Deanne F. Stolarik

发表

Mechanistic Dissection of PARP1 Trapping and the Impact on In Vivo Tolerability and Efficacy of PARP Inhibitors

Yan Shi, S. C. Panchal, Eric F. Johnson, 2015, Molecular Cancer Research.

Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.

K. Longenecker, Jyoti R. Patel, H. Sham, 2007, Bioorganic & medicinal chemistry letters.

Chemical Renal Denervation in the Rat

Deanne F. Stolarik, D. Davalian, M. Rieser, 2014, CardioVascular and Interventional Radiology.

Assessing the impact of endogenously derived crystalline drug on the in vivo performance of amorphous formulations.

Geoff G. Z. Zhang, N. Trasi, L. S. Taylor, 2019, Molecular pharmaceutics.

Measuring drug absorption improves interpretation of behavioral responses in a larval zebrafish locomotor assay for predicting seizure liability.

Pankajkumar Sancheti, B. Leroy, A. Olson, 2017, Journal of pharmacological and toxicological methods.

Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction.

Deanne F. Stolarik, S. Fung, Katina Monzon, 2006, Bioorganic & medicinal chemistry letters.

From the Cover: Inhibitors of Nicotinamide Phosphoribosyltransferase Cause Retinal Damage in Larval Zebrafish

K. Longenecker, R. Peterson, S. Fossey, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Adamantane sulfone and sulfonamide 11-β-HSD1 Inhibitors

K. Longenecker, R. Judge, Deanne F. Stolarik, 2007 .

Relationship between amorphous solid dispersion in vivo absorption and in vitro dissolution: phase behavior during dissolution, speciation, and membrane mass transport

Geoff G. Z. Zhang, L. S. Taylor, Wenqing Gao, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.

R. Henry, H. Sham, D. Beno, 2007, Journal of medicinal chemistry.

Discovery of orally active butyrolactam 11β-HSD1 inhibitors

E. Bush, Deanne F. Stolarik, S. Fung, 2006 .

Overcoming Bioavailability Challenges of Dasabuvir and Enabling a Triple-Combination Direct-Acting Antiviral HCV Regimen through a Salt of Very Weak Acid for Oral Delivery.

Ahmad Y. Sheikh, Geoff G. Z. Zhang, R. Henry, 2022, Molecular pharmaceutics.

Pharmacokinetics of sustained-release and transdermal buprenorphine in Göttingen minipigs (Sus scrofa domestica).

Deanne F. Stolarik, Gary J. Jenkins, Junli Ma, 2014, Journal of the American Association for Laboratory Animal Science : JAALAS.

Clinical efficacy of sustained-release buprenorphine with meloxicam for postoperative analgesia in beagle dogs undergoing ovariohysterectomy.

Deanne F. Stolarik, Gary J. Jenkins, Amanda S Wilsey, 2014, Journal of the American Association for Laboratory Animal Science : JAALAS.

Amorphous solid dispersions of enzalutamide and novel polysaccharide derivatives: investigation of relationships between polymer structure and performance

Geoff G. Z. Zhang, L. S. Taylor, Yifan Dong, 2020, Scientific Reports.

Prodrug Strategies to Improve the Solubility of HCV NS5A Inhibitor Pibrentasvir (ABT-530).

Brice E. Uno, J. Randolph, Deanne F. Stolarik, 2020, Journal of medicinal chemistry.

Expanding the Repertoire for “Large Small Molecules”: Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers

Ahmad Y. Sheikh, Richard S. Hong, Geoff G. Z. Zhang, 2021, Molecular Cancer Therapeutics.

Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity

A. Hoerauf, D. Kempf, S. Ward, 2019, PLoS neglected tropical diseases.

246 PARP inhibitors trap PARP1 onto damaged DNA via catalytic inhibition and not by an allosteric mechanism

Eric F. Johnson, E. DiGiammarino, L. Solomon, 2014 .

Foslevodopa/Foscarbidopa: A New Subcutaneous Treatment for Parkinson's Disease

M. Facheris, Geoff G. Z. Zhang, F. Jameel, 2021, Annals of neurology.

The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class.

R. Ulrich, P. Wiedeman, K. Marsh, 2002, Bioorganic & medicinal chemistry letters.

Highlights of the Structure-Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530).

A. C. Krueger, T. Pilot‐Matias, J. Randolph, 2018, Journal of medicinal chemistry.

Discovery of 2-aminoisobutyric acid ethyl ester (AIBEE) phosphoramidate prodrugs for delivering nucleoside HCV NS5B polymerase inhibitors.

J. Randolph, Hui-ju Chen, Deanne F. Stolarik, 2020, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of 2'-dihalo ribonucleotide prodrugs with activity against hepatitis C virus.

J. Randolph, R. Henry, Hui-ju Chen, 2019, Bioorganic & medicinal chemistry.

Modeling of relationships between pharmacokinetics and blockade of agonist-induced elevation of intraurethral pressure and mean arterial pressure in conscious dogs treated with alpha(1)-adrenoceptor antagonists.

A. Hancock, K. Marsh, Deanne F. Stolarik, 2002, The Journal of pharmacology and experimental therapeutics.

Mechanistic Dissection of PARP 1 Trapping and the Impacton InVivo TolerabilityandEf fi cacyofPARP Inhibitors

Eric F. Johnson, J. Wilsbacher, E. DiGiammarino, 2015 .

Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo.

Mikkel A. Algire, Chaohong Sun, J. Randolph, 2023, Journal of medicinal chemistry.

Discovery of fluorobenzimidazole HCV NS5A inhibitors.

T. Pilot‐Matias, J. Randolph, D. Beno, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of heterocycle containing adamantane 11β-HSD1 inhibitors

Jyoti R. Patel, H. Sham, D. Beno, 2006 .

Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.

K. Longenecker, R. Judge, Deanne F. Stolarik, 2007, Bioorganic & medicinal chemistry letters.

Discovery of orally active butyrolactam 11beta-HSD1 inhibitors.

E. Bush, Deanne F. Stolarik, S. Fung, 2006, Bioorganic & medicinal chemistry letters.