T. Kontani

发表

ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2.

Hiroshi Suzuki, Koji Chono, Kiyomitsu Katsumata, 2010, The Journal of antimicrobial chemotherapy.

N-[2-[(substituted chroman-8-yl)oxy]ethyl]-4-(4-methoxyphenyl)butylamines: synthesis and wide range of antagonism at the human 5-HT1A receptor.

T. Yamaguchi, T. Mase, T. Kontani, 1997, Journal of medicinal chemistry.

Synthesis and pharmacological characterization of novel 6-fluorochroman derivatives as potential 5-HT1A receptor antagonists.

H. Yamashita, T. Yamaguchi, T. Mase, 1998, Journal of medicinal chemistry.

Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: synthesis and structure-activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives.

M. Matsuoka, M. Baba, H. Inoue, 2005, Bioorganic & medicinal chemistry.

Regioselective Alkylation of Thiazolylsulfonamides: Direct and Efficient Synthesis of 3‐Alkylthiazolidene Derivatives

T. Kontani, Ayako Moritomo, M. Ohta, 2005 .

Identification, synthesis, and biological evaluation of 6-[(6R)-2-(4-fluorophenyl)-6-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylphenyl)pyridazin-3(2H)-one (AS1940477), a potent p38 MAP kinase inhibitor.

H. Yamazaki, K. Ohno, M. Takeuchi, 2012, Journal of medicinal chemistry.

Electrical Transport and Optical Properties of Hydrogen-Deficient YH2 Films

Y. Uwatoko, K. Takanashi, T. Kontani, 2004 .

Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides.

M. Matsuoka, M. Baba, H. Inoue, 2004, Bioorganic & medicinal chemistry.

ASP 2151 , a novel helicase – primase inhibitor , possesses antiviral activity against varicella – zoster virus and herpes simplex virus types 1 and 2

Hiroshi Suzuki, Koji Chono, Kiyomitsu Katsumata, 2010 .

Susceptibility of Herpes Simplex Virus Isolated from Genital Herpes Lesions to ASP2151, a Novel Helicase-Primase Inhibitor

Hiroshi Suzuki, A. Weinberg, Koji Chono, 2012, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and Pharmacodynamics of ASP2151, a Helicase-Primase Inhibitor, in a Murine Model of Herpes Simplex Virus Infection

Yoshiaki Ohtsu, Hiroshi Suzuki, Koji Chono, 2012, Antimicrobial Agents and Chemotherapy.

Effect of ASP2151, a Herpesvirus Helicase-Primase Inhibitor, in a Guinea Pig Model of Genital Herpes

Hiroshi Suzuki, Koji Chono, Kiyomitsu Katsumata, 2011, Molecules.

Characterization of virus strains resistant to the herpes virus helicase-primase inhibitor ASP2151 (Amenamevir).

Hiroshi Suzuki, Koji Chono, Kiyomitsu Katsumata, 2012, Biochemical pharmacology.

Anti-Inflammatory Profile of AS2444697, A Novel Interleukin-1 Receptor-Associated Kinase-4 Inhibitor

T. Kontani, E. Imamura, Y. Shimizu, 2011 .

Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors.

S. Kuromitsu, K. Ohno, M. Orita, 2009, Bioorganic & medicinal chemistry.

Design, synthesis, and pharmacological evaluation of N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as interleukin-1 receptor-associated kinase 4 inhibitors with reduced potential for cytochrome P450 1A2 induction.

T. Kontani, E. Imamura, T. Ishikawa, 2023, Bioorganic & medicinal chemistry.

Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists.

M. Takeuchi, T. Kontani, Ayako Moritomo, 2014, Bioorganic & medicinal chemistry.