S Wang

发表

Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa.

P. Lam, R. Knabb, R. Alexander, 2001, Journal of medicinal chemistry.

Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.

M C Nicklaus, Y. Pommier, N. Neamati, 1997, Journal of medicinal chemistry.

Pharmacophores in drug design and discovery.

M C Nicklaus, G. Milne, M. Nicklaus, 1998, SAR and QSAR in environmental research.

Design, synthesis, and structural analysis of influenza neuraminidase inhibitors containing pyrrolidine cores.

W G Laver, S. Muchmore, V. Giranda, 2001, Journal of medicinal chemistry.

Discovery of novel, non-peptide HIV-1 protease inhibitors by pharmacophore searching.

M C Nicklaus, G. Milne, M. Nicklaus, 1996, Journal of medicinal chemistry.

Discovery of HIV-1 integrase inhibitors by pharmacophore searching.

M C Nicklaus, T R Burke, Y. Pommier, 1997, Journal of medicinal chemistry.

Conformational changes of small molecules binding to proteins.

M C Nicklaus, G. Milne, M. Nicklaus, 1995, Bioorganic & medicinal chemistry.

Structure-based approach for the discovery of bis-benzamidines as novel inhibitors of matriptase.

I. Enyedy, R. Dickson, S. Wang, 2001, Journal of medicinal chemistry.

The transition from a pharmacophore-guided approach to a receptor-guided approach in the design of potent protein kinase C ligands.

B Bienfait, B. Bienfait, G. Milne, 1999, Pharmacology & therapeutics.

Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease.

T R Burke, Y. Pommier, N. Neamati, 1996, Journal of medicinal chemistry.

The discovery of novel, structurally diverse protein kinase C agonists through computer 3D-database pharmacophore search. Molecular modeling studies.

D W Zaharevitz, S Wang, G W Milne, 1994, Journal of medicinal chemistry.