, bioRxiv.

A Structural Hypothesis for the Transition between Bent and Extended Conformations of the Leukocyte β2 Integrins*

E. Mitchell, J. Lescar, Suet-Mien Tan, 2007, Journal of Biological Chemistry.

Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein

Wolfgang Jahnke, Dahai Luo, Ting Xu, 2008, The EMBO journal.

Dengue Virus Non-Structural Protein 5

J. Lescar, Julien Lescar, Abbas El Sahili, 2014, Viruses.

Biochemical and genetic characterization of dengue virus methyltransferase.

Hongping Dong, Xuping Xie, David C. Chang, 2010, Virology.

Conformational Flexibility of the Dengue Virus RNA-Dependent RNA Polymerase Revealed by a Complex with an Inhibitor

Pei-Yong Shi, Yen-Liang Chen, P. Shi, 2013, Journal of Virology.