J. Gal

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The discovery of biological enantioselectivity: Louis Pasteur and the fermentation of tartaric acid, 1857--a review and analysis 150 yr later.

J. Gal, Joseph Gal, 2008, Chirality.

R-α-Methylbenzyl isothiocyanate, a new and convenient chiral derivatizing agent for the separation of enantiomeric amino compounds by high-performance liquid chromatography

A. Sedman, J. Gal, 1984 .

Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.

J. Gerber, J. Gal, Robert Rhodes, 2004, Chirality.

Application of chemical ionization mass spectrometry to the study of stereoselective in vitro metabolism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane.

P. Callery, J. Gal, N. Castagnoli, 1976, Analytical chemistry.

Neither dapsone hydroxylation nor cortisol 6β-hydroxylation detects the inhibition of CYP3A4 by HIV-1 protease inhibitors

J. Gerber, J. Gal, D. Detmar-Hanna, 1998, European Journal of Clinical Pharmacology.

Louis Pasteur , Chemical Linguist: Founding the Language of Stereochemistry

J. Gal, 2019, Helvetica Chimica Acta.

(+)-cis-1-Acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine [(2R,4S)-(+)-ketoconazole]

J. Gerber, N. Blaton, O. Peeters, 2004 .

(+)-1-{(2S)-2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl}-1H-imidazole mononitrate [(+)-(S)-miconazole nitrate]

N. Blaton, O. Peeters, J. Gal, 2004 .

The effect of aging on the pharmacokinetics and pharmacodynamics of prazosin

J. Gerber, J. Gal, D. Detmar-Hanna, 1996, European Journal of Clinical Pharmacology.

Age and gender influence the stereoselective pharmacokinetics of propranolol.

J. Gerber, J. Gal, A. Nies, 1992, The Journal of pharmacology and experimental therapeutics.

The thermal decomposition of methylphenidate in the gas chromatograph mass spectrometer

J. Gal, B. Flamm, 1975 .

Gas-Chromatographic Determination of Diospyramide With Nitrogen Detection

J. Kett, J. Gal, J. T. Brady, 1980 .

Enantiospecific drug analysis via the ortho-phthalaldehyde/homochiral thiol derivatization method.

J. Gal, D. M. Desai, 1993, Journal of chromatography.

Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates.

J. Gerber, S. Filler, J. Gal, 2004, Chirality.

Beta‐adrenergic receptors in the elderly are not less sensitive to timolol

J. Gerber, J. Gal, A. Nies, 1986, Clinical pharmacology and therapeutics.

Stereoisomerism and drug nomenclature

J. Gal, 1988, Clinical pharmacology and therapeutics.

Convenient synthesis of N-alkoxymethylbarbituric acids and N-alkoxymethylhydantoins.

J. Gal, 1979, Journal of pharmaceutical sciences.

Unbalanced Arginine pathway and altered maturation of pleural macrophages in Th2-deficient mice during Litomosoides sigmodontis filarial infection

S. Chaouch, M. Hübner, J. Gal, 2022, Frontiers in Immunology.

Hydrolysis, methanolysis and ammonolysis of dicarboxylic acids and methyl esters under conditions of chemical ionization mass spectrometry

J. Gal, R. Weinkam, 1976 .

Pharmacokinetics of methylphenidate in the rat using single-ion monitoring GLC-mass spectrometry.

A. Cho, J. Gal, B. J. Hodshon, 1977, Journal of pharmaceutical sciences.

Determination of acetazolamide in biological fluids by high-performance liquid chromatography.

J. Gal, P. Ellis, M. Rendi, 1981, Current eye research.

Propafenone interacts stereoselectively with beta 1- and beta 2-adrenergic receptors.

N. Zahniser, J. Gal, A. Nies, 1988, Journal of cardiovascular pharmacology.

Resolution of the enantiomers of propranolol and other beta-adrenergic antagonists by high-performance liquid chromatography

A. Sedman, J. Gal, 1983 .

Extracorporeal pump assistance — Novel treatment for acute lidocaine poisoning

M. D. Freedman, C. Freed, J. Gal, 2004, European Journal of Clinical Pharmacology.

Early history of the recognition of molecular biochirality.

Pedro Cintas, P. Cintas, J. Gal, 2013, Topics in current chemistry.

The Mass Spectra of Imidoyl Halides and Bromoiminium Bromides

J. Gal, R. Smith, B. A. Phillips, 1973 .

Mechanism of the von Braun amide degradations with carbonyl bromide or phosphorus pentabromide

F. Letourneau, J. Gal, G. Fodor, 1973 .

Molecular chirality: language, history, and significance.

J. Gal, 2015, Topics in current chemistry.

Determination of the enantiomeric composition of salsolinol in biological samples by high-performance liquid chromatography with electrochemical detection.

E. Fontana, J. Gal, V. Bellotti, 1989, Journal of chromatography.

The discovery of stereoselectivity at biological receptors: Arnaldo Piutti and the taste of the asparagine enantiomers--history and analysis on the 125th anniversary.

J. Gal, 2012, Chirality.

Synthesis of cis- and trans-1-(3,4-dimethoxybenzyl)-3,7-dimethyl-5,8-dimethoxy-1,2,3,4-tetrahydroxyisoquinoline. Mechanism of the Bischler-Napieralski reaction

J. Gal, N. Castagnoli, R. Weinkam, 1974 .

Louis Pasteur, language, and molecular chirality. I. Background and dissymmetry.

J. Gal, 2011, Chirality.

High-performance liquid chromatographic chiral stationary phase separation with filament-on thermospray mass spectrometric identification of the enantiomer contaminant (S)-(+)-methamphetamine.

J. Henion, C. Brunner, J. Gal, 1986, Analytical chemistry.

Resolution of the enantiomers of ephedrine, norephedrine and pseudoephedrine by high-performance liquid chromatography

J. Gal, 1984 .

Stereochemistry of Metabolism of Amphetamines: Use of (–)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride for GLC Resolution of Chiral Amines

J. Gal, 1977 .

Synthesis of (R)‐ and (S)‐amphetamine‐d3 from the corresponding phenylalanines

J. Gal, 1977 .

Determination of the absolute configuration and solution conformation of the antifungal agents ketoconazole, itraconazole, and miconazole with vibrational circular dichroism.

J. Gerber, L. Nafie, J. Gal, 2005, Chirality.

Pasteur and the art of chirality.

J. Gal, 2017, Nature chemistry.

Molecular Chirality in Chemistry and Biology: Historical Milestones

J. Gal, 2013 .

Stereoselective determination of the epimer mixtures of itraconazole in human blood plasma using HPLC and fluorescence detection.

J. Gerber, J. Gal, L. Gera, 2011, Chirality.

Improved procedure for determination of flucytosine in human blood plasma by high-pressure liquid chromatography

J. Gal, U. Schwertschlag, L. M. Nakata, 1984, Antimicrobial Agents and Chemotherapy.

■ Studies on stereoselective separations of the "azole" antifungal drugs ketoconazole and itraconazole using HPLC and SFC on silica-based polysaccharides

J. Gal, G. Félix, A. Thienpont, 1999 .

New Single-Isomer Compounds on the Horizon

J. Gal, 2002, CNS Spectrums.

Carl Friedrich Naumann and the introduction of enantio terminology: a review and analysis on the 150th anniversary.

J. Gal, 2007, Chirality.

Stereochemical vocabulary for structures that are chiral but not asymmetric: History, analysis, and proposal for a rational terminology.

J. Gal, 2011, Chirality.

Liquid chromatographic separation of enantiomers of adrenergic agonists.

T. Brown, J. Gal, 1986, Journal of pharmacological methods.

Determination of the Enantiomeric Composition of Chiral Aminoalcohols Using Chiral Derivatization and Reversed-Phase Liquid Chromatography

J. Gal, 1986 .

The so-called "interconversion" of stereoisomeric drugs: an attempt at clarification.

P. Carrupt, B. Testa, J. Gal, 1993, Chirality.

Chiral Drugs from a Historical Point of View

J. Gal, 2006 .

The metabolism of amphetamine in vitro by rabbit liver preparations: a comparison of R(-) and S(+) enantiomers.

A. Cho, J. Gal, J. Wright, 1977, Xenobiotica; the fate of foreign compounds in biological systems.

Gas-chromatographic resolution of enantiomeric secondary alcohols. Stereoselective reductive metabolism of ketones in rabbit-liver cytosol.

J. Gal, D. Devito, T. Harper, 1981, Drug metabolism and disposition: the biological fate of chemicals.

Disposition of (R,S)-tocainide. Some stereoselective aspects.

T. A. French, J. Gal, T. Zysset, 1982, Drug metabolism and disposition: the biological fate of chemicals.

Stereochemistry of tropane quaternizations

A. Bottini, J. Gal, U. D. L. Camp, 1972 .

In vitro reductive metabolism of N-nitrosodibenzylamine: evidence for new reactive intermediates.

J. Gal, C. Estin, B. Moon, 1978, Biochemical and biophysical research communications.

Elevation of beta-adrenergic receptor density in human lymphocytes after propranolol administration.

Perry, P. Molinoff, J. Gal, 1980, The Journal of clinical investigation.

Decomposition of N-nitroso-N-benzhydryl-benzamides and its relation to product partitioning of benzhydryldiazonium and diphenylcarbonium benzoate ion pairs in hydroxylic solvents

E. Stedronsky, J. Gal, R. O'ferrall, 1968 .

Determination of the enantiomeric composition of chiral epoxides using chiral derivatization and liquid chromatography

J. Gal, 1985 .

High-performance liquid chromatographic assay for pilocarpine in aqueous humor.

J. Gal, P. Ellis, M. Rendi, 1984, Journal of Chromatography A.

Serum Binding of Diltiazem in Humans

J. Gal, D. Bloedow, A. Nies, 1982, Journal of clinical pharmacology.

Reversed-phase high-performance liquid chromatographic separation of the stereoisomers of labetalol via derivatization with chiral and non-chiral isothiocyanate reagents.

J. Gal, D. M. Desai, 1992, Journal of chromatography.

Reversed-phase liquid chromatographic separation of enantiomeric and diastereomeric bases related to chloramphenicol and thiamphenicol.

J. Gal, S. Meyer-Lehnert, 1988, Journal of pharmaceutical sciences.

Effect of Ritonavir/Saquinavir on Stereoselective Pharmacokinetics of Methadone: Results of AIDS Clinical Trials Group (ACTG) 401

C. Flexner, A. Hsu, J. Aberg, 2001, Journal of acquired immune deficiency syndromes.

N-Hydroxylation of 1-(2,5-demethoxy-4-methylphenyl)-2-aminopropane by rabbit liver microsomes.

J. Gal, L. Gruenke, N. Castagnoli, 1975, Journal of medicinal chemistry.

Mass spectra of N-[(S)-α-methoxy-α-(trifluoromethyl)phenylacetyl] derivatives of chiral amines. Stereochemistry of amphetamine metabolism in the rat†

J. Gal, 1978 .

Effects of bifunctional interactions in the chemical ionization mass spectrometry of carboxylic acids and methyl esters

J. Gal, R. Weinkam, 1976 .

Proposal for a New Stereochemically Informative Nonproprietary Drug Naming System

Joseph Gal, J. Gal, 2020, Pharmaceutical Medicine.

Signs of the times: the need for a stereochemically informative generic name system.

B. Testa, J. Gal, M. Simonyi, 1989, Trends in pharmacological sciences.

Acidic denitrosation and iodometric determination of N-nitroso compounds

E. Stedronsky, J. Gal, Sidney I. Miller, 1968 .

A Rapid and Simple Microassay for Lidocaine in Human Blood Plasma Using Gas‐Liquid Chromatography with Nitrogen Detection

M. D. Freedman, C. Freed, J. Gal, 1981, Therapeutic drug monitoring.

Pre-column derivatization with fluorescamine and high-performance liquid chromatographic analysis of drugs. Application to tocainide.

A. Sedman, J. Gal, 1982, Journal of chromatography.

High-performance liquid chromatographic resolution of enantiomers of 1-phenyl-2-aminopropanes (amphetamines) with four chiral reagents.

M. Ames, J. Gal, K. J. Miller, 1984, Journal of Chromatography A.

On the Availability of 2,3,4,6-Tetra-O-Acetyl-B-D-Glucopyranosyl Isothiocyanate, a Chiral Derivatizing Agent in HPLC

R. Murphy, J. Gal, 1984 .

Computational Discovery of Novel Low Micromolar Human Pregnane X Receptor Antagonists

Sean Ekins, Ni Ai, Vladyslav Kholodovych, 2008, Molecular Pharmacology.

Use of stable isotopes in studies on the metabolism of amphetamine (1)

A. Cho, J. Gal, R. Kammerer, 1978 .

The Effects of a Cardioselective (Metoprolol) and a Nonselective (Propranolol) Beta‐adrenergic Blocker on the Response to Dynamic Exercise in Normal Men

G D Johnston, G. D. Johnston, H L Brammell, 1982, Circulation.

Excavations in drug chirality: 1. Cyclothiazide.

J. Gal, A. Banerjee, E. Nusser, 1991, Chirality.

Stereochemistry of metabolism of amphetamines: use of (-)-alpha-methoxy-alpha-(trifluoromethyl)phenylacetyl chloride for GLC resolution of chiral amines.

J. Gal, 1977, Journal of pharmaceutical sciences.

Stereospecific gas chromatographic/mass spectrometric assay of the chiral labetalol metabolite 3-amino-1-phenylbutane.

J. Gal, J. Zirrolli, A. Changchit, 1991, Biological mass spectrometry.

Indomethacin-furosemide interaction: the importance of renal blood flow.

J. Gerber, J. Gal, A. Nies, 1983, The Journal of pharmacology and experimental therapeutics.

Hemoperfusion in drug overdose.

B. Rumack, J. Gerber, C. Freed, 1979, JAMA.

Serum tocainide enantiomer concentrations in human subjects.

T. Moyer, A. Sedman, J. Maloney, 1984, British journal of clinical pharmacology.

Reversed-phase LC resolutions of chiral antiarrhythmic agents via derivatization with homochiral isothiocyanates.

J. Gal, D. M. Desai, S. Meyer-Lehnert, 1990, Chirality.

Simultaneous determination of the enantiomers of tocainide in blood plasma using gas-liquid chromatography with electron-capture detection.

A. Sedman, J. Gal, 1984, Journal of chromatography.

Reactions of 2,6-cycloheptadienone and 2,7-cyclooctadienone with primary and secondary amines. Synthesis of tropinones and pseudopelletierines

A. Bottini, J. Gal, 1971 .

Stereoselective hydroxylation of tacrine in rats and humans.

J. Gal, W. Hooper, T. Woolf, 1994, Drug metabolism and disposition: the biological fate of chemicals.

CITATION FOR CHEMICAL BREAKTHROUGH AWARDS: CHOOSING PASTEUR’S AWARD-WINNING PUBLICATION

J. Gal, 2013 .

When did Louis Pasteur present his memoir on the discovery of molecular chirality to the Académie des sciences? Analysis of a discrepancy.

J. Gal, 2008, Chirality.

The role of N-hydroxyamphetamine in the metabolic deamination of amphetamine.

A. Cho, J. Gal, J. Wright, 1977, Life sciences.

Effect of ritonavir/saquinavir on stereoselective pharmacokinetics of methadone: results of AIDS Clinical Trials Group (ACTG) 401.

C. Flexner, A. Hsu, J. Aberg, 2001 .

Different partitioning behaviour of sulphonyl-containing compounds in reversed-phase high-performance liquid chromatography and octanol-water systems

Bernard Testa, Anna Tsantili-Kakoulidou, Nabil El Tayar, 1988 .

Enantioselective versus non‐enantioselective assays in comparative bioavailability studies with racemic drugs

J. Gal, W. Hooper, R. Dickinson, 1992, Biopharmaceutics & drug disposition.

Proposal for a New Stereochemically Informative Nonproprietary Drug Naming System

J. Gal, 2020, Pharmaceutical Medicine.

Single-Isomer Science: The Phenomenon and Its Terminology

J. Gal, 2002, CNS Spectrums.

Metabolism of dimethoxymethyl phenobarbital (Eterobarb) in patients with epilepsy

D. Jenden, M. Goldberg, A. Cho, 1979, Annals of neurology.

In defense of Louis Pasteur: Critique of Gerald Geison's deconstruction of Pasteur's discovery of molecular chirality.

J. Gal, 2019, Chirality.

Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system.

B. Molitoris, A. Sedman, J. Gal, 1986, American journal of nephrology.

In vitro metabolism of amphetamine: an apparent enantiomeric interaction.

A. Cho, J. Gal, J. Wright, 1976, Research communications in chemical pathology and pharmacology.

Synthesis of deuterated analogs of chloromethyl methyl ether

J. Gal, 1975 .

Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.

J. Gerber, J. Gal, Robert Rhodes, 2004, Chirality.

Serum binding of tocainide and its enantiomers in human subjects.

A. Sedman, J. Gal, D. Bloedow, 1982, Research communications in chemical pathology and pharmacology.

Determination of metoprolol in human blood plasma using high-performance liquid chromatography.

J. Gal, A. Nies, G. Johnston, 1983, Journal of chromatography.

COMPLICATIONS OF DISOPYRAMIDE THERAPY

J. Gerber, J. Gal, A. Nies, 1979, The Lancet.

Indomethacin-furosemide interaction: the importance of renal blood flow.

J. Gerber, J. Gal, A. Nies, 1983, Advances in prostaglandin, thromboxane, and leukotriene research.

Louis Pasteur, language, and molecular chirality. I. Background and dissymmetry.

J. Gal, 2011, Chirality.

Short Communication Propafenone Interacts Stereoselectively with β1 and β2-Adrenergic Receptors

N. Zahniser, J. Gal, A. Nies, 1989 .