G. Milligan

发表

Estradiol improves genital herpes vaccine efficacy in mice.

M. Motamedi, N. Bourne, B. Bell, 2009, Vaccine.

3,4-Methylenedioxymethamphetamine increases susceptibility to genital herpes simplex virus infection in mice.

N. Bourne, K. Cunningham, Jeffry W Pennock, 2009, The Journal of infectious diseases.

Microbial-Based and Material-Based Vaccine Delivery Systems

A. Torres, J. Rudra, G. Milligan, 2014 .

Characterization of lethal dengue virus type 4 (DENV-4) TVP-376 infection in mice lacking both IFN-α/β and IFN-γ receptors (AG129) and comparison with the DENV-2 AG129 mouse model.

A. Barrett, Li Li, E. Harris, 2015, The Journal of general virology.

Type 6 and 19 pneumococcal polysaccharides coupled to erythrocytes elicit pneumococcal cell wall‐specific primary IgM responses and capsular polysaccharide‐specific secondary IgG responses

R. Fairchild, H. Braley‐Mullen, G. Milligan, 1990, European journal of immunology.

Production and characterization of monoclonal antibodies specific for types 6 and 19 pneumococcal capsular polysaccharides.

H. Braley‐Mullen, G. Milligan, 1989, Molecular immunology.

4 – MUCOSAL IMMUNITY OF THE GENITAL TRACT

D. Bernstein, G. Milligan, 2000 .

Entry of Inflammatory Cells Into the Mouse Vagina Following Application of Candidate Microbicides: Comparison of Detergent-Based and Sulfated Polymer–Based Agents

L. Stanberry, N. Bourne, G. Milligan, 2002, Sexually transmitted diseases.

Effector CD4+ T-Cell Involvement in Clearance of Infectious Herpes Simplex Virus Type 1 from Sensory Ganglia and Spinal Cords

Alison Johnson, G. Milligan, C. Chu, 2008, Journal of Virology.

Spectrum of activity testing for therapeutics against all four dengue virus serotypes in AG129 mouse models: Proof‐of‐concept studies with the adenosine nucleoside inhibitor NITD‐008

A. Barrett, N. Bourne, G. Milligan, 2018, Antiviral research.

A lethal model of disseminated dengue virus type 1 infection in AG129 mice.

A. Barrett, N. Bourne, G. Milligan, 2017, The Journal of general virology.

Nonconventional (TL-encoded) major histocompatibility complex molecules present processed viral antigen to cytotoxic T lymphocytes

T. Braciale, G. Milligan, V. Braciale, 1991, The Journal of experimental medicine.

Differential Virological and Immunological Outcome of Severe Acute Respiratory Syndrome Coronavirus Infection in Susceptible and Resistant Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2

C. Peters, S. Makino, C. Tseng, 2009, Journal of Virology.

Status of vaccine research and development of vaccines for Nipah virus.

G. Milligan, B. Satterfield, Brian E Dawes, 2016, Vaccine.

Baseline mapping of severe fever with thrombocytopenia syndrome virology, epidemiology and vaccine research and development

A. Barrett, D. Beasley, Nathen E. Bopp, 2020, NPJ vaccines.

Current status of Severe Fever with Thrombocytopenia Syndrome vaccine development.

A. Barrett, D. Beasley, L. Reece, 2018, Current opinion in virology.

Defining a correlate of protection for chikungunya virus vaccines.

D. Beasley, B. Schnierle, G. Milligan, 2019, Vaccine.

Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development

S. Hallam, A. Barrett, D. Beasley, 2018, npj Vaccines.

Investigating the efficacy of monovalent and tetravalent dengue vaccine formulations against DENV-4 challenge in AG129 mice.

A. Barrett, C. Partidos, N. Bourne, 2014, Vaccine.

Evaluation of immunological markers of ovine vaginal irritation: Implications for preclinical assessment of non-vaccine HIV preventive agents.

M. Motamedi, N. Bourne, G. Vargas, 2017, Journal of reproductive immunology.

T-cell-mediated mechanisms involved in resolution of genital herpes simplex virus type 2 (HSV-2) infection of mice.

G. Milligan, C. Chu, C. G. Young, 2004, Journal of reproductive immunology.

TLR3- and MyD88-Dependent Signaling Differentially Influences the Development of West Nile Virus-Specific B Cell Responses in Mice following Immunization with RepliVAX WN, a Single-Cycle Flavivirus Vaccine Candidate

P. Mason, G. Milligan, E. Winkelmann, 2013, Journal of Virology.

Vaccine Candidate RepliVAX WN , a Single-Cycle Flavivirus in Mice following Immunization with West Nile Virus-Specific B Cell Responses ofDifferentially Influences the Development TLR 3-and MyD 88-Dependent Signaling

P. Mason, G. Milligan, E. Winkelmann, 2013 .

The Host Immune Response, Protective Immunity, and Correlates of Protection

G. Milligan, 2014 .

Effects of candidate vaginally-applied microbicide compounds on innate immune cells.

L. Stanberry, G. Milligan, C. Chu, 2005, Journal of reproductive immunology.

Antibody-mediated protection against genital herpes simplex virus type 2 disease in mice by Fc gamma receptor-dependent and -independent mechanisms.

N. Bourne, G. Milligan, J. E. Strasser, 2007, Journal of reproductive immunology.

Subcapsular sinus macrophages limit dissemination of West Nile virus particles after inoculation but are not essential for the development of West Nile virus-specific T cell responses.

Alison Johnson, P. Mason, D. Widman, 2014, Virology.

Clearance of Herpes Simplex Virus Type 2 by CD8+ T Cells Requires Gamma Interferon and either Perforin- or Fas-Mediated Cytolytic Mechanisms

C. Chalk, G. Milligan, J. E. Strasser, 2005, Journal of Virology.

T Lymphocytes Contribute to Antiviral Immunity and Pathogenesis in Experimental Human Metapneumovirus Infection

R. Garofalo, A. Casola, P. Piedra, 2008, Journal of Virology.

Estrogen receptor alpha (ERalpha) deficiency in macrophages results in increased stimulation of CD4+ T cells while 17beta-estradiol acts through ERalpha to increase IL-4 and GATA-3 expression in CD4+ T cells independent of antigen presentation.

D. Lubahn, D. Estes, G. Milligan, 2005, Journal of immunology.

Interferon-gamma enhances resolution of herpes simplex virus type 2 infection of the murine genital tract.

D. Bernstein, G. Milligan, David I. Bernstein, 1997, Virology.

Herpes simplex virus (HSV)-specific T cells activated in the absence of IFN-gamma express alternative effector functions but are not protective against genital HSV-2 infection.

Alison Johnson, G. Milligan, Michelle H. Nelson, 2010, Journal of reproductive immunology.

Effector CD4 (cid:1) T-Cell Involvement in Clearance of Infectious Herpes Simplex Virus Type 1 from Sensory Ganglia and Spinal Cords (cid:1)

Alison Johnson, G. Milligan, C. Chu, 2008 .

Effect of Candidate Vaginally-Applied Microbicide Compounds on Recognition of Antigen by CD4+ and CD8+ T Lymphocytes1

L. Stanberry, G. Milligan, C. Chu, 2004, Biology of reproduction.

Long-Term Presence of Virus-Specific Plasma Cells in Sensory Ganglia and Spinal Cord following Intravaginal Inoculation of Herpes Simplex Virus Type 2

N. Bourne, G. Milligan, C. Chu, 2005, Journal of Virology.

Long-Term Presence of Virus-Speciﬁc Plasma Cells in Sensory Ganglia and Spinal Cord following Intravaginal Inoculation of Herpes Simplex Virus Type 2 cytokines secreted by local inﬂammatory cells

N. Bourne, G. Milligan, C. Chu, 2005 .

Efficacy of genital T cell responses to herpes simplex virus type 2 resulting from immunization of the nasal mucosa.

G. Milligan, C. Chu, C. G. Young, 2004, Virology.

Role of polymorphonuclear leukocytes in resolution of HSV-2 infection of the mouse vagina.

N. Bourne, G. Milligan, K. L. Dudley, 2001, Journal of reproductive immunology.

Immune protection against HSV-2 in B-cell-deficient mice.

N. Bourne, G. Milligan, K. L. Dudley, 2000, Virology.

Development and Utilization of a Custom PCR Array Workflow: Analysis of Gene Expression in Mycoplasma genitalium and Guinea Pig (Cavia porcellus)

Aaron L. Miller, N. Bourne, G. Milligan, 2014, Molecular Biotechnology.

DNA immunization confers protective immunity on mice challenged intravaginally with herpes simplex virus type 2.

D. Bernstein, L. Stanberry, N. Bourne, 1996, Vaccine.

Generation of humoral immune responses against herpes simplex virus type 2 in the murine female genital tract.

D. Bernstein, G. Milligan, 1995, Virology.

Benzalkonium Chloride Causes Colposcopic Changes and Increased Susceptibility to Genital Herpes Infection in Mice

Massoud Motamedi, Gracie Vargas, Kathleen L Vincent, 2010, Sexually transmitted diseases.

T lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2.

D. Bernstein, N. Bourne, G. Milligan, 1998, Journal of immunology.

Immune Mice Against Reinfection with Herpes the Vaginal Mucosae and Sensory Ganglia of T Lymphocytes Are Required for Protection of

D. Bernstein, N. Bourne, G. Milligan, 1998 .

Neutrophils Aid in Protection of the Vaginal Mucosae of Immune Mice against Challenge with Herpes Simplex Virus Type 2

G. Milligan, 1999, Journal of Virology.

A Lethal Murine Infection Model for Dengue Virus 3 in AG129 Mice Deficient in Type I and II Interferon Receptors Leads to Systemic Disease

A. Barrett, Li Li, N. Bourne, 2014, Journal of Virology.

Regulation of IgG responses by helper and suppressor T cells activated by pneumococcal capsular polysaccharides.

H. Braley‐Mullen, G. Milligan, 1989, Cellular immunology.

Analysis of herpes simplex virus-specific T cells in the murine female genital tract following genital infection with herpes simplex virus type 2.

D. Bernstein, G. Milligan, 1995, Virology.

Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development

S. Hallam, A. Barrett, D. Beasley, 2018, npj Vaccines.

Research and development of Zika virus vaccines

A. Barrett, D. Beasley, J. Hombach, 2016, npj Vaccines.

Control and Eradication of Human and Animal Diseases by Vaccination

N. Bourne, G. Milligan, 2014 .

Baseline mapping of Oropouche virology, epidemiology, therapeutics, and vaccine research and development

A. Barrett, D. Beasley, M. Files, 2022, NPJ vaccines.

A combined carrier-adjuvant system of peptide nanofibers and toll-like receptor agonists potentiates robust CD8+ T cell responses.

J. Rudra, G. Milligan, Brianne N Banasik, 2018, Vaccine.

Immunogenicity of RepliVAX WN, a novel single-cycle West Nile virus vaccine.

P. Mason, N. Bourne, G. Milligan, 2010, Vaccine.

Efficacy and Toxicity of Zinc Salts as Candidate Topical Microbicides against Vaginal Herpes Simplex Virus Type 2 Infection

Nigel Bourne, L. Stanberry, N. Bourne, 2005, Antimicrobial Agents and Chemotherapy.

Dysregulation of Toll-Like Receptor 7 Compromises Innate and Adaptive T Cell Responses and Host Resistance to an Attenuated West Nile Virus Infection in Old Mice

A. Barrett, Y. Cong, G. Xie, 2015, Journal of Virology.

Transcriptional Analysis of the Guinea Pig Mucosal Immune Response to Intravaginal Infection with Herpes Simplex Virus Type 2.

Aaron L. Miller, N. Bourne, G. Milligan, 2018, Virology.

Estrogen Receptor α (ERα) Deficiency in Macrophages Results in Increased Stimulation of CD4+ T Cells while 17β-Estradiol Acts through ERα to Increase IL-4 and GATA-3 Expression in CD4+ T Cells Independent of Antigen Presentation1

D. Lubahn, D. Estes, G. Milligan, 2005, The Journal of Immunology.

Increase IL-4 α-Estradiol Acts through ER β T Cells while 17 + Stimulation of CD 4 Macrophages Results in Increased ) Deficiency in α ( ER α Estrogen Receptor

D. Lubahn, D. Estes, G. Milligan, 2005 .

A soluble divalent class I MHC/IgG1 fusion protein activates CD8+ T cells in vivo.

H. Brunner, C. Chalk, B. Carey, 2005, Clinical immunology.

Mouse models of dengue virus infection for vaccine testing.

A. Barrett, N. Bourne, G. Milligan, 2015, Vaccine.

DESIGNER VACCINES: PRINCIPLES FOR SUCCESSFUL PROPHYLAXIS

G. Milligan, 1998 .

Development of an anti-guinea pig CD4 monoclonal antibody for depletion of CD4+ T cells in vivo.

N. Bourne, G. Milligan, H. Schäfer, 2019, Journal of immunological methods.

In Vivo Rectal Mucosal Barrier Function Imaging in a Large-Animal Model by Using Confocal Endomicroscopy: Implications for Injury Assessment and Use in HIV Prevention Studies

M. Motamedi, N. Bourne, David Szafron, 2016, Antimicrobial Agents and Chemotherapy.

Efﬁcacy and Toxicity of Zinc Salts as Candidate Topical Microbicides against Vaginal Herpes Simplex Virus Type 2 Infection

L. Stanberry, N. Bourne, Rachael Stegall, 2005 .

GRAM-POSITIVE BACTERIA: VACCINE VEHICLES FOR MUCOSAL IMMUNIZATION

G. Milligan, 1998 .

Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2.

Aaron L. Miller, N. Bourne, G. Milligan, 2019, Virology.

Increased Frequency of Virus Shedding by Herpes Simplex Virus 2-Infected Guinea Pigs in the Absence of CD4+ T Lymphocytes

Aaron L. Miller, N. Bourne, G. Milligan, 2018, Journal of Virology.

Virus-Specific Immune Memory at Peripheral Sites of Herpes Simplex Virus Type 2 (HSV-2) Infection in Guinea Pigs

N. Bourne, G. Milligan, Ronald L. Veselenak, 2014, PloS one.

Impact of immunization with glycoprotein D2/AS04 on herpes simplex virus type 2 shedding into the genital tract in guinea pigs that become infected.

L. Stanberry, N. Bourne, Rachael Stegall, 2005, The Journal of infectious diseases.

Early Resolution of Herpes Simplex Virus Type 2 Infection of the Murine Genital Tract Involves Stimulation of Genital Parenchymal Cells by Gamma Interferon

Alison Johnson, G. Milligan, C. Chu, 2006, Journal of Virology.

A Dengue Virus Type 4 Model of Disseminated Lethal Infection in AG129 Mice

A. Barrett, Li Li, E. Harris, 2015, PloS one.

Characterization of the Ovine Vaginal Microbiome and Inflammation Patterns as an Improved Testing Model of Human Vaginal Irritation

M. Motamedi, Aaron L. Miller, N. Richardson-Harman, 2021, Frontiers in Reproductive Health.

Influence of Methamphetamine on Genital Herpes Simplex Virus Type 2 Infection in a Mouse Model

N. Bourne, K. Cunningham, G. Milligan, 2012, Sexually transmitted diseases.

Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates

Gregory D. Gromowski, A. Barrett, D. Beasley, 2023, Nature.

The recognition of a viral antigenic moiety by class I MHC-restricted cytolytic T lymphocytes is limited by the availability of the endogenously processed antigen.

T. Braciale, L. Morrison, G. Milligan, 1990, Journal of immunology.

Rapid clearance of herpes simplex virus type 2 by CD8+ T cells requires high level expression of effector T cell functions.

W. Allman, Alison Johnson, B. Friedrich, 2011, Journal of reproductive immunology.

high level expression of effector T cell functions

W. Allman, Alison Johnson, B. Friedrich, 2011 .

Intrinsic adjuvanting of a novel single-cycle flavivirus vaccine in the absence of type I interferon receptor signaling.

T. Ishikawa, P. Mason, D. Widman, 2012, Vaccine.

Boosting of vaginal HSV-2-specific B and T cell responses by intravaginal therapeutic immunization results in diminished recurrent HSV-2 disease

G. Cohen, Aaron L. Miller, N. Bourne, 2023, Journal of virology.

Mouse models of dengue virus infection for vaccine testing.

A. Barrett, N. Bourne, G. Milligan, 2015, Vaccine.

Rapid clearance of herpes simplex virus type 2 by CD8+ T cells requires high level expression of effector T cell functions.

W. Allman, Alison Johnson, B. Friedrich, 2011, Journal of Reproductive Immunology.

Evaluation of immunological markers of ovine vaginal irritation: Implications for preclinical assessment of non-vaccine HIV preventive agents.

M. Motamedi, N. Bourne, G. Vargas, 2017, Journal of reproductive immunology.

Detection of herpes simplex virus type 2 (HSV-2) -specific cell-mediated immune responses in guinea pigs during latent HSV-2 genital infection.

N. Bourne, S. Auclair, G. Milligan, 2016, Journal of immunological methods.

Adjuvants: Making Vaccines Immunogenic

G. Milligan, 2014 .

Characterization of a murine model of non-lethal, symptomatic dengue virus infection

A. Barrett, Li Li, N. Bourne, 2018, Scientific Reports.

Characterization of lethal dengue virus type 4 (DENV-4) TVP-376 infection in mice lacking both IFN-α/β and IFN-γ receptors (AG129) and comparison with the DENV-2 AG129 mouse model.

A. Barrett, Li Li, E. Harris, 2015, The Journal of general virology.

C. Peters, S. Makino, C. Tseng, 2009, Journal of Virology.