Allen Lovey

Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome.

Johannes C. Hermann, John Menke, Sue Jin, 2013, Bioorganic & medicinal chemistry letters.

Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development.

Binh Vu, L. Vassilev, B. Vu, 2013, ACS medicinal chemistry letters.

Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization

Thelma Thompson, David Fry, Kuo-Sen Huang, 2012, Proceedings of the National Academy of Sciences.

Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity.

Nader Fotouhi, Sung-Sau So, S. So, 2006, Journal of medicinal chemistry.