I. Higuchi

K. Arimura, M. Nakagawa, S. Izumo, 1996, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Fibronectin receptor reduction in skin and fibroblasts of patients with Ullrich's disease

M. Osame, I. Higuchi, A. Saito, 2002, Muscle & nerve.

Different manners of sarcoglycan expression in genetically proven α-sarcoglycan deficiency and γ-sarcoglycan deficiency

K. Arimura, M. Nakagawa, M. Osame, 1998, Acta Neuropathologica.

Different manners of sarcoglycan expression in genetically proven alpha-sarcoglycan deficiency and gamma-sarcoglycan deficiency.

K. Arimura, M. Nakagawa, M. Osame, 1998, Acta Neuropathologica.

Miyoshi myopathy patients with novel 5' splicing donor site mutations showed different dysferlin immunostaining at the sarcolemma

M. Nakagawa, Toshiaki Takahashi, M. Aoki, 2002, Acta Neuropathologica.

Type II muscle fibers are stained by anti-Fas antibody

M. Nakagawa, M. Osame, I. Higuchi, 1995, Journal of the Neurological Sciences.

Abnormal expression of proteoglycans in Ullrich's disease with collagen VI deficiency

K. Arimura, M. Osame, I. Higuchi, 2006, Muscle & nerve.

Vacuolar myositis with expression of both MHC class I and class II antigens on skeletal muscle fibers

M. Nerenberg, K. Arimura, M. Osame, 1991, Journal of the Neurological Sciences.

Myocardial patchy staining of dystrophin in Becker's muscular dystrophy associated with cardiomyopathy.

M. Osame, I. Higuchi, A. Kisanuki, 1992, American heart journal.

Perivascular T cells are infected with HTLV-I in the spinal cord lesions with HTLV-I-associated myelopathy/tropical spastic paraparesis: double staining of immunohistochemistry and polymerase chain reaction in situ hybridization

E. Sato, Y. Isashiki, S. Izumo, 1998, Acta Neuropathologica.

Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis.

K. Arimura, M. Nakagawa, S. Izumo, 1996, Journal of neurovirology.

Pathological changes in skeletal muscle in HTLV-I-associated myelopathy

K. Arimura, M. Osame, I. Higuchi, 1992, Journal of the Neurological Sciences.

Failure to detect HTLV‐I by in situ hybridization in the biopsied muscles of viral carriers with polymyositis

M. Nerenberg, K. Tajima, M. Osame, 1992, Muscle & nerve.

M. Nakagawa, M. Osame, I. Higuchi, 1994, Internal medicine.

Neuropathology of HTLV‐I‐Associated Myelopathy—A Report of Two Autopsy Cases—

S. Izumo, M. Osame, I. Higuchi, 1992, Acta paediatrica Japonica : Overseas edition.

Skeletal muscle abnormalities in two patients with dystonia

K. Arimura, M. Osame, I. Higuchi, 2002, Acta Neuropathologica.

Quantitative computed tomography for enzyme replacement therapy in Pompe disease

E. Nanba, Y. Maegaki, I. Higuchi, 2012, Brain and Development.

Adult T‐cell leukemia predominantly involving exocrine glands

M. Osame, I. Higuchi, M. Saito, 2004, European journal of haematology.

STUDY OF CYTOCHROME C OXIDASE WITH A MONOCLONAL ANTIBODY IN MITOCHONDRIAL MYOPATHY

M. Osame, I. Higuchi, H. Fukunaga, 2009 .

Experimental germanium myopathy

M. Nakagawa, S. Izumo, M. Osame, 2004, Acta Neuropathologica.

Chronic Low-Dose Methylmercury Administration Decreases Mitochondrial Enzyme Activities and Induces Myopathic Changes in Rats

I. Higuchi, A. Yasutake, F. Usuki, 2001 .

The effect of methylmercury on skeletal muscle in the rat: a histopathological study.

I. Higuchi, A. Yasutake, F. Umehara, 1998, Toxicology letters.

Experimental simvastatin-induced myopathy in rabbits

K. Arimura, M. Nakagawa, M. Osame, 1992, Journal of the Neurological Sciences.

IMMUNOHISTOCHEMICAL STUDY OF CYTOCHROME COXIDASE WITH A MONOCLONAL ANTIBODY IN MITOCHONDRIAL MYOPATHY

M. Nakagawa, M. Osame, I. Higuchi, 1988 .

Profile of cognitive function in adults with duchenne muscular dystrophy

S. Suwazono, I. Higuchi, Yukihiko Ueda, 2017, Brain and Development.

A rat model of human T lymphocyte virus type I (HTLV-I) infection: in situ detection of HTLV-I provirus DNA in microglia/macrophages in affected spinal cords of rats with HTLV-I-induced chronic progressive myeloneuropathy

H. Ikeda, T. Yoshiki, I. Yamashita, 1999, Acta Neuropathologica.

Immunohistochemical characteristics of polymyositis in patients with HTLV‐1–associated myelopathy and HTLV‐I carriers

M. Osame, I. Higuchi, M. Inose, 1993, Muscle & nerve.

Dropped Head Syndrome and the Presence of Rimmed Vacuoles in a Muscle Biopsy in Scleroderma-polymyositis Overlap Syndrome Associated with Anti-Ku Antibody

I. Higuchi, M. Jonosono, Mai Yoshida, 2017, Internal medicine.

Deficiency of a 180-kDa extracellular matrix protein in Fukuyama type congenital muscular dystrophy skeletal muscle

Y. Sunada, K. Matsumura, I. Higuchi, 2002, Neuromuscular Disorders.

Characteristic expression of cell adhesion molecules in adhalin deficiency

K. Arimura, M. Nakagawa, M. Osame, 1996, Journal of the Neurological Sciences.

Neuroleptic malignant syndrome

I. Higuchi, M. Araki, A. Takagi, 1988, Neurology.

Determination of urine thiocyanate in patients with amyotrophic lateral sclerosis

M. Nakagawa, S. Izumo, M. Osame, 1984, Acta neurologica Scandinavica.

New type of encephalomyelitis responsive to trimethoprim/sulfamethoxazole treatment in Japan

H. Wakaguri, M. Goto, R. Hirano, 2015, Neurology: Neuroimmunology & Neuroinflammation.

Reappearance of embryonic neutral α-glucosidase isoenzyme in acid maltase-deficient muscle of Japanese quail

S. Ishiura, I. Higuchi, H. Sugita, 1988, Experimental Neurology.

Targeted Deletion of Both Thymidine Phosphorylase and Uridine Phosphorylase and Consequent Disorders in Mice

M. Fukushima, T. Noda, K. Miyazono, 2002, Molecular and Cellular Biology.

Different pattern of HSP47 expression in skeletal muscle of patients with neuromuscular diseases

K. Arimura, E. Matsuura, M. Osame, 2007, Neuromuscular Disorders.

Phenotypic variation in a large Japanese family with Miyoshi myopathy with nonsense mutation in exon 19 of dysferlin gene

M. Nakagawa, H. Takashima, K. Goto, 2001, Journal of the Neurological Sciences.

Accumulation of mitochondrial ATP synthase subunit c in muscle in a patient with neuronal ceroid lipofuscinosis (late infantile form)

J. Ezaki, E. Kominami, M. Osame, 1997, Acta Neuropathologica.

Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase.

A. Fukamizu, J. Ishida, S. Aratani, 2009, International journal of molecular medicine.

Autosomal dominant early onset dementia and leukoencephalopathy in a Japanese family: clinical, neuroimaging and genetic studies

K. Arimura, M. Nakagawa, M. Nagai, 1997, Journal of the Neurological Sciences.

Partial deficiency of emerin caused by a splice site mutation in EMD.

E. Matsuura, H. Takashima, A. Yoshimura, 2014, Internal medicine.

Acid maltase deficiency in the Japanese quail; early morphological event in skeletal muscle

I. Nonaka, S. Ishiura, I. Higuchi, 2004, Acta Neuropathologica.

The main HTLV-I-harboring cells in the muscles of viral carriers with polymyositis are not macrophages but CD4+ lymphocytes

K. Arimura, M. Nakagawa, R. Rosales, 1996, Acta Neuropathologica.

Detection of HTLV‐I provirus by in situ polymerase chain reaction in mononuclear inflammatory cells in skeletal muscle of viral carriers with polymyositis

K. Arimura, M. Nakagawa, S. Izumo, 1995, Muscle & nerve.

High AMP deaminase activity in rimmed vacuoles of skeletal muscle

I. Nonaka, S. Ishiura, I. Higuchi, 1986, Journal of the Neurological Sciences.

Capillary changes in skeletal muscle of patients with Ullrich's disease with collagen VI deficiency

K. Arimura, M. Nakagawa, T. Hashiguchi, 2003, Acta Neuropathologica.

MRI studies of spinal visceral larva migrans syndrome

K. Arimura, E. Matsuura, M. Osame, 2006, Journal of the Neurological Sciences.

[Case of hypertrophic meningitis with vasculitis syndrome].

I. Maruyama, M. Osame, K. Nakahara, 1994, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

Frameshift mutation in the collagen VI gene causes Ullrich's disease

K. Arimura, M. Nakagawa, T. Hashiguchi, 2001, Annals of neurology.

Cardiac involvement in mitochondrial diseases. A study on 17 patients with documented mitochondrial DNA defects.

M. Miyata, M. Nakagawa, M. Osame, 1995, Circulation.

Molecular mechanism of rigid spine with muscular dystrophy type 1 caused by novel mutations of selenoprotein N gene

K. Arimura, M. Nakagawa, R. Hirano, 2006, Neurogenetics.

A new type of hereditary motor and sensory neuropathy linked to chromosome 3

K. Arimura, M. Nakagawa, S. Izumo, 1997, Annals of neurology.

Genetically Confirmed Patients with Merosin-deficient Congenital Muscular Dystrophy in China

K. Arimura, H. Takashima, I. Higuchi, 2008, Neuropediatrics.

Steroid-responsive myalgia in a patient with Becker muscular dystrophy

Koichiro Nakamura, M. Nakagawa, M. Osame, 1993, Journal of the Neurological Sciences.

Two patients with distal muscular dystrophy and autonomic nerve dysfunction

A. Tomoda, T. Miike, M. Uchino, 1994, Brain and Development.

A new phenotype of mitochondrial disease characterized by familial late-onset predominant axial myopathy and encephalopathy

K. Arimura, H. Takashima, Y. Okamoto, 2011, Acta Neuropathologica.

Pathological characteristics of skeletal muscle in Ullrich's disease with collagen VI deficiency

K. Arimura, M. Nakagawa, M. Osame, 2003, Neuromuscular Disorders.

Myopathy in a patient with systemic AA amyloidosis possibly induced by psoriasis vulgaris: An autopsy case

K. Obayashi, I. Higuchi, Y. Maki, 2015, Muscle & nerve.

Inhibition of SMG-8, a subunit of SMG-1 kinase, ameliorates nonsense-mediated mRNA decay-exacerbated mutant phenotypes without cytotoxicity

Osamu Onodera, Akio Yamashita, Shigeo Ohno, 2013, Proceedings of the National Academy of Sciences.

Microvascular endothelial abnormality in skeletal muscle from a patient with gastric cancer without dermatomyositis

K. Arimura, M. Nakagawa, M. Osame, 2000, Acta Neuropathologica.

The updated retrospective questionnaire study of sporadic inclusion body myositis in Japan

I. Nishino, R. Kaji, H. Nodera, 2019, Orphanet Journal of Rare Diseases.

Mitochondrial myopathy with autophagic vacuoles in patients with the m.8344A>G mutation

H. Takashima, A. Yoshimura, I. Higuchi, 2013, Journal of Clinical Pathology.

Characteristic Expression of Thrombomodulin in the Muscle Sarcoplasm in Patients with the Acute Phase of Rhabdomyolysis

M. Osame, I. Higuchi, M. Inose, 2000, European Neurology.

Lymphocyte subsets in muscle biopsies of human T-lymphotropic virus type I carriers with polymyositis.

S. Izumo, M. Osame, I. Higuchi, 1992, Internal medicine.

The effect of DDB on dystrophic hamsters: An in vivo and in vitro study

I. Higuchi, M. Araki, M. Tamai, 1987, Muscle & nerve.

An overexpression of fibroblast growth factor (FGF) and FGF receptor 4 in a severe clinical phenotype of facioscapulohumeral muscular dystrophy

K. Arimura, M. Osame, I. Higuchi, 2000, Muscle & nerve.

Abnormal expression of laminin suggests disturbance of sarcolemma-extracellular matrix interaction in Japanese patients with autosomal recessive muscular dystrophy deficient in adhalin.

K. Campbell, S. Roberds, M. Nakagawa, 1994, The Journal of clinical investigation.

Laminin abnormality in severe childhood autosomal recessive muscular dystrophy.

S. Roberds, T. Mitsui, K. Azibi, 1995, Laboratory investigation; a journal of technical methods and pathology.

Detection of DNA fragmentation of myonuclei in myotonic dystrophy by double staining with anti-emerin antibody and by nick end-labeling

M. Nakagawa, M. Osame, I. Higuchi, 2000, Journal of the Neurological Sciences.

Phenotypic Duchenne muscular dystrophy with C-terminal domain.

T. Moritoyo, M. Osame, I. Higuchi, 1992, Pediatric neurology.

Caveolin‐3 and sarcoglycans in the vacuolar myopathies and centronuclear myopathy

M. Osame, I. Higuchi, Masanori Nakagawa, 1999, Muscle & nerve.

Mechanomyographic determination of post-activation potentiation in myopathies

K. Arimura, M. Osame, I. Higuchi, 2006, Clinical Neurophysiology.

New missense mutation in the alpha-sarcoglycan gene in a Japanese patient with severe childhood autosomal recessive muscular dystrophy with incomplete alpha-sarcoglycan deficiency

K. Arimura, M. Nakagawa, M. Osame, 1997, Journal of the Neurological Sciences.

Histochemical and ultrastructural pathology of skeletal muscle in a patient with abetalipoproteinemia

M. Osame, I. Higuchi, M. Kuriyama, 2004, Acta Neuropathologica.

Statistically significant differences in the number of CD24 positive muscle fibers and satellite cells between sarcoglycanopathy and age-matched Becker muscular dystrophy patients.

K. Arimura, M. Nakagawa, M. Osame, 1999, Internal medicine.

Type I muscle atrophy caused by microgravity‐induced decrease of myocyte enhancer factor 2C (MEF2C) protein expression

S Masuda, I Maruyama, M. Yamakuchi, 2000, FEBS letters.

Mitochondrial abnormalities in extraocular muscles in myotonic dystrophy

M. Nakagawa, N. Ohba, Y. Isashiki, 1989 .

A case of paternally inherited congenital myotonic dystrophy.

T. Miki, M. Nakagawa, T. Miki, 1994, Journal of medical genetics.

DDB suppresses the rate of release of creatine kinase from muscle accelerated by dimethylformamide in vitro

I. Higuchi, H. Sugita, M. Araki, 1986 .

Characteristics of dynamic mutation in Japanese myotonic dystrophy

T. Ogihara, M. Nakagawa, T. Miki, 1994, Japanese Journal of Human Genetics.

Experimental germinaium dioxide-induced neuropathy in rats

S. Izumo, M. Osame, I. Higuchi, 2004, Acta Neuropathologica.

Changes in the supporting muscles of the fractured hip in elderly women.

I. Higuchi, F. Higuchi, I. Kondo, 2002, Bone.

Mitochondrial myopathy and familial thiamine deficiency

E. Naito, M. Osame, I. Higuchi, 2000, Muscle & nerve.

Clinicopathological features of the first Asian family having vocal cord and pharyngeal weakness with distal myopathy due to a MATR3 mutation

S. Tsuji, S. Morishita, Y. Ando, 2015, Neuropathology and applied neurobiology.

[n-Hexane polyneuropathy presenting with CIDP-like features].

K. Arimura, E. Matsuura, M. Osame, 2006, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

Expression of thrombomodulin, caveolin‐3, and desmin on muscle fibers in neuromuscular diseases

M. Osame, I. Higuchi, I. Maruyama, 1999, Muscle & nerve.

Adult onset limb-girdle type mitochondrial myopathy with a mitochondrial DNA np8291 A-to-G substitution

M. Nakagawa, M. Osame, I. Higuchi, 1999, Journal of Human Genetics.

Immunohistochemistry of the monkey retina with a monoclonal antibody against subunit V of cytochrome c oxidase

I. Higuchi, Masanori Nakagawa, Yasushi Isashiki, 1991, Acta ophthalmologica.

(Pro)renin receptor accelerates development of sarcopenia via activation of Wnt/YAP signaling axis

A. Nishiyama, K. Fukuda, J. Endo, 2019, Aging cell.

Electron microscopic abnormalities of skeletal muscle in patients with collagen VI deficiency in Ullrich's disease

I. Maruyama, K. Arimura, M. Nakagawa, 2002, Acta Neuropathologica.

Morphologic findings in biopsied skeletal muscle and cultured fibroblasts from a female patient with Danon's disease (lysosomal glycogen storage disease without acid maltase deficiency)

M. Nakagawa, M. Osame, I. Higuchi, 1994, Journal of the Neurological Sciences.

[A family case of HAM and HTLV-I carrier including two sisters presenting with myositis].

I. Higuchi, M. Nagai, Y. Hokezu, 1994, Rinshō shinkeigaku Clinical neurology.

Clinical presentation of axial myopathy in two siblings with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

E. Matsuura, H. Takashima, A. Yoshimura, 2015, BMC Neurology.

Diagnosis of dystrophinopathy by skin biopsy

M. Osame, I. Higuchi, T. Matsumura, 2002, Muscle & nerve.

Epidemiology of progressive muscular dystrophy in Okinawa, Japan. Classification with molecular biological techniques.

M. Osame, K. Nakahara, I. Higuchi, 1991, Neuroepidemiology.

Antibodies to potassium channels pc12 in serum of Isaacs' syndrome: Western blot and immunohistochemical studies

I. Kitajima, K. Arimura, M. Osame, 1997, Muscle & nerve.

Detection of HTLV type I provirus by in situ polymerase chain reaction in mouthwash mononuclear cells of HAM/TSP patients and HTLV type I carriers.

A. Achiron, S. Izumo, M. Osame, 1997, AIDS research and human retroviruses.

Effect of isolated AMP deaminase deficiency on skeletal muscle function☆

S. Matsuo, Jidong Cheng, I. Hisatome, 2014, Molecular genetics and metabolism reports.

First missense mutations (R388W and R425H) of AMPD1 accompanied with myopathy found in a Japanese patient

T. Morisaki, H. Morisaki, M. Osame, 2000, Human mutation.

Fatigue and damage to the masseter muscle by prolonged low-frequency stimulation in the rat.

S. Harada, G. Ito, M. Osame, 2005, Archives of oral biology.

[Eosinophilic polymyositis].

I. Higuchi, A. Saito, 2001, Ryoikibetsu shokogun shirizu.

Recent studies on the epidemiology, clinical features and pathogenic mechanisms of HTLV-I associated myelopathy (HAM/TSP) and other diseases associated to HTLV.

K. Arimura, M. Nakagawa, S. Izumo, 1997, Journal of neurovirology.

Familial skeletal myopathy with atrioventricular block.

M. Nakagawa, M. Osame, I. Higuchi, 1999, Internal medicine.

Familial mitochondrial encephalomyopathy with deaf‐mutism, ophthalmoplegia and leukodvstrophy.

Y. Isashiki, M. Osame, I. Higuchi, 1995, Acta neurologica Scandinavica.

Behçet's disease and Sjögren syndrome in a patient with HTLV-I-associated myelopathy

M. Nakagawa, M. Osame, I. Higuchi, 1993, Journal of the Neurological Sciences.

Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats

M. Okita, I. Higuchi, J. Nakano, 2019, Front. Physiol..

Proteolysis of β-dystroglycan in muscular diseases

I. Nishino, K. Matsumura, I. Higuchi, 2005, Neuromuscular Disorders.

Novel mutations identified in patients with a mild phenotype of Ullrich congenital muscular dystrophy through targeted next‐generation sequencing

K. Arimura, E. Matsuura, H. Takashima, 2013 .

Muscle MRI of the Upper Extremity in the Myotonic Dystrophy Type 1

H. Kimura, I. Higuchi, M. Ikawa, 2016, European Neurology.