N. Sawtell

发表

Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency

R. L. Thompson, N. Sawtell, R. Thompson, 1992, Journal of virology.

Rapid in vivo reactivation of herpes simplex virus in latently infected murine ganglionic neurons after transient hyperthermia

R. L. Thompson, N. Sawtell, R. Thompson, 1992, Journal of virology.

An avirulent ICP34.5 deletion mutant of herpes simplex virus type 1 is capable of in vivo spontaneous reactivation

A. Nesburn, S. Wechsler, R. L. Thompson, 1995, Journal of virology.

Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene Promotes Neuronal Survival

R. L. Thompson, N. Sawtell, Richard L Thompson, 2001, Journal of Virology.

Conserved tissue-restricted expression of HUC 1-1 actin phenotype among eumetazoan organisms.

J. Lessard, A. Hartman, N. Sawtell, 1990, The Journal of experimental zoology.

Infectious Diseases Division Photo

D. Bernstein, R. Ward, R. Frenck, 2009 .

Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection.

G. Prendergast, D. Munn, C. Karp, 2012, The Journal of infectious diseases.

Herpes simplex virus type 1 dUTPase mutants are attenuated for neurovirulence, neuroinvasiveness, and reactivation from latency

R. L. Thompson, N. Sawtell, R. Pyles, 1992, Journal of virology.

Smooth muscle actin expression during P19 embryonal carcinoma differentiation in cell culture

M. Rudnicki, J. Craig, M. McBurney, 1990, Journal of cellular physiology.

Cellular distribution of smooth muscle actins during mammalian embryogenesis: expression of the alpha-vascular but not the gamma- enteric isoform in differentiating striated myocytes

J. Lessard, N. Sawtell, James L. Lessard, 1989, The Journal of cell biology.

Infectious Herpes Simplex Virus in the Brain Stem Is Correlated with Reactivation in the Trigeminal Ganglia

N. Sawtell, Jessica R. Doll, Richard L Thompson, 2019, Journal of Virology.

Replication of Herpes Simplex Virus Type 1 within Trigeminal Ganglia Is Required for High Frequency but Not High Viral Genome Copy Number Latency

N. Sawtell, Richard L Thompson, 2000, Journal of Virology.

VP16 serine 375 is a critical determinant of herpes simplex virus exit from latency in vivo

S. Triezenberg, N. Sawtell, Richard L Thompson, 2011, Journal of NeuroVirology.

Unique isoactins in the brush border of rat intestinal epithelial cells.

J. Lessard, A. Hartman, N. Sawtell, 1988, Cell motility and the cytoskeleton.

RapidInVivoReactivation ofHerpesSimplex VirusinLatently Infected MurineGanglionic Neuronsafter Transient Hyperthermia

R. L. Thompson, N. Sawtell, Biochemistry Genetics, 1992 .

Efficacy and safety of the oncolytic herpes simplex virus rRp450 alone and combined with cyclophosphamide.

E. Chiocca, Rebecca A. Gillespie, T. Cripe, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Targeted Promoter Replacement Reveals That Herpes Simplex Virus Type-1 and 2 Specific VP16 Promoters Direct Distinct Rates of Entry Into the Lytic Program in Sensory Neurons in vivo

N. Sawtell, Richard L Thompson, R. Thompson, 2019, Front. Microbiol..

Comprehensive quantification of herpes simplex virus latency at the single-cell level

N. Sawtell, 1997, Journal of virology.

HSV latency-associated transcript and neuronal apoptosis.

R. L. Thompson, N. Sawtell, R. Thompson, 2000, Science.

Promyelocytic leukemia (PML) nuclear bodies (NBs) induce latent/quiescent HSV-1 genomes chromatinization through a PML NB/Histone H3.3/H3.3 Chaperone Axis

M. Labetoulle, A. Rousseau, N. Sawtell, 2018, PLoS pathogens.

Promyelocytic Leukemia (PML) Nuclear Bodies (NBs) Induce Latent/Quiescent HSV-1 Genomes Chromatinization Through a PML-NB/Histone H3.3/H3.3 Chaperone Axis

M. Labetoulle, A. Rousseau, N. Sawtell, 2017, bioRxiv.

Alphaherpesvirus Latency and Reactivation with a Focus on Herpes Simplex Virus.

N. Sawtell, Richard L Thompson, R. Thompson, 2020, Current issues in molecular biology.

The Latent Herpes Simplex Virus Type 1 Genome Copy Number in Individual Neurons Is Virus Strain Specific and Correlates with Reactivation

R. L. Thompson, N. Sawtell, D. Poon, 1998, Journal of Virology.

Analysis of Herpes Simplex Virus Reactivation in Explant Reveals a Method-Dependent Difference in Measured Timing of Reactivation

N. Sawtell, Jessica R. Doll, 2017, Journal of Virology.

Comparison of Herpes Simplex Virus Reactivation in Ganglia In Vivo and in Explants Demonstrates Quantitative and Qualitative Differences

R. L. Thompson, N. Sawtell, Richard L Thompson, 2004, Journal of Virology.

Qualitative Differences Explants Demonstrates Quantitative and Reactivation in Ganglia In Vivo and in Comparison of Herpes Simplex Virus

R. L. Thompson, N. Sawtell, 2004 .

De Novo Synthesis of VP16 Coordinates the Exit from HSV Latency In Vivo

N. Sawtell, Richard L Thompson, C. Preston, 2009, PLoS pathogens.

Evidence that the Herpes Simplex Virus Type 1 ICP0 Protein Does Not Initiate Reactivation from Latency In Vivo

R. L. Thompson, N. Sawtell, R. Thompson, 2006, Journal of Virology.

Herpes simplex virus and the lexicon of latency and reactivation: a call for defining terms and building an integrated collective framework

N. Sawtell, Richard L Thompson, R. Thompson, 2016, F1000Research.

HSV-1 Genome Subnuclear Positioning and Associations with Host-Cell PML-NBs and Centromeres Regulate LAT Locus Transcription during Latency in Neurons

D. Theil, M. Labetoulle, A. Rousseau, 2012, PLoS pathogens.

The herpes simplex virus type 1 latency associated transcript locus is required for the maintenance of reactivation competent latent infections

N. Sawtell, Richard L Thompson, R. Thompson, 2011, Journal of NeuroVirology.

Detection and quantification of the rare latently infected cell undergoing herpes simplex virus transcriptional activation in the nervous system in vivo.

N. Sawtell, 2005, Methods in molecular biology.

Analysis of Herpes Simplex Virus ICP0 Promoter Function in Sensory Neurons during Acute Infection, Establishment of Latency, and Reactivation In Vivo

R. L. Thompson, N. Sawtell, M. T. Shieh, 2003, Journal of Virology.

Quantitative Analysis of Herpes Simplex Virus Reactivation In Vivo Demonstrates that Reactivation in the Nervous System Is Not Inhibited at Early Times Postinoculation

N. Sawtell, 2003, Journal of Virology.

Preparation of Single Cells from Solid Tissues for Analysis by PCR

N. Sawtell, 2002, Current protocols in molecular biology.

Early intervention with high-dose acyclovir treatment during primary herpes simplex virus infection reduces latency and subsequent reactivation in the nervous system in vivo.

D. Bernstein, L. Stanberry, R. L. Thompson, 2001, The Journal of infectious diseases.

Promotes Neuronal Survival Latency-Associated Transcript Gene Herpes Simplex Virus Type 1

R. L. Thompson, N. Sawtell, 2001 .

Herpes simplex virus latency and nucleoside analogues.

P. Griffiths, L. Stanberry, H. Field, 1999, Antiviral research.

The Probability of In Vivo Reactivation of Herpes Simplex Virus Type 1 Increases with the Number of Latently Infected Neurons in the Ganglia

N. Sawtell, 1998, Journal of Virology.

Sawtell Ganglia Number of Latently Infected Neurons in the theHerpes Simplex Virus Type 1 Increases with The Probability of In Vivo Reactivation of

N. Sawtell, 1998 .

The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency

R. L. Thompson, N. Sawtell, Richard L Thompson, 1997, Journal of virology.

The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation

A. Nesburn, S. Wechsler, R. L. Thompson, 1996, Journal of virology.

HerpesSimplex VirusType1dUTPaseMutants Are Attenuated forNeurovirulence, Neuroinvasiveness, andReactivation fromLatency

N. Sawtell, Andrichardl . Thompson, 1992 .

Resolution of herpes simplex virus reactivation in vivo results in neuronal destruction

K. Hoebe, N. Sawtell, Jessica R. Doll, 2020, PLoS pathogens.

N M Sawtell simplex virus latency at the single-cell level . Comprehensive quantification of herpes

N. Sawtell, 1997 .

Recurrent vaginal shedding of herpes simplex type 2 virus in the mouse and effects of antiviral therapy.

D. Bernstein, R. Cardin, N. Sawtell, 2010, Antiviral research.

Therapeutic implications of new insights into the critical role of VP16 in initiating the earliest stages of HSV reactivation from latency.

N. Sawtell, Richard L Thompson, R. Thompson, 2010, Future medicinal chemistry.

Inferred father-to-son transmission of herpes simplex virus results in near-perfect preservation of viral genome identity and in vivo phenotypes

Moriah L. Szpara, Daniel W. Renner, N. Sawtell, 2017, Scientific Reports.

De Novo Herpes Simplex Virus VP16 Expression Gates a Dynamic Programmatic Transition and Sets the Latent/Lytic Balance during Acute Infection in Trigeminal Ganglia

N. Sawtell, Richard L Thompson, R. Thompson, 2016, PLoS pathogens.

A Forward Phenotypically Driven Unbiased Genetic Analysis of Host Genes That Moderate Herpes Simplex Virus Virulence and Stromal Keratitis in Mice

Robert W. Williams, M. Kotb, N. Sawtell, 2014, PloS one.

Herpes Simplex Virus DNA Synthesis Is Not a Decisive Regulatory Event in the Initiation of Lytic Viral Protein Expression in Neurons In Vivo during Primary Infection or Reactivation from Latency

R. L. Thompson, N. Sawtell, R. Haas, 2006, Journal of Virology.

A temporal analysis of acyclovir inhibition of induced herpes simplex virus type 1 In vivo reactivation in the mouse trigeminal ganglia.

D. Bernstein, L. Stanberry, N. Sawtell, 1999, The Journal of infectious diseases.

Expression of actin isoforms in developing rat intestinal epithelium.

J. Lessard, A. Hartman, N. Sawtell, 1989, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

HSV Mutant Generation and Dual Detection Methods for Gaining Insight into Latent/Lytic Cycles In Vivo.

N. Sawtell, Richard L Thompson, 2020, Methods in molecular biology.

ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell cultures

R. L. Thompson, N. Sawtell, R L Thompson, 1994, Journal of virology.

Herpes simplex virus mutant generation and dual-detection methods for gaining insight into latent/lytic cycles in vivo.

N. Sawtell, Richard L Thompson, 2014, Methods in molecular biology.