David A Fidock

发表

Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.

D. Fidock, S. Krishna, A. Uhlemann, 2006, The Journal of infectious diseases.

Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

Serge Batalov, Yingyao Zhou, Yingyao Zhou, 2009, Genome Biology.

Artemisinin Action and Resistance in Plasmodium falciparum.

Leann Tilley, S. Ralph, L. Tilley, 2016, Trends in parasitology.

Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265.

Pradipsinh K Rathod, Xiaoyi Deng, P. Rathod, 2018, ACS infectious diseases.

Spatial and temporal mapping of the PfEMP1 export pathway in Plasmodium falciparum

Mauro Maiorca, Leann Tilley, Eric Hanssen, 2013, Cellular microbiology.

Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase

Graham F Hatfull, D. Fidock, W. Jacobs, 2006, Nature Methods.

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium

Hongshen Ma, Zheng Wang, Jeremy Horst, 2014, Proceedings of the National Academy of Sciences.

Targeting Tuberculosis and Malaria through Inhibition of Enoyl Reductase

David Alland, Hiroyuki Iwamoto, James C Sacchettini, 2003, Journal of Biological Chemistry.

In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes.

D. Fidock, E. Ekland, David A Fidock, 2008, International journal for parasitology.

Discovery of novel inhibitors targeting enoyl-acyl carrier protein reductase in Plasmodium falciparum by structure-based virtual screening.

Ruben Abagyan, George Nicola, James C Sacchettini, 2007, Biochemical and biophysical research communications.

Malaria: progress, perils, and prospects for eradication.

S. Kappe, D. Kyle, D. Fidock, 2008, The Journal of clinical investigation.

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Manuel Llinás, George Papadatos, Sundari Suresh, 2016, PLoS pathogens.

Novel diaryl ureas with efficacy in a mouse model of malaria.

Sean Ekins, Joel S. Freundlich, James C Sacchettini, 2013, Bioorganic & medicinal chemistry letters.