S. Efstathiou

发表

Influence of Herpes Simplex Virus 1 Latency-Associated Transcripts on the Establishment and Maintenance of Latency in the ROSA26R Reporter Mouse Model

V. Connor, M. Nicoll, J. Proença, 2012, Journal of Virology.

Widespread disruption of host transcription termination in HSV-1 infection

Thomas Bonfert, Caroline C. Friedel, Ralf Zimmer, 2015, Nature Communications.

An efficient selection system for packaging herpes simplex virus amplicons.

S. Inglis, S. Efstathiou, X. Zhang, 1998, The Journal of general virology.

A Systematic Analysis of Host Factors Reveals a Med23-Interferon-λ Regulatory Axis against Herpes Simplex Virus Type 1 Replication

Orland R. Gonzalez, Even Fossum, J. Haas, 2013, PLoS pathogens.

High adenoviral loads stimulate NFκB-dependent gene expression in human vascular smooth muscle cells

S. Efstathiou, D. Proudfoot, G. Clesham, 1998, Gene Therapy.

A quantitative study of the effects of several nucleoside analogues on established herpes encephalitis in mice.

H. Field, J. Anderson, S. Efstathiou, 1984, The Journal of general virology.

Detection of herpes simplex virus-specific DNA sequences in latently infected mice and in humans

A. Minson, H. Field, J. Anderson, 1986, Journal of virology.

Utilization of the herpes simplex virus type 1 latency-associated regulatory region to drive stable reporter gene expression in the nervous system

S. Efstathiou, R. Lachmann, 1997, Journal of virology.

Use of herpes simplex virus type 1 for transgene expression within the nervous system.

S. Efstathiou, R. Lachmann, 1999, Clinical science.

Enhancer stimulation unmasks latent gene transfer after adenovirus-mediated gene delivery into human vascular smooth muscle cells.

H. Browne, S. Efstathiou, G. Clesham, 1996, Circulation research.

A murine RNA polymerase I promoter inserted into the herpes simplex virus type 1 genome is functional during lytic, but not latent, infection.

S. Efstathiou, R. Lachmann, C. Brown, 1996, The Journal of general virology.

Characterization of a novel wood mouse virus related to murid herpesvirus 4

B. Barrell, M. Quail, J. Stewart, 2010, The Journal of general virology.

Tracking the Spread of a lacZ-Tagged Herpes Simplex Virus Type 1 between the Eye and the Nervous System of the Mouse: Comparison of Primary and Recurrent Infection

S. Efstathiou, C. Shimeld, T. Hill, 2001, Journal of Virology.

An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones

V. Connor, M. Nicoll, J. Proença, 2011, The Journal of general virology.

The use of herpes simplex virus-based vectors for gene delivery to the nervous system.

S. Efstathiou, R. Lachmann, 1997, Molecular medicine today.

Elevated Chemokine Responses Are Maintained in Lungs after Clearance of Viral Infection

S. Kunkel, R. Rochford, M. Lutzke, 2002, Journal of Virology.

K3-mediated evasion of CD8(+) T cells aids amplification of a latent gamma-herpesvirus.

U. Koszinowski, P. Stevenson, J. May, 2002, Nature immunology.

K3-mediated evasion of CD8+ T cells aids amplification of a latent γ-herpesvirus

U. Koszinowski, P. Stevenson, J. May, 2002, Nature Immunology.

Interferon Alpha Induces Establishment of Alphaherpesvirus Latency in Sensory Neurons In Vitro

N. De Regge, H. Favoreel, H. Nauwynck, 2010, PloS one.

The limits of protection by “memory” T cells in Ig–/– mice persistently infected with a γ-herpesvirus

P. Doherty, U. Koszinowski, H. Adler, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Towards an understanding of the molecular basis of herpes simplex virus latency.

S. Efstathiou, C. Preston, 2005, Virus research.

A battle for survival: immune control and immune evasion in murine γ-herpesvirus-68 infection

P. Stevenson, S. Efstathiou, J. Boname, 2002 .

Murine Gammaherpesvirus-68 Infection Alters Self-Antigen Presentation and Type 1 Diabetes Onset in NOD Mice1

A. Cooke, Katherine A Smith, S. Efstathiou, 2007, The Journal of Immunology.

Identification of novel herpes simplex virus replicative intermediates by field inversion gel electrophoresis: implications for viral DNA amplification strategies.

S. Efstathiou, X. Zhang, A. Simmons, 1994, Virology.

A Broad Spectrum Secreted Chemokine Binding Protein Encoded by a Herpesvirus

A. Alcamí, C. Stewart, A. Minson, 2000, Journal of Experimental Medicine.

Herpes Simplex Virus 1 Targets the Murine Olfactory Neuroepithelium for Host Entry

P. Stevenson, J. May, M. Nicoll, 2013, Journal of Virology.

DNA HOMOLOGY BETWEEN A NOVEL HUMAN HERPESVIRUS (HHV-6) AND HUMAN CYTOMEGALOVIRUS

M. Craxton, U. Gompels, S. Efstathiou, 1988, The Lancet.

Disruption of the 5' and 3' splice sites flanking the major latency-associated transcripts of herpes simplex virus type 1: evidence for alternate splicing in lytic and latent infections.

I. Brierley, R. Everett, S. Efstathiou, 1998, The Journal of general virology.

Acquisition of the human adeno-associated virus type-2 rep gene by human herpesvirus type-6

S. Efstathiou, R. Honess, B. Thomson, 1991, Nature.

Characterization of a neurovirulent aciclovir-resistant variant of herpes simplex virus.

W. Snowden, Finn E. Grey, G. Darby, 2003, The Journal of general virology.

Two patterns of persistence of herpes simplex virus DNA sequences in the nervous systems of latently infected mice.

P. Speck, B. Slobedman, S. Efstathiou, 1992, The Journal of general virology.

The role of herpes simplex virus type 1 thymidine kinase in pathogenesis.

A. Minson, G. Darby, S. Efstathiou, 1989, The Journal of general virology.

Cloning and molecular characterization of the murine herpesvirus 68 genome.

A. Minson, S. Efstathiou, Y. M. Ho, 1990, The Journal of general virology.

Immune mechanisms in murine gammaherpesvirus-68 infection.

P. Stevenson, S. Efstathiou, 2005, Viral immunology.

Forced lytic replication impairs host colonization by a latency-deficient mutant of murine gammaherpesvirus-68.

P. Stevenson, J. May, S. Efstathiou, 2004, The Journal of general virology.

A historical analysis of herpes simplex virus promoter activation in vivo reveals distinct populations of latently infected neurones

V. Connor, D. Winton, J. Proença, 2008, The Journal of general virology.

Brief report: Primary human herpesvirus 6 infection in a patient following liver transplantation from a seropositive donor

S. Efstathiou, J. Gray, K. Ward, 1989, Journal of medical virology.

Herpes Simplex Virus Type 1 Promoter Activity during Latency Establishment, Maintenance, and Reactivation in Primary Dorsal Root Neurons In Vitro

V. Connor, R. Lachmann, A. Tolkovsky, 2001, Journal of Virology.

Infection with an H2 recombinant herpes simplex virus vector results in expression of MHC class I antigens on the surfaces of human neuroblastoma cells in vitro and mouse sensory neurons in vivo.

S. Efstathiou, A. Abendroth, A. Simmons, 2000, The Journal of general virology.

In vivo imaging of murid herpesvirus-4 infection

M. Alenquer, P. Stevenson, L. Gillet, 2009, The Journal of general virology.

Virological and pathological features of mice infected with murine gamma-herpesvirus 68.

A. Nash, S. Efstathiou, J. Arno, 1992, The Journal of general virology.

Diabetes Onset in NOD Mice Alters Self-Antigen Presentation and Type 1 Murine Gammaherpesvirus-68 Infection

A. Cooke, Katherine A Smith, S. Efstathiou, 2007 .

Edinburgh Research Explorer Permissive and Restricted Virus Infection of Murine Embryonic Stem Cells

J. Haas, P. Kellam, D. Goulding, 2018 .

The detection of latency-associated transcripts of equine herpesvirus 1 in ganglionic neurons.

H. Field, J. M. Whalley, S. Efstathiou, 1995, The Journal of general virology.

Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis.

S. Efstathiou, J. P. Simas, 1998, Trends in microbiology.

Latency associated promoter transgene expression in the central nervous system after stereotaxic delivery of replication-defective HSV-1-based vectors

S. Dunnett, R. Lachmann, E. Torres, 2001, Gene Therapy.

The M2 gene product of murine gammaherpesvirus 68 is required for efficient colonization of splenic follicles but is not necessary for expansion of latently infected germinal centre B cells.

H. Adler, S. Efstathiou, A. Bridgeman, 2004, The Journal of general virology.

Identification of a region of the virus genome involved in murine gammaherpesvirus 68-induced splenic pathology.

J. Stewart, B. Dutia, A. Nash, 2004, The Journal of general virology.

Vaccine potential of a murine gammaherpesvirus-68 mutant deficient for ORF73.

S. Efstathiou, Polly Fowler, 2004, The Journal of general virology.

ORF73 of murine herpesvirus-68 is critical for the establishment and maintenance of latency.

S. Efstathiou, J. P. Simas, S. Marques, 2003, The Journal of general virology.

Selective Gene Expression of Latent Murine Gammaherpesvirus 68 in B Lymphocytes

M. Haury, K. G. Smith, S. Efstathiou, 2003, Journal of Virology.

A Secreted Chemokine Binding Protein Encoded by Murine Gammaherpesvirus-68 Is Necessary for the Establishment of a Normal Latent Load

P. Stevenson, S. Efstathiou, A. Bridgeman, 2001, The Journal of experimental medicine.

Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo.

A. Nash, S. Efstathiou, N. Sunil-Chandra, 1992, The Journal of general virology.

Interactions of murine gammaherpesvirus 68 with B and T cell lines.

A. Nash, S. Efstathiou, N. Sunil-Chandra, 1993, Virology.

Development of Lentivirus-Based Reference Materials for Ebola Virus Nucleic Acid Amplification Technology-Based Assays

Kirsty MacLellan-Gibson, G. Mattiuzzo, P. Minor, 2015, PloS one.

The Effect of Acyclovir on the Acute and Latent Murine Gammaherpesvirus-68 Infection of Mice

A. Nash, S. Efstathiou, N. Sunil-Chandra, 1994 .

WHO collaborative study to assess the suitability of an interim standard for antibodies to Ebola virus

E. Postnikova, R. Tedder, W. Hogrefe, 2016 .

HSV1 latency sites after inoculation in the lip: assessment of their localization and connections to the eye.

M. Labetoulle, F. Lafay, S. Efstathiou, 2003, Investigative ophthalmology & visual science.

Expression from the herpes simplex virus type 1 latency-associated promoter in the murine central nervous system.

S. Efstathiou, R. Lachmann, C. Smith, 2000, The Journal of general virology.

The Herpes Simplex Virus-1 Transactivator Infected Cell Protein-4 Drives VEGF-A Dependent Neovascularization

W. Halford, S. Efstathiou, D. Carr, 2011, PLoS pathogens.

Vaccine potential of a herpes simplex virus type 1 mutant with an essential glycoprotein deleted

S. Inglis, A. Minson, C. S. McLean, 1994, Journal of virology.

Herpes Simplex Virus 1 Replication, Ocular Disease, and Reactivations from Latency Are Restricted Unilaterally after Inoculation of Virus into the Lip

T. Naas, M. Labetoulle, C. Deback, 2019, Journal of Virology.

The HSV-1 Latency-Associated Transcript Functions to Repress Latent Phase Lytic Gene Expression and Suppress Virus Reactivation from Latently Infected Neurons

V. Connor, M. Nicoll, J. Proença, 2016, PLoS pathogens.

Analyses of herpes simplex virus type 1 latency and reactivation at the single cell level using fluorescent reporter mice.

V. Connor, M. Nicoll, J. Proença, 2016, The Journal of general virology.

The molecular basis of herpes simplex virus latency

M. Nicoll, J. Proença, S. Efstathiou, 2012, FEMS microbiology reviews.

An analysis of herpes simplex virus gene expression during latency establishment and reactivation.

M. Sadarangani, H. Atkinson, S. Efstathiou, 1999, The Journal of general virology.

Herpes simplex virus latency and nucleoside analogues.

P. Griffiths, L. Stanberry, H. Field, 1999, Antiviral research.

Quantitative analysis of herpes simplex virus DNA and transcriptional activity in ganglia of mice latently infected with wild-type and thymidine kinase-deficient viral strains.

B. Slobedman, S. Efstathiou, A. Simmons, 1994, The Journal of general virology.

Herpes Simplex Virus Type 1 Latently Infected Neurons Differentially Express Latency-Associated and ICP0 Transcripts

T. Naas, M. Labetoulle, F. Lafay, 2006, Journal of Virology.

Herpes Simplex Virus Type 1 Latently Infected Neurons Differentially Express Latency-Associated and ICP 0 Transcripts

T. Naas, M. Labetoulle, F. Lafay, 2006 .

Intranuclear foci containing low abundance herpes simplex virus latency-associated transcripts visualized by non-isotopic in situ hybridization.

S. Efstathiou, A. Simmons, J. Arthur, 1993, The Journal of general virology.

Immune control of mammalian gamma-herpesviruses: lessons from murid herpesvirus-4.

P. Stevenson, S. Efstathiou, J. P. Simas, 2009, The Journal of general virology.

Investigation of herpes simplex virus type 1 genes encoding multiply inserted membrane proteins.

D. McGeoch, F. Jamieson, M. Elliott, 1991, The Journal of general virology.

The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution.

M. Craxton, U. Gompels, M. Martín, 1995, Virology.

A Heparan-Dependent Herpesvirus Targets the Olfactory Neuroepithelium for Host Entry

P. Stevenson, S. Efstathiou, Ricardo Milho, 2012, PLoS pathogens.

Analysis of murine gammaherpesvirus-68 transcription during lytic and latent infection.

R. Bowden, S. Efstathiou, J. P. Simas, 1999, The Journal of general virology.

Genetic content and preliminary transcriptional analysis of a representative region of murine gammaherpesvirus 68.

M. Chee, J. Stewart, S. Pepper, 1997, The Journal of general virology.

Identification of homologues to the human cytomegalovirus US22 gene family in human herpesvirus 6.

Chris M. Brown, B. Barrell, S. Efstathiou, 1992, The Journal of general virology.

Vaccination against a hit-and-run viral cancer

V. Connor, P. Stevenson, J. May, 2010, The Journal of general virology.

Explorer Permissive and Restricted Virus Infection of Murine Embryonic Stem Cells

J. Haas, P. Kellam, D. Goulding, 2017 .

Permissive and restricted virus infection of murine embryonic stem cells

J. Haas, P. Kellam, D. Goulding, 2012, The Journal of general virology.

In vivo complementation studies of a glycoprotein H-deleted herpes simplex virus-based vector.

P. Speck, A. Minson, S. Efstathiou, 1996, The Journal of general virology.

Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri.

U. Gompels, S. Scott, S. Efstathiou, 1990, The Journal of general virology.

An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response

K. Walters, J. F. Atkins, J. Taubenberger, 2012, Science.

BAFF Receptor Deficiency Limits Gammaherpesvirus Infection

P. Stevenson, J. May, S. Efstathiou, 2014, Journal of Virology.

Herpes virus-based vectors.

A. Minson, S. Efstathiou, 1995, British medical bulletin.

Inhibition of MHC class I-restricted antigen presentation by gamma 2-herpesviruses.

P. Lehner, P. Doherty, P. Stevenson, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Murine gammaherpesvirus 68 encodes tRNA-like sequences which are expressed during latency.

R. Bowden, S. Efstathiou, J. P. Simas, 1997, The Journal of general virology.

A herpesvirus vector can transduce axotomized brain neurons

J. Fawcett, J. Rogers, E. Muir, 2003, Experimental Neurology.

Long-Term Transgene Expression in Mice Infected with a Herpes Simplex Virus Type 1 Mutant Severely Impaired for Immediate-Early Gene Expression

K. R. Marshall, R. Lachmann, S. Efstathiou, 2000, Journal of Virology.

Four tRNA-like sequences and a serpin homologue encoded by murine gammaherpesvirus 68 are dispensable for lytic replication in vitro and latency in vivo.

R. Bowden, S. Efstathiou, J. P. Simas, 1998, The Journal of general virology.

Control of Rta expression critically determines transcription of viral and cellular genes following gammaherpesvirus infection

Kenneth G. C. Smith, P. Lyons, S. Efstathiou, 2007, The Journal of general virology.

Transcription of the murine gammaherpesvirus 68 ORF73 from promoters in the viral terminal repeats.

P. Stevenson, S. Efstathiou, H. Coleman, 2005, The Journal of general virology.

Deletion of the Transcriptional Coactivator HCF-1 In Vivo Impairs the Removal of Repressive Heterochromatin from Latent HSV Genomes and Suppresses the Initiation of Viral Reactivation

Jesse H. Arbuckle, S. Efstathiou, T. Kristie, 2023, mBio.

Gene transfer with herpes simplex vectors.

S. Efstathiou, R. Lachmann, 1999, Current opinion in molecular therapeutics.

HSV vector-delivery of GDNF in a rat model of PD: partial efficacy obscured by vector toxicity

S. Dunnett, C. Monville, E. Torres, 2004, Brain Research.

Cell autonomous regulation of herpes and influenza virus infection by the circadian clock

Rachel S. Edgar, Alessandra Stangherlin, J. O’Neill, 2016, Proceedings of the National Academy of Sciences.

Expression of the herpes simplex virus type 1 latency-associated transcripts does not influence latency establishment of virus mutants deficient for neuronal replication

M. Nicoll, S. Efstathiou, 2013, The Journal of general virology.

Histone modifications associated with herpes simplex virus type 1 genomes during quiescence and following ICP0-mediated de-repression

V. Connor, Finn E. Grey, S. Efstathiou, 2008, The Journal of general virology.

A battle for survival: immune control and immune evasion in murine gamma-herpesvirus-68 infection.

P. Stevenson, S. Efstathiou, J. Boname, 2002, Microbes and infection.

Developing biological standards for vaccine evaluation

G. Mattiuzzo, P. Minor, S. Efstathiou, 2017 .

Direct acoustic profiling of DNA hybridisation using HSV type 1 viral sequences.

M. Cooper, Y. Uludağ, S. Efstathiou, 2008, The Analyst.

In memoriam--Richard M. Elliott (1954-2015).

R. Lamb, R. Tesh, S. Higgs, 2015, Journal of General Virology.

A Broad Spectrum Secreted Chemokine Binding Protein Encoded by a Herpesvirus

A. Alcamí, A. Minson, S. Efstathiou, 2000, The Journal of experimental medicine.

Human Herpesviruses: HSV-1 and 2: molecular basis of HSV latency and reactivation

S. Efstathiou, C. Preston, 2007 .

Soluble chemokine binding proteins are also encoded by herpesviruses.

A. Alcamí, S. Efstathiou, 2000, Immunology today.