Berit Powers

Antisense therapy in a new rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment

M. Feany, F. Rigo, A. Messing, 2021, bioRxiv.

Antisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment

M. Feany, F. Rigo, A. Messing, 2021, Science Translational Medicine.

The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration

F. Rigo, J. Matson, P. Jafar-Nejad, 2020, bioRxiv.

Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS

F. Rigo, T. Ishii, T. Uchihara, 2021, Nature Biotechnology.

Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease

A. Messing, G. Hung, E. Swayze, 2018, Annals of neurology.

Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease

F. Rigo, P. Tesar, D. Schlatzer, 2020, Nature.