C. Allen

A. Hillel, L. Akst, S. Best, 2017, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Prevalence of Diabetes Mellitus and Its Impact on Disease Severity in Adult Recurrent Respiratory Papillomatosis

A. Merati, C. Allen, Chia-Jung Lee, 2013, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Physician Global Assessment as a Disease Activity Measure for Relapsing Polychondritis

Marcus Y. Chen, L. Arnaud, A. Sirajuddin, 2021, Arthritis care & research.

Pathology quiz case 1: diagnosis.

R. Chernock, B. Haughey, C. Allen, 2011, Archives of otolaryngology--head & neck surgery.

Multi-spectral immunofluorescence evaluation of the myeloid, T cell, and natural killer cell tumor immune microenvironment in chordoma may guide immunotherapeutic strategies

G. Gallia, W. Lassoued, M. Miettinen, 2022, Frontiers in Oncology.

Enhanced neoepitope-specific immunity following neoadjuvant PD-L1 and TGF-β blockade in HPV-unrelated head and neck cancer

E. Turkbey, J. Schlom, A. Papanicolau‐Sengos, 2022, The Journal of clinical investigation.

Brush swab as a noninvasive surrogate for tissue biopsies in oral cancer patients to develop clinically translatable epigenetic biomarkers

Dylan F. Roden, Gary Yu, N. Callahan, 2021 .

Preclinical study of a novel therapeutic vaccine for recurrent respiratory papillomatosis

D. Brough, J. Schlom, H. Sabzevari, 2021, NPJ vaccines.

Induction of tumor regression by intratumoral STING agonists combined with anti–programmed death‐L1 blocking antibody in a preclinical squamous cell carcinoma model

C. Allen, Juan Fu, S. Gadkaree, 2017, Head & neck.

PD-1 blockade reverses adaptive immune resistance induced by high-dose hypofractionated but not low-dose daily fractionated radiation

James B. Mitchell, C. Van Waes, J. Friedman, 2018, Oncoimmunology.

Anti-Tumor Immunity in Head and Neck Cancer: Understanding the Evidence, How Tumors Escape and Immunotherapeutic Approaches

C. Van Waes, Zhong Chen, C. Allen, 2015, Cancers.

ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation.

C. Van Waes, S. Sinha, Zhong Chen, 2011, Cancer research.

Tumor and Stem Cell Biology D Np 63 Versatilely Regulates a Broad NFk B Gene Program and Promotes Squamous Epithelial Proliferation , Migration , and Inflammation

S. Sinha, C. Waes, Zhong Chen, 2011 .

Cure of syngeneic carcinomas with targeted IL-12 through obligate reprogramming of lymphoid and myeloid immunity

J. Schlom, Xinping Yang, James B. Mitchell, 2022, JCI insight.

Epigenetic priming of both tumor and NK cells augments antibody-dependent cellular cytotoxicity elicited by the anti-PD-L1 antibody avelumab against multiple carcinoma cell types

J. Schlom, Karin M. Knudson, C. Allen, 2018, Oncoimmunology.

Sicca Syndrome Associated with Immune Checkpoint Inhibitor Therapy.

E. Lipson, D. Kleiner, J. Feliciano, 2019, The oncologist.

Office-Based vs Traditional Operating Room Management of Recurrent Respiratory Papillomatosis: Impact of Patient Characteristics and Disease Severity

A. Merati, E. Tatar, R. Kupfer, 2017, JAMA otolaryngology-- head & neck surgery.

Exploiting the immunogenic potential of standard of care radiation or cisplatin therapy in preclinical models of HPV-associated malignancies

M. Hermsen, C. Allen, N. London, 2022, Journal for ImmunoTherapy of Cancer.

TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer.

C. Van Waes, S. Sinha, Zhong Chen, 2011, Cancer research.

WEE1 kinase inhibition reverses G2/M cell cycle checkpoint activation to sensitize cancer cells to immunotherapy

C. Van Waes, Zhong Chen, Anthony D. Saleh, 2018, Oncoimmunology.

Enhancing direct cytotoxicity and response to immune checkpoint blockade following ionizing radiation with Wee1 kinase inhibition

James B. Mitchell, C. Van Waes, J. Friedman, 2019, Oncoimmunology.

Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma

Dariusz Przybylski, R. Schreiber, N. Marjanovic, 2017, Oncotarget.

Anti-PD-L1 Efficacy Can Be Enhanced by Inhibition of Myeloid-Derived Suppressor Cells with a Selective Inhibitor of PI3Kδ/γ.

C. Van Waes, Zhong Chen, J. Friedman, 2017, Cancer research.

The clinical implications of antitumor immunity in head and neck cancer

R. Uppaluri, C. Allen, J. Bui, 2012, The Laryngoscope.

Overcoming barriers to effective immunotherapy: MDSCs, TAMs, and Tregs as mediators of the immunosuppressive microenvironment in head and neck cancer.

C. Van Waes, C. Allen, R. Davis, 2016, Oral oncology.

Chimeric antigen receptor engineered NK cellular immunotherapy overcomes the selection of T-cell escape variant cancer cells

J. Schlom, J. Friedman, P. Soon-Shiong, 2021, Journal for ImmunoTherapy of Cancer.

Role of activated nuclear factor‐κB in the pathogenesis and therapy of squamous cell carcinoma of the head and neck

C. Van Waes, Zhong Chen, C. Allen, 2007, Head & neck.

Bortezomib-Induced Apoptosis with Limited Clinical Response Is Accompanied by Inhibition of Canonical but not Alternative Nuclear Factor-κB Subunits in Head and Neck Cancer

C. Van Waes, K. Saigal, Zhong Chen, 2008, Clinical Cancer Research.

Improving responses to immunotherapy in head and neck squamous cell carcinoma

R. Ferris, C. Allen, N. Schmitt, 2020, Improving the Therapeutic Ratio in Head and Neck Cancer.

The REASON score: an epigenetic and clinicopathologic score to predict risk of poor survival in patients with early stage oral squamous cell carcinoma

Gary Yu, N. Callahan, B. Aouizerat, 2021, Biomarker Research.

Somatic Mutations in UBA1 Define a Distinct Subset of Relapsing Polychondritis Patients With VEXAS

D. Kastner, N. Young, Marcus Y. Chen, 2021, Arthritis & rheumatology.

Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.

A. Koong, A. Giaccia, Q. Le, 2019, The Journal of clinical investigation.

Nuclear Factor-κB–Related Serum Factors as Longitudinal Biomarkers of Response and Survival in Advanced Oropharyngeal Carcinoma

P. Albert, C. Van Waes, Zhong Chen, 2007, Clinical Cancer Research.

Mechanisms of resistance to T cell‐based immunotherapy in head and neck cancer

C. Allen, Maxwell Y Lee, 2020, Head & neck.

Antigen processing and presentation in cancer immunotherapy

C. Allen, Maxwell Y Lee, C. Sievers, 2020, Journal for ImmunoTherapy of Cancer.

ASTX660, an antagonist of cIAP1/2 and XIAP, increases antigen processing machinery and can enhance radiation-induced immunogenic cell death in preclinical models of head and neck cancer

C. Van Waes, C. Allen, N. Schmitt, 2020, Oncoimmunology.

Antagonist of cIAP1/2 and XIAP enhances anti-tumor immunity when combined with radiation and PD-1 blockade in a syngeneic model of head and neck cancer

C. Van Waes, Zhong Chen, C. Allen, 2018, Oncoimmunology.

A Submucosal True Vocal Fold Mass.

C. Allen, L. Williams, 2015, JAMA otolaryngology-- head & neck surgery.

Molecular and clinical responses in a pilot study of gefitinib with paclitaxel and radiation in locally advanced head-and-neck cancer.

Anurag K. Singh, J. Dancey, D. Citrin, 2010, International journal of radiation oncology, biology, physics.

Combined Inhibition of IAPs and WEE1 Enhances TNFα- and Radiation-Induced Cell Death in Head and Neck Squamous Carcinoma

James B. Mitchell, Ramya Viswanathan, C. Van Waes, 2023, Cancers.

Murray secretion scale and fiberoptic endoscopic evaluation of swallowing in predicting aspiration in dysphagic patients

C. Allen, Chia-Jung Lee, Chu‐Chun Huang, 2017, European Archives of Oto-Rhino-Laryngology.

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer

L. Dang, C. Van Waes, Zhong Chen, 2013, Oncogene.

Syngeneic Mouse Models of Oral Cancer Are Effectively Targeted by Anti–CD44-Based NIR-PIT

P. Choyke, Hisataka Kobayashi, Yuko Nakamura, 2017, Molecular Cancer Research.

Endoscopic Keel Placement to Treat and Prevent Anterior Glottic Webs

R. Paniello, S. Khosla, C. Allen, 2013, The Annals of otology, rhinology, and laryngology.

Human papillomavirus and oropharynx cancer: Biology, detection and clinical implications

S. El-Mofty, J. Lewis, B. Nussenbaum, 2010, The Laryngoscope.

Determining if T cell antigens are naturally processed and presented on HLA class I molecules

J. Friedman, Christian S. Hinrichs, C. Allen, 2022, BMC immunology.

Cisplatin Alters Antitumor Immunity and Synergizes with PD-1/PD-L1 Inhibition in Head and Neck Squamous Cell Carcinoma

C. Van Waes, C. Allen, E. Moore, 2017, Cancer Immunology Research.

Resistance to CTLA-4 checkpoint inhibition reversed through selective elimination of granulocytic myeloid cells

C. Van Waes, Zhong Chen, J. Friedman, 2017, Oncotarget.

Oral Hairy Leukoplakia in an HIV-Negative Patient

R. Chernock, C. Allen, E. Graboyes, 2013, Ear, nose, & throat journal.

Tumor and Stem Cell Biology TNF-a Promotes c-REL / D Np 63 a Interaction and TAp 73 Dissociation from Key Genes That Mediate Growth Arrest and Apoptosis in Head and Neck Cancer

S. Sinha, C. Waes, Zhong Chen, 2011 .

Immune Landscape and Role of Immunotherapy in Treatment of HPV-Associated Head and Neck Squamous Cell Carcinoma (HNSCC)

Hannah R. Turbeville, Tiffany A. Toni, C. Allen, 2022, Current Otorhinolaryngology Reports.

Immunotherapy for HPV Malignancies.

C. Allen, Maxwell Y Lee, 2021, Seminars in radiation oncology.

Enhanced Tumor Control with Combination mTOR and PD-L1 Inhibition in Syngeneic Oral Cavity Cancers

C. Van Waes, R. Uppaluri, C. Allen, 2016, Cancer Immunology Research.

Tracheal mass. Malignant melanoma metastatic to the trachea.

C. Allen, Patricia L. Purcell, T. Meyer, 2015, JAMA otolaryngology-- head & neck surgery.

Clinical Assessment and Treatment of the Dysfunctional Larynx after Radiation

A. Merati, C. Allen, Chia-Jung Lee, 2013, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Comparative Analysis of Tumor-Infiltrating Lymphocytes in a Syngeneic Mouse Model of Oral Cancer

Ravindra Uppaluri, R. Uppaluri, C. Allen, 2012, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Neoadjuvant PD-1 Immune Checkpoint Blockade Reverses Functional Immunodominance among Tumor Antigen–Specific T Cells

C. Van Waes, J. Friedman, H. Schreiber, 2019, Clinical Cancer Research.

Tumor cell HLA class I expression and pathologic response following neoadjuvant immunotherapy for newly diagnosed head and neck cancer.

J. Friedman, W. Lassoued, J. Gulley, 2023, Oral oncology.

Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis

J. Schlom, J. Friedman, J. Gulley, 2021, Journal for ImmunoTherapy of Cancer.

Preclinical study of a novel therapeutic vaccine for recurrent respiratory papillomatosis

D. Brough, J. Schlom, H. Sabzevari, 2021, npj Vaccines.

Biologics for the Treatment of Recurrent Respiratory Papillomatosis.

C. Allen, 2021, Otolaryngologic clinics of North America.

How Enhancing Immunity to Low‐Risk HPV Could Cure Recurrent Respiratory Papillomatosis

C. Allen, Kevin Bai, 2021, The Laryngoscope.

mTOR and MEK1/2 inhibition differentially modulate tumor growth and the immune microenvironment in syngeneic models of oral cavity cancer

C. Van Waes, R. Uppaluri, C. Allen, 2015, Oncotarget.

Durable response in a patient with recurrent respiratory papillomatosis treated with immune checkpoint blockade

J. Friedman, Christian S. Hinrichs, C. Allen, 2022, Head & neck.

S. Pavletic, C. Allen, A. McBride, 2021, Clinical case reports.

Established T Cell–Inflamed Tumors Rejected after Adaptive Resistance Was Reversed by Combination STING Activation and PD-1 Pathway Blockade

C. Van Waes, C. Allen, E. Moore, 2016, Cancer Immunology Research.

Defining Clinical Subgroups in Relapsing Polychondritis: A Prospective Observational Cohort Study

Marcus Y. Chen, Casey A. Rimland, A. Sirajuddin, 2020, Arthritis & rheumatology.

Anatomic Derkay Score Is Associated with Voice Handicap in Laryngeal Papillomatosis in Adults

A. Merati, C. Allen, Emel Çadallı Tatar, 2016, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Proteomic Signatures of Epidermal Growth Factor Receptor and Survival Signal Pathways Correspond to Gefitinib Sensitivity in Head and Neck Cancer

Xiaojiang Xu, Jay Friedman, C. Van Waes, 2009, Clinical Cancer Research.

Avoiding phagocytosis-related artifact in myeloid derived suppressor cell T-lymphocyte suppression assays.

C. Allen, Christopher Silvin, R. Davis, 2017, Journal of immunological methods.

Brush swab as a noninvasive surrogate for tissue biopsies in epigenomic profiling of oral cancer

Dylan F. Roden, Gary Yu, B. Aouizerat, 2021, Biomarker research.

Phenotypic plasticity and reduced tissue retention of exhausted tumor-infiltrating T cells following neoadjuvant immunotherapy in head and neck cancer.

Marco Craveiro, R. Chari, J. Schlom, 2023, Cancer cell.

Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC)

James B. Mitchell, C. Van Waes, Zhong Chen, 2023, Cell Death & Differentiation.

CCR 20 th Anniversary Commentary: Preclinical StudyofProteasomeInhibitorBortezomibinHead and Neck Cancer

B. Conley, C. Waes, J. Sunwoo, 2015 .

Role of activated nuclear factor‐κB in the pathogenesis and therapy of squamous cell carcinoma of the head and neck

C. Van Waes, C. Waes, Zhong Chen, 2007 .

Oncogenic Ras and ΔNp63α cooperate to recruit immunosuppressive polymorphonuclear myeloid-derived suppressor cells in a mouse model of squamous cancer pathogenesis

C. Van Waes, Zhong Chen, A. George, 2023, Frontiers in Immunology.

SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck

J. Licht, Sohyoung Kim, R. Chari, 2023, Cell reports.

BASIC SCIENCE REVIEW

R. Ferris, C. Waes, Zhong Chen, 2007 .

Comprehensive multiomic characterization of human papillomavirus-driven recurrent respiratory papillomatosis reveals distinct molecular subtypes

C. Van Waes, X. Yang, J. Friedman, 2021, Communications Biology.

ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation.

C. Van Waes, S. Sinha, Zhong Chen, 2011, Cancer research.

Neurotrophin Pathway Receptors NGFR and TrkA Control Perineural Invasion, Metastasis, and Pain in Oral Cancer

J. Slater, Gary Yu, N. Callahan, 2022, Advances in Biology.

Abstract 6042: TNFa co-activates IKK/NF-kB/RELA prosurvival and WEE1-CDC2 G2/M checkpoint signaling and is targetable by WEE1 antagonist AZD1775 in head and neck cancer

Ramya Viswanathan, C. Waes, Zhong Chen, 2020 .

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.

Comparative Analysis of Tumor-Infiltrating Lymphocytes in a Syngeneic Mouse Model of Oral Cancer

R. Uppaluri, C. Allen, Ashley E. Winkler, 2012, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.